![Lauren Hatcher BSc, PhD](https://profiles-cardiff.imgix.net/attachments/1489?w=200&h=200&auto=format&crop=faces&fit=crop&q=90")
Dr Lauren Hatcher
(hi/ei)
BSc, PhD
Cymrawd Ymchwil Prifysgol y Gymdeithas Frenhinol
- Ar gael fel goruchwyliwr ôl-raddedig
Trosolwyg
Mae ymchwil Dr Hatcher yn canolbwyntio ar astudio deunyddiau crisialog ffoto-weithredol ar y raddfa atomig. Trwy ddeall y berthynas rhwng strwythur crisial a'i eiddo swmp defnyddiol, gallwn ddylunio deunyddiau newydd yn rhesymegol gyda strwythurau wedi'u optimeiddio i dargedu cymhwysiad neu ymarferoldeb penodol .
Ochr yn ochr â diddordeb mewn ystod o ddeunyddiau moleciwlaidd y gellir eu newid, mae Dr Hatcher yn canolbwyntio ar ddatblygu deunyddiau ferroelectric sy'n ymateb i olau ar gyfer cymwysiadau ynni solar. Mae'r gwaith hwn yn cael ei gyflwyno mewn dwy ffrwd gyfochrog, gyda ffrwd un yn canolbwyntio ar ddylunio deunyddiau ac yn llifo dau ar ddatblygiad dull diffreithiant pelydr-X deinamig. Mae ffrwd un yn ymgorffori agweddau ar gemeg synthetig organig/organometalig, synthesis fframwaith, dulliau cemeg dadansoddol a thechnegau crisialu. Mae ffrwd dau yn cyfuno ystod o ddulliau diffreithiant pelydr-X yn y fan a'r lle (yn enwedig ffotocrystallography) gydag arbrofi wedi'i ddatrys gan amser, gan ddarparu gwybodaeth strwythur 3D gyflawn ar amserlenni sy'n amrywio o funudau i lawr i picoseconds.
Cyhoeddiadau dethol:
Angew. Chem. Int. Ed. (2024), Archwilio newid pyroelectric, thermol a ffotocemegol mewn grisial organig-anorganig hybrid trwy diffreithiant pelydr-X yn y fan a'r lle, https://doi.org/10.1002/anie.202401552.
Faraday yn trafod. (2023), Datgelu rôl rhyngweithiadau nad ydynt yn cofalent mewn ffotoswitshis cyflwr solid trwy buriadau strwythur an-sfferig gyda NoSpherA2, 244, 370-390.
Commun. Chem. (2022), crisialograffeg aml-aml-chwiliedydd LED-pwmp-X ar gyfer graddfeydd amser is-eiliad, 5, 102.
CrystEngComm (2022), Archwilio dylanwad cyd-ligands polymorffiaeth a chromophore ar newid llun isomer cysylltu yn [Pd(bpy4dca)(RHIF2)2]. 24, 3701-3714.
Acc. Chem. Res, (2019), Astudiaethau Ffotocrystallograffig ar Nitrito Metasefydlog Metel Pontio Isomers Linkage: Trin y Wladwriaeth Metastable, 52(4), 1079-1088.
Phys. Chem. Ffys., (2018), Monitro dynameg poblogaeth a achosir gan ffoto mewn crisialau isomer cysylltiad metastable: astudiaeth cinetig grisialograffig o [Pd(Bu4dien)RHIF2]BPh4, 20(8), 5874-5886.
