Yr Athro David Price

2026

• Lang-Meli, J. et al., 2026. Robust HLA-B-restricted CD8+ T cell responses in chronic HBV infection. JHEP Reports 8 (8) 101868. (10.1016/j.jhepr.2026.101868)
• Oberhardt, V. et al., 2026. Fate of hepatitis D virus-specific CD8+ T cells during bulevirtide monotherapy in patients with chronic hepatitis delta☆. JHEP Reports 101970. (10.1016/j.jhepr.2026.101970)
• Marsden, M. et al. 2026. Cytomegalovirus-induced T cell responses accelerate Alzheimer’s disease progression in mice. Brain awag043. (10.1093/brain/awag043)
• Keat, S. B. K. et al. 2026. Activation of the lectin pathway drives persistent complement dysregulation in long COVID. Immunology 178 (2), pp.261-268. (10.1111/imm.70110)
• Rivera Ballesteros, O. et al., 2026. CXCR5 identifies stem-like resident memory CD8+ T cells enriched for latent EBV specificity in tonsils. Science Advances 12 (2) eady 8316. (10.1126/sciadv.ady8316)

2025

• Ponsford, M. et al. 2025. TAP-I Deficiency presenting with chronic granulomatous rubella virus-driven cutaneous ulceration: a case report and scoping literature review. Journal of Clinical Immunology 46 1. (10.1007/s10875-025-01919-6)
• Lukyanov, D. K. et al., 2025. Splicing-aware scRNA-Seq resolution reveals execution-ready programs in effector Tregs. PLoS Computational Biology 21 (11) e1013682. (10.1371/journal.pcbi.1013682)
• Moon, O. R. et al. 2025. TCR activation stimulates regulated intramembrane proteolysis of L-selectin by presenilin 1 and localized proteasomal degradation of the cytoplasmic tail. Journal of Biological Chemistry 301 (8) 110473. (10.1016/j.jbc.2025.110473)
• Toledo-Teixeira, D. A. et al., 2025. MyD88 signalling in B cells and antibody responses during Oropouche virus-induced neurological disease in mice. EBioMedicine 117 105815. (10.1016/j.ebiom.2025.105815)
• Niessl, J. et al., 2025. Tissue origin and virus specificity shape human CD8+ T cell cytotoxicity. Science Immunology 10 (109) eadq4881. (10.1126/sciimmunol.adq4881)
• Gao, Y. et al., 2025. Identification of soluble biomarkers that associate with distinct manifestations of long COVID. Nature Immunology 26 , pp.692–705. (10.1038/s41590-025-02135-5)
• Proal, A. D. et al., 2025. Targeting the SARS-CoV-2 reservoir in long COVID. The Lancet Infectious Diseases 25 (5), pp.294-306. (10.1016/S1473-3099(24)00769-2)
• Lukyanov, D. K. et al., 2025. Repertoire-based mapping and time-tracking of T helper cell subsets in scRNA-Seq. Frontiers in Immunology 16 1536302. (10.3389/fimmu.2025.1536302)
• Autaa, G. et al., 2025. Ageing and inflammation limit the induction of SARS-CoV-2-specific CD8+ T cell responses in severe COVID-19. JCI Insight 10 (4) e180867. (10.1172/jci.insight.180867)
• Berneman, Z. N. et al., 2025. WT1-mRNA dendritic cell vaccination of patients with glioblastoma multiforme, malignant pleural mesothelioma, metastatic breast cancer, and other solid tumors: type 1 T-lymphocyte responses are associated with clinical outcome. Journal of Hematology and Oncology 18 (1) 9. (10.1186/s13045-025-01661-x)

2024

• Mora-Bitria, L. et al., 2024. Inhibitory KIRs decrease HLA class II-mediated protection in Type 1 Diabetes.. PLoS Genetics 20 (12) e1011456. (10.1371/journal.pgen.1011456)
• Giannoni, E. et al., 2024. Sepsis shapes the human γδ TCR repertoire in an age- and pathogen-dependent manner. European Journal of Immunology 54 (10) 2451190. (10.1002/eji.202451190)
• White, E. et al., 2024. Clonal succession after prolonged antiretroviral therapy rejuvenates CD8+ T cell responses against HIV-1. Nature Immunology 25 (9), pp.1555–1564. (10.1038/s41590-024-01931-9)
• Dallan, B. et al., 2024. Age differentially impacts adaptive immune responses induced by adenoviral versus mRNA vaccines against COVID-19. Nature Aging 4 (8), pp.1121–1136. (10.1038/s43587-024-00644-w)
• Heim, K. et al., 2024. Attenuated effector T cells are linked to control of chronic HBV infection. Nature Immunology 25 (9), pp.1650-1662. (10.1038/s41590-024-01928-4)
• Simpson, J. et al., 2024. Immunotoxin-mediated depletion of Gag-specific CD8+ T cells undermines natural control of SIV. JCI Insight 9 (14)(10.1172/jci.insight.174168)
• Baillie, K. et al. 2024. Complement dysregulation is a prevalent and therapeutically amenable feature of long COVID. Med 5 (3), pp.239-253. (10.1016/j.medj.2024.01.011)
• Cabral-Piccin, M. P. et al., 2024. CD8+ T cell priming is quantitatively but not qualitatively impaired in people with HIV-1 on antiretroviral therapy. AIDS 38 (2), pp.161-166. (10.1097/QAD.0000000000003746)

2023

• Cai, C. et al., 2023. SARS-CoV-2 vaccination enhances the effector qualities of spike-specific T cells induced by COVID-19. Science Immunology 8 (90)(10.1126/sciimmunol.adh0687)
• Winkler, F. et al., 2023. Enolase represents a metabolic checkpoint controlling the differential exhaustion programmes of hepatitis virus-specific CD8 + T cells. Gut 72 (10), pp.1971-1984. (10.1136/gutjnl-2022-328734)
• Roger, L. et al. 2023. T cell memory revisited using single telomere length analysis. Frontiers in Immunology 14 1100535. (10.3389/fimmu.2023.1100535)
• Knezevic, L. et al., 2023. High-affinity CD8 variants enhance the sensitivity of pMHCI antigen recognition via low-affinity TCRs. Journal of Biological Chemistry 299 (8) 104981. (10.1016/j.jbc.2023.104981)
• Rubina, A. et al. 2023. ADAM17 targeting by human cytomegalovirus remodels the cell surface proteome to simultaneously regulate multiple immune pathways. Proceedings of the National Academy of Sciences 120 (33) e2303155120. (10.1073/pnas.2303155120)
• Buggert, M. et al., 2023. Human circulating and tissue-resident memory CD8+ T cells. Nature Immunology 24 (7), pp.1076-1086. (10.1038/s41590-023-01538-6)
• Clement, M. et al. 2023. Inhibitory IL-10-producing CD4+ T cells are T-bet-dependent and facilitate cytomegalovirus persistence via coexpression of arginase-1. eLife 12 e79165. (10.7554/eLife.79165)
• Chen, Y. et al., 2023. Group A Streptococcus induces CD1a-autoreactive T cells and promotes psoriatic inflammation. Science Immunology 8 (84) eadd9232. (10.1126/sciimmunol.add9232)
• Adamo, S. et al., 2023. Memory profiles distinguish cross-reactive and virus-specific T cell immunity to mpox. Cell Host & Microbe 31 (6), pp.928-936. (10.1016/j.chom.2023.04.015)
• Eser, T. M. et al., 2023. Nucleocapsid-specific T cell responses associate with control of SARS-CoV-2 in the upper airways before seroconversion. Nature Communications 14 (1) 2952. (10.1038/s41467-023-38020-8)
• Fahad, A. S. et al., 2023. Cell activation-based screening of natively paired human T cell receptor repertoires. Scientific Reports 13 8011. (10.1038/s41598-023-31858-4)
• Ciacchi, L. et al., 2023. CD4+ T cell-mediated recognition of a conserved cholesterol-dependent cytolysin epitope generates broad antibacterial immunity. Immunity 56 (5), pp.1082-1097. (10.1016/j.immuni.2023.03.020)
• Cabral-Piccin, M. P. et al., 2023. Primary role of type I interferons for the induction of functionally optimal antigen-specific CD8+ T cells in HIV infection. EBioMedicine 91 104557. (10.1016/j.ebiom.2023.104557)
• Shepherd, F. R. et al. 2023. The superantigens SpeC and TSST-1 specifically activate TRBV12-3/12-4+ memory T cells. Communications Biology 6 78. (10.1038/s42003-023-04420-1)
• Proietto, D. et al., 2023. Ageing curtails the diversity and functionality of nascent CD8 + T cell responses against SARS-CoV-2. Vaccines 11 (1) 154. (10.3390/vaccines11010154)
• Proal, A. D. et al., 2023. SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC). Nature Immunology 24 , pp.1616-1627. 10.1038/s41590-023-01601-2. (10.1038/s41590-023-01601-2)

2022

• Fahad, A. S. et al., 2022. Immortalization and functional screening of natively paired human T cell receptor repertoires. Protein Engineering, Design & Selection 35 gzab034. (10.1093/protein/gzab034)
• Kemming, J. et al., 2022. Mechanisms of CD8+ T cell failure in chronic hepatitis E virus infection. Journal of Hepatology 77 (4), pp.978-990. (10.1016/j.jhep.2022.05.019)
• Goncharov, M. et al., 2022. VDJdb in the pandemic era: a compendium of T cell receptors specific for SARS-CoV-2. Nature Methods 19 (9), pp.1017–1019. (10.1038/s41592-022-01578-0)
• Fielding, C. A. et al. 2022. SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies. eLife 11 (10.7554/eLife.74489)
• Pymm, P. et al., 2022. Epitope length variants balance protective immune responses and viral escape in HIV-1 infection. Cell Reports 38 (9) 110449. (10.1016/j.celrep.2022.110449)
• Nicoli, F. et al., 2022. Altered basal lipid metabolism underlies the functional impairment of naive CD8+ T cells in elderly humans. The Journal of Immunology 208 (3), pp.562–570. (10.4049/jimmunol.2100194)
• Gao, Y. et al., 2022. Ancestral SARS-CoV-2-specific T cells cross-recognize the Omicron variant. Nature Medicine 28 (3), pp.472-476. (10.1038/s41591-022-01700-x)

