Dr Charles Evans
Research Fellow
- EvansC55@cardiff.ac.uk
- Main Building, Park Place, Cardiff, CF10 3AT
Publication
2023
- Lloyd-Evans, E. and Evans, C. 2023. Deciphering the various mechanisms of action of miglustat in the lysosomal disorders.. Presented at: 19th Annual WORLDSymposiumTM, Orlando, Florida, 21-26 February 2023, Vol. 138. Vol. 2. Elsevier pp. 84., (10.1016/j.ymgme.2022.107213)
- MacLachlan, R., Evans, C. E., Chai, S. Y., Good, M. A., Kehoe, P. G. and Miners, J. S. 2023. Age-related reduction in brain ACE-2 is not exacerbated by Alzheimer?s disease pathology in mouse models of Alzheimer?s disease. Aging Brain 3, article number: 100062. (10.1016/j.nbas.2022.100062)
2020
- Evans, C. E. et al. 2020. ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer’s disease. Acta Neuropathologica 139, pp. 485-502. (10.1007/s00401-019-02098-6)
2019
- Evans, C. E., Thomas, R. S., Freeman, T. J., Hvoslef-Eide, M., Good, M. A. and Kidd, E. J. 2019. Selective reduction of APP-BACE1 activity improves memory via NMDA-NR2B receptor-mediated mechanisms in aged PDAPP mice. Neurobiology of Aging 75, pp. 136-149. (10.1016/j.neurobiolaging.2018.11.011)
2018
- Evans, C., Hvoslefeide, M., Thomas, R., Kidd, E. and Good, M. 2018. A rapidly acquired foraging-based working memory task, sensitive to hippocampal lesions, reveals age-dependent and age-independent behavioural changes in a mouse model of amyloid pathology. Neurobiology of Learning and Memory 149, pp. 46-57. (10.1016/j.nlm.2018.02.004)
2016
- Evans, C. 2016. Evaluating 2B3, a novel immunotherapy in PDAPP model of amyloid pathology. PhD Thesis, Cardiff University.
Articles
- MacLachlan, R., Evans, C. E., Chai, S. Y., Good, M. A., Kehoe, P. G. and Miners, J. S. 2023. Age-related reduction in brain ACE-2 is not exacerbated by Alzheimer?s disease pathology in mouse models of Alzheimer?s disease. Aging Brain 3, article number: 100062. (10.1016/j.nbas.2022.100062)
- Evans, C. E. et al. 2020. ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer’s disease. Acta Neuropathologica 139, pp. 485-502. (10.1007/s00401-019-02098-6)
- Evans, C. E., Thomas, R. S., Freeman, T. J., Hvoslef-Eide, M., Good, M. A. and Kidd, E. J. 2019. Selective reduction of APP-BACE1 activity improves memory via NMDA-NR2B receptor-mediated mechanisms in aged PDAPP mice. Neurobiology of Aging 75, pp. 136-149. (10.1016/j.neurobiolaging.2018.11.011)
- Evans, C., Hvoslefeide, M., Thomas, R., Kidd, E. and Good, M. 2018. A rapidly acquired foraging-based working memory task, sensitive to hippocampal lesions, reveals age-dependent and age-independent behavioural changes in a mouse model of amyloid pathology. Neurobiology of Learning and Memory 149, pp. 46-57. (10.1016/j.nlm.2018.02.004)
Conferences
- Lloyd-Evans, E. and Evans, C. 2023. Deciphering the various mechanisms of action of miglustat in the lysosomal disorders.. Presented at: 19th Annual WORLDSymposiumTM, Orlando, Florida, 21-26 February 2023, Vol. 138. Vol. 2. Elsevier pp. 84., (10.1016/j.ymgme.2022.107213)
Thesis
- Evans, C. 2016. Evaluating 2B3, a novel immunotherapy in PDAPP model of amyloid pathology. PhD Thesis, Cardiff University.