Gwefan y Grŵp Ymchwil: https://hatcherresearch.wixsite.com/lehatcherresearch
Cyhoeddiad
2024
- Lewis, S. G., Coulson, B. A., Warren, A. J., Warren, M. R. and Hatcher, L. E. 2024. Small-rotative fixed-target serial synchrotron crystallography (SR-FT-SSX) for molecular crystals. Communications Chemistry 7(1), article number: 264. (10.1038/s42004-024-01360-7)
- Hatcher, L. E., Warren, M. R. and Raithby, P. R. 2024. Methods in molecular photocrystallography. Acta Crystallographica Section C: Structural Chemistry 80(10), article number: C80. (10.1107/s2053229624007460)
- Pallikara, I., Skelton, J. M., Hatcher, L. E. and Pallipurath, A. R. 2024. Going beyond the ordered bulk: A perspective on the use of the Cambridge Structural Database for predictive materials Design. Crystal Growth and Design 24(17), pp. 6911-6930. (10.1021/acs.cgd.4c00694)
- Hatcher, L. E. and Raithby, P. R. 2024. Dynamic crystal structure of a molecular framework. Nature Chemistry 16, pp. 674-675. (10.1038/s41557-024-01514-z)
- Morris, J. J. et al. 2024. Exploring pyroelectricity, thermal and photochemical switching in a hybrid organic-inorganic crystal by in situ X-ray diffraction. Angewandte Chemie International Edition 63(20), article number: e202401552. (10.1002/anie.202401552)
2023
- Bryant, M. J., Fuertes, S., Hatcher, L. E., Thomas, L. H. and Raithby, P. R. 2023. Structural modifications to platinum(ii) pincer complexes resulting in changes in their vapochromic and solvatochromic properties. Faraday Discussions 244, pp. 411-433. (10.1039/d3fd00025g)
2022
- Hatcher, L. E., Saunders, L. K. and Coulson, B. A. 2022. Uncovering the role of non-covalent interactions in solid-state photoswitches by non-spherical structure refinements with NoSpherA2. Faraday Discussions (10.1039/d2fd00158f)
- Hatcher, L. E. et al. 2022. LED-pump-X-ray-multiprobe crystallography for sub-second timescales. Communications Chemistry 5(1), article number: 102. (10.1038/s42004-022-00716-1)
- Coulson, B. A. and Hatcher, L. E. 2022. Exploring the influence of polymorphism and chromophore co-ligands on linkage isomer photoswitching in [Pd(bpy4dca)(NO2)2]. CrystEngComm 24(20), pp. 3701-3714. (10.1039/D2CE00213B)
2020
- Hatcher, L. E., Burgess, A. J., Payne, P. and Wilson, C. C. 2020. From structure to crystallisation and pharmaceutical manufacturing: the CSD in CMAC Workflows. CrystEngComm 22, pp. 7475-7489. (10.1039/D0CE00898B)
- Hatcher, L. E., Li, W., Payne, P., Benyahia, B., Rielly, C. D. and Wilson, C. C. 2020. Tuning morphology in active pharmaceutical ingredients: controlling the crystal habit of lovastatin through solvent choice and non-size-matched polymer additives. Crystal Growth and Design 20(9), pp. 5854-5862. (10.1021/acs.cgd.0c00470)
- Kaminski, R. et al. 2020. Instrument-model refinement in normalized reciprocal-vector space for X-ray Laue diffraction. Journal of Applied Crystallography 53(5), pp. 1370-1375. (10.1107/S1600576720011929)
- Charles, B. et al. 2020. Phase behavior and substitution limit of mixed cesium-formamidinium lead triiodide perovskites. Chemistry of Materials 32(6), pp. 2282-2291. (10.1021/acs.chemmater.9b04032)
- Hatcher, L. E., Warren, M. R., Pallipurath, A. R., Saunders, L. K. and Skelton, J. M. 2020. Watching photochemistry happen: recent developments in dynamic single-crystal X-ray diffraction studies. In: 21st Century Challenges in Chemical Crystallography I., Vol. 185. Structure and Bonding Springer-verlag, pp. 199-238., (10.1007/430_2020_78)
2019
- Saunders, L. K. et al. 2019. Exploring short strong hydrogen bonds engineered in organic acid molecular crystals for temperature dependent proton migration behaviour using single crystal synchrotron X-ray diffraction (SCSXRD). CrystEngComm 21(35) (10.1039/C9CE00925F)
- Turner, T. D., Hatcher, L. E., Wilson, C. C. and Roberts, K. J. 2019. Habit modification of the active pharmaceutical ingredient lovastatin through a predictive solvent selection approach. Journal of Pharmaceutical Sciences 108(5) (10.1016/j.xphs.2018.12.012)