2021

• Campion, S. L. et al., 2021. Preexisting memory CD4+ T cells contribute to the primary response in an HIV-1 vaccine trial. Journal of Clinical Investigation 131 (23) e150823. (10.1172/JCI150823)
• Niessl, J. et al., 2021. Identification of resident memory CD8+ T cells with functional specificity for SARS-CoV-2 in unexposed oropharyngeal lymphoid tissue. Science Immunology 6 (64) eabk0894. (10.1126/sciimmunol.abk0894)
• Man, S. et al. 2021. Synthetic peptides with inadvertent chemical modifications can activate potentially autoreactive T cells. The Journal of Immunology 207 (4), pp.1009-1017. (10.4049/jimmunol.2000756)
• Clement, M. et al. 2021. CD8 coreceptor-mediated focusing can reorder the agonist hierarchy of peptide ligands recognized via the T cell receptor. Proceedings of the National Academy of Sciences 118 (29) e2019639118. (10.1073/pnas.2019639118)
• Heim, K. et al., 2021. TOX defines the degree of CD8+ T cell dysfunction in distinct phases of chronic HBV infection. Gut 70 , pp.1550-1560. (10.1136/gutjnl-2020-322404)
• Nicoli, F. et al., 2021. Use of a novel peptide welding technology platform for the development of B- and T-Cell epitope-based vaccines. Vaccines 9 (5) 526. (10.3390/vaccines9050526)
• Hensel, N. et al., 2021. Memory-like HCV-specific CD8+ T cells retain a molecular scar after cure of chronic HCV infection. Nature Immunology 22 (2), pp.229–239. (10.1038/s41590-020-00817-w)
• Vlachava, V. et al. 2021. Monoclonal antibodies targeting nonstructural viral antigens can activate ADCC against human cytomegalovirus. Journal of Clinical Investigation 131 (4) e139296. (10.1172/JCI139296)
• Schulien, I. et al., 2021. Characterization of pre-existing and induced SARS-CoV-2-specific CD8+ T cells. Nature Medicine 27 (1)(10.1038/s41591-020-01143-2)

2020

• Galletti, G. et al., 2020. Two subsets of stem-like CD8+ memory T cell progenitors with distinct fate commitments in humans. Nature Immunology 21 , pp.1552-1562. (10.1038/s41590-020-0791-5)
• Kasatskaya, S. A. et al., 2020. Functionally specialized human CD4+ T-cell subsets express physicochemically distinct TCRs. eLife 9 e57063. (10.7554/eLife.57063)
• Buggert, M. et al., 2020. The identity of human tissue-emigrant CD8+ T cells. Cell 183 (7), pp.1946-1961. (10.1016/j.cell.2020.11.019)
• Ahmed, R. et al., 2020. CD57+ Memory T Cells Proliferate In Vivo. Cell Reports 33 (11) 108501. (10.1016/j.celrep.2020.108501)
• Ghosh, S. et al., 2020. Extended clinical and immunological phenotype and transplant outcome in CD27 and CD70 deficiency. Blood 136 (23), pp.2638-2655. (10.1182/blood.2020006738)
• Narayanan, G. A. et al., 2020. The MAIT TCRβ chain contributes to discrimination of microbial ligand. Immunology and Cell Biology 98 (9), pp.770-781. (10.1111/imcb.12370)
• Weinfurter, J. T. et al., 2020. Identifying a minor histocompatibility antigen in mauritian cynomolgus macaques encoded by APOBEC3C. Frontiers in Immunology 11 586251. (10.3389/fimmu.2020.586251)
• Sekine, T. et al., 2020. Robust T cell immunity in convalescent individuals with asymptomatic or mild COVID-19. Cell 183 (1), pp.158-168. (10.1016/j.cell.2020.08.017)
• Passaes, C. et al., 2020. Optimal maturation of the SIV-Specific CD8+ T cell response after primary infection is associated with natural control of SIV: ANRS SIC study. Cell Reports 32 (12) 108174. (10.1016/j.celrep.2020.108174)
• Papagno, L. et al., 2020. The TLR9 ligand CpG ODN 2006 is a poor adjuvant for the induction of de novo CD8+ T-cell responses in vitro. Scientific Reports 10 (1) 11620. (10.1038/s41598-020-67704-0)
• Sekine, T. et al., 2020. TOX is expressed by exhausted and polyfunctional human effector memory CD8+ T cells. Science Immunology 5 (49) eaba7918. (10.1126/sciimmunol.aba7918)
• Hanna, S. J. et al. 2020. Slow progressors to type 1 diabetes lose islet autoantibodies over time, have few islet antigen-specific CD8+ T cells and exhibit a distinct CD95hi B cell phenotype. Diabetologia 63 , pp.1174-1185. Diabetologia volume 63, pages1174–1185(2020). (10.1007/s00125-020-05114-7)
• Pearson, F. E. et al., 2020. Human CLEC9A antibodies deliver Wilms' tumor 1 (WT1) antigen to CD141+ dendritic cells to activate naïve and memory WT1‐specific CD8+ T cells. Clinical and Translational Immunology 9 (10.1002/cti2.1141)
• Edwards, S. C. et al., 2020. A population of proinflammatory T cells coexpresses αβ and γδ T cell receptors in mice and humans. Journal of Experimental Medicine 217 (5) e20190834. (10.1084/jem.20190834)
• Starke, C. E. et al., 2020. SIV-specific CD8+ T cells are clonotypically distinct across lymphoid and mucosal tissues. Journal of Clinical Investigation 130 (2), pp.789-798. (10.1172/JCI129161)
• Brenna, E. et al., 2020. CD4+ T follicular helper cells in human tonsils and blood are clonally convergent but divergent from Non-Tfh CD4+ cells. Cell Reports 30 (1), pp.137-152. (10.1016/j.celrep.2019.12.016)
• Smith, C. J. et al., 2020. Stochastic expansions maintain the clonal stability of CD8+ T cell populations undergoing memory inflation driven by murine cytomegalovirus. Journal of Immunology 204 (1), pp.112-121. (10.4049/jimmunol.1900455)

2019

• Nguyen, S. et al., 2019. Elite control of HIV is associated with distinct functional and transcriptional signatures in lymphoid tissue CD8+ T cells. Science Translational Medicine 11 (523) eaax4077. (10.1126/scitranslmed.aax4077)
• De Simone, G. et al., 2019. CXCR3 identifies human naive CD8+ T cells with enhanced effector differentiation potential. Journal of Immunology 203 (12), pp.3179-3189. (10.4049/jimmunol.1901072)
• Appanna, G. D. et al. 2019. Rituximab depletion of intrahepatic B cells to control refractory hepatic autoimmune overlap syndrome. QJM: An International Journal of Medicine 112 (10), pp.793-795. (10.1093/qjmed/hcz161)
• Thomas, S. et al., 2019. Framework engineering to produce dominant T cell receptors with enhanced antigen-specific function. Nature Communications 10 , pp.-. 4451. (10.1038/s41467-019-12441-w)
• Tauber, C. et al., 2019. Inefficient induction of circulating TAA-specific CD8+ T-cell responses in hepatocellular carcinoma. Oncotarget 10 (50), pp.5194-5206. (10.18632/oncotarget.27146)
• Liu, J. et al., 2019. The peripheral differentiation of human natural killer T cells. Immunology and Cell Biology 97 (6), pp.586-596. (10.1111/imcb.12248)
• Wong, E. B. et al., 2019. TRAV1-2+ CD8+ T-cells including oligoconal expansions of MAIT cells are enriched in the airways in human tuberculosis. Communications Biology 2 (1), pp.-. 203. (10.1038/s42003-019-0442-2)
• Karimzadeh, H. et al., 2019. Mutations in hepatitis D virus allow it to escape detection by CD8+ T Cells and evolve at the population level. Gastroenterology 156 (6), pp.1820-1833. (10.1053/j.gastro.2019.02.003)
• Schuch, A. et al., 2019. Phenotypic and functional differences of HBV core-specific versus HBV polymerase-specific CD8+ T cells in chronically HBV-infected patients with low viral load. Gut 68 , pp.905-915. (10.1136/gutjnl-2018-316641)
• Mohammed, R. N. et al. 2019. ADAM17-dependent proteolysis of L-selectin promotes early clonal expansion of cytotoxic T cells. Scientific Reports 9 5487. (10.1038/s41598-019-41811-z)
• Li, N. et al., 2019. Memory CD4+ T cells are generated in the human fetal intestine. Nature Immunology 20 , pp.301-312. (10.1038/s41590-018-0294-9)
• Mayassi, T. et al., 2019. Chronic inflammation permanently reshapes tissue-resident immunity in celiac disease. Cell 176 (5), pp.967-981.e19. (10.1016/j.cell.2018.12.039)
• McLaren, J. et al. 2019. IL-33 augments virus-specific memory T Cell inflation and potentiates the efficacy of an attenuated cytomegalovirus-based vaccinea. Journal of Immunology 202 (3), pp.943-955. (10.4049/jimmunol.1701757)
• Edwards, E. S. et al., 2019. Activating PIK3CD mutations impair human cytotoxic lymphocyte differentiation and function and EBV immunity. Journal of Allergy and Clinical Immunology 143 (1), pp.276-291.e6. (10.1016/j.jaci.2018.04.030)
• Shimauchi, T. et al. 2019. Dendritic cells promote the spread of human T-cell leukemia virus type 1 via bidirectional interactions with CD4+ T cells. Journal of Investigative Dermatology 139 (1), pp.157-166. (10.1016/j.jid.2018.06.188)
• Kemming, J. et al., 2019. ERAP1 allotypes shape the epitope repertoire of virus-specific CD8+ T cell responses in acute hepatitis C virus infection. Journal of Hepatology 70 (6), pp.1072-1081. (10.1016/j.jhep.2019.01.034)

