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Research Group: Inorganic Chemistry
Research Interests
Dr Dervisi$acirc; s research interests include the synthesis and coordination of functionalised ligands, such as phosphines and NHC carbenes and their catalytic, biological and optoelectronic applications.
Much of our ligand design takes inspiration from the hydrocarbon chiral pool (sugars in particular). Such ligands offer the advantages of predetermined backbone chirality with often rigid structure and high degree of peripheral functionalisation. As an example, chelating diphosphine and N-heterocyclic carbene ligands have been derived from D-isomannide, a mannitol dehydration product. In this case we have taken advantage of the predetermined backbone chirality of a naturally occurring polyol (mannitol) and have prepared highly functional ligands with multiple chiral centres in just two synthetic steps.
Another area of interest is the study of the electronic and steric properties of large ring (>5) N-heterocyclic carbene ligands. In this area we have contributed in the understanding of the factors affecting the stability of such NHC ligands and their applications in catalysis.
For more information, click on the 'Research' tab above.
Teaching
CH0001 Fundamental Aspects of Chemistry
CH3102 Foundations of Inorganic Chemistry
CH3104 Introduction to the Solid State and Applications of Spectroscopy
Cyhoeddiad
2022
- Ali, H. et al. 2022. Interfacial activity and micellar morphology of an imidazolium ring containing zwitterionic surfactants. Journal of Surfactants and Detergents 25(3), pp. 341-350. (10.1002/jsde.12573)
2018
- Hallett, A. J. et al. 2018. Exploring the cellular uptake and localisation of phosphorescent rhenium fac-tricarbonyl metallosurfactants as a function of lipophilicity. Dalton Transactions 47(40), pp. 14241-14253. (10.1039/C8DT00669E)
2013
- Almalioti, F. et al. 2013. Convenient syntheses of cyanuric chloride-derived NHC ligands, their Ag(i) and Au(i) complexes and antimicrobial activity. Dalton Transactions 42(34), pp. 12370-12380. (10.1039/c3dt51400e)
2012
- Phillips, N. et al. 2012. Sterically encumbered iridium Bis(N-heterocyclic carbene) complexes: Air-stable 14-electron cations and facile degenerate C-H activation. Organometallics 31(23), pp. 8075-8078. (10.1021/om301060h)
- Marshall, P. et al. 2012. Chiral Ag(I) and Pt(II) complexes of ditopic NHC ligands: synthesis, structural and spectroscopic properties. Dalton Transactions 2012(41), pp. 12839-12846. (10.1039/C2DT31740K)
2011
- Carcedo, C., Knight, J. C., Pope, S. J. A., Fallis, I. A. and Dervisi, A. 2011. Chiral silver and gold rings: synthesis and structural, spectroscopic, and photophysical properties of Ag and Au metallamacrocycles of bridging NHC ligands. Organometallics 30(9), pp. 2553-2562. (10.1021/om200125w)
- Dervisi, A. 2011. Nickel, palladium and platinum. Annual Reports on the Progress of Chemistry - Section A 107, pp. 209-220. (10.1039/c1ic90032c)
2010
- Binobaid, A. A., Iglesias, M. A., Beetstra, D. J., Dervisi, A., Fallis, I. A. and Cavell, K. J. 2010. Donor-Functionalised Expanded Ring N-Heterocyclic Carbenes: Highly Effective Ligands in Ir-Catalysed Transfer Hydrogenation. European Journal of Inorganic Chemistry(34), pp. 5426-5431. (10.1002/ejic.201000680)
- Iglesias, M. A. et al. 2010. Expanded-ring and backbone-functionalised N-heterocyclic carbenes. European Journal of Inorganic Chemistry 2010(11), pp. 1604-1607. (10.1002/ejic.200901182)
- Dervisi, A. 2010. Nickel, palladium and platinum. Annual Reports on the Progress of Chemistry - Section A 106, pp. 223-234. (10.1039/b918385j)
2009