- Hatcher, L. E., Skelton, J. M., Warren, M. R. and Raithby, P. R. 2019. Photocrystallographic studies on transition metal nitrito metastable linkage isomers: manipulating the metastable state. Accounts of Chemical Research 52(4) (10.1021/acs.accounts.9b00018)
2018
- Hatcher, L. E. 2018. Understanding solid-state photoswitching in [ReIJOMe2-bpy)IJCO)3IJη1-NO2)] crystals via in situ photocrystallography. CrystEngComm 20(39), article number: 5990. (10.1039/C8CE00774H)
- Saunders, L. K. et al. 2018. Tuning charge-assisted and weak hydrogen bonds in molecular complexes of the proton sponge DMAN by acid co-former substitution. CrystEngComm 20(22) (10.1039/C8CE00443A)
- Gee, W. J., Hatcher, L. E., Cameron, C. A., Stubbs, C., Warren, M. R., Burrows, A. D. and Raithby, P. R. 2018. Evaluating iodine uptake in a crystalline sponge using dynamic X-ray crystallography. Inorganic Chemistry 57(9), pp. 4959-4965. (10.1021/acs.inorgchem.7b03218)
- Henderson, J. et al. 2018. New polymorphs of perylene: tetracyanoquinodimethane charge transfer cocrystals. Crystal Growth and Design 18(4), pp. 2003-2009. (10.1021/acs.cgd.7b01391)
- Hatcher, L. E., Skelton, J. M., Warren, M. R., Stubbs, C., da Silva, E. L. and Raithby, P. R. 2018. Monitoring photo-induced population dynamics in metastable linkage isomer crystals: a crystallographic kinetic study of [Pd(Bu4dien)NO2]BPh4. Physical Chemistry Chemical Physics 20(8) (10.1039/C7CP05422J)
2017
- Bryant, M. J. et al. 2017. A rapidly-reversible absorptive and emissive vapochromic Pt(II) pincer-based chemical sensor. Nature Communications 8, article number: 1800. (10.1038/s41467-017-01941-2)
- Hatcher, L. E. and Raithby, P. R. 2017. The impact of hydrogen bonding on 100% photo-switching in solid-state nitro-nitrito linkage isomers. CrystEngComm 19(42) (10.1039/C7CE01366C)
2016
- Hendon, C. H. et al. 2016. Magnetic coupling in a hybrid Mn(ii) acetylene dicarboxylate. Physical Chemistry Chemical Physics 18(48) (10.1039/C6CP06886C)
- Woodall, C. H. et al. 2016. Observation of a re-entrant phase transition in the molecular complex tris(μ2-3,5-diisopropyl-1,2,4-triazolato-κ2N1:N2)trigold(I) under high pressure. IUCrJ 3(5), pp. 376. (10.1107/S2052252516013129)
- Hatcher, L. E. 2016. Raising the (metastable) bar: 100% photo-switching in [Pd(Bu4dien)(η1-O2)]+ approaches ambient temperature. CrystEngComm 18(22), pp. 4180-4187. (10.1039/C5CE02434J)
- Murray, A. T. et al. 2016. Modelling flavoenzymatic charge transfer events: development of catalytic indole deuteration strategies. Organic and Biomolecular Chemistry 14(15), pp. 3787-3792. (10.1039/C6OB00361C)
- Shepherd, H. et al. 2016. A high pressure investigation of the order-disorder phase transition and accompanying spin crossover in [FeL12](ClO4)2 (L1 = 2,6-bis{3-methylpyrazol-1-yl}-pyrazine). Magnetochemistry 2(1), pp. -., article number: 9. (10.3390/magnetochemistry2010009)
2015
- Skelton, J. M., Lora da Silva, E., Crespo-Otero, R., Hatcher, L. E., Raithby, P. R., Parker, S. C. and Walsh, A. 2015. Electronic excitations in molecular solids: bridging theory and experiment. Faraday Discussions 177 (10.1039/C4FD00168K)
- Skelton, J. M., Crespo-Otero, R., Hatcher, L. E., Parker, S. C., Raithby, P. R. and Walsh, A. 2015. Energetics, thermal isomerisation and photochemistry of the linkage-isomer system [Ni(Et4dien)(η2-O,ON)(η1-NO2)]. CrystEngComm 17(2) (10.1039/C4CE01411A)
2014
- Woodall, C. H. et al. 2014. Tunable trimers: using temperature and pressure to control luminescent emission in gold(I) pyrazolate-based trimers. Chemistry - A European Journal 20(51), pp. 16933-16942. (10.1002/chem.201404058)
- Hatcher, L. E. and Raithby, P. R. 2014. Dynamic single-crystal diffraction studies using synchrotron radiation. Coordination Chemistry Reviews 277-27, pp. 69-79. (10.1016/j.ccr.2014.02.021)
