Dr Gareth Jones
Timau a rolau for Gareth Jones
Cyhoeddiad
2025
2023
2021
2020
2019
2018
- Rivellese, F. et al., 2018. Mast cells in early rheumatoid arthritis associate with disease severity and support B-cell autoantibody production. Annals of the Rheumatic Diseases 77 (12), pp.1773-1781. (10.1136/annrheumdis-2018-213418)
- Hill, D. et al. 2018. Hyperactive gp130/STAT3-driven gastric tumourigenesis promotes submucosal tertiary lymphoid structure development. International Journal of Cancer 143 (1), pp.167-178. (10.1002/ijc.31298)
- Jones, G. et al. 2018. IL-27 - a double agent in the IL-6 family. Clinical and Experimental Immunology 193 (1), pp.37-46. (10.1111/cei.13116)
- Jones, G. et al. 2018. In Vivo models for inflammatory arthritis. In: Jenkins, B. ed. Inflammation and Cancer. Methods in Molecular Biology. Vol. 1725, Methods in Molecular Biology New York, NY: Humana Press. , pp.101-118. (10.1007/978-1-4939-7568-6_9)
2017
2016
- Clement, M. et al. 2016. Cytomegalovirus-specific IL-10-producing CD4+ T cells are governed by type-I IFN-induced IL-27 and promote virus persistence. Plos Pathogens 12 (12) e1006050. (10.1371/journal.ppat.1006050)
- Perks, W. V. et al. 2016. Death Receptor 3 promotes chemokine directed leukocyte recruitment in acute resolving inflammation and is essential for pathological development of mesothelial fibrosis in chronic disease. American Journal of Pathology 186 (11), pp.2813-2823. (10.1016/j.ajpath.2016.07.021)
- Jones, G. , Hill, D. and Jones, S. 2016. Understanding immune cells in tertiary lymphoid organ development: it is all starting to come together. Frontiers in Immunology 7 , pp.1-13. 401. (10.3389/fimmu.2016.00401)
- Patin, E. et al. 2016. IL-27 induced by Select Candida spp. via TLR7/NOD2 signaling and IFN-β production inhibits fungal clearance. The Journal of Immunology 197 (1), pp.208-221. (10.4049/jimmunol.1501204)
- Liu, X. et al. 2016. The biology behind interleukin-6 targeted
interventions. Current Opinion in Rheumatology 28 (2), pp.152-160. (10.1097/BOR.0000000000000255)
- Jones, G. W. and Jones, S. A. 2016. Ectopic lymphoid follicles: inducible centres for generating antigen-specific immune responses within tissues. Immunology 147 (2), pp.141-151. (10.1111/imm.12554)
2015
2014
2013
2012
2011
- Greenhill, C. J. et al. 2011. The regulation of arthritic bone erosions by IL-10 [Abstract]. Immunology 135 (s1), pp.158-158. (10.1111/j.1365-2567.2011.03534.x)
- Jones, G. W. et al. 2011. Interleukin-27 receptor-deficient mice develop exacerbated inflammatory arthritis associated with heightened T- and B-cell responses [Abstract]. Immunology 135 (S1), pp.158. (10.1111/j.1365-2567.2011.03534.x)
- Jones, G. W. et al. 2011. Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation. The FASEB Journal 25 (1), pp.409-419. (10.1096/fj.10-166843)
- Jones, G. W. et al. 2011. Interleukin-27 receptor-deficient mice develop exacerbated inflammatory arthritis associated with heightened T- and B- cell responses [Abstract]. Arthritis and Rheumatism 63 (s10), pp.S978-S978. (10.1002/art.33310)
- Kennedy, C. L. et al., 2011. The molecular pathogenesis of STAT3-driven gastric tumourigenesis in mice is independent of IL-17. The Journal of Pathology 225 (2), pp.255-264. (10.1002/path.2933)
2010
- Lissilaa, R. et al., 2010. Although IL-6 trans-signaling is sufficient to drive local immune responses, classical IL-6 signaling is obligate for the induction of T cell-mediated autoimmunity. The Journal of Immunology 185 (9), pp.5512-5521. (10.4049/jimmunol.1002015)
- Jones, G. W. et al. 2010. Loss of CD4+ T Cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells. The Journal of Immunology 184 (4), pp.2130-2139. (10.4049/jimmunol.0901528)
- Jones, G. W. et al. 2010. Loss of CD4(+) T cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells. Journal of Immunology 184 (4), pp.2130-2139.
