Dr Jason Webber

2026

• Veiga, S. et al., 2026. Heparan sulphate glycosaminoglycan chains contribute to the tethering of coronal factors and are important for extracellular vesicle‐mediated fibroblast activation. Journal of Extracellular Biology 5 (5) e70146. (10.1002/jex2.70146)

2024

• Bordanaba-Florit, G. et al., 2024. Integration of proteomic and metabolomic analysis reveal distinct metabolic alterations of prostate cancer-associated fibroblasts compared to normal fibroblasts from patient's stroma samples. BBA - Molecular Basis of Disease 1870 (6) 167229. (10.1016/j.bbadis.2024.167229)

2023

• Bhaoighill, M. N. et al., 2023. Tuberous Sclerosis Complex cell-derived EVs have an altered protein cargo capable of regulating their microenvironment and have potential as disease biomarkers. Journal of Extracellular Vesicles 12 (6) 12336. (10.1002/jev2.12336)

2021

• Lanning, B. et al. 2021. Prostate cancer cell extracellular vesicles increase mineralisation of bone osteoblast precursor cells in an in vitro model. Biology 10 (4) 318. (10.3390/biology10040318)

2020

• Rosas, M. et al. 2020. The procoagulant activity of tissue factor expressed on fibroblasts is increased by tissue factor-negative extracellular vesicles. PLoS ONE 15 (10) e0240189. (10.1371/journal.pone.0240189)
• Bliss, C. M. et al. 2020. Targeting antigen to the surface of EVs improves the in vivo immunogenicity of human and non-human adenoviral vaccines in mice. Molecular Therapy - Methods and Clinical Development 16 , pp.108-125. (10.1016/j.omtm.2019.12.003)

2018

• Théry, C. et al., 2018. Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines. Journal of Extracellular Vesicles 7 (1) 1535750. (10.1080/20013078.2018.1535750)
• Clayton, A. et al. 2018. Summary of the ISEV workshop on extracellular vesicles as disease biomarkers, held in Birmingham, UK, during December 2017. Journal of Extracellular Vesicles 7 (1) 1473707. (10.1080/20013078.2018.1473707)
• Yeung, V. et al. 2018. Rab35-dependent extracellular nanovesicles are required for induction of tumour supporting stroma. Nanoscale 10 (18), pp.8547-8559. (10.1039/C8NR02417K)

2017

• Roberts-Dalton, H. D. et al. 2017. Fluorescence labelling of extracellular vesicles using a novel thiol-based strategy for quantitative analysis of cellular delivery and intracellular traffic. Nanoscale 9 (36), pp.13693-13706. (10.1039/C7NR04128D)
• Salimu, J. et al., 2017. Dominant immunosuppression of dendritic cell function by prostate-cancer-derived exosomes. Journal of Extracellular Vesicles 6 (1) 1368823. (10.1080/20013078.2017.1368823)

2016

• Welton, J. L. et al., 2016. Proteomics analysis of vesicles isolated from plasma and urine of prostate cancer patients using a multiplex, aptamer-based protein array. Journal of Extracellular Vesicles 5 31209. (10.3402/jev.v5.31209)
• Webber, J. P. et al. 2016. Prostate stromal cell proteomics analysis discriminates normal from tumour reactive stromal phenotypes. Oncotarget 7 , pp.20124-20139. (10.18632/oncotarget.7716)

2015

• Webber, J. P. , Yeung, V. and Clayton, A. 2015. Extracellular vesicles as modulators of the cancer microenvironment. Seminars in Cell and Developmental Biology 40 , pp.27-34. (10.1016/j.semcdb.2015.01.013)
• Welton, J. L. et al. 2015. Ready-made chromatography columns for extracellular vesicle isolation from plasma. Journal of Extracellular Vesicles 4 27269. (10.3402/jev.v4.27269)
• Chowdhury, R. et al. 2015. Cancer exosomes trigger mesenchymal stem cell differentiation into pro-angiogenic and pro-invasive myofibroblasts. Oncotarget 6 (2), pp.715-731. (10.18632/oncotarget.2711)
• Webber, J. P. et al. 2015. Differentiation of tumour-promoting stromal myofibroblasts by cancer exosomes. Oncogene 34 (3), pp.290-302. (10.1038/onc.2013.560)

2014

• Spary, L. K. et al. 2014. Tumor stroma-derived factors skew monocyte to dendritic cell differentiation toward a suppressive CD14+PD-L1+phenotype in prostate cancer. OncoImmunology 3 (9) e955331. (10.4161/21624011.2014.955331)
• Webber, J. et al. 2014. Proteomics analysis of cancer exosomes using a novel modified aptamer-based array (SOMAscanTM) platform. Molecular and Cellular Proteomics 13 (4), pp.1050-1064. (10.1074/mcp.M113.032136)

2013

• Webber, J. P. and Clayton, A. 2013. How pure are your vesicles?. Journal of Extracellular Vesicles 2 19861. (10.3402/jev.v2i0.19861)

2012

• Shah, K. M. et al., 2012. Induction of microRNA resistance and secretion in differentiating human endometrial stromal cells [Letter]. Journal of Molecular Cell Biology 5 (1), pp.67-70. (10.1093/jmcb/mjs058)

2011

• Clayton, A. et al. 2011. Cancer exosomes express CD39 and CD73, which suppress T cells through adenosine production. The Journal of Immunology 187 (2), pp.676-683. (10.4049/jimmunol.1003884)
• Michael, D. R. et al. 2011. The human hyaluronan synthase 2 (HAS2) gene and its natural antisense RNA exhibit coordinated expression in the renal proximal tubular epithelial cell. Journal of Biological Chemistry 286 (22), pp.19523-19532. (10.1074/jbc.M111.233916)

2010

• Webber, J. P. et al. 2010. Cancer exosomes trigger fibroblast to myofibroblast differentiation. Cancer Research 70 (23), pp.9621-9630. (10.1158/0008-5472.CAN-10-1722)

2009

• Zhang, L. et al. 2009. Thyrotropin receptor activation increases hyaluronan production in preadipocyte fibroblasts: Contributory role in hyaluronan accumulation in thyroid dysfunction. Journal of Biological Chemistry 284 (39), pp.26447-26455. (10.1074/jbc.M109.003616)
• Webber, J. P. et al. 2009. Modulation of TGFβ1-dependent myofibroblast differentiation by hyaluronan. American Journal of Pathology 175 (1), pp.148-160. (10.2353/ajpath.2009.080837)
• Webber, J. P. et al. 2009. Hyaluronan orchestrates transforming growth factor-β1-dependent maintenance of myofibroblast phenotype. Journal of Biological Chemistry 284 (14), pp.9083-9092. (10.1074/jbc.M806989200)