- Hatcher, L. E. et al. 2014. Thermal and photochemical control of nitro-nitrito linkage isomerism in single-crystals of [Ni(medpt)(NO2)(η2-ONO]. CrystEngComm 16(35) (10.1039/C4CE00675E)
- Hatcher, L. E. et al. 2014. Steady‐state and pseudo‐steady‐state photocrystallographic studies on linkageiIsomers of [Ni(Et4dien)(η2‐O,ON)(η1‐NO2)]: identification of a new linkage isomer. Chemistry - A European Journal 20(11), pp. 3128-3134. (10.1002/chem.201304172)
2013
- Hatcher, L. E. and Raithby, P. R. 2013. Solid-state photochemistry of molecular photo-switchable species: the role of photocrystallographic techniques. Acta Crystallographica Section C: Crystal Structure Communications 69(12) (10.1107/S010827011303223X)
- Woodall, C. H. et al. 2013. Hingeless negative linear compression in the mechanochromic gold complex [(C6F5Au)2(μ‐1,4‐diisocyanobenzene)]. Angewandte Chemie International Edition 52(37) (10.1002/anie.201302825)
2012
- Jarvis, A. G. et al. 2012. Photochemical-mediated solid-state [2+2]-cycloaddition reactions of an unsymmetrical dibenzylidene acetone (monothiophos-dba). CrystEngComm 14(17) (10.1039/c2ce25480h)
- Warren, M. R. et al. 2012. Photoactivated linkage isomerism in single crystals of nickel, palladium and platinum di-nitro complexes – a photocrystallographic investigation. Dalton Transactions 41(42) (10.1039/c2dt30314k)
- Bajwa, S. E. et al. 2012. On the appearance of nitrite anion in [PdX(OAc)L2] and [Pd(X)(C^N)L] syntheses (X = OAc or NO2): photocrystallographic identification of metastable Pd(η1-ONO)(C^N)PPh3. Chemical Science 3(5) (10.1039/c2sc01050j)
2011
- Hatcher, L. E. et al. 2011. Metastable linkage isomerism in [Ni(Et4dien)(NO2)2]: a combined thermal and photocrystallographic structural investigation of a Nitro/Nitrito interconversion. Angewandte Chemie International Edition 50(36), pp. 8371-8374. (10.1002/anie.201102022)
Adrannau llyfrau
- Hatcher, L. E., Warren, M. R., Pallipurath, A. R., Saunders, L. K. and Skelton, J. M. 2020. Watching photochemistry happen: recent developments in dynamic single-crystal X-ray diffraction studies. In: 21st Century Challenges in Chemical Crystallography I., Vol. 185. Structure and Bonding Springer-verlag, pp. 199-238., (10.1007/430_2020_78)
Erthyglau
- Lewis, S. G., Coulson, B. A., Warren, A. J., Warren, M. R. and Hatcher, L. E. 2024. Small-rotative fixed-target serial synchrotron crystallography (SR-FT-SSX) for molecular crystals. Communications Chemistry 7(1), article number: 264. (10.1038/s42004-024-01360-7)
- Hatcher, L. E., Warren, M. R. and Raithby, P. R. 2024. Methods in molecular photocrystallography. Acta Crystallographica Section C: Structural Chemistry 80(10), article number: C80. (10.1107/s2053229624007460)
- Pallikara, I., Skelton, J. M., Hatcher, L. E. and Pallipurath, A. R. 2024. Going beyond the ordered bulk: A perspective on the use of the Cambridge Structural Database for predictive materials Design. Crystal Growth and Design 24(17), pp. 6911-6930. (10.1021/acs.cgd.4c00694)
- Hatcher, L. E. and Raithby, P. R. 2024. Dynamic crystal structure of a molecular framework. Nature Chemistry 16, pp. 674-675. (10.1038/s41557-024-01514-z)
- Morris, J. J. et al. 2024. Exploring pyroelectricity, thermal and photochemical switching in a hybrid organic-inorganic crystal by in situ X-ray diffraction. Angewandte Chemie International Edition 63(20), article number: e202401552. (10.1002/anie.202401552)
- Bryant, M. J., Fuertes, S., Hatcher, L. E., Thomas, L. H. and Raithby, P. R. 2023. Structural modifications to platinum(ii) pincer complexes resulting in changes in their vapochromic and solvatochromic properties. Faraday Discussions 244, pp. 411-433. (10.1039/d3fd00025g)
- Hatcher, L. E., Saunders, L. K. and Coulson, B. A. 2022. Uncovering the role of non-covalent interactions in solid-state photoswitches by non-spherical structure refinements with NoSpherA2. Faraday Discussions (10.1039/d2fd00158f)
