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Lucy Jones

Dr Lucy Jones

Honorary Clinical Lecturer

School of Medicine


I am an Honorary Clinical Lecturer and an Associate Specialist and my interest in medical research stems from translating research into improved patient care.

I am an experienced Chief Investigator of clinical trials and experimental medicine studies in the field of infection and immunity.

My research at the Division of Infection and Immunity includes studies examining differential immune responses to vaccines, T cell responses to viruses and vaccines, bacterial infection, anti-microbial resistance and development of novel, rapid diagnostics for detecting infection.

I work closely with the Spiller lab and T Cell research lab at Cardiff University and the R&D team at Cwm Taf Morgannwg University health board. I am supported by Health and Care Research Wales, Research Time Award.

As a clinician I work in the field of Sexual health and HIV, at Cwm Taf Morgannwg University health board.


Current research projects include:

'COVID MEMORY' Study ( Dr Lucy Jones, Professor Katja Simon, Professor Paul Klenerman, Professor Teresa Lambe, Professor Gavin Screaton, Dr Brad Spiller) University of Oxford and Cardiff University. A randomised controlled, double blinded pilot study to determine the safety of daily nutritional supplements following vaccination for Coronavirus.

The CROWN Study – 'Characterisation of the Immune Response to SARS-CoV2 Infection'. (Dr Lucy Jones, Professor Andrew Sewell, Professor Paul Klenerman, Professor Mary Carrington, Dr Brad Spiller) 2020 – 2022. Cwm Taf Morgannwg, University of Oxford, Cardiff University and NIH (USA).

'Characterisation of the Immune Response to SARS-CoV2 Infection in Type 1 diabetes'. (Professor Andrew Sewell, Dr Lucy Jones, Professor John Geen, Professor Philip Goulder,  Dr Brad Spiller and Dr Karen Logan) Cwm Taf Morgannwg University health board, Cardiff University, University of Oxford and Imperial College.

A Phase 2/3 RCT of reactogenicity of MODERNA COVID OMICRON booster vaccine
Principal Investigator for the All Wales Vaccine Research Taskforce and Public Health Wales (April 2022 – ongoing).

The 'Antibiotic Guardian Study' (Dr Lucy Jones, Dr Brad Spiller and Dr Sarah Maddocks)  Portfolio Cwm Taf Morgannwg, Cardiff University, Cardiff Metropolitan University research study (2019-ongoing).

Past  studies:

SARS-CoV-2 Immunity of Family/Household Members (Dr Lucy Jones, Professor Paul Klenerman, Professor Philip Goulder) University of   Oxford. Characterisation of the differential immune responses to SARS-CoV-2 and COVID vaccines in people aged 8 years to 90 years.

The UROGEN WELL D-ONE Study (Dr Lucy Jones and Dr Brad Spiller).  Portfolio clinical research study with Cardiff University/Cwm Taf Morgannwg health board.

The MYCOWELL D-ONE Study (Dr Lucy Jones and Dr Brad Spiller) (2019). Portfolio clinical research study Cardiff University/Cwm Taf Morgannwg health board.

Do genitourinary Mycoplasma species cause disease? (Dr Lucy Jones and Ms Rebecca Davies)  Portfolio clinical research study Cwm Taf Morgannwg health board. 2019-2020


I have a translational and experimental medicine research portfolio which focuses on developing rapid diagnostics for infection and improving our understanding of infections, vaccination and the corresponding immune response. This includes studies in Cardiff University, University of Oxford, Imperial College, Cwm Taf Morgannwg University health board and NIH.

I was born and raised in Wales and studied Physiological Sciences and Medicine at the University of Oxford. Following my medical qualification and training, I went on to complete a doctorate in the Department of Human Anatomy and Genetics, University of Oxford in the field of development and genetics with Dr Zoltan Molnar and Professor Colin Blakemore.

I have worked in Cwm Taf Morgannwg University health board for 18 years and I am an Associate Specialist and the departmental lead for research. I was made an Honorary lecturer at Cardiff University, School of Medicine in 2012 with a teaching role primarily.

Over the past few years I have moved to a research focused role and work closely with a clinical research team at the Clinical Research Centre at Cwm Taf Morgannwg University health board and collaborators at Cardiff University, University of Oxford, Imperial College, Cardiff Metropolitan University and NIH.

I also have an interest in working with industry to deliver research trials with benefits to patients in Wales. I lead the OMICRON vaccine trial for Wales in my role as an Honorary Associate Specialist with Public Health Wales. I co-supervise post-graduate students and play a role in teaching in the field of infection.


Current supervision

Martin Sharratt

Martin Sharratt

Research student