![Lucy Riglin](https://profiles-cardiff.imgix.net/attachments/6390?w=200&h=200&auto=format&crop=faces&fit=crop&q=90")
Trosolwg
Rwy'n uwch ddarlithydd yng Nghanolfan Wolfson ar gyfer Iechyd Meddwl Pobl Ifanc ac rwy'n rhan o'r grŵp Seiciatreg Plant a'r Glasoed yn y Ganolfan Geneteg a Genomeg Niwroseiciatrig. Mae fy ymchwil yn ymchwilio i iechyd meddwl pobl ifanc gan ddefnyddio dull rhyngddisgyblaethol, gan integreiddio seicopatholeg ddatblygiadol, seiciatreg ac epidemioleg genetig. Mae gen i ddiddordeb arbennig mewn gwahaniaethau datblygiadol yn etioleg a chyflwyno problemau iechyd meddwl.
Yn 2023 dyfarnwyd Grant Ymchwil Ymchwilydd