- Hatcher, L. E. et al. 2022. LED-pump-X-ray-multiprobe crystallography for sub-second timescales. Communications Chemistry 5(1), article number: 102. (10.1038/s42004-022-00716-1)
- Coulson, B. A. and Hatcher, L. E. 2022. Exploring the influence of polymorphism and chromophore co-ligands on linkage isomer photoswitching in [Pd(bpy4dca)(NO2)2]. CrystEngComm 24(20), pp. 3701-3714. (10.1039/D2CE00213B)
- Hatcher, L. E., Burgess, A. J., Payne, P. and Wilson, C. C. 2020. From structure to crystallisation and pharmaceutical manufacturing: the CSD in CMAC Workflows. CrystEngComm 22, pp. 7475-7489. (10.1039/D0CE00898B)
- Hatcher, L. E., Li, W., Payne, P., Benyahia, B., Rielly, C. D. and Wilson, C. C. 2020. Tuning morphology in active pharmaceutical ingredients: controlling the crystal habit of lovastatin through solvent choice and non-size-matched polymer additives. Crystal Growth and Design 20(9), pp. 5854-5862. (10.1021/acs.cgd.0c00470)
- Kaminski, R. et al. 2020. Instrument-model refinement in normalized reciprocal-vector space for X-ray Laue diffraction. Journal of Applied Crystallography 53(5), pp. 1370-1375. (10.1107/S1600576720011929)
- Charles, B. et al. 2020. Phase behavior and substitution limit of mixed cesium-formamidinium lead triiodide perovskites. Chemistry of Materials 32(6), pp. 2282-2291. (10.1021/acs.chemmater.9b04032)
- Saunders, L. K. et al. 2019. Exploring short strong hydrogen bonds engineered in organic acid molecular crystals for temperature dependent proton migration behaviour using single crystal synchrotron X-ray diffraction (SCSXRD). CrystEngComm 21(35) (10.1039/C9CE00925F)
- Turner, T. D., Hatcher, L. E., Wilson, C. C. and Roberts, K. J. 2019. Habit modification of the active pharmaceutical ingredient lovastatin through a predictive solvent selection approach. Journal of Pharmaceutical Sciences 108(5) (10.1016/j.xphs.2018.12.012)
- Hatcher, L. E., Skelton, J. M., Warren, M. R. and Raithby, P. R. 2019. Photocrystallographic studies on transition metal nitrito metastable linkage isomers: manipulating the metastable state. Accounts of Chemical Research 52(4) (10.1021/acs.accounts.9b00018)
- Hatcher, L. E. 2018. Understanding solid-state photoswitching in [ReIJOMe2-bpy)IJCO)3IJη1-NO2)] crystals via in situ photocrystallography. CrystEngComm 20(39), article number: 5990. (10.1039/C8CE00774H)
- Saunders, L. K. et al. 2018. Tuning charge-assisted and weak hydrogen bonds in molecular complexes of the proton sponge DMAN by acid co-former substitution. CrystEngComm 20(22) (10.1039/C8CE00443A)
- Gee, W. J., Hatcher, L. E., Cameron, C. A., Stubbs, C., Warren, M. R., Burrows, A. D. and Raithby, P. R. 2018. Evaluating iodine uptake in a crystalline sponge using dynamic X-ray crystallography. Inorganic Chemistry 57(9), pp. 4959-4965. (10.1021/acs.inorgchem.7b03218)
- Henderson, J. et al. 2018. New polymorphs of perylene: tetracyanoquinodimethane charge transfer cocrystals. Crystal Growth and Design 18(4), pp. 2003-2009. (10.1021/acs.cgd.7b01391)
- Hatcher, L. E., Skelton, J. M., Warren, M. R., Stubbs, C., da Silva, E. L. and Raithby, P. R. 2018. Monitoring photo-induced population dynamics in metastable linkage isomer crystals: a crystallographic kinetic study of [Pd(Bu4dien)NO2]BPh4. Physical Chemistry Chemical Physics 20(8) (10.1039/C7CP05422J)
- Bryant, M. J. et al. 2017. A rapidly-reversible absorptive and emissive vapochromic Pt(II) pincer-based chemical sensor. Nature Communications 8, article number: 1800. (10.1038/s41467-017-01941-2)
- Hatcher, L. E. and Raithby, P. R. 2017. The impact of hydrogen bonding on 100% photo-switching in solid-state nitro-nitrito linkage isomers. CrystEngComm 19(42) (10.1039/C7CE01366C)
- Hendon, C. H. et al. 2016. Magnetic coupling in a hybrid Mn(ii) acetylene dicarboxylate. Physical Chemistry Chemical Physics 18(48) (10.1039/C6CP06886C)