- Binobaid, A. A., Iglesias, M. A., Beetstra, D. J., Kariuki, B., Dervisi, A., Fallis, I. A. and Cavell, K. J. 2009. Expanded ring and functionalised expanded ring N-heterocyclic carbenes as ligands in catalysis. Dalton Transactions(35), pp. 7099-7112. (10.1039/b909834h)
- Dervisi, A. 2009. Nickel, palladium and platinum. Annual Reports on the Progress of Chemistry - Section A 105, pp. 248-260. (10.1039/b818264g)
- Iglesias, M. A., Beetstra, D. J., Kariuki, B., Cavell, K. J., Dervisi, A. and Fallis, I. A. 2009. Synthesis and structural features of rhodium complexes of expanded ring N-heterocyclic carbenes. European Journal of Inorganic Chemistry 2009(13), pp. 1913-1919. (10.1002/ejic.200801179)
2008
- Iglesias, M. A. et al. 2008. Novel expanded ring N-heterocyclic carbenes: free carbenes, silver complexes, and structures. Organometallics 27(13), pp. 3279-3289. (10.1021/om800179t)
2000
- Dervisi, A., Edwards, P. G., Newman, P. D. and Tooze, R. P. 2000. Synthesis and chemistry of diphenyl-2-pyridylphosphine complexes of palladium(0). X-Ray characterisation of Pd(Ph2Ppy)2(?2-DMAD) and trans-Pd(Ph2Ppy)2(PhC?CH2)(CF3CO2). Journal of the Chemical Society, Dalton Transactions 2000(4), pp. 523-528. (10.1039/a908050c)
1999
- Dervisi, A., Edwards, P. G., Newman, P. D., Tooze, R. P., Coles, S. J. and Hursthouse, M. B. 1999. Comments on the catalytic alkoxycarbonylation of alkynes. Journal of the Chemical Society. Dalton Transactions 1999(7), pp. 1113-1120. (10.1039/a809624d)
Erthyglau
- Ali, H. et al. 2022. Interfacial activity and micellar morphology of an imidazolium ring containing zwitterionic surfactants. Journal of Surfactants and Detergents 25(3), pp. 341-350. (10.1002/jsde.12573)
- Hallett, A. J. et al. 2018. Exploring the cellular uptake and localisation of phosphorescent rhenium fac-tricarbonyl metallosurfactants as a function of lipophilicity. Dalton Transactions 47(40), pp. 14241-14253. (10.1039/C8DT00669E)
- Almalioti, F. et al. 2013. Convenient syntheses of cyanuric chloride-derived NHC ligands, their Ag(i) and Au(i) complexes and antimicrobial activity. Dalton Transactions 42(34), pp. 12370-12380. (10.1039/c3dt51400e)
- Phillips, N. et al. 2012. Sterically encumbered iridium Bis(N-heterocyclic carbene) complexes: Air-stable 14-electron cations and facile degenerate C-H activation. Organometallics 31(23), pp. 8075-8078. (10.1021/om301060h)
- Marshall, P. et al. 2012. Chiral Ag(I) and Pt(II) complexes of ditopic NHC ligands: synthesis, structural and spectroscopic properties. Dalton Transactions 2012(41), pp. 12839-12846. (10.1039/C2DT31740K)
- Carcedo, C., Knight, J. C., Pope, S. J. A., Fallis, I. A. and Dervisi, A. 2011. Chiral silver and gold rings: synthesis and structural, spectroscopic, and photophysical properties of Ag and Au metallamacrocycles of bridging NHC ligands. Organometallics 30(9), pp. 2553-2562. (10.1021/om200125w)
- Dervisi, A. 2011. Nickel, palladium and platinum. Annual Reports on the Progress of Chemistry - Section A 107, pp. 209-220. (10.1039/c1ic90032c)
- Binobaid, A. A., Iglesias, M. A., Beetstra, D. J., Dervisi, A., Fallis, I. A. and Cavell, K. J. 2010. Donor-Functionalised Expanded Ring N-Heterocyclic Carbenes: Highly Effective Ligands in Ir-Catalysed Transfer Hydrogenation. European Journal of Inorganic Chemistry(34), pp. 5426-5431. (10.1002/ejic.201000680)
- Iglesias, M. A. et al. 2010. Expanded-ring and backbone-functionalised N-heterocyclic carbenes. European Journal of Inorganic Chemistry 2010(11), pp. 1604-1607. (10.1002/ejic.200901182)
- Dervisi, A. 2010. Nickel, palladium and platinum. Annual Reports on the Progress of Chemistry - Section A 106, pp. 223-234. (10.1039/b918385j)
- Binobaid, A. A., Iglesias, M. A., Beetstra, D. J., Kariuki, B., Dervisi, A., Fallis, I. A. and Cavell, K. J. 2009. Expanded ring and functionalised expanded ring N-heterocyclic carbenes as ligands in catalysis. Dalton Transactions(35), pp. 7099-7112. (10.1039/b909834h)