2018

• Nicoli, F. et al., 2018. Naïve CD8+ T-cells engage a versatile metabolic program upon activation in humans and differ energetically from memory CD8+ T-cells. Frontiers in Immunology 9 , pp.-. 2736. (10.3389/fimmu.2018.02736)
• Boelen, L. et al., 2018. Inhibitory killer cell immunoglobulin-like receptors strengthen CD8+ T cell-mediated control of HIV-1, HCV, and HTLV-1. Science Immunology 3 (29) eaao2892. (10.1126/sciimmunol.aao2892)
• Powell, W. E. et al. 2018. Loss of CXCR3 expression on memory B cells in individuals with long-standing type 1 diabetes. Diabetologia 61 , pp.1794-1803. (10.1007/s00125-018-4651-x)
• Pogorelyy, M. V. et al., 2018. Exploring the pre-immune landscape of antigen-specific T cells. Genome Medicine 10 68. (10.1186/s13073-018-0577-7)
• Morabito, K. M. et al., 2018. Memory inflation drives tissue-resident memory CD8+ T cell maintenance in the lung after intranasal vaccination with murine cytomegalovirus. Frontiers in Immunology 9 1861. (10.3389/fimmu.2018.01861)
• Costa del Amo, P. et al., 2018. Human TSCM cell dynamics in vivo are compatible with long-lived immunological memory and stemness. PLoS Biology 16 (6) e2005523. (10.1371/journal.pbio.2005523)
• Buggert, M. et al., 2018. Identification and characterization of HIV-specific resident memory CD8 + T cells in human lymphoid tissue. Science Immunology 3 (24) eaar4526. (10.1126/sciimmunol.aar4526)
• Martin, M. P. et al., 2018. Killer cell immunoglobulin-like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1. Journal of Clinical Investigation 128 (5), pp.1903. (10.1172/JCI98463)
• Wun, K. S. et al., 2018. T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids. Nature Immunology 19 , pp.397-406. (10.1038/s41590-018-0065-7)
• Miles, J. J. et al. 2018. Peptide mimic for influenza vaccination using nonnatural combinatorial chemistry. Journal of Clinical Investigation 128 (4), pp.1569-1580. (10.1172/JCI91512)
• James, E. A. et al., 2018. Combinatorial detection of autoreactive CD8+ T cells with HLA-A2 multimers: a multi-centre study by the Immunology of Diabetes Society T Cell Workshop. Diabetologia 61 (3), pp.658-670. (10.1007/s00125-017-4508-8)
• Culina, S. et al., 2018. Islet-reactive CD8+ T cell frequencies in the pancreas, but not in blood, distinguish type 1 diabetic patients from healthy donors. Science Immunology 3 (20) eaao4013. (10.1126/sciimmunol.aao4013)
• Shugay, M. et al., 2018. VDJdb: a curated database of T-cell receptor sequences with known antigen specificity. Nucleic Acids Research 46 (D1), pp.D419-D427. (10.1093/nar/gkx760)
• Lissina, A. et al., 2018. Divergent roles for antigenic drive in the aetiology of primary versus dasatinib-associated CD8+ TCR-Vβ+ expansions. Scientific Reports 8 (1) 2534. (10.1038/s41598-017-18062-x)

2017

• Reuter, M. A. et al., 2017. HIV-specific CD8 + T cells exhibit reduced and differentially regulated Cytolytic activity in Lymphoid tissue. Cell Reports 21 (12), pp.3458-3470. (10.1016/j.celrep.2017.11.075)
• Van Braeckel-Budimir, N. et al., 2017. A T cell receptor locus harbors a malaria-specific immune response gene. Immunity 47 (5), pp.835-847.e4. (10.1016/j.immuni.2017.10.013)
• Culshaw, A. et al., 2017. Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8+ T cell response. Nature Immunology 18 , pp.1228-1237. (10.1038/ni.3850)
• Anguille, S. et al., 2017. Dendritic cell vaccination as postremission treatment to prevent or delay relapse in acute myeloid leukemia. Blood 130 (15), pp.1713-1721. (10.1182/blood-2017-04-780155)
• Zanon, V. et al., 2017. Curtailed T-cell activation curbs effector differentiation and generates CD8+ T cells with a naturally-occurring memory stem cell phenotype. European Journal of Immunology 47 (9), pp.1468-1476. (10.1002/eji.201646732)
• Chen, H. et al., 2017. Synergistic targeting of breast cancer stem-like cells by human γδ T cells and CD8+ T cells. Immunology and Cell Biology 95 (7), pp.620-629. (10.1038/icb.2017.21)
• Murrell, I. et al. 2017. The pentameric complex drives immunologically covert cell -cell transmission of wild-type human cytomegalovirus. Proceedings of the National Academy of Sciences 114 (23), pp.6104-6109. (10.1073/pnas.1704809114)
• Gutjahr, A. et al., 2017. Cutting edge: a dual TLR2 and TLR7 ligand induces highly potent humoral and cell-mediated immune responses. Journal of Immunology 198 (11), pp.4205-4209. (10.4049/jimmunol.1602131)
• Pymm, P. et al., 2017. MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape. Nature Structural and Molecular Biology 24 , pp.387-394. (10.1038/nsmb.3381)
• Davey, M. S. et al., 2017. Clonal selection in the human Vδ1 T cell repertoire indicates γδ TCR-dependent adaptive immune surveillance. Nature Communications 8 14760. (10.1038/ncomms14760)
• Smith, C. et al., 2017. Pre-emptive and therapeutic adoptive immunotherapy for nasopharyngeal carcinoma: Phenotype and effector function of T cells impact on clinical response. OncoImmunology 6 (2) e1273311. (10.1080/2162402X.2016.1273311)
• Abolhassani, H. et al., 2017. Combined immunodeficiency and Epstein-Barr virus-induced B cell malignancy in humans with inherited CD70 deficiency. Journal of Experimental Medicine 214 (1), pp.91. (10.1084/jem.20160849)
• Dockree, T. et al. 2017. CD8+ T-cell specificity is compromised at a defined MHCI/CD8 affinity threshold. Immunology and Cell Biology 95 (1), pp.68-76. (10.1038/icb.2016.85)
• Morabito, K. M. et al., 2017. Intranasal administration of RSV antigen-expressing MCMV elicits robust tissue-resident effector and effector memory CD8+ T cells in the lung. Mucosal Immunology 10 (2), pp.545-554. (10.1038/mi.2016.48)

2016

• Ahmed, R. et al. 2016. Human stem cell-like memory T cells are maintained in a state of dynamic flux. Cell Reports 17 (11), pp.2811-2818. (10.1016/j.celrep.2016.11.037)
• Clement, M. et al. 2016. Targeted suppression of autoreactive CD8+ T-cell activation using blocking anti-CD8 antibodies. Scientific Reports 6 35332. (10.1038/srep35332)
• Watson, H. A. et al., 2016. Purity of transferred CD8+ T cells is crucial for safety and efficacy of combinatorial tumor immunotherapy in the absence of SHP-1. Immunology and Cell Biology 94 (8)(10.1038/icb.2016.45)
• Pageon, S. V. et al., 2016. Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination. Proceedings of the National Academy of Sciences 113 (37), pp.E5454-E5463. (10.1073/pnas.1607436113)
• Szomolay, B. et al. 2016. Identification of human viral protein-derived ligands recognized by individual MHCI-restricted T-cell receptors. Immunology and Cell Biology 94 (6), pp.573-582. (10.1038/icb.2016.12)
• Caucheteux, S. M. et al. 2016. Polypropylene sulfide nanoparticle p24 vaccine promotes dendritic cell-mediated specific immune responses against HIV-1. Journal of Investigative Dermatology 136 (6), pp.1172-1181. (10.1016/j.jid.2016.01.033)
• de Paula Alves Sousa, A. et al., 2016. Intrathecal T-cell clonal expansions in patients with multiple sclerosis. Annals of Clinical and Translational Neurology 3 (6), pp.422-433. (10.1002/acn3.310)
• Pearson, J. A. et al. 2016. Proinsulin expression shapes the TCR repertoire but fails to control the development of low-avidity insulin-reactive CD8+ T cells. Diabetes 65 (6), pp.1679-1689. (10.2337/db15-1498)
• Vinton, C. et al., 2016. Mucosa-associated invariant T cells are systemically depleted in simian immunodeficiency virus-infected rhesus macaques. Journal of Virology 90 (9), pp.4520-4529. (10.1128/JVI.02876-15)
• Valkenburg, S. A. et al., 2016. Molecular basis for universal HLA-A*0201 - restricted CD8+ T-cell immunity against influenza viruses. Proceedings of the National Academy of Sciences of the United States of America 113 (16), pp.4440-4445. (10.1073/pnas.1603106113)
• Du, V. Y. et al., 2016. HIV-1-specific CD8 T cells exhibit limited cross-reactivity during acute infection. The Journal of Immunology 196 (8), pp.3276-3286. (10.4049/jimmunol.1502411)
• Saunders, P. M. et al., 2016. Killer cell immunoglobulin-like receptor 3DL1 polymorphism defines distinct hierarchies of HLA class I recognition. Journal of Experimental Medicine 213 (5), pp.791-807. (10.1084/jem.20152023)
• Ridley, A. et al., 2016. Activation-induced killer cell immunoglobulin-like receptor 3DL2 binding to HLA-B27 licenses pathogenic T cell differentiation in spondyloarthritis. Arthritis and Rheumatology 68 (4), pp.901-914. (10.1002/art.39515)
• Jones, K. et al., 2016. The impact of HLA-class I and EBV-latency-II antigen-specific CD8+T-cells on the pathogenesis of EBV+ Hodgkin Lymphoma. Clinical and Experimental Immunology 183 (2), pp.206-220. (10.1111/cei.12716)
• Briceño, O. et al., 2016. Reduced naïve CD8+T-cell priming efficacy in elderly adults. Aging Cell 15 (1), pp.14-21. (10.1111/acel.12384)
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2015

• Holland, C. J. et al., 2015. Enhanced detection of antigen-specific CD4+ T cells using altered peptide flanking residue peptide-MHC class II multimers. Journal of Immunology 195 (12), pp.5827-5836. (10.4049/jimmunol.1402787)
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• Townsley, E. et al., 2015. Interaction of a dengue virus NS1-derived peptide with the inhibitory receptor KIR3DL1 on natural killer cells. Clinical & Experimental Immunology 183 (3), pp.419-430. (10.1111/cei.12722)
• Ladell, K. et al. 2015. Continuous antigenic stimulation of DO11.10 TCR transgenic mice in the presence or absence of IL-1: possible implications for mechanisms of T cell depletion in HIV disease. Journal of Immunology 195 (9), pp.4096-4105. (10.4049/jimmunol.1500799)
• Pombo, C. et al., 2015. Elevated expression of CD160 and 2B4 defines a cytolytic HIV-specific CD8+T-cell population in elite controllers. Journal of Infectious Diseases 212 (9), pp.1376-1386. (10.1093/infdis/jiv226)
• Mohns, M. S. et al., 2015. Expansion of Simian Immunodeficiency Virus (SIV)-specific CD8 T cell lines from SIV-naive Mauritian cynomolgus macaques for adoptive transfer. Journal of Virology 89 (19), pp.9748-9757. (10.1128/JVI.00993-15)
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• Petersen, J. et al., 2015. Determinants of gliadin-specific T cell selection in celiac disease. The Journal of Immunology 194 (12), pp.6112-6122. (10.4049/jimmunol.1500161)
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• Skowera, A. et al., 2015. β-Cell-specific CD8 T Cell phenotype in Type 1 diabetes reflects chronic autoantigen exposure. Diabetes 64 (3), pp.916-925. (10.2337/db14-0332)
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• Motozono, C. et al. 2015. Clonotypically similar hybrid ab T cell receptors can exhibit markedly different surface expression, antigen specificity and cross-reactivity. Clinical and Experimental Immunology 180 (3), pp.560-570. (10.1111/cei.12610)
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• Schmied, S. et al., 2015. Analysis of the functional WT1-specific T-cell repertoire in healthy donors reveals a discrepancy between CD4+and CD8+memory formation. Immunology 145 (4), pp.558-569. (10.1111/imm.12472)