- Woodall, C. H. et al. 2016. Observation of a re-entrant phase transition in the molecular complex tris(μ2-3,5-diisopropyl-1,2,4-triazolato-κ2N1:N2)trigold(I) under high pressure. IUCrJ 3(5), pp. 376. (10.1107/S2052252516013129)
- Hatcher, L. E. 2016. Raising the (metastable) bar: 100% photo-switching in [Pd(Bu4dien)(η1-O2)]+ approaches ambient temperature. CrystEngComm 18(22), pp. 4180-4187. (10.1039/C5CE02434J)
- Murray, A. T. et al. 2016. Modelling flavoenzymatic charge transfer events: development of catalytic indole deuteration strategies. Organic and Biomolecular Chemistry 14(15), pp. 3787-3792. (10.1039/C6OB00361C)
- Shepherd, H. et al. 2016. A high pressure investigation of the order-disorder phase transition and accompanying spin crossover in [FeL12](ClO4)2 (L1 = 2,6-bis{3-methylpyrazol-1-yl}-pyrazine). Magnetochemistry 2(1), pp. -., article number: 9. (10.3390/magnetochemistry2010009)
- Skelton, J. M., Lora da Silva, E., Crespo-Otero, R., Hatcher, L. E., Raithby, P. R., Parker, S. C. and Walsh, A. 2015. Electronic excitations in molecular solids: bridging theory and experiment. Faraday Discussions 177 (10.1039/C4FD00168K)
- Skelton, J. M., Crespo-Otero, R., Hatcher, L. E., Parker, S. C., Raithby, P. R. and Walsh, A. 2015. Energetics, thermal isomerisation and photochemistry of the linkage-isomer system [Ni(Et4dien)(η2-O,ON)(η1-NO2)]. CrystEngComm 17(2) (10.1039/C4CE01411A)
- Woodall, C. H. et al. 2014. Tunable trimers: using temperature and pressure to control luminescent emission in gold(I) pyrazolate-based trimers. Chemistry - A European Journal 20(51), pp. 16933-16942. (10.1002/chem.201404058)
- Hatcher, L. E. and Raithby, P. R. 2014. Dynamic single-crystal diffraction studies using synchrotron radiation. Coordination Chemistry Reviews 277-27, pp. 69-79. (10.1016/j.ccr.2014.02.021)
- Hatcher, L. E. et al. 2014. Thermal and photochemical control of nitro-nitrito linkage isomerism in single-crystals of [Ni(medpt)(NO2)(η2-ONO]. CrystEngComm 16(35) (10.1039/C4CE00675E)
- Hatcher, L. E. et al. 2014. Steady‐state and pseudo‐steady‐state photocrystallographic studies on linkageiIsomers of [Ni(Et4dien)(η2‐O,ON)(η1‐NO2)]: identification of a new linkage isomer. Chemistry - A European Journal 20(11), pp. 3128-3134. (10.1002/chem.201304172)
- Hatcher, L. E. and Raithby, P. R. 2013. Solid-state photochemistry of molecular photo-switchable species: the role of photocrystallographic techniques. Acta Crystallographica Section C: Crystal Structure Communications 69(12) (10.1107/S010827011303223X)
- Woodall, C. H. et al. 2013. Hingeless negative linear compression in the mechanochromic gold complex [(C6F5Au)2(μ‐1,4‐diisocyanobenzene)]. Angewandte Chemie International Edition 52(37) (10.1002/anie.201302825)
- Jarvis, A. G. et al. 2012. Photochemical-mediated solid-state [2+2]-cycloaddition reactions of an unsymmetrical dibenzylidene acetone (monothiophos-dba). CrystEngComm 14(17) (10.1039/c2ce25480h)
- Warren, M. R. et al. 2012. Photoactivated linkage isomerism in single crystals of nickel, palladium and platinum di-nitro complexes – a photocrystallographic investigation. Dalton Transactions 41(42) (10.1039/c2dt30314k)
- Bajwa, S. E. et al. 2012. On the appearance of nitrite anion in [PdX(OAc)L2] and [Pd(X)(C^N)L] syntheses (X = OAc or NO2): photocrystallographic identification of metastable Pd(η1-ONO)(C^N)PPh3. Chemical Science 3(5) (10.1039/c2sc01050j)
- Hatcher, L. E. et al. 2011. Metastable linkage isomerism in [Ni(Et4dien)(NO2)2]: a combined thermal and photocrystallographic structural investigation of a Nitro/Nitrito interconversion. Angewandte Chemie International Edition 50(36), pp. 8371-8374. (10.1002/anie.201102022)
Ymchwil
Diddordebau Ymchwil:
Rwy'n gemegydd organometalig solet-wladwriaeth gydag arbenigedd arbennig mewn diffreithiant pelydr-X crisial sengl wedi'i ddatrys mewn amser, ffotocrystallography a pheirianneg grisial deunyddiau moleciwlaidd a fframwaith y gellir eu newid.