- Jones, G. W. et al. 2010. Differential responsiveness of naive and activated T cells to TL1A that affect Th17 generation, maintenance and proliferation [Abstract]. Immunology 131 (s1), pp.102-102. (10.1111/j.1365-2567.2010.03390.x)
2009
2008
2007
Articles
- Jenkins, B. et al., 2025. ABHD11 inhibition drives sterol metabolism to modulate T cell effector function 2 and alleviate autoimmunity. bioRxiv (10.1101/2025.03.19.643996)
- Millrine, D. et al., 2023. Th1 cells alter the inflammatory signature of IL-6 by channeling STAT transcription factors to Alu-like retroelements. The Journal of Immunology 211 (2), pp.274-286. (10.4049/jimmunol.2300114)
- Davies, R. et al. 2021. The role of interleukin-6 trans-signalling on cardiovascular dysfunction in inflammatory arthritis. Rheumatology 60 (6), pp.2852-2861. keaa725. (10.1093/rheumatology/keaa725)
- Harbour, S. N. et al., 2020. Th17 cells require ongoing classic IL-6 receptor signaling to retain transcriptional and functional identity. Science Immunology 5 (49) eaaw2262. (10.1126/sciimmunol.aaw2262)
- Thompson, C. et al. 2020. CD28− Cells are increased in early rheumatoid arthritis and are linked with cytomegalovirus status. Frontiers in Medicine 7 129. (10.3389/fmed.2020.00129)
- Wiede, F. et al., 2019. T-cell–specific PTPN2 deficiency in NOD mice accelerates the development of type 1 diabetes and autoimmune comorbidities. Diabetes 68 (6), pp.1251-1266. (10.2337/db18-1362)
- Twohig, J. P. et al. 2019. Activation of naïve CD4+ T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4+ T cells. Nature Immunology 20 , pp.458-470. (10.1038/s41590-019-0350-0)
- Rivellese, F. et al., 2018. Mast cells in early rheumatoid arthritis associate with disease severity and support B-cell autoantibody production. Annals of the Rheumatic Diseases 77 (12), pp.1773-1781. (10.1136/annrheumdis-2018-213418)
- Hill, D. et al. 2018. Hyperactive gp130/STAT3-driven gastric tumourigenesis promotes submucosal tertiary lymphoid structure development. International Journal of Cancer 143 (1), pp.167-178. (10.1002/ijc.31298)
- Jones, G. et al. 2018. IL-27 - a double agent in the IL-6 family. Clinical and Experimental Immunology 193 (1), pp.37-46. (10.1111/cei.13116)
- Colbeck, E. J. et al., 2017. Tertiary lymphoid structures in cancer: drivers of antitumor immunity, immunosuppression, or bystander sentinels in disease?. Frontiers in Immunology 8 1830. (10.3389/fimmu.2017.01830)
- Clement, M. et al. 2016. Cytomegalovirus-specific IL-10-producing CD4+ T cells are governed by type-I IFN-induced IL-27 and promote virus persistence. Plos Pathogens 12 (12) e1006050. (10.1371/journal.ppat.1006050)
- Perks, W. V. et al. 2016. Death Receptor 3 promotes chemokine directed leukocyte recruitment in acute resolving inflammation and is essential for pathological development of mesothelial fibrosis in chronic disease. American Journal of Pathology 186 (11), pp.2813-2823. (10.1016/j.ajpath.2016.07.021)
- Jones, G. , Hill, D. and Jones, S. 2016. Understanding immune cells in tertiary lymphoid organ development: it is all starting to come together. Frontiers in Immunology 7 , pp.1-13. 401. (10.3389/fimmu.2016.00401)