2014

• Willis, G. R. et al. 2014. Young women with polycystic ovary syndrome have raised levels of circulating annexin V-positive platelet microparticles. Human Reproduction 29 (12), pp.2756-2763. (10.1093/humrep/deu281)
• Collins, P. J. et al. 2014. Improving our understanding of CXCL14, one of the few remaining unknowns in chemokine biology [Abstract]. Immunology 143 (S2), pp.85-85. (10.1111/imm.12406)
• Hill, B. J. et al., 2014. Epitope specificity delimits the functional capabilities of vaccine-induced CD8 T Cell populations. The Journal of Immunology 193 (11), pp.5626-5636. (10.4049/jimmunol.1401017)
• Pearson, J. et al., 2014. Analysis of the repertoire of insulin-reactive CD8(+) T cells [Abstract]. Immunology 143 (S2), pp.152-152. (10.1111/imm.12406)
• Connolly, K. D. et al. 2014. Lipoprotein-apheresis reduces circulating microparticles in individuals with familial hypercholesterolemia. Journal of Lipid Research 55 , pp.2064-2072. (10.1194/jlr.M049726)
• Bengsch, B. et al., 2014. Identification of a TSCM phenotype HCV-specific CD8+T cell response with superior functionality in chronic HCV infection [Abstract]. Hepatology 60 , pp.1071A-1072A. 1815.
• Taylor, G. S. et al., 2014. A recombinant modified vaccinia Ankara vaccine encoding Epstein-Barr virus (EBV) target antigens: a phase I trial in UK patients with EBV-positive cancer. Clinical Cancer Research 20 (19), pp.5009-5022. (10.1158/1078-0432.CCR-14-1122-T)
• Kløverpris, H. N. et al., 2014. Programmed death-1 expression on HIV-1-specific CD8+ T cells is shaped by epitope specificity, T-cell receptor clonotype usage and antigen load. AIDS 28 (14), pp.2007-2021. (10.1097/QAD.0000000000000362)
• Gold, M. C. et al., 2014. MR1-restricted MAIT cells display ligand discrimination and pathogen selectivity through distinct T cell receptor usage. Journal of Experimental Medicine 211 (8), pp.1601-1610. (10.1084/jem.20140507)
• Laydon, D. J. et al., 2014. Quantification of HTLV-1 clonality and TCR diversity. PLoS Computational Biology 10 (6) e1003646. (10.1371/journal.pcbi.1003646)
• Flecken, T. et al., 2014. Immunodominance and functional alterations of tumor-associated antigen-specific CD8+T-cell responses in hepatocellular carcinoma. Hepatology 59 (4), pp.1415-1426. (10.1002/hep.26731)
• O'Connor, G. M. et al., 2014. Mutational and structural analysis of KIR3DL1 reveals a lineage-defining allotypic dimorphism that impacts both HLA and peptide sensitivity. Journal of Immunology 192 (6), pp.2875-2884. (10.4049/jimmunol.1303142)
• Melamed, A. et al., 2014. Clonality of HTLV-2 in natural infection. PLoS Pathogens 10 (3), pp.e1004006. (10.1371/journal.ppat.1004006)
• Bridgeman, J. S. et al. 2014. CD3ζ-based chimeric antigen receptors mediate T cell activation viacis- andtrans-signalling mechanisms: implications for optimization of receptor structure for adoptive cell therapy. Clinical and Experimental Immunology 175 (2), pp.258-267. (10.1111/cei.12216)
• Lissina, A. et al., 2014. The link between CD8+ T-cell antigen-sensitivity and HIV-suppressive capacity depends on HLA restriction, target epitope and viral isolate. AIDS 28 (4), pp.477-486. (10.1097/QAD.0000000000000175)
• Dolton, G. M. et al. 2014. Comparison of peptide-major histocompatibility complex tetramers and dextramers for the identification of antigen-specific T cells. Clinical and Experimental Immunology 177 (1), pp.47-63. (10.1111/cei.12339)
• Ondondo, B. et al. 2014. Progression of carcinogen-induced fibrosarcomas is associated with the accumulation of naïve CD4+ T cellsviablood vessels and lymphatics. International Journal of Cancer 134 (9), pp.2156-2167. (10.1002/ijc.28556)

2013

• Scurr, M. J. et al. 2013. Highly prevalent colorectal cancer-infiltrating LAP+ Foxp3- T cells exhibit more potent immunosuppressive activity than Foxp3+ regulatory T cells. Mucosal Immunology n/a (10.1038/mi.2013.62)
• van den Berg, H. A. et al., 2013. Cellular-level versus receptor-level response threshold hierarchies in T-cell activation. Frontiers in Immunology 4 250. (10.3389/fimmu.2013.00250)
• Casazza, J. et al., 2013. Therapeutic vaccination expands and improves the function of the HIV-specific memory T-Cell repertoire. International Journal of Infectious Diseases 207 (12), pp.1829-1840. (10.1093/infdis/jit098)
• Liu, Y. et al., 2013. Highly divergent T-cell receptor binding modes underlie specific recognition of a bulged viral peptide bound to a human leukocyte antigen class I molecule. Journal of Biological Chemistry 288 (22), pp.15442-15454. (10.1074/jbc.M112.447185)
• Motozono, C. et al., 2013. CD8+ T cell cross-reactivity profiles and HIV-1 immune escape towards an HLA-B35-restricted immunodominant Nef epitope. PLoS ONE 8 (6) e66152. (10.1371/journal.pone.0066152)
• Budimir, N. et al., 2013. Critical role of TLR7 signaling in the priming of cross-protective Cytotoxic T lymphocyte responses by a whole inactivated influenza virus vaccine. PLoS ONE 8 (5) e63163. (10.1371/journal.pone.0063163)
• Lugli, E. et al., 2013. Superior T memory stem cell persistence supports long-lived T cell memory. The Journal of Clinical Investigation 123 (2), pp.594-599. (10.1172/JCI66327)
• Beziat, V. et al., 2013. NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRS. Blood 121 (14), pp.2678-2688. (10.1182/blood-2012-10-459545)
• Budimir, N. et al., 2013. Heterosubtypic cross-protection induced by whole inactivated influenza virus vaccine in mice: influence of the route of vaccine administration. Influenza and Other Respiratory Viruses 7 (6), pp.1202-1209. (10.1111/irv.12142)
• Chattopadhyay, P. et al., 2013. Holoendemic malaria exposure is associated with altered epstein-barr virus-specific CD8+ T-cell differentiation. Journal of Virology 87 (3), pp.1779-1788. (10.1128/JVI.02158-12)
• Ekeruche, J. et al. 2013. Peptide length determines the outcome of TCR/peptide-MHCI engagement. Blood 121 (7), pp.1112-1123. (10.1182/blood-2012-06-437202)
• Greenaway, H. Y. et al., 2013. NKT and MAIT invariant TCRα sequences can be produced efficiently by VJ gene recombination. Immunobiology 218 (2), pp.213-224. (10.1016/j.imbio.2012.04.003)
• Harris, M. et al., 2013. Acute-Phase CD8 T cell responses that select for escape variants are needed to control live attenuated simian immunodeficiency virus. Journal of Virology 87 (16), pp.9353-9364. (10.1128/JVI.00909-13)
• Iglesias, M. C. et al., 2013. Immunodominance of HLA-B27-restricted HIV KK10-specific CD8+ T-cells is not related to naïve precursor frequency [Letter]. Immunology Letters 149 (1-2), pp.119-122. (10.1016/j.imlet.2012.10.002)
• Koning, D. et al., 2013. CD8+ TCR repertoire formation is guided primarily by the peptide component of the antigenic complex. The Journal of Immunology 190 (3), pp.931-939. (10.4049/jimmunol.1202466)
• Ladell, K. I. et al. 2013. A molecular basis for the control of preimmune escape variants by HIV-specific CD8+ T cells. Immunity 38 (3), pp.425-436. (10.1016/j.immuni.2012.11.021)
• Petrovas, C. et al., 2013. High production rates sustain in vivo levels of PD-1high simian immunodeficiency virus-specific CD8 T cells in the face of rapid clearance. Journal of Virology 87 (17), pp.9836-9844. (10.1128/JVI.01001-13)
• Quinn, K. M. et al., 2013. Comparative analysis of the magnitude, quality, phenotype, and protective capacity of simian immunodeficiency virus gag-specific CD8+ T cells following human-, simian-, and chimpanzee-derived recombinant adenoviral vector immunization. The Journal of Immunology 190 (6), pp.2720-2735. (10.4049/jimmunol.1202861)
• Roux, A. et al., 2013. CMV driven CD8+ T-cell activation is associated with acute rejection in lung transplantation. Clinical Immunology 148 (1), pp.16-26. (10.1016/j.clim.2013.03.012)
• Vavassori, S. et al., 2013. Butyrophilin 3A1 binds phosphorylated antigens and stimulates human γδ T cells. Nature Immunology 14 (9), pp.908-916. (10.1038/ni.2665)