Mae strwythur deunydd yn dal yr allwedd i ddeall ei briodweddau defnyddiol a dyma pam rwyf wedi fy swyno gan gemeg cyflwr cadarn. Mae diffreithiant pelydr-X grisial sengl yn darparu gwybodaeth gywir iawn am strwythur deunyddiau crisialog ac fe'i defnyddir i ail-greu delwedd 3D o'r atomau a'r moleciwlau unigol. Trwy gyfuno'r technegau hyn â excitation yn y fan a'r lle (ee meysydd ysgafn, tymheredd, pwysau a thrydan) a methodolegau wedi'u datrys ag amser, rwy'n anelu at greu "ffilmiau moleciwlaidd" sy'n dangos sut mae deunyddiau y gellir eu newid yn ymateb i gyffro mewn 3D ac mewn amser real.
Prosiectau Ymchwil:
Diffraction pelydr-X deinamig mewn Dylunio Deunyddiau Ynni Solar (Cymrodoriaeth Ymchwil Prifysgol y Gymdeithas Frenhinol).
Mae fy mhrosiect URF cyfredol, Dynamic X-ray Diffraction mewn Dylunio Deunyddiau Ynni Solar, yn datblygu deunyddiau ferroelectric ffoto-weithredol newydd ac yn pennu'r sail strwythurol ar gyfer eu swyddogaeth a achosir gan olau gan ddefnyddio technegau ffotocrystallograffig mewnol. Gall deunyddiau ferroelectric ffoto-weithredol drosi golau haul yn drydan yn uniongyrchol ac maent yn ddymunol iawn ar gyfer cymwysiadau ynni solar. Drwy ddatblygu dulliau diffreithiant pelydr-X deinamig blaengar, yng Nghaerdydd ac mewn cydweithrediad â Diamond Light Source, byddwn yn gwylio sut mae'r deunyddiau hyn yn rhyngweithio â golau mewn amser real. Yna bydd y ddealltwriaeth well hon yn cael ei chymryd yn ôl i'r labordy synthetig a'i ddefnyddio i ddylunio crisialau newydd gyda galluoedd ferroelectric gwell a achosir gan ffoto. Mae gan yr ymchwil hon y potensial cyffrous i gyflawni effaith fyd-eang go iawn trwy chwyldroi ein dealltwriaeth o drawsnewid ynni solar ar y raddfa atomig, a all yn ei dro arwain at ddylunio celloedd solar newydd a mwy effeithlon.
Microcrystallization Uwch ar gyfer Crystallography Cyfresol
Mae'r prosiect hwn yn rhedeg mewn cydweithrediad â synchrotron y DU, Diamond Light Source.
Mae crisialograffeg pelydr-X traddodiadol yn cynnwys casglu set ddata strwythur grisial 3D gyflawn o un grisial sengl, berffaith i raddau helaeth. Mae gan hyn lawer o fanteision, ond mewn sefyllfaoedd nid yw'r crisialau yn sefydlog trwy gydol yr arbrawf pelydr-X a / neu gael difrod oherwydd amlygiad i belydrau-X egni uchel neu arbelydru ysgafn, yna nid yw'n bosibl casglu'r holl ddata sy'n ofynnol o'r un sampl grisial yn unig. Yn lle hynny, mae dulliau casglu data aml-grisial fel crisialograffeg cyfresol bellach yn cael eu datblygu, lle ceir pob delwedd ddata o grisial wahanol ac yna cyfunir y delweddau hyn yn ddiweddarach i gynhyrchu'r set ddata gyflawn. Mae yna lawer o heriau a gyflwynir gan arbrofion crisialograffi cyfresol, sy'n cael sylw yn y prosiect hwn. Yn fwyaf arbennig, yng Nghaerdydd rydym yn gweithio i ddatblygu strategaethau crisialu wedi'u targedu newydd i gynhyrchu'r cannoedd, neu weithiau miloedd, o grisialau sengl perffaith sy'n ofynnol ar gyfer yr arbrofion hyn. Mae'r arbrofion hyn yn optimeiddio'r dosbarthiad maint grisial a'r arfer grisial, gan anelu at y swp mwyaf cyson, unffurf o ficrocrystals sy'n bosibl ar draws y swp.