- Patin, E. et al. 2016. IL-27 induced by Select Candida spp. via TLR7/NOD2 signaling and IFN-β production inhibits fungal clearance. The Journal of Immunology 197 (1), pp.208-221. (10.4049/jimmunol.1501204)
- Liu, X. et al. 2016. The biology behind interleukin-6 targeted
interventions. Current Opinion in Rheumatology 28 (2), pp.152-160. (10.1097/BOR.0000000000000255)
- Jones, G. W. and Jones, S. A. 2016. Ectopic lymphoid follicles: inducible centres for generating antigen-specific immune responses within tissues. Immunology 147 (2), pp.141-151. (10.1111/imm.12554)
- Lacroix, M. et al., 2015. Novel insights into IL-6 cis- and trans-signaling pathways by differentially manipulating the assembly of the IL-6 signaling complex. Journal of Biological Chemistry 290 , pp.26943-26953. (10.1074/jbc.M115.682138)
- Jones, G. W. et al. 2015. Interleukin-27 inhibits ectopic lymphoid-like structure development in early inflammatory arthritis. Journal of Experimental Medicine 212 (11), pp.1793-1802. (10.1084/jem.20132307)
- Jones, G. W. et al. 2015. Imbalanced gp130 signalling in ApoE-deficient mice protects against atherosclerosis. Atherosclerosis 238 (2), pp.321-328. (10.1016/j.atherosclerosis.2014.12.037)
- Greenhill, C. J. et al., 2014. Interleukin-10 regulates the inflammasome-driven augmentation of inflammatory arthritis and joint destruction. Arthritis Research and Therapy 16 (4) 419. (10.1186/s13075-014-0419-y)
- Pitzalis, C. et al., 2014. Ectopic lymphoid-like structures in infection, cancer and autoimmunity. Nature Reviews Immunology 14 (7), pp.447-462. (10.1038/nri3700)
- Jones, S. A. et al. 2014. Interleukin-6 in renal disease and therapy. Nephrology Dialysis Transplantation 30 (4), pp.564-574. (10.1093/ndt/gfu233)
- Greenhill, C. J. et al. 2013. Interleukin 10 control of the inflammasome restricts arthritic bone erosion [Abstract]. Cytokine 63 (3), pp.267. (10.1016/j.cyto.2013.06.105)
- Fielding, C. A. et al. 2013. IL-6 regulation of Th1 responses drives fibrosis in unresolved inflammation [Abstract]. Cytokine 63 (3), pp.262. (10.1016/j.cyto.2013.06.082)
- Jones, G. W. et al. 2013. Exacerbated inflammatory arthritis in response to hyperactive gp130 signalling is independent of IL-17A. Annals of the Rheumatic Diseases 72 (10), pp.1738-1742. (10.1136/annrheumdis-2013-203771)
- Orr, S. J. et al. 2013. LAB/NTAL facilitates fungal/PAMP-induced IL-12 and IFN-γ production by repressing β-catenin activation in dendritic cells. PLoS Pathogens 9 (5) e1003357. (10.1371/journal.ppat.1003357)
- Taylor, P. R. et al. 2012. Development of myeloproliferative disease in 12/15-lipoxygenase deficiency [Letter]. Blood 119 (25), pp.6173-6174. (10.1182/blood-2012-02-410928)
- Greenhill, C. et al. 2012. The regulation of arthritic bone erosions by il-10 [Abstract]. Rhuematology 51 , pp.48-48. (10.1093/rheumatology/kes117)
- Greenhill, C. J. et al. 2012. Cross-talk between IL-10 and the inflammasome regulates bone erosions during rheumatoid arthritis [Abstract]. Immunology 137 , pp.43-44.
