![Imran Mohammed BPharm., MSc., PhD., FHEA](https://profiles-cardiff.imgix.net/attachments/2821?w=200&h=200&auto=format&crop=faces&fit=crop&q=90")
Dr Imran Mohammed
BPharm., MSc., PhD., FHEA
- Ar gael fel goruchwyliwr ôl-raddedig
Timau a rolau for Imran Mohammed
Darlithydd (Athro Cynorthwyol)
Cynullydd Asesu ac Arweinydd Cydraddoldeb, Amrywiaeth, Cynhwysiant a Gwrth-Hiliaeth
Trosolwyg
Ar hyn o bryd rwy'n Ddarlithydd (Athro Cynorthwyol) ac yn Arweinydd Grŵp Darganfod Cyffuriau Gwrthficrobaidd yn yr Ysgol Optometreg a Gwyddorau Gweledigaeth, Coleg y Gwyddorau Biofeddygol a Bywyd.
Keratitis microbaidd (a elwir hefyd yn keratitis heintus) yw prif achos dallineb monocwlaidd ledled y byd. Prif ffocws fy labordy yw ymchwilio i'r rhyngweithiadau gwesteiwr-pathogen yn ystod haint cornbilen a datblygu therapiwteg imiwnomodulatory a gwrth-heintus newydd ar gyfer atal dallineb.
Mae gen i dros 15 mlynedd o brofiad ymchwil academaidd mewn datblygiad cyn-glinigol therapiwteg newydd ar gyfer dallineb cornbilen a retinal.
Rwyf wedi cyhoeddi >40 o erthyglau ymchwil mewn cyfnodolion gwyddonol, wedi denu >£875,000 o gyllid ymchwil, wedi derbyn nifer o wobrau a gwobrau, wedi cael fy ngwahodd fel prif siaradwr mewn nifer o gynadleddau/cyfarfodydd, a datblygu deunyddiau eiddo deallusol.
Cyhoeddiad
2026
- Barahim, E. K. et al., 2026. Evaluation of antimicrobial peptide–antibiotic combination treatment for tackling ocular and systemic staphylococcus aureus infections. International Journal of Molecular Sciences 27 (12) 5573. (10.3390/ijms27125573)
2024
- Hammoudeh, Y. et al., 2024. Microbiological culture versus 16S/18S rRNA gene PCR-sanger sequencing for infectious keratitis: a three-arm, diagnostic cross-sectional study. Frontiers in Medicine 11 1393832. (10.3389/fmed.2024.1393832)
2023
- Dua, H. S. et al., 2023. An approach to reduce Descemet's membrane scrolling: Relevance to Descemet's membrane endothelial keratoplasty (DMEK). Indian Journal of Ophthalmology 71 (9), pp.3178-3185. (10.4103/IJO.IJO_1531_23)
2022
- Deshmukh, R. et al., 2022. Real-world experience of using ciclosporin-A 0.1% in the management of ocular surface inflammatory diseases. British Journal of Ophthalmology 106 , pp.1087-1092. (10.1136/bjophthalmol-2020-317907)
- Ting, D. et al., 2022. Host defense peptides at the ocular surface: roles in health and major diseases, and therapeutic potentials.. Frontiers in Medicine 9 835843. (10.3389/fmed.2022.835843)
- Ali, W. et al., 2022. Host defence peptides: a potent alternative to combat antimicrobial resistance in the era of the covid-19 pandemic.. Antibiotics (Basel, Switzerland) 11 (4) 475. (10.3390/antibiotics11040475)
2021
- Shu Jeng Ting, D. et al., 2021. Evaluation of host defense peptide (CaD23)-antibiotic interaction and mechanism of action: insights from experimental and molecular dynamics simulations studies. Frontiers in Pharmacology 12 731499. (10.3389/fphar.2021.731499)
- Shu Jeng Ting, D. et al., 2021. Hybrid derivative of cathelicidin and human beta defensin-2 against Gram-positive bacteria: A novel approach for the treatment of bacterial keratitis. Scientific Reports 11 18304. (10.1038/s41598-021-97821-3)