2012

• Price, D. 2012. Horizons in Medicine 24: molecules, mechanisms and medicines [Editorial]. Clinical Medicine 12 (Supp 6), pp.s1. (10.7861/clinmedicine.12-6-s1)
• McCully, M. L. et al. 2012. Epidermis instructs skin homing receptor expression in human T cells. Blood 120 (23), pp.4591-4598. (10.1182/blood-2012-05-433037)
• Baum, P. D. , Venturi, V. and Price, D. 2012. Wrestling with the repertoire: the promise and perils of next generation sequencing for antigen receptors. European Journal of Immunology 42 (11), pp.2834-2839. (10.1002/eji.201242999)
• Hindley, J. P. et al. 2012. T-cell trafficking facilitated by high endothelial venules is required for tumor control after regulatory T cell depletion. Cancer Research 72 (21), pp.5473-5482. (10.1158/0008-5472.CAN-12-1912)
• Ekeruche-Makinde, J. et al., 2012. T-cell receptor-optimized peptide skewing of the T-cell repertoire can enhance antigen targeting. Journal of Biological Chemistry 287 (44), pp.37269-37281. (10.1074/jbc.M112.386409)
• Cole, D. K. et al. 2012. The molecular determinants of CD8 co-receptor function. Immunology 137 (2), pp.139-148. (10.1111/j.1365-2567.2012.03625.x)
• Li, H. et al., 2012. Recombinatorial biases and convergent recombination determine interindividual TCR  sharing in murine thymocytes. The Journal of Immunology 189 (5), pp.2404-2413. (10.4049/jimmunol.1102087)
• Johnson, M. J. et al., 2012. Type I IFN induced by adenovirus serotypes 28 and 35 has multiple effects on T cell immunogenicity. The Journal of Immunology 188 (12), pp.6109-6118. (10.4049/jimmunol.1103717)
• Liddy, N. et al., 2012. Monoclonal TCR-redirected tumor cell killing. Nature Medicine 18 (6), pp.980-987. (10.1038/nm.2764)
• Cole, D. et al. 2012. Modification of the carboxy-terminal flanking region of a universal influenza epitope alters CD4+ T-cell repertoire selection. Nature Communications 3 665. (10.1038/ncomms1665)
• Janbazian, L. et al., 2012. Clonotype and repertoire changes drive the functional improvement of HIV-specific CD8 T cell populations under conditions of limited antigenic stimulation. The Journal of Immunology 188 (3), pp.1156-1167. (10.4049/jimmunol.1102610)
• Wooldridge, L. et al. 2012. A single autoimmune T cell receptor recognizes more than a million different peptides. Journal of Biological Chemistry 287 (2), pp.1168-1177. (10.1074/jbc.M111.289488)
• Bridgeman, J. S. et al. 2012. Structural and biophysical determinants of ab T-cell antigen recognition. Immunology 135 (1), pp.9-18. (10.1111/j.1365-2567.2011.03515.x)
• Budde, M. L. et al., 2012. Specific CD8+ T cell responses correlate with control of simian immunodeficiency virus replication in Mauritian cynomolgus macaques. Journal of Virology 86 (14), pp.7596-7604. (10.1128/JVI.00716-12)
• Budimir, N. et al., 2012. Induction of heterosubtypic cross-protection against influenza by a whole inactivated virus vaccine: the role of viral membrane fusion activity. PLoS ONE 7 (1), pp.e30898. (10.1371/journal.pone.0030898)
• Bulek, A. M. et al. 2012. Structural basis for the killing of human beta cells by CD8+ T cells in type 1 diabetes. Nature Immunology 13 (3), pp.283-289. (10.1038/ni.2206)
• Chattopadhyay, P. K. et al., 2012. Brilliant violet fluorophores: A new class of ultrabright fluorescent compounds for immunofluorescence experiments. Cytometry Part A 81A (6), pp.456-466. (10.1002/cyto.a.22043)
• Doherty, T. M. et al., 2012. A T Cell-inducing influenza vaccine for the elderly: safety and immunogenicity of MVA-NP+M1 in adults aged over 50 years. PLoS ONE 7 (10) e48322. (10.1371/journal.pone.0048322)
• Humphreys, I. R. et al. 2012. Avidity of influenza-specific memory CD8+T-cell populations decays over time compromising antiviral immunity. European Journal of Immunology 42 (12), pp.3235-3242. (10.1002/eji.201242575)
• Lugli, E. et al., 2012. Identification, isolation and in vitro expansion of human and nonhuman primate T stem cell memory cell. Nature Protocols 8 (1), pp.33-42. (10.1038/nprot.2012.143)
• Maloveste, S. M. et al., 2012. Degenerate recognition of MHC class I molecules with Bw4 and Bw6 motifs by a killer cell Ig-like receptor 3DL expressed by macaque NK cells. The Journal of Immunology 189 (9), pp.4338-4348. (10.4049/jimmunol.1201360)
• Mendoza, D. et al., 2012. HLA B*5701-positive long-term nonprogressors/elite controllers are not distinguished from progressors by the clonal composition of HIV-specific CD8+ T cells. Journal of Virology 86 (7), pp.4014-4018. (10.1128/JVI.06982-11)
• Walker, C. M. et al., 2012. Rapid antigen processing and presentation of a protective and immunodominant HLA-B*27-restricted Hepatitis C virus-specific CD8+ T-cell epitope. PLoS Pathogens 8 (11) e1003042. (10.1371/journal.ppat.1003042)
• Yamamoto, T. et al., 2012. Virus inhibition activity of effector memory CD8+ T cells determines simian immunodeficiency virus load in vaccinated monkeys after vaccine breakthrough infection. Journal of Virology 86 (10), pp.5877-5884. (10.1128/JVI.00315-12)

2011

• Wu, Y. et al., 2011. Structural basis of diverse peptide accommodation by the rhesus macaque MHC class I molecule Mamu-B*17: insights into immune protection from simian immunodeficiency virus. The Journal of Immunology 187 (12), pp.6382-6392. (10.4049/jimmunol.1101726)
• Vivian, J. P. et al., 2011. Killer cell immunoglobulin-like receptor 3DL1-mediated recognition of human leukocyte antigen B [Letter]. Nature 479 (7373), pp.401-405. (10.1038/nature10517)
• Gattinoni, L. et al., 2011. A human memory T cell subset with stem cell-like properties. Nature Medicine 17 (10), pp.1290-1297. (10.1038/nm.2446)
• Quigley, M. F. et al., 2011. Unbiased molecular analysis of T cell receptor expression using template-switch achored RT-PCR. Current Protocols in Immunology 94:VII:10.33:10.33.1–10.33.16.. (10.1002/0471142735.im1033s94)
• Clement, M. et al. 2011. Anti-CD8 antibodies can trigger CD8+ T cell effector function in the absence of TCR engagement and improve peptide-MHCI tetramer staining. The Journal of Immunology 187 (2), pp.654-663. (10.4049/jimmunol.1003941)
• Haney, D. et al., 2011. Isolation of viable antigen-specific CD8+ T cells based on membrane-bound tumor necrosis factor (TNF)-α expression. Journal of Immunological Methods 369 (1-2), pp.33-41. (10.1016/j.jim.2011.04.003)
• Burwitz, B. J. et al., 2011. Simian immunodeficiency virus SIVmac239 nef vaccination elicits different tat28-35SL8-specific CD8+ T-cell clonotypes compared to a DNA prime/adenovirus type 5 boost regimen in rhesus macaques. Journal of Virology 85 (7), pp.3683-3689. (10.1128/JVI.02112-10)
• Nagai, K. et al., 2011. Aurora kinase A-specific T-cell receptor gene transfer redirects T lymphocytes to display effective antileukemia reactivity. Blood 119 (2), pp.368-376. (10.1182/blood-2011-06-360354)
• Minassian, A. M. et al., 2011. A phase I study evaluating the safety and immunogenicity of MVA85A, a candidate TB vaccine, in HIV-infected adults. BMJ Open 1 (2), pp.e000223. (10.1136/bmjopen-2011-000223)
• Berger, C. T. et al., 2011. High-functional-avidity cytotoxic T lymphocyte responses to HLA-B-restricted gag-derived epitopes associated with relative HIV control. Journal of Virology 85 (18), pp.9334-9345. (10.1128/JVI.00460-11)
• Falkenburg, W. J. J. et al., 2011. Allogeneic HLA-A*02-restricted WT1-specific T cells from mismatched donors are highly reactive but show off-target promiscuity. The Journal of Immunology 187 (5), pp.2824-2833. (10.4049/jimmunol.1100852)
• Hindley, J. P. et al. 2011. Analysis of the T-cell receptor repertoires of tumor-infiltrating conventional and regulatory T cells reveals no evidence for conversion in carcinogen-induced tumors. Cancer Research 71 (3), pp.736-746. (10.1158/0008-5472.CAN-10-1797)
• Iglesias, M. C. et al., 2011. Escape from highly effective public CD8+ T-cell clonotypes by HIV. Blood 118 (8), pp.2138-2149. (10.1182/blood-2011-01-328781)
• Kreutzman, A. et al., 2011. Expansion of highly differentiated CD8+ T-cells or NK-cells in patients treated with dasatinib is associated with cytomegalovirus reactivation. Leukemia 25 (10), pp.1587-1597. (10.1038/leu.2011.135)
• Laugel, B. F. et al. 2011. The multiple roles of the CD8 coreceptor in T cell biology: opportunities for the selective modulation of self-reactive cytotoxic T cells. Journal of Leukocyte Biology 90 (6), pp.1089-1099. (10.1189/jlb.0611316)
• Miles, J. J. , Douek, D. C. and Price, D. 2011. Bias in the αβ T-cell repertoire: implications for disease pathogenesis and vaccination. Immunology and Cell Biology 89 (3), pp.375-387. (10.1038/icb.2010.139)
• O'Connor, S. L. et al., 2011. Conditional CD8+ T cell escape during acute simian immunodeficiency virus infection. Journal of Virology 86 (1), pp.605-609. (10.1128/JVI.05511-11)
• Ruckwardt, T. J. et al., 2011. Neonatal cd8 t-cell hierarchy is distinct from adults and is influenced by intrinsic t cell properties in respiratory syncytial virus infected mice. PLoS Pathogens 7 (12) e1002377. (10.1371/journal.ppat.1002377)
• Schmidt, J. et al., 2011. Immunodominance of HLA-A2-restricted hepatitis C virus-specific CD8+ T cell responses is linked to naive-precursor frequency. Journal of Virology 85 (10), pp.5232-5236. (10.1128/JVI.00093-11)
• Sloand, E. M. et al., 2011. T-cell immune responses to Wilms tumor 1 protein in myelodysplasia responsive to immunosuppressive therapy. Blood 117 (9), pp.2691-2699. (10.1182/blood-2010-04-277921)
• Venturi, V. et al., 2011. A mechanism for TCR sharing between T cell subsets and individuals revealed by pyrosequencing. The Journal of Immunology 186 (7), pp.4285-4294. (10.4049/jimmunol.1003898)
• Vojnov, L. et al., 2011. GagCM9-specific CD8+ T cells expressing limited public TCR clonotypes do not suppress SIV replication in vivo. PLoS ONE 6 (8) e23515. (10.1371/journal.pone.0023515)
• Yamamoto, T. et al., 2011. Surface expression patterns of negative regulatory molecules identify determinants of virus-specific CD8+ T-cell exhaustion in HIV infection. Blood 117 (18), pp.4805-4815. (10.1182/blood-2010-11-317297)