- Jones, G. W. et al. 2012. Interleukin-27 receptor-deficient mice develop exacerbated inflammatory arthritis associated with heightened T- and B-cell responses [Abstract]. Rhuematology 51 (s3), pp.43-44. (10.1093/rheumatology/kes117)
- Greenhill, C. J. et al. 2011. The regulation of arthritic bone erosions by IL-10 [Abstract]. Immunology 135 (s1), pp.158-158. (10.1111/j.1365-2567.2011.03534.x)
- Jones, G. W. et al. 2011. Interleukin-27 receptor-deficient mice develop exacerbated inflammatory arthritis associated with heightened T- and B-cell responses [Abstract]. Immunology 135 (S1), pp.158. (10.1111/j.1365-2567.2011.03534.x)
- Jones, G. W. et al. 2011. Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation. The FASEB Journal 25 (1), pp.409-419. (10.1096/fj.10-166843)
- Jones, G. W. et al. 2011. Interleukin-27 receptor-deficient mice develop exacerbated inflammatory arthritis associated with heightened T- and B- cell responses [Abstract]. Arthritis and Rheumatism 63 (s10), pp.S978-S978. (10.1002/art.33310)
- Kennedy, C. L. et al., 2011. The molecular pathogenesis of STAT3-driven gastric tumourigenesis in mice is independent of IL-17. The Journal of Pathology 225 (2), pp.255-264. (10.1002/path.2933)
- Lissilaa, R. et al., 2010. Although IL-6 trans-signaling is sufficient to drive local immune responses, classical IL-6 signaling is obligate for the induction of T cell-mediated autoimmunity. The Journal of Immunology 185 (9), pp.5512-5521. (10.4049/jimmunol.1002015)
- Jones, G. W. et al. 2010. Loss of CD4+ T Cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells. The Journal of Immunology 184 (4), pp.2130-2139. (10.4049/jimmunol.0901528)
- Jones, G. W. et al. 2010. Loss of CD4(+) T cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells. Journal of Immunology 184 (4), pp.2130-2139.
- Jones, G. W. et al. 2010. Differential responsiveness of naive and activated T cells to TL1A that affect Th17 generation, maintenance and proliferation [Abstract]. Immunology 131 (s1), pp.102-102. (10.1111/j.1365-2567.2010.03390.x)
- Nowell, M. A. et al. 2009. Therapeutic targeting of IL-6 trans signaling counteracts STAT3 control of experimental inflammatory arthritis. Journal of Immunology 182 (1), pp.613-622.
- Longhi, M. P. et al., 2008. Interleukin-6 is crucial for recall of influenza-specific memory cd4+ t cells. PLoS Pathogens 4 (2) e1000006. (10.1371/journal.ppat.1000006)
- Jones, S. A. et al. 2008. Appreciating the balance between classical interleukin (IL)-6 receptor signaling and IL-6 trans-signaling: implications for arthritis progression. Immunology Endocrine & Metabolic Agents in Medicinal Chemistry 8 (3), pp.235-246.
- Jones, G. W. et al. 2008. TL1A negatively regulates development of T helper 17 cells [Abstract]. Rheumatology 47 (S2), pp.II20-II20. (10.1093/rheumatology/kem509)
- Jones, G. W. et al. 2008. TL1A/TNFSF15 promotes a STAT1-mediated suppression of IL-17-secreting T-helper cells [Abstract]. Immunology 125 (s1), pp.62-62. (10.1111/j.1365-2567.2008.02974.x)
- Jones, G. W. et al. 2007. TL1A counteracts the IL-6 control of the STAT3-mediated development of T helper 17 cells [Abstract]. Cytokine 39 (1), pp.18-19.
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