- Akhtar, R. et al., 2021. Toll-like receptor signalling pathways regulate hypoxic stress induced fibroblast growth factor but not vascular endothelial growth factor-a in human microvascular endothelial cells. International Journal of Translational Medicine 1 (1), pp.25-38. (10.3390/ijtm1010003)
2020
- Mohammed, I. et al. 2020. Profiling ocular surface responses to preserved and non-preserved topical glaucoma medications: a two-year randomised evaluation study. Clinical & experimental ophthalmology 48 (7), pp.973-982. (10.1111/ceo.13814)
- Mohammed, I. et al. 2020. Antimicrobial peptides in human corneal tissue of patients with fungal keratitis. British Journal of Ophthalmology 105 , pp.1172-1177. (10.1136/bjophthalmol-2020-316329)
- Ting, D. S. J. et al., 2020. Strategies in translating the therapeutic potentials of host defense peptides. Frontiers in Immunology 11 983. (10.3389/fimmu.2020.00983)
2019
- Al-Aqaba, M. A. et al., 2019. Corneal nerves in health and disease. Progress in Retinal and Eye Research 73 100762. (10.1016/j.preteyeres.2019.05.003)
- Mohammed, I. et al. 2019. Cathelicidin-derived synthetic peptide improves therapeutic potential of vancomycin against pseudomonas aeruginosa. Frontiers in Microbiology 10 2190. (10.3389/fmicb.2019.02190)
- Al-Aqaba, M. A. et al., 2019. In vivo confocal microscopy features and clinicohistological correlation of limbal nerve corpuscles. British Journal of Ophthalmology 105 , pp.285-289. (10.1136/bjophthalmol-2018-313199)
- Ghoz, N. et al., 2019. Management of primary pterygium with intra-lesional injection of 5 flurouracil and bevacizumab (Avastin).. Eye 33 , pp.1776-1783. (10.1038/s41433-019-0493-0)
- Song, D. et al., 2019. Complement factor h mutation w1206r causes retinal thrombosis and ischemic retinopathy in mice. The American Journal of Pathology 189 (4), pp.826-838. (10.1016/j.ajpath.2019.01.009)
2018
- Said, D. G. et al., 2018. Localised corneal haze and scarring following pulsed accelerated collagen cross-linking for keratoconus. Eye (Basingstoke) 33 (1), pp.167-168. (10.1038/s41433-018-0211-3)
- Song, D. et al., 2018. Retinal basal laminar deposits in complement fh/fp mouse model of dense deposit disease. Investigative Ophthalmology & Visual Science 54 , pp.3405-3415. (10.1167/iovs.18-24133)
- Mohammed, I. et al. 2018. Elastin content and distribution in endothelial keratoplasty tissue determines direction of scrolling. American Journal of Ophthalmology 194 , pp.16-25. (10.1016/j.ajo.2018.07.001)
2017
- Al-Aqaba, M. .. et al., 2017. Nerve terminals at the human corneoscleral limbus. British Journal of Ophthalmology 102 (4), pp.556-561. (10.1136/bjophthalmol-2017-311146)
- Mohammed, I. , Said, D. G. and Dua, H. S. 2017. Human antimicrobial peptides in ocular surface defense. Progress in Retinal and Eye Research 61 , pp.1-22. (10.1016/j.preteyeres.2017.03.004)
- Ueda, Y. et al., 2017. Murine systemic thrombophilia and hemolytic uremic syndrome from a factor h point mutation. Blood 129 (9), pp.1184-1196. (10.1182/blood-2016-07-728253)
2014
- Haris, M. et al., 2014. In vivo magnetic resonance imaging of tumor protease activity. Scientific Reports 4 6081. (10.1038/srep06081)
- Dua, H. S. et al., 2014. In vitro studies on the antimicrobial peptide human beta-defensin 9 (HBD9): signalling pathways and pathogen-related response (an American Ophthalmological Society thesis).. Transactions of the American Ophthalmological Society 112 , pp.50-73.