2010

• van Bockel, D. J. et al., 2010. Persistent survival of prevalent clonotypes within an immunodominant HIV gag-specific CD8+ T cell response. The Journal of Immunology 186 (1), pp.359-371. (10.4049/jimmunol.1001807)
• Jones, M. et al., 2010. IL-10 restricts memory T cell inflation during cytomegalovirus infection. The Journal of Immunology 185 (6), pp.3583-3592. (10.4049/jimmunol.1001535)
• Cole, D. et al. 2010. Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T cell recognition. The Journal of Immunology 185 (4), pp.2600-2610. (10.4049/jimmunol.1000629)
• Rosario, M. et al., 2010. Long peptides induce polyfunctional T cells against conserved regions of HIV-1 with superior breadth to single-gene vaccines in macaques. European Journal of Immunology 40 (7), pp.1973-1984. (http://dx.doi.org/10.1002/eji.201040344)
• Greene, J. M. et al., 2010. Extralymphoid CD8+ T cells resident in tissue from simian immunodeficiency virus SIVmac239 nef-vaccinated macaques suppress SIVmac239 replication ex vivo. Journal of Virology 84 (7), pp.3362-3372. (10.1128/JVI.02028-09)
• Wooldridge, L. et al. 2010. CD8 controls T cell cross-reactivity. The Journal of Immunology 185 (8), pp.4625-4632. (10.4049/jimmunol.1001480)
• Chattopadhyay, P. K. , Roederer, M. and Price, D. A. 2010. OMIP-002: Phenotypic analysis of specific human CD8+ T-cells using peptide-MHC class I multimers for any of four epitopes. Cytometry Part A 77A (9), pp.821-822. (10.1002/cyto.a.20945)
• Giannopoulos, K. et al., 2010. Peptide vaccination elicits leukemia-associated antigen-specific cytotoxic CD8+ T-cell responses in patients with chronic lymphocytic leukemia. Leukemia 24 (4), pp.798-805. (10.1038/leu.2010.29)
• Harris, L. D. et al., 2010. Mechanisms underlying γδ T-cell subset perturbations in SIV-infected Asian rhesus macaques. Blood 116 (20), pp.4148-4157. (10.1182/blood-2010-05-283549)
• Humphreys, I. R. et al. 2010. Biphasic role of 4-1BB in the regulation of mouse cytomegalovirus-specific CD8+ T cells. European Journal of Immunology 40 (10), pp.2762-2768. (10.1002/eji.200940256)
• Melenhorst, J. J. et al., 2010. Allogeneic virus-specific T cells with HLA alloreactivity do not produce GVHD in human subjects. Blood 116 (22), pp.4700-4702. (10.1182/blood-2010-06-289991)
• Miles, J. J. et al. 2010. Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus infection. PLoS Pathogens 6 (11) e1001198. (10.1371/journal.ppat.1001198)
• Quigley, M. F. et al., 2010. Convergent recombination shapes the clonotypic landscape of the naive T-cell repertoire. Proceedings of the National Academy of Sciences of the United States of America 107 (45), pp.19414-19419. (10.1073/pnas.1010586107)
• Rosario, M. et al., 2010. Novel recombinant mycobacterium bovis BCG, ovine atadenovirus, and modified vaccinia virus ankara vaccines combine to induce robust human immunodeficiency virus-specific CD4 and CD8 T-cell responses in rhesus macaques. Journal of Virology 84 (12), pp.5898-5908. (10.1128/JVI.02607-09)
• Schaubert, K. L. et al., 2010. Generation of robust CD8+ T-cell responses against subdominant epitopes in conserved regions of HIV-1 by repertoire mining with mimotopes. European Journal of Immunology 40 (7), pp.1950-1962. (10.1002/eji.200940079)
• Subramanya, S. et al., 2010. Enhanced induction of HIV-specific Cytotoxic T Lymphocytes by Dendritic cell-targeted delivery of SOCS-1 siRNA. Molecular Therapy 18 (11), pp.2028-2037. (10.1038/mt.2010.148)
• Van Tendeloo, V. F. et al., 2010. Induction of complete and molecular remissions in acute myeloid leukemia by Wilms' tumor 1 antigen-targeted dendritic cell vaccination. Proceedings of the National Academy of Sciences of the United States of America 107 (31), pp.13824-13829. (10.1073/pnas.1008051107)
• Wooldridge, L. et al. 2010. MHC Class I molecules with superenhanced CD8 binding properties bypass the requirement for cognate TCR recognition and nonspecifically activate CTLs. Journal of Immunology 184 (7), pp.3357-3366. (10.4049/jimmunol.0902398)

2009

• Burwitz, B. J. et al., 2009. P20-16. Ultra-deep pyrosequencing detects complex patterns of CD8+ T-lymphocyte escape in SIV-infected macaques. Retrovirology 6 (S3) P386. (10.1186/1742-4690-6-S3-P386)
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• Bimber, B. N. et al., 2009. Ultradeep pyrosequencing detects complex patterns of CD8+ T-lymphocyte escape in simian immunodeficiency virus-infected macaques. Journal of Virology 83 (16), pp.8247-8253. (10.1128/JVI.00897-09)
• Lissina, A. et al., 2009. Protein kinase inhibitors substantially improve the physical detection of T-cells with peptide-MHC tetramers. Journal of Immunological Methods 340 (1), pp.11-24. (10.1016/j.jim.2008.09.014)
• Almeida, J. et al., 2009. P16-17. Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV suppressive activity. Retrovirology 6 (3) P246. (10.1186/1742-4690-6-S3-P246)
• Almeida, J. R. et al., 2009. Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity. Blood 113 (25), pp.6351-6360. (10.1182/blood-2009-02-206557)
• Chattopadhyay, P. K. et al., 2009. The cytolytic enzymes granyzme A, granzyme B, and perforin: expression patterns, cell distribution, and their relationship to cell maturity and bright CD57 expression. Journal of Leukocyte Biology 85 (1), pp.88-97. (10.1189/jlb.0208107)
• Cole, D. et al. 2009. Germ line-governed recognition of a cancer epitope by an immunodominant human T-cell receptor. Journal of Biological Chemistry 284 (40) 27281-27289. (10.1074/jbc.M109.022509)
• Geldmacher, C. et al., 2009. Minor viral and host genetic polymorphisms can dramatically impact the biologic outcome of an epitope-specific CD8 T-cell response. Blood 114 (8), pp.1553-1562. (10.1182/blood-2009-02-206193)
• Greenaway, H. Y. et al., 2009. Extraction and characterization of the rhesus macaque T-cell receptor β-chain genes. Immunology and Cell Biology 87 (7), pp.546-553. (10.1038/icb.2009.38)
• Honda, M. et al., 2009. Different vaccine vectors delivering the same antigen elicit CD8+ T cell responses with distinct clonotype and epitope specificity. The Journal of Immunology 183 (4), pp.2425-2434. (10.4049/jimmunol.0900581)
• Nakamoto, N. et al., 2009. Synergistic reversal of intrahepatic hcv-specific cd8 t cell exhaustion by combined pd-1/ctla-4 blockade. PLoS Pathogens 5 (2) e1000313. (10.1371/journal.ppat.1000313)
• Petrovas, C. et al., 2009. Differential association of programmed death-1 and CD57 with ex vivo survival of CD8+ T cells in HIV infection. The Journal of Immunology 183 (2), pp.1120-1132. (10.4049/jimmunol.0900182)
• Price, D. A. et al. 2009. Public clonotype usage identifies protective Gag-specific CD8+ T cell responses in SIV infection. Journal of Experimental Medicine 206 (4), pp.923-936. (10.1084/jem.20081127)
• Scheinberg, P. et al., 2009. The transfer of adaptive immunity to CMV during hematopoietic stem cell transplantation is dependent on the specificity and phenotype of CMV-specific T cells in the donor. Blood 114 (24), pp.5071-5080. (10.1182/blood-2009-04-214684)
• Wooldridge, L. et al. 2009. Tricks with tetramers: how to get the most from multimeric peptide-MHC. Immunology 126 (2), pp.147-164. (10.1111/j.1365-2567.2008.02848.x)

2008

• Venturi, V. et al., 2008. TCR β-Chain sharing in human CD8+ T cell responses to cytomegalovirus and EBV. Journal of Immunology 181 (11), pp.7853-7862. (10.4049/​jimmunol.181.11.7853)
• Melenhorst, J. J. et al., 2008. Detection of low avidity CD8+ T cell populations with coreceptor-enhanced peptide-major histocompatibility complex class I tetramers. Journal of Immunological Methods 338 (1-2), pp.31-39. (10.1016/j.jim.2008.07.008)
• Ebinuma, H. et al., 2008. Identification and in vitro expansion of functional antigen-specific CD25+ FoxP3+ regulatory T cells in hepatitis C virus infection. Journal of Virology 82 (10), pp.5043-5053. (10.1128/JVI.01548-07)
• Rehr, M. et al., 2008. Emergence of polyfunctional CD8+ T cells after prolonged suppression of human immunodeficiency virus replication by antiretroviral therapy. Journal of Virology 82 (7), pp.3391-3404. (10.1128/JVI.02383-07)
• Appay, V. , Douek, D. C. and Price, D. 2008. CD8+ T cell efficacy in vaccination and disease. Nature Medicine 14 (6), pp.623-628. (10.1038/nm.f.1774)
• Brenchley, J. M. et al., 2008. High frequencies of polyfunctional HIV-specific T cells are associated with preservation of mucosal CD4 T cells in bronchoalveolar lavage. Mucosal Immunology 1 (1), pp.49-58. (10.1038/mi.2007.5)
• Brenchley, J. M. et al., 2008. Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections. Blood 112 (7), pp.2826-2835. (10.1182/blood-2008-05-159301)
• Chattopadhyay, P. K. et al., 2008. Techniques to improve the direct ex vivo detection of low frequency antigen-specific CD8+T cells with peptide-major histocompatibility complex class I tetramers. Cytometry Part A 73A (11), pp.1001-1009. (10.1002/cyto.a.20642)
• Daucher, M. et al., 2008. Virological outcome after structured interruption of antiretroviral therapy for human immunodeficiency virus infection is associated with the functional profile of virus-specific CD8+ T cells. Journal of Virology 82 (8), pp.4102-4114. (10.1128/JVI.02212-07)
• Hestvik, A. L. K. et al., 2008. Multiple sclerosis: glatiramer acetate induces anti-inflammatory T cells in the cerebrospinal fluid. Multiple Sclerosis Journal 14 (6), pp.749-758. (10.1177/1352458508089411)
• Melenhorst, J. J. et al., 2008. Contribution of TCR- locus and HLA to the shape of the mature human V repertoire. The Journal of Immunology 180 (10), pp.6484-6489. (10.4049/jimmunol.180.10.6484)
• Melenhorst, J. J. et al., 2008. Contribution of TCR-beta locus and HLA to the shape of the mature human Vbeta repertoire. Journal of Immunology 180 (10), pp.6484-6489.
• Melenhorst, J. et al., 2008. Regulatory T-cell depletion does not prevent emergence of new CD25+ FOXP3+ lymphocytes after antigen stimulation in culture. Cytotherapy 10 (2), pp.152-164. (10.1080/14653240701853536)
• Mielke, S. et al., 2008. A clinical-scale selective allodepletion approach for the treatment of HLA-mismatched and matched donor-recipient pairs using expanded T lymphocytes as antigen-presenting cells and a TH9402-based photodepletion technique. Blood 111 (8), pp.4392-4402. (10.1182/blood-2007-08-104471)
• Nakamoto, N. et al., 2008. Functional restoration of HCV-specific CD8 T Cells by PD-1 blockade is defined by PD-1 expression and compartmentalization. Gastroenterology 134 (7), pp.1927-1937. (10.1053/j.gastro.2008.02.033)
• Price, D. et al. 2008. Induction and evolution of cytomegalovirus-specific CD4+ T cell clonotypes in rhesus macaques. Journal of Immunology 180 (1), pp.269-280. (10.4049/jimmunol.180.1.269)
• Reynolds, M. R. et al., 2008. Macaques vaccinated with live-attenuated SIV control replication of heterologous virus. Journal of Experimental Medicine 205 (11), pp.2537-2550. (10.1084/jem.20081524)
• Seggewiss, R. , Price, D. and Purbhoo, M. 2008. Immunomodulatory effects of imatinib and second-generation tyrosine kinase inhibitors on T cells and dendritic cells: an update. Cytotherapy 10 (6), pp.633-641. (10.1080/14653240802317639)
• Smith, M. Z. et al., 2008. Limited maintenance of vaccine-induced simian immunodeficiency virus-specific CD8 T-cell receptor clonotypes after virus challenge. Journal of Virology 82 (15), pp.7357-7368. (10.1128/JVI.00607-08)
• Venturi, V. et al., 2008. The role of production frequency in the sharing of simian immunodeficiency virus-specific CD8+ TCRs between macaques. Journal of Immunology 181 (4), pp.2597-2609. (10.4049/jimmunol.181.4.2597)
• Venturi, V. et al., 2008. The molecular basis for public T-cell responses?. Nature Reviews Immunology 8 (3), pp.231-238. (10.1038/nri2260)
• Weichsel, R. et al., 2008. Profound inhibition of antigen-specific T-cell effector functions by dasatinib. Clinical Cancer Research 14 (8), pp.2484-2491. (10.1158/1078-0432.CCR-07-4393)