I gael rhagor o wybodaeth am brosiectau penodol sydd ar gael gyda Dr Lauren Hatcher, adolygwch adran Deunyddiau ac Ynni ein themâu prosiect ymchwil.
Bywgraffiad
Dr Lauren E. Hatcher is a Royal Society University Research Fellow (Mar 2020 – present) in the School of Chemistry at Cardiff University. Prior to this she worked as a Research Associate in the Department of Chemistry at the University of Bath (RA in Crystallisation Science for Manufacturing (CMAC), Jan 2018 – Jan 2020; RA in the Metastable Materials Research Group, Jan 2014 – Jan 2018). Lauren completed her PhD in Chemistry at the University of Bath in May 2014, under the supervision of Prof. Paul Raithby (Thesis title: Molecular Photocrystallography). She also completed her undergraduate studies at Bath in 2010 (1:1 BSc(Hons) in Natural Sciences with Industrial Placement) and as part of this course spent one year as an Industrial Placement Student in the Small Molecule Crystallography Group at GlaxoSmithKline Services, Harlow.
Anrhydeddau a dyfarniadau
- Royal Society University Research Fellowship (2019)
- CCDC Chemical Crystallography Prize for Younger Scientists, British Crystallographic Association (2017)
- American Crystallographic Association travel grant, American Crystallographic Association meeting, Denver (2016)
- Rigaku travel grant, British Crystallographic Association Spring Meeting, Lancaster (2015)
- Journal of Chemical Crystallography poster prize, 63rd American Crystallographic Association meeting, Hawaii (2013)
- Final Year Postgraduate Symposium Prize (Bolland Symposium), University of Bath Department of Chemistry (2013)
- Oxford Cryosystems Low Temperature poster prize, 22nd International Union of Crystallography Congress, Madrid (2011)
- Magaret Etter Student Lecturer Award, 61st American Crystallography Meeting, New Orleans (2011)
- The Leadership Forum Award for Best Chemistry Student, European SET Student of the Year Awards (2010)
- Faculty of Science Prize for Best Natural Sciences Student, University of Bath (2007, 2008, 2010)
Aelodaethau proffesiynol
- Member of the British Crystallographic Association
- Member of the Royal Society of Chemistry
Safleoedd academaidd blaenorol
- Jan 2018 - Jan 2020: Research Associate in Crystallisation Science for Manufacturing (CMAC), EPSRC grant EP/I033459/1, Department of Chemistry, University of Bath
- Jan 2014 - Jan 2018: Research Associate, Metastable Materials Group, EPSRC grant EP/K004956/1 Department of Chemistry, University of Bath
- Feb 2016 - Oct 2016: Impact Acceleration Fellow (secondment), EPSRC grant EP/I01974X/1, Research Complex at Harwell, Rutherford Appleton Laboratory, Didcot
Pwyllgorau ac adolygu
- BCA Chemical Crystallography Group, Vice-Chair (2018 - 2019)
- BCA Chemical Crystallography Group, Ordinary member (2016 - 2018)
- BCA Young Crystallographers Group, Secretary/Treasurer (2012 - 2014)
Meysydd goruchwyliaeth
As our research group specialises in the design of useful switchable materials and understanding the structure-property correlations that are responsible for their functionality, I am highly interested in supervising students with interests in several areas of chemistry, including:
- structural chemistry and crystallography
- analytical chemistry
- synthetic organometallic and inorganic chemistry
- advanced crystallisation techniques.
Goruchwyliaeth gyfredol
Sam Lewis
Myfyriwr ymchwil
Debashish Das
Myfyriwr ymchwil
Josh Morris
Myfyriwr ymchwil
Contact Details
+44 29225 11783
Y Prif Adeilad, Ystafell Room 2.82, Plas y Parc, Caerdydd, CF10 3AT