2013
- Barata, L. et al., 2013. Deletion of crry and DAF on murine platelets stimulates thrombopoiesis and increases factor H-dependent resistance of peripheral platelets to complement attack. The Journal of Immunology 190 (6), pp.2886-2895. (10.4049/jimmunol.1202536)
2012
- Otri, A. M. et al., 2012. Variable expression of human beta defensins 3 and 9 at the human ocular surface in infectious keratitis. Investigative Ophthalmology and Visual Science 53 (2), pp.757-761. (10.1167/iovs.11-8467)
2011
- Mohammed, I. et al. 2011. Increased expression of hepcidin and toll-like receptors 8 and 10 in viral keratitis. Cornea 30 (8), pp.899-904. (10.1097/ICO.0b013e31820126e5)
- Kulkarni, B. et al., 2011. Validation of endogenous control genes for gene expression studies on human ocular surface epithelium. PLoS ONE 6 (8) 22301. (10.1371/journal.pone.0022301)
- Mohammed, I. et al. 2011. Signalling pathways involved in ribonuclease-7 expression. Cellular and Molecular Life Sciences 68 (11), pp.1941-1952. (10.1007/s00018-010-0540-2)
2010
- Mohammed, I. et al. 2010. Localization and gene expression of human β-defensin 9 at the human ocular surface epithelium. Investigative Ophthalmology and Visual Science 51 (9), pp.4677-4682. (10.1167/iovs.10-5334)
- Kulkarni, B. B. et al., 2010. Comparative transcriptional profiling of the limbal epithelial crypt demonstrates its putative stem cell niche characteristics. BMC Genomics 11 (1) 526. (10.1186/1471-2164-11-526)
- Otri, A. M. et al., 2010. Antimicrobial peptides expression by ocular surface cells in response to acanthamoeba castellanii: an in vitro study. British Journal of Ophthalmology 94 (11), pp.1523-1527. (10.1136/bjo.2009.178236)
2009
- Gicquel, J. et al., 2009. Epidermal growth factor variations in amniotic membrane used for ex vivo tissue constructs. Tissue Engineering - Part A 15 (8), pp.1919-1927. (10.1089/ten.tea.2008.0432)
- Yeung, A. et al., 2009. Infant limbus: an immunohistological study. Experimental Eye Research 88 (6), pp.1161-1164. (10.1016/j.exer.2008.12.014)
2008
- Abedin, A. et al., 2008. A novel antimicrobial peptide on the ocular surface shows decreased expression in inflammation and infection. Investigative Ophthalmology and Visual Science 49 (1), pp.28-33. (10.1167/iovs.07-0645)
Articles
- Barahim, E. K. et al., 2026. Evaluation of antimicrobial peptide–antibiotic combination treatment for tackling ocular and systemic staphylococcus aureus infections. International Journal of Molecular Sciences 27 (12) 5573. (10.3390/ijms27125573)
- Hammoudeh, Y. et al., 2024. Microbiological culture versus 16S/18S rRNA gene PCR-sanger sequencing for infectious keratitis: a three-arm, diagnostic cross-sectional study. Frontiers in Medicine 11 1393832. (10.3389/fmed.2024.1393832)
- Dua, H. S. et al., 2023. An approach to reduce Descemet's membrane scrolling: Relevance to Descemet's membrane endothelial keratoplasty (DMEK). Indian Journal of Ophthalmology 71 (9), pp.3178-3185. (10.4103/IJO.IJO_1531_23)
- Deshmukh, R. et al., 2022. Real-world experience of using ciclosporin-A 0.1% in the management of ocular surface inflammatory diseases. British Journal of Ophthalmology 106 , pp.1087-1092. (10.1136/bjophthalmol-2020-317907)
- Ting, D. et al., 2022. Host defense peptides at the ocular surface: roles in health and major diseases, and therapeutic potentials.. Frontiers in Medicine 9 835843. (10.3389/fmed.2022.835843)
- Ali, W. et al., 2022. Host defence peptides: a potent alternative to combat antimicrobial resistance in the era of the covid-19 pandemic.. Antibiotics (Basel, Switzerland) 11 (4) 475. (10.3390/antibiotics11040475)
- Shu Jeng Ting, D. et al., 2021. Evaluation of host defense peptide (CaD23)-antibiotic interaction and mechanism of action: insights from experimental and molecular dynamics simulations studies. Frontiers in Pharmacology 12 731499. (10.3389/fphar.2021.731499)
- Shu Jeng Ting, D. et al., 2021. Hybrid derivative of cathelicidin and human beta defensin-2 against Gram-positive bacteria: A novel approach for the treatment of bacterial keratitis. Scientific Reports 11 18304. (10.1038/s41598-021-97821-3)
- Akhtar, R. et al., 2021. Toll-like receptor signalling pathways regulate hypoxic stress induced fibroblast growth factor but not vascular endothelial growth factor-a in human microvascular endothelial cells. International Journal of Translational Medicine 1 (1), pp.25-38. (10.3390/ijtm1010003)
- Mohammed, I. et al. 2020. Profiling ocular surface responses to preserved and non-preserved topical glaucoma medications: a two-year randomised evaluation study. Clinical & experimental ophthalmology 48 (7), pp.973-982. (10.1111/ceo.13814)
- Mohammed, I. et al. 2020. Antimicrobial peptides in human corneal tissue of patients with fungal keratitis. British Journal of Ophthalmology 105 , pp.1172-1177. (10.1136/bjophthalmol-2020-316329)
- Ting, D. S. J. et al., 2020. Strategies in translating the therapeutic potentials of host defense peptides. Frontiers in Immunology 11 983. (10.3389/fimmu.2020.00983)