- Dervisi, A. 2009. Nickel, palladium and platinum. Annual Reports on the Progress of Chemistry - Section A 105, pp. 248-260. (10.1039/b818264g)
- Iglesias, M. A., Beetstra, D. J., Kariuki, B., Cavell, K. J., Dervisi, A. and Fallis, I. A. 2009. Synthesis and structural features of rhodium complexes of expanded ring N-heterocyclic carbenes. European Journal of Inorganic Chemistry 2009(13), pp. 1913-1919. (10.1002/ejic.200801179)
- Iglesias, M. A. et al. 2008. Novel expanded ring N-heterocyclic carbenes: free carbenes, silver complexes, and structures. Organometallics 27(13), pp. 3279-3289. (10.1021/om800179t)
- Dervisi, A., Edwards, P. G., Newman, P. D. and Tooze, R. P. 2000. Synthesis and chemistry of diphenyl-2-pyridylphosphine complexes of palladium(0). X-Ray characterisation of Pd(Ph2Ppy)2(?2-DMAD) and trans-Pd(Ph2Ppy)2(PhC?CH2)(CF3CO2). Journal of the Chemical Society, Dalton Transactions 2000(4), pp. 523-528. (10.1039/a908050c)
- Dervisi, A., Edwards, P. G., Newman, P. D., Tooze, R. P., Coles, S. J. and Hursthouse, M. B. 1999. Comments on the catalytic alkoxycarbonylation of alkynes. Journal of the Chemical Society. Dalton Transactions 1999(7), pp. 1113-1120. (10.1039/a809624d)
- Almalioti, F. et al. 2013. Convenient syntheses of cyanuric chloride-derived NHC ligands, their Ag(i) and Au(i) complexes and antimicrobial activity. Dalton Transactions 42(34), pp. 12370-12380. (10.1039/c3dt51400e)
- Phillips, N. et al. 2012. Sterically encumbered iridium Bis(N-heterocyclic carbene) complexes: Air-stable 14-electron cations and facile degenerate C-H activation. Organometallics 31(23), pp. 8075-8078. (10.1021/om301060h)
- Marshall, P. et al. 2012. Chiral Ag(I) and Pt(II) complexes of ditopic NHC ligands: synthesis, structural and spectroscopic properties. Dalton Transactions 2012(41), pp. 12839-12846. (10.1039/C2DT31740K)
- Carcedo, C., Knight, J. C., Pope, S. J. A., Fallis, I. A. and Dervisi, A. 2011. Chiral silver and gold rings: synthesis and structural, spectroscopic, and photophysical properties of Ag and Au metallamacrocycles of bridging NHC ligands. Organometallics 30(9), pp. 2553-2562. (10.1021/om200125w)
- Dervisi, A. 2011. Nickel, palladium and platinum. Annual Reports on the Progress of Chemistry - Section A 107, pp. 209-220. (10.1039/c1ic90032c)
- Binobaid, A. A., Iglesias, M. A., Beetstra, D. J., Dervisi, A., Fallis, I. A. and Cavell, K. J. 2010. Donor-Functionalised Expanded Ring N-Heterocyclic Carbenes: Highly Effective Ligands in Ir-Catalysed Transfer Hydrogenation. European Journal of Inorganic Chemistry(34), pp. 5426-5431. (10.1002/ejic.201000680)
- Iglesias, M. A. et al. 2010. Expanded-ring and backbone-functionalised N-heterocyclic carbenes. European Journal of Inorganic Chemistry 2010(11), pp. 1604-1607. (10.1002/ejic.200901182)
- Dervisi, A. 2010. Nickel, palladium and platinum. Annual Reports on the Progress of Chemistry - Section A 106, pp. 223-234. (10.1039/b918385j)
- Binobaid, A. A., Iglesias, M. A., Beetstra, D. J., Kariuki, B., Dervisi, A., Fallis, I. A. and Cavell, K. J. 2009. Expanded ring and functionalised expanded ring N-heterocyclic carbenes as ligands in catalysis. Dalton Transactions(35), pp. 7099-7112. (10.1039/b909834h)
- Dervisi, A. 2009. Nickel, palladium and platinum. Annual Reports on the Progress of Chemistry - Section A 105, pp. 248-260. (10.1039/b818264g)
- Iglesias, M. A., Beetstra, D. J., Kariuki, B., Cavell, K. J., Dervisi, A. and Fallis, I. A. 2009. Synthesis and structural features of rhodium complexes of expanded ring N-heterocyclic carbenes. European Journal of Inorganic Chemistry 2009(13), pp. 1913-1919. (10.1002/ejic.200801179)