2007

• Loffredo, J. T. et al., 2007. Cd8+ T cells from siv elite controller macaques recognize mamu-b*08-bound epitopes and select for widespread viral variation. PLoS ONE 2 (11) e1152. (10.1371/journal.pone.0001152)
• Laugel, B. F. et al. 2007. Different T cell receptor affinity thresholds and CD8 coreceptor dependence govern cytotxic T lymphocyte activation and tetramer properties. The Journal of Biological Chemistry 282 (33), pp.23799-22810. (10.1074/jbc.M700976200)
• Cole, D. et al. 2007. Human TCR-binding affinity is governed by MHC class restriction. The Journal of Immunology 178 (9), pp.5727-5734. (10.4049/​jimmunol.178.9.5727)
• Wooldridge, L. et al. 2007. Enhanced immunogenicity of CTL antigens through mutation of the CD8 binding MHC class I invariant region. European Journal of Immunology 37 (5), pp.1323-1333. (10.1002/eji.200636765)
• Scheinberg, P. et al., 2007. The clonal composition of human CD4+CD25+Foxp3+ cells determined by a comprehensive DNA-based multiplex PCR for TCRB gene rearrangements. Journal of Immunological Methods 321 (1-2), pp.107-120. (10.1016/j.jim.2007.01.005)
• Gostick, E. et al., 2007. Functional and biophysical characterization of an HLA-A*6801-restricted HIV-specific T cell receptor. European Journal of Immunology 37 (2), pp.479-486. (10.1002/eji.200636243)
• Almeida, J. R. et al., 2007. Superior control of HIV-1 replication by CD8+T cells is reflected by their avidity, polyfunctionality, and clonal turnover. Journal of Experimental Medicine 204 (10), pp.2473-2485. (10.1084/jem.20070784)
• Beveridge, N. et al. 2007. Immunisation with BCG and recombinant MVA85A induces long-lasting, polyfunctionalMycobacterium tuberculosis-specific CD4+ memory T lymphocyte populations. European Journal of Immunology 37 (11), pp.3089-3100. (10.1002/eji.200737504)
• Davenport, M. , Price, D. and McMichael, A. 2007. The T cell repertoire in infection and vaccination: implications for control of persistent viruses. Current Opinion in Immunology 19 (3), pp.294-300. (10.1016/j.coi.2007.04.001)
• Hryniewicz, A. et al., 2007. Interleukin-15 but not interleukin-7 abrogates vaccine-induced decrease in virus level in simian immunodeficiency virusmac251-infected macaques. The Journal of Immunology 178 (6), pp.3492-3504. (10.4049/jimmunol.178.6.3492)
• Laugel, B. et al., 2007. CD8 exerts differential effects on the deployment of cytotoxic T lymphocyte effector functions. European Journal of Immunology 37 (4), pp.905-913. (10.1002/eji.200636718)
• Maness, N. J. et al., 2007. AIDS virus-specific CD8+T lymphocytes against an immunodominant cryptic epitope select for viral escape. Journal of Experimental Medicine 204 (11), pp.2505-2512. (10.1084/jem.20071261)
• Petrovas, C. et al., 2007. SIV-specific CD8+ T cells express high levels of PD1 and cytokines but have impaired proliferative capacity in acute and chronic SIVmac251 infection. Blood 110 (3), pp.928-936. (10.1182/blood-2007-01-069112)
• Precopio, M. L. et al., 2007. Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8+T cell responses. Journal of Experimental Medicine 204 (6), pp.1405. (10.1084/jem.20062363)
• Purbhoo, M. A. et al., 2007. The HLA A*0201-restricted hTERT540-548 peptide is not detected on tumor cells by a CTL clone or a high-affinity T-cell receptor. Molecular Cancer Therapeutics 6 (7), pp.2081-2091. (10.1158/1535-7163.MCT-07-0092)
• Rezvani, K. et al., 2007. Graft-versus-leukemia effects associated with detectable Wilms tumor-1-specific T lymphocytes after allogeneic stem-cell transplantation for acute lymphoblastic leukemia. Blood 110 (6), pp.1924-1932. (10.1182/blood-2007-03-076844)
• Schaubert, K. L. et al., 2007. Availability of a diversely Avid CD8+ T cell repertoire specific for the subdominant HLA-A2-restricted HIV-1 gag p2419-27 epitope. The Journal of Immunology 178 (12), pp.7756-7766. (10.4049/jimmunol.178.12.7756)
• van Bockel, D. et al., 2007. Validation of RNA-based molecular clonotype analysis for virus-specific CD8+ T-cells in formaldehyde-fixed specimens isolated from peripheral blood. Journal of Immunological Methods 326 (1-2), pp.127-138. (10.1016/j.jim.2007.07.016)
• Yuan, F. et al., 2007. Crystallization and preliminary X-ray structural studies of a Melan-A pMHC-TCR complex. Acta Crystallographica Section F: Structural Biology and Crystallization Communications 63 (9), pp.758-760. (10.1107/S1744309107037244)

2006

• Price, D. et al. 2006. Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nature Medicine 12 (12), pp.1365-71. (10.1038/nm1511)
• Chattopadhyay, P. K. et al., 2006. Quantum dot semiconductor nanocrystals for immunophenotyping by polychomatic flow cytometry. Nature Medicine 12 (8), pp.972-7. (10.1038/nm1371)
• Wooldridge, L. et al. 2006. Anti-coreceptor antibodies profoundly affect staining with peptide-MHC class I and class II tetramers. European Journal of Immunology 36 (7), pp.1847-1855. (10.1002/eji.200635886)
• Brenchley, J. M. et al., 2006. Preferential infection shortens the life span of human immunodeficiency virus-specific CD4+ T cells in vivo. Journal of Virology 80 (14), pp.6801-6809. (10.1128/JVI.00070-06)
• Brenchley, J. M. , Price, D. and Douek, D. C. 2006. HIV disease: fallout from a mucosal catastrophe?. Nature Immunology 7 (3), pp.235-239. (10.1038/ni1316)
• Casazza, J. P. et al., 2006. Acquisition of direct antiviral effector functions by CMV-specific CD4+T lymphocytes with cellular maturation. Journal of Experimental Medicine 203 (13), pp.2865-2877. (10.1084/jem.20052246)
• Kan-Mitchell, J. et al., 2006. Degeneracy and repertoire of the Human HIV-1 Gag p1777-85 CTL Response. The Journal of Immunology 176 (11), pp.6690-6701. (10.4049/jimmunol.176.11.6690)
• Laugel, B. , Price, D. and Sewell, A. K. 2006. On the path to TCR-directed therapeutics. Nature Biotechnology 24 (6), pp.615-616. (10.1038/nbt0606-615b)
• Leslie, A. et al., 2006. Differential selection pressure exerted on HIV by CTL targeting identical epitopes but restricted by distinct HLA alleles from the same HLA supertype. The Journal of Immunology 177 (7), pp.4699-4708. (10.4049/jimmunol.177.7.4699)
• Petrovas, C. et al., 2006. PD-1 is a regulator of virus-specific CD8+T cell survival in HIV infection. Journal of Experimental Medicine 203 (10), pp.2281-2292. (10.1084/jem.20061496)
• Scheinberg, P. et al., 2006. Alloreactive T cell clonotype recruitment in a mixed lymphocyte reaction: Implications for graft engineering. Experimental Hematology 34 (6), pp.788-795. (10.1016/j.exphem.2006.03.001)
• Venturi, V. et al., 2006. Sharing of T cell receptors in antigen-specific responses is driven by convergent recombination. Proceedings of the National Academy of Sciences of the United States of America 103 (49), pp.18691-18696. (10.1073/pnas.0608907103)

2005

• Price, D. et al. 2005. Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA viruses. Journal of Experimental Medicine 202 (10), pp.1349-61. (10.1084/jem.20051357)
• Wooldridge, L. et al. 2005. Interaction between the CD8 coreceptor and major histocompatibility complex class I stabilizes T cell receptor-antigen complexes at the cell surface. The Journal of Biological Chemistry 280 (30), pp.27491-27501. (10.1074/jbc.M500555200)
• Laugel, B. et al., 2005. Design of soluble recombinant T Cell receptors for antigen targeting and T cell inhibition. Journal of Biological Chemistry 280 (3), pp.1882-1892. (10.1074/jbc.M409427200)
• Betts, M. R. et al., 2005. Characterization of functional and phenotypic changes in anti-Gag vaccine-induced T cell responses and their role in protection after HIV-1 infection. Proceedings of the National Academy of Sciences of the United States of America 102 (12), pp.4512-4517. (10.1073/pnas.0408773102)
• Casazza, J. P. et al., 2005. Immunologic pressure within class I-restricted cognate human immunodeficiency virus epitopes during highly active antiretroviral therapy. Journal of Virology 79 (6), pp.3653-3663. (10.1128/JVI.79.6.3653-3663.2005)
• Ellmerich, S. et al., 2005. High incidence of spontaneous disease in an HLA-DR15 and TCR transgenic multiple sclerosis model. The Journal of Immunology 174 (4), pp.1938-1946. (10.4049/jimmunol.174.4.1938)
• Fujiwara, H. et al., 2005. In vitro induction of myeloid leukemia-specific CD4 and CD8 T cells by CD40 ligand-activated B cells gene modified to express primary granule proteins. Clinical Cancer Research 11 (12), pp.4495-4503. (10.1158/1078-0432.CCR-04-2363)
• Hewitt, R. E. et al., 2005. The bisphosphonate acute phase response: rapid and copious production of proinflammatory cytokines by peripheral blood gd T cells in response to aminobisphosphonates is inhibited by statins. Clinical and Experimental Immunology 139 (1), pp.101-111. (10.1111/j.1365-2249.2005.02665.x)
• Joos, B. et al., 2005. Low human immunodeficiency virus envelope diversity correlates with low in vitro replication capacity and predicts spontaneous control of plasma viremia after treatment interruptions. Journal of Virology 79 (14), pp.9026-9037. (10.1128/JVI.79.14.9026-9037.2005)
• Milicic, A. et al., 2005. CD8+ T cell epitope-flanking mutations disrupt proteasomal processing of HIV-1 Nef. The Journal of Immunology 175 (7), pp.4618-4626. (10.4049/jimmunol.175.7.4618)
• Rezvani, K. et al., 2005. T-cell responses directed against multiple HLA-A*0201-restricted epitopes derived from Wilms' tumor 1 protein in patients with leukemia and healthy donors: identification, quantification, and characterization.. Clinical Cancer Research 11 (24), pp.8799-8807. (10.1158/1078-0432.CCR-05-1314)
• Seggewiss, R. et al., 2005. Imatinib inhibits T-cell receptor-mediated T-cell proliferation and activation in a dose-dependent manner. Blood 105 (6), pp.2473-2479. (10.1182/blood-2004-07-2527)