- Al-Aqaba, M. A. et al., 2019. Corneal nerves in health and disease. Progress in Retinal and Eye Research 73 100762. (10.1016/j.preteyeres.2019.05.003)
- Mohammed, I. et al. 2019. Cathelicidin-derived synthetic peptide improves therapeutic potential of vancomycin against pseudomonas aeruginosa. Frontiers in Microbiology 10 2190. (10.3389/fmicb.2019.02190)
- Al-Aqaba, M. A. et al., 2019. In vivo confocal microscopy features and clinicohistological correlation of limbal nerve corpuscles. British Journal of Ophthalmology 105 , pp.285-289. (10.1136/bjophthalmol-2018-313199)
- Ghoz, N. et al., 2019. Management of primary pterygium with intra-lesional injection of 5 flurouracil and bevacizumab (Avastin).. Eye 33 , pp.1776-1783. (10.1038/s41433-019-0493-0)
- Song, D. et al., 2019. Complement factor h mutation w1206r causes retinal thrombosis and ischemic retinopathy in mice. The American Journal of Pathology 189 (4), pp.826-838. (10.1016/j.ajpath.2019.01.009)
- Said, D. G. et al., 2018. Localised corneal haze and scarring following pulsed accelerated collagen cross-linking for keratoconus. Eye (Basingstoke) 33 (1), pp.167-168. (10.1038/s41433-018-0211-3)
- Song, D. et al., 2018. Retinal basal laminar deposits in complement fh/fp mouse model of dense deposit disease. Investigative Ophthalmology & Visual Science 54 , pp.3405-3415. (10.1167/iovs.18-24133)
- Mohammed, I. et al. 2018. Elastin content and distribution in endothelial keratoplasty tissue determines direction of scrolling. American Journal of Ophthalmology 194 , pp.16-25. (10.1016/j.ajo.2018.07.001)
- Al-Aqaba, M. .. et al., 2017. Nerve terminals at the human corneoscleral limbus. British Journal of Ophthalmology 102 (4), pp.556-561. (10.1136/bjophthalmol-2017-311146)
- Mohammed, I. , Said, D. G. and Dua, H. S. 2017. Human antimicrobial peptides in ocular surface defense. Progress in Retinal and Eye Research 61 , pp.1-22. (10.1016/j.preteyeres.2017.03.004)
- Ueda, Y. et al., 2017. Murine systemic thrombophilia and hemolytic uremic syndrome from a factor h point mutation. Blood 129 (9), pp.1184-1196. (10.1182/blood-2016-07-728253)
- Haris, M. et al., 2014. In vivo magnetic resonance imaging of tumor protease activity. Scientific Reports 4 6081. (10.1038/srep06081)
- Dua, H. S. et al., 2014. In vitro studies on the antimicrobial peptide human beta-defensin 9 (HBD9): signalling pathways and pathogen-related response (an American Ophthalmological Society thesis).. Transactions of the American Ophthalmological Society 112 , pp.50-73.
- Barata, L. et al., 2013. Deletion of crry and DAF on murine platelets stimulates thrombopoiesis and increases factor H-dependent resistance of peripheral platelets to complement attack. The Journal of Immunology 190 (6), pp.2886-2895. (10.4049/jimmunol.1202536)
- Otri, A. M. et al., 2012. Variable expression of human beta defensins 3 and 9 at the human ocular surface in infectious keratitis. Investigative Ophthalmology and Visual Science 53 (2), pp.757-761. (10.1167/iovs.11-8467)
- Mohammed, I. et al. 2011. Increased expression of hepcidin and toll-like receptors 8 and 10 in viral keratitis. Cornea 30 (8), pp.899-904. (10.1097/ICO.0b013e31820126e5)
- Kulkarni, B. et al., 2011. Validation of endogenous control genes for gene expression studies on human ocular surface epithelium. PLoS ONE 6 (8) 22301. (10.1371/journal.pone.0022301)
- Mohammed, I. et al. 2011. Signalling pathways involved in ribonuclease-7 expression. Cellular and Molecular Life Sciences 68 (11), pp.1941-1952. (10.1007/s00018-010-0540-2)
- Mohammed, I. et al. 2010. Localization and gene expression of human β-defensin 9 at the human ocular surface epithelium. Investigative Ophthalmology and Visual Science 51 (9), pp.4677-4682. (10.1167/iovs.10-5334)
- Kulkarni, B. B. et al., 2010. Comparative transcriptional profiling of the limbal epithelial crypt demonstrates its putative stem cell niche characteristics. BMC Genomics 11 (1) 526. (10.1186/1471-2164-11-526)
- Otri, A. M. et al., 2010. Antimicrobial peptides expression by ocular surface cells in response to acanthamoeba castellanii: an in vitro study. British Journal of Ophthalmology 94 (11), pp.1523-1527. (10.1136/bjo.2009.178236)
- Gicquel, J. et al., 2009. Epidermal growth factor variations in amniotic membrane used for ex vivo tissue constructs. Tissue Engineering - Part A 15 (8), pp.1919-1927. (10.1089/ten.tea.2008.0432)
- Yeung, A. et al., 2009. Infant limbus: an immunohistological study. Experimental Eye Research 88 (6), pp.1161-1164. (10.1016/j.exer.2008.12.014)
- Abedin, A. et al., 2008. A novel antimicrobial peptide on the ocular surface shows decreased expression in inflammation and infection. Investigative Ophthalmology and Visual Science 49 (1), pp.28-33. (10.1167/iovs.07-0645)
Ymchwil
Prif ffocws fy labordy yw astudio'r rhyngweithiadau host-pathogen yn ystod haint cornbilen, yn enwedig ymchwilio i'r pathobioleg sy'n deillio o ryngweithio celloedd imiwnedd â bioffilmiau bacteriol yn y gornbilen. Yn ogystal, ein nod yw ymchwilio i effeithiolrwydd ffarmacolegol a diogelwch peptidau gwrth-amddiffyn gwesteiwr synthetig fel therapi amgen ar gyfer trin haint cornbilen.