- Iglesias, M. A. et al. 2008. Novel expanded ring N-heterocyclic carbenes: free carbenes, silver complexes, and structures. Organometallics 27(13), pp. 3279-3289. (10.1021/om800179t)
- Dervisi, A., Edwards, P. G., Newman, P. D. and Tooze, R. P. 2000. Synthesis and chemistry of diphenyl-2-pyridylphosphine complexes of palladium(0). X-Ray characterisation of Pd(Ph2Ppy)2(?2-DMAD) and trans-Pd(Ph2Ppy)2(PhC?CH2)(CF3CO2). Journal of the Chemical Society, Dalton Transactions 2000(4), pp. 523-528. (10.1039/a908050c)
- Dervisi, A., Edwards, P. G., Newman, P. D., Tooze, R. P., Coles, S. J. and Hursthouse, M. B. 1999. Comments on the catalytic alkoxycarbonylation of alkynes. Journal of the Chemical Society. Dalton Transactions 1999(7), pp. 1113-1120. (10.1039/a809624d)
Ymchwil
Research Interests
3.3.0 bicyclic ligand frameworks
An area currently pursued in the group is the study of phosphine ligands based on 3.3.0 bicyclic frameworks. This project fits with our broader interest in the design of more rigid, sterically controlled chiral ligands derived from the hydrocarbon chiral pool (sugars in particular). Such ligands offer the advantages of predetermined backbone chirality with often rigid structure and high degree of peripheral functionalisation. Chelating diphosphine ligands derived from D-isomannide 1, a mannitol dehydration product, and their TM complexes 2 have been isolated. In this case, we have taken advantage of the predetermined backbone chirality of a naturally occurring polyol (mannitol) and prepared chelating diphosphines with 4 chiral centres in only two steps. Presently, we are in the process of preparing NHC (N-heterocyclic carbene) precursors 3 based on the isomannide framework.
Large ring N-heterocyclic Carbene Ligands
The strong s-donating properties of NHCs make them effective stabilizing ligands in organometallic chemistry as well as important ligands in some forms of catalysis. To date research has largely focused on five-membered ring carbenes. Previously, we reported the first examples of novel, saturated, seven-membered diazepanylidene carbenes and their transition metal complexes, in collaboration with Fallis & Cavell.
A simple, versatile and high yielding route from amidines was also devised, leading to 6- and 7- membered carbenes (and saturated 5-membered NHCs). This methodology allows the isolation of a range of carbenes, and hence metal complexes, which are not available via other routes.
Six-, and in particular, seven-membered ring carbenes are intriguing from several points of view. They are very basic, somewhat more basic than the saturated 5-membered-ring carbenes, which are in turn more basic than their unsaturated counterparts. Structurally they also offer some unique features. The saturated seven-membered ring is highly twisted providing an opportunity to design new chiral ligand systems and the large heterocyclic rings lead to large N-CNHC-N angles.
Hybrid P,S ligand systems
In this area we are involved in the synthesis and catalytic applications of hybrid P,S ligands; studying the effect of bulky substituents on the P,S backbone in relation to co-ordination and catalysis. Previously, we have reported their applications in palladium-catalysed C-C coupling reactions. Some of these catalysts desirable features are: air and water stability, high tofs$acirc; and catalyst recyclability. Their water stability has enabled us to develop a biphasic Heck system where simple inorganic bases such as NaOH are used instead of organic bases.
Addysgu
Bywgraffiad
PhD Cardiff University (1997, P. G. Edwards). Postdoctoral Research Fellow, Vancouver (1997, M.D. Fryzuk), Bristol University (1998, R.W. Alder). Appointed as Lecturer, Cardiff, in 1999.
Member of the Royal Society of Chemistry and Honorary Secretary of the South East Wales RSC Section.