2004

• Price, D. et al. 2004. T cell receptor recognition motifs govern immune escape patterns in acute SIV infection. Immunity 21 (6), pp.793-803. (10.1016/j.immuni.2004.10.010)
• Betts, M. R. et al., 2004. The functional profile of primary human antiviral CD8+ T cell effector activity is dictated by cognate peptide concentration. The Journal of Immunology 172 (10), pp.6407-6417. (10.4049/jimmunol.172.10.6407)
• Brenchley, J. M. et al., 2004. T-cell subsets that harbor human immunodeficiency virus (HIV) in vivo: implications for HIV pathogenesis. Journal of Virology 78 (3), pp.1160-1168. (10.1128/JVI.78.3.1160-1168.2004)
• Brenchley, J. M. et al., 2004. CD4+T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract. Journal of Experimental Medicine 200 (6), pp.749-759. (10.1084/jem.20040874)
• Crawford, M. P. et al., 2004. High prevalence of autoreactive, neuroantigen-specific CD8+ T cells in multiple sclerosis revealed by novel flow cytometric assay. Blood 103 (11), pp.4222-4231. (10.1182/blood-2003-11-4025)
• Fujiwara, H. et al., 2004. Identification and in vitro expansion of CD4+ and CD8+ T cells specific for human neutrophil elastase. Blood 103 (8), pp.3076-3083. (10.1182/blood-2003-07-2424)
• Green, A. E. et al., 2004. Recognition of nonpeptide antigens by human Vγ9Vδ2 T cells requires contact with cells of human origin. Clinical & Experimental Immunology 136 (3), pp.472-482. (10.1111/j.1365-2249.2004.02472.x)
• Oxenius, A. et al., 2004. HIV-specific cellular immune response is inversely correlated with disease progression as defined by decline of CD4+T cells in relation to HIV RNA load. International Journal of Infectious Diseases 189 (7), pp.1199-1208. (10.1086/382028)
• Oxenius, A. et al., 2004. Loss of viral control in early HIV-1 infection Is temporally associated with sequential escape from CD8+ T cell responses and decrease in HIV-1-specific CD4+ and CD8+ T cell frequencies. International Journal of Infectious Diseases 190 (4), pp.713-721. (10.1086/422760)
• Scherer, A. et al., 2004. Quantifiable cytotoxic T lymphocyte responses and HLA-related risk of progression to AIDS. Proceedings of the National Academy of Sciences of the United States of America 101 (33), pp.12266-12270. (10.1073/pnas.0404091101)

2003

• Wooldridge, L. et al. 2003. Anti-CD8 antibodies can inhibit or enhance peptide-MHC class I (pMHCI) multimer binding: this is paralleled by their effects on CTL activation and occurs in the absence of an interaction between pMHCI and CD8 on the cell surface. J Immunol 171 , pp.6650-60.
• Jones, E. et al., 2003. The influence of macrophage inflammatory protein-1alpha on protective immunity mediated by antiviral cytotoxic T cells. Immunology 109 (1), pp.68-75. (10.1046/j.1365-2567.2003.01636.x)
• Betts, M. R. et al., 2003. Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation. Journal of Immunological Methods 281 (1-2), pp.65-78. (10.1016/S0022-1759(03)00265-5)
• Brookes, R. H. et al., 2003. CD8+ T cell-mediated suppression of intracellularMycobacterium tuberculosis growth in activated human macrophages. European Journal of Immunology 33 (12), pp.3293-3302. (10.1002/eji.200324109)
• Fagard, C. et al., 2003. A prospective trial of structured treatment interruptions in human immunodeficiency virus infection. Archives of Internal Medicine 163 (10), pp.1220-1226. (10.1001/archinte.163.10.1220)
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• Price, D. et al. 2003. Discordant outcomes following failure of antiretroviral therapy are associated with substantial differences in human immunodeficiency virus-specific cellular immunity. Journal of Virology 77 (10), pp.6041-6049. (10.1128/JVI.77.10.6041-6049.2003)
• Rezvani, K. et al., 2003. Functional leukemia-associated antigen-specific memory CD8+ T cells exist in healthy individuals and in patients with chronic myelogenous leukemia before and after stem cell transplantation. Blood 102 (8), pp.2892-2900. (10.1182/blood-2003-01-0150)

2002

• Douek, D. C. et al., 2002. HIV preferentially infects HIV-specific CD4+ T cells. Nature 417 (6884), pp.95-98. (10.1038/417095a)
• Glick, M. et al., 2002. Novel CD8+ T cell antagonists based on 2-Microglobulin. Journal of Biological Chemistry 277 (23), pp.20840-20846. (10.1074/jbc.M201819200)
• Kelleher, A. D. , Sewell, A. K. and Price, D. 2002. Dyslipidemia due to retroviral protease inhibitors [Letter]. Nature Medicine 8 (4), pp.308. (10.1038/nm0402-308a)
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2001

• Altes, H. K. , Price, D. and Jansen, V. A. 2001. Effector cytotoxic T lymphocyte numbers induced by vaccination should exceed levels in chronic infection for protection from HIV. Vaccine 20 (1-2), pp.3-6. (10.1016/S0264-410X(01)00318-8)
• Oxenius, A. et al., 2001. Cross-staining of cytotoxic T lymphocyte populations with peptide-MHC class I multimers of natural HIV-1 variant antigens. AIDS 15 (1), pp.121-122. (10.1097/00002030-200101050-00018)
• Karadimitris, A. et al., 2001. Human CD1d-glycolipid tetramers generated by in vitro oxidative refolding chromatography. Proceedings of the National Academy of Sciences of the United States of America 98 (6), pp.3294-3298. (10.1073/pnas.051604498)
• Purbhoo, M. A. et al., 2001. The human CD8 coreceptor effects cytotoxic T cell activation and antigen sensitivity primarily by mediating complete phosphorylation of the T cell receptor chain. Journal of Biological Chemistry 276 (35), pp.32786-32792. (10.1074/jbc.M102498200)
• Sewell, A. K. and Price, D. 2001. Dendritic cells and transmission of HIV-1. Trends in Immunology 22 (4), pp.173-175. (10.1016/S1471-4906(01)01866-X)

2000

• Phillips, R. E. et al., 2000. AIDS: the evolving story. Trends in Microbiology 8 (4), pp.147-148. (10.1016/S0966-842X(00)01706-6)
• Oxenius, A. et al., 2000. Early highly active antiretroviral therapy for acute HIV-1 infection preserves immune function of CD8+ and CD4+ T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America 97 (7), pp.3382-3387. (10.1073/pnas.97.7.3382)

1999

• Price, D. et al. 1999. Cytotoxic T lymphocytes, chemokines and antiviral immunity. Immunology Today 20 (5), pp.212-216. (10.1016/S0167-5699(99)01447-4)
• Sewell, A. K. et al. 1999. Antagonism of cytotoxic T-lymphocyte activation by soluble CD8. Nature Medicine 5 , pp.399-404. (10.1038/7398)

1998

• Lewis, J. W. et al., 1998. HLA-A*0201 presents TAP-dependent peptide epitopes to cytotoxic T lymphocytes in the absence of tapasin. European Journal of Immunology 28 , pp.3214-3220.
• Price, D. et al. 1998. Antigen-specific release of b-chemokines by anti-HIV-1 cytotoxic T lymphocytes. Current Biology 8 (6), pp.355-358. (10.1016/S0960-9822(98)70138-1)

1997

• Sewell, A. K. et al. 1997. Antagonism of cytotoxic T lymphocyte-mediated lysis by natural HIV-1 altered peptide ligands requires simultaneous presentation of agonist and antagonist peptides. European Journal of Immunology 27 (9), pp.2323-2329. (10.1002/eji.1830270929)
• Goulder, P. J. R. et al., 1997. Combined structural and immunological refinement of HIV-1 HLA-B8-restricted cytotoxic T lymphocyte epitopes. European Journal of Immunology 27 (6), pp.1515-1521. (10.1002/eji.1830270630)
• Price, D. et al. 1997. Positive selection of HIV-1 cytotoxic T lymphocyte escape variants during primary infection. Proceedings of the National Academy of Sciences 94 (5), pp.1890-1895. (10.1073/pnas.94.5.1890)
• Goulder, P. et al., 1997. Co-evolution of human immunodeficiency virus and cytotoxic T-lymphocyte responses. Immunological Reviews 159 (1), pp.17-29. (10.1111/j.1600-065X.1997.tb01004.x)
• Goulder, P. et al., 1997. Patterns of immunodominance in HIV-1-specific cytotoxic T lymphocyte responses in two human histocompatibility leukocyte antigens (HLA)-identical siblings with HLA-A*0201 are influenced by epitope mutation. Journal of Experimental Medicine 185 (8), pp.1423-1433. (10.1084/jem.185.8.1423)

1995

• Teare, J. P. et al., 1995. Reversible AIDS-related sclerosing cholangitis. Journal of Hepatology 23 (2), pp.209-211. (10.1016/0168-8278(95)80337-8)

1994

• Price, D. et al. 1994. Clinical response to the addition of clarithromycin in Pneumocystis carinii pneumonia refractory to high dose co-trimoxazole. Journal of Antimicrobial Chemotherapy 34 (2), pp.303. (10.1093/jac/34.2.303)