Rydym yn defnyddio model llygoden preclinical o haint cornbilen ar gyfer astudio'r rhyngweithiadau host-pathogen a phrofi therapiwteg newydd. Hefyd, mae systemau model in-vitro, ex-vivo, ac in-silico priodol wedi'u sefydlu'n dda ar gyfer astudiaethau sgrinio ac effeithiolrwydd diogelwch cychwynnol.
Potensial ar gyfer cydweithio a chynnal cymrodoriaethau:
Mae fy labordy ar agor ar gyfer cydweithrediadau academaidd/diwydiannol ac yn cynnal cymrodoriaethau ôl-ddoethurol / PhD posibl yn y meysydd ymchwil canlynol:
- Asiantau gwrth-heintiol: Datblygu a phrofi
- Heintiau Corneal: Torri patholeg clefyd a phrofi therapiwteg newydd
- ymwrthedd gwrthficrobaidd: Eu perthnasedd i ddifrifoldeb afiechydon ac aneffeithiolrwydd therapiwteg sydd ar gael
- Asiantau gwrth-fioffilm: Datblygu a phrofi
- Rhyngweithiadau Host-pathogen: sy'n ymwneud yn bennaf yn ystod keratitis microbaidd a heintiau bioffilm
- Ategu llwybrau actifadu: eu dysregulation a'u cysylltiad â batholegau clefyd cornbilen
- Peptidau Host-amddiffyn: Ailgynllunio, datblygu a phrofi
Cydweithredwyr presennol:
- Miguel Camara - Athro Microbioleg a Chyd-gyfarwyddwr Canolfan Arloesi Bioffilmiau Cenedlaethol (Prifysgol Nottingham)
- Arwyn Jones - Athro Fferylliaeth a Gwyddorau Fferyllol (Prifysgol Caerdydd)
- Polina Porkopovich - Darllenydd Fferylliaeth (Prifysgol Caerdydd)
- Oliver Castell - Darllenydd Fferylliaeth (Prifysgol Caerdydd)
- Luisa-Martinez Pomares - Athro Imiwnoleg (Prifysgol Nottingham)
- Harminder S. Dua - Pennaeth ac Athro Offthalmoleg (Prifysgol Nottingham)
- Winfried M. Amoaku - Athro Cyswllt Offthalmoleg (Prifysgol Nottingham)
- Naing Latt Tint - Offthalmolegydd Ymgynghorol (Prifysgol Caeredin)
- Beth Mills - Cymrawd Arweinydd y Dyfodol UKRI (Prifysgol Caeredin)
- Chandra Verma - Uwch Brif Ymchwilydd (A * Sefydliad Biowybodeg Star, Singapore)
- Rajamani Lakshminarayanan - Pennaeth a Phrif Ymchwilydd (Sefydliad Ymchwil Llygaid Singapore, Singapore)
- Cân Wen-Chao - Athro Ffarmacoleg (Prifysgol Pennsylvania, UDA)
Addysgu
Addysgu Israddedig
| Modiwlau/au | Cwrs a Threfniadaeth | Rôl | unit-format |
| Y Llygad a'r Corff Dynol (OP4005) |
Rhaglen Meistr Optometreg (MOptom) (Blwyddyn ragarweiniol) Ysgol Optometreg a Gwyddorau'r Golwg, Prifysgol Caerdydd, DU |
Arweinydd modiwl a darlithio | 2025 - presennol |
| Gwyddoniaeth Biolegol ar gyfer Optometreg (OP4002) |
Rhaglen Meistr Optometreg (MOptom) (Blwyddyn ragarweiniol) Ysgol Optometreg a Gwyddorau'r Golwg, Prifysgol Caerdydd, DU |
Arwain sesiynau ymarferol | 2025 - presennol |
| Patholeg a Rheolaeth (OP2503) |
Rhaglen Meistr Optometreg (MOptom) (Ail flwyddyn) Ysgol Optometreg a Gwyddorau'r Golwg, Prifysgol Caerdydd, DU |
Sesiynau addysgu thematig | 2025 - presennol |
| Ymchwil ac Optometreg sy'n seiliedig ar dystiolaeth (OP3506) |
Rhaglen Meistr Optometreg (MOptom) (Trydedd flwyddyn) Ysgol Optometreg a Gwyddorau'r Golwg, Prifysgol Caerdydd, DU |
Arwain prosiectau ymchwil | 2025 - presennol |
| Y Corff a'r Meddwl Dynol (OP4003) |
Rhaglen Meistr Optometreg (MOptom) (Blwyddyn ragarweiniol) Ysgol Optometreg a Gwyddorau'r Golwg, Prifysgol Caerdydd, DU |
Arweinydd modiwl a darlithio | 2023 - 25 |
| Iechyd a Chlefydau Cleifion (OP4103) |
Rhaglen Meistr Optometreg (MOptom) (blwyddyn 1af) Ysgol Optometreg a Gwyddorau'r Golwg, Prifysgol Caerdydd, DU |
Arwain sesiynau ymarferol | 2023 - 24 |
| Ffarmacoleg Llygaid (OP2205) |
Rhaglen BSc Optometreg a Gwyddorau Gweledigaeth (2il flwyddyn) Ysgol Optometreg a Gwyddorau'r Golwg, Prifysgol Caerdydd, DU |
Cyd-oruchwylio sesiynau ymarferol | 2022 - 25 |
| Ymchwil mewn Optometreg a Gwyddorau Gweledigaeth (OP3207) |
Rhaglen BSc Optometreg a Gwyddorau Gweledigaeth (3ydd flwyddyn) Ysgol Optometreg a Gwyddorau'r Golwg, Prifysgol Caerdydd, DU |
Arwain prosiectau ymchwil | 2022 - 26 |
| Prosiect Ymchwil (OPT063) |
Rhaglen MSc Optometreg (Cyrsiau amser llawn a rhan-amser) Ysgol Optometreg a Gwyddorau'r Golwg, Prifysgol Caerdydd, DU |
Arwain prosiectau ymchwil | 2022 - presennol |
| Astudio gwyddoniaeth a sgiliau (OP0306) |
Rhaglen BSc Optometreg a Gwyddorau Gweledigaeth (blwyddyn 1af) Ysgol Optometreg a Gwyddorau'r Golwg, Prifysgol Caerdydd, DU |
Arweinydd modiwl a darlithio | 2022 - 23 |
| O Gelloedd i Systemau (OP1205) |
Rhaglen BSc Optometreg a Gwyddorau Gweledigaeth (blwyddyn 1af) Ysgol Optometreg a Gwyddorau'r Golwg, Prifysgol Caerdydd, DU |
Cyd-oruchwylio sesiynau ymarferol | 2022 - 23 |
| Cyflwyniad i Niwrowyddorau Synhwyraidd (A13ISN) |
Rhaglen BMedSci / MB BCh (3ydd flwyddyn) Ysgol Meddygaeth, Prifysgol Nottingham, DU |
Darlithoedd dethol bob semester | 2017 - 22 |
|
Imiwnoleg Gyffredinol (PHG 218) Ffarmacoleg Moleciwlaidd (PHG 225) |
Rhaglen PharmD (2il flwyddyn) Coleg Fferylliaeth, Prifysgol Qassim, KSA |
Arweinydd modiwl a darlithio | 2014 - 15 |
Bywgraffiad
Bywgraffiad
Enillodd Imran gymhwyster israddedig mewn Fferylliaeth (B.Pharm., gyda Rhagoriaeth) o Brifysgol Dechnolegol Jawaharlal Nehru, Hyderabad, India. Symudodd i'r DU ar gyfer ôl-raddio ac yn 2005 cwblhaodd M.Sc mewn Ffarmacoleg (gyda dosbarth Teilyngdod) o Brifysgol Sheffield Hallam, lle dysgodd botensial ymchwil biofeddygol ar gyfer darganfod cyffuriau . Roedd ei swydd ymchwil gyntaf fel Cynorthwyydd Ymchwil ym Mhrifysgol Nottingham (UoN) yn llwyddiannus ac arweiniodd ef i ddilyn gyrfa mewn ymchwil feddygol. Yn 2006, dyfarnwyd grant ysgoloriaeth Ph.D. i Imran gan y Fight for Sight (sefydliad elusennol ymchwil llygaid) ar gyfer astudiaethau doethurol yn UoN o dan oruchwyliaeth yr Athro Harminder S. Dua a Dr. Andy Hopkinson. Ym mis Ebrill 2010, dyfarnwyd gradd Ph.D. iddo gyda "Gwobr Ymchwil Ôl-raddedig Andrew Hendry Endowed" mawreddog am ragoriaeth ymchwil. Roedd Imran yn awyddus i ennill sgiliau arbenigol sy'n berthnasol i ddatblygu ac astudio systemau model murine cyn-glinigol o glefydau llygaid, a arweiniodd ef i'r UDA. Cwblhaodd hyfforddiant ôl-ddoethurol (2010 i 2014) yn labordy yr Athro Wen-Chao Song ym Mhrifysgol Pennsylvania (UPenn), Philadelphia, PA, lle dyfarnwyd "Gwobr Ôl-ddoethurol Biofeddygol" fawreddog iddo am gyflawniadau ymchwil. Rhwng 2014 a 2015, archwiliodd Imran swydd addysgu ym Mhrifysgol Qassim, KSA fel Athro Cynorthwyol Imiwnoleg. Yn ddiweddarach yn 2015, cynigiwyd swydd o'r un enw yn Nottingham i weithio fel uwch wyddonydd Elizabeth C. King . Oherwydd ei lwyddiant parhaus wrth sicrhau cyllid grant a chyhoeddi erthyglau ymchwil effaith uchel, yn 2018, cafodd ei ddyrchafu i swydd Uwch Gymrawd Ymchwil annibynnol . Yn 2022, ymunodd Imran â Phrifysgol Caerdydd fel Darlithydd/Athro Cynorthwyol yn yr Ysgol Optometreg a Gwyddorau Gweledigaeth, lle mae ei labordy yn ymchwilio i imiwnopatholeg haint y gornbilen gyda diddordeb allweddol mewn datblygu peptidau amddiffyn gwesteiwr synthetig fel therapi newydd ar gyfer ei driniaeth.
Cymwysterau Addysgol a Phroffesiynol
| Cymhwyster a Chymrodoriaeth | Mawr | Dyddiadau |
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Cymrawd yr Academi Addysg Uwch (FHEA) Advance HEA a Phrifysgol Caerdydd, y DU |
Addysgu ac Addysg | 03/2026 |
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Doethur mewn Athroniaeth (Ph.D.) Prifysgol Nottingham, DU |
Imiwnoleg Llygaid | 11/2006 – 04/2010 |
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Meistr mewn Gwyddoniaeth (M.Sc.) Prifysgol Sheffield Hallam, DU |
Ffarmacoleg a Biotechnoleg | 10/2004 - 09/2005 |
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Baglor mewn Fferylliaeth (B.Pharm.) Prifysgol Dechnolegol Jawaharlal Nehru, India |
Fferyllfa | 10/1999 - 09/2003 |
Anrhydeddau a dyfarniadau
- Cymrawd yr Academi Addysg Uwch (FHEA) - Advance HEA a Phrifysgol Caerdydd (2026)
- Cwpan y Sylfaenwyr am yr Ymchwil Orau - 103fed Cyngres Offthalmolegol Rhydychen (2019)
- Sgôr arfarnu PDPR # 1 - Prifysgol Nottingham (2017)
- Poster Gwobr Gyntaf – 21ain Symposiwm Nottingham Eye (2017)
- Cymrodoriaeth Ymchwil Elizabeth C. King o'r un enw – Prifysgol Nottingham (2015)
- AUM Bywyd-Technoleg Gwobr Ôl-ddoethurol - Prifysgol Pennsylvania (2013)
- Gwobr Gyntaf Nottingham - 14eg Symposiwm Nottingham Eye (2010)
- Andrew Hendry Gwobr Ôl-raddedig Endowed - Prifysgol Nottingham (2010)
- Gwobr Gyntaf - Diwrnod Ymchwil Drosiadol 1af - Prifysgol Nottingham (2009)
- David Meyer Gwobr Ymchwil - 13eg Symposiwm Nottingham Eye (2009)
- Gwobr Papur Gwyddonol Gorau – Cyfarfod Asia-ARVO (2009)
- Gwobr Cymrodoriaeth Teithio – Cyfarfod Asia-ARVO (2009)
- Gwobr Teithio Ysgol i Raddedigion - Prifysgol Nottingham (2009)
- Teilyngdod – rhaglen MSc; Prifysgol Sheffield Hallam (2005)
- Rhagoriaeth – Rhaglen B. Pharm; Prifysgol JNT (2003)
- Rhagoriaeth – Bwrdd Addysg Ganolradd, Hyderabad (1998)
- Rhagoriaeth – Bwrdd Addysg Uwchradd, Hyderabad (1996)
Aelodaethau proffesiynol
a) Aelodaeth academaidd / broffesiynol:
- Academi Addysg Uwch (2026 - presennol)
- Cymdeithas Imiwnoleg Prydain (2021 – presennol)
- Cymdeithas Offthalmolegol Rhydychen (2019 – presennol)
- Pwyllgor Adolygu Ymchwil Ysgolion – Prifysgol Nottingham (2018 – 2022)
- Pwyllgor Diogelwch Ysgolion – Prifysgol Nottingham (2017 – 2022)
- Cynllun Mentora Ysgolion – Prifysgol Nottingham (2017 – 2022)
- Cymdeithas Heintiau Prydain (2016 – presennol)
- Cymdeithas Ategu Rhyngwladol (2010 – 2014)
- Cymdeithas Ôl-ddoethurol Biofeddygol, Prifysgol Pennsylvania (2010 – 2014)
- Cymdeithas Imiwnoleg Mwcosaidd (2009 – 2011)
- Cymdeithas Ymchwil mewn Golwg ac Offthalmoleg (2008 – presennol)
- Cymdeithas America ar gyfer Hyrwyddo Gwyddoniaeth (2007 – 2008)
b) Trwyddedu:
- Deiliad Trwydded Prosiect Anifeiliaid y Swyddfa Gartref (PPLh), y DU
- Trwydded Bersonol Anifeiliaid y Swyddfa Gartref (PIL A + B), y DU
- Defnyddiwr Trwyddedig – Pwyllgor Gofal a Defnydd Anifeiliaid Sefydliadol, Prifysgol Pennsylvania, UDA
- Fferyllydd Cofrestredig - Cyngor Fferylliaeth Talaith Telangana, India
Safleoedd academaidd blaenorol
| Blynyddoedd | Safle | Trefniadaeth |
| 2022 - presennol | Darlithydd (Athro Cynorthwyol) | Ysgol Optometreg a Gwyddorau Golwg, Prifysgol Caerdydd, UK |
| 2018 - 2022 | Uwch Gymrawd Ymchwil | Offthalmoleg Academaidd, Prifysgol Nottingham, UK |
| 2015 - 2018 | Elizabeth C. King Uwch Wyddonydd Ymchwil | Offthalmoleg Academaidd, Prifysgol Nottingham, UK |
| 2014 - 2015 | Athro Cynorthwyol (trac addysgu) | Coleg Fferylliaeth, Prifysgol Qassim, KSA |
| 2010 - 2014 | Ymchwilydd Ôl-ddoethurol | Ysgol Meddygaeth, Prifysgol Pennsylvania, UDA |
| 2006 - 2010 | Ysgolhaig PhD | Div o Offthalmoleg a Gwyddorau Gweledol, Prifysgol Nottingham, UK |
| 2005 - 2006 | Cynorthwy-ydd Ymchwil | Div o Offthalmoleg a Gwyddorau Gweledol, Prifysgol Nottingham, UK |
Pwyllgorau ac adolygu
| Bwrdd golygyddol cyfnodolion: |
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| Adolygu ar gyfer cyrff grant |
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| Adolygu ar gyfer cyfnodolion gwyddonol: |
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Meysydd goruchwyliaeth
Mae gen i ddiddordeb mewn goruchwylio myfyrwyr PhD ym meysydd:
- Peptidau gwrthficrobaidd (peptidau Host-amddiffyn): Datblygu a phrofi mewn systemau model ex-vivo ac in-vivo
- Datblygu therapïau amgen i frwydro yn erbyn ymwrthedd gwrthficrobaidd (AMR)
- Therapïau newydd ar gyfer rheoli haint cornbilen (keratitis microbaidd)
- Asiantau gwrth-bioffilm
- Astudio pathobioleg keratitis microbaidd: Ymchwilio i rôl llwybrau actifadu ategu mewn difrifoldeb clefydau
Contact Details
+44 29208 75347
Optometreg a Gwyddorau'r Golwg , Llawr 3, Ystafell 3.04, Heol Maendy, Cathays, Caerdydd, CF24 4HQ
Themâu ymchwil
Arbenigeddau
- Afiechydon heintus
- ymwrthedd gwrthficrobaidd
- Imiwnedd cynhenid
- Datblygu cyffuriau
- Cyflwyno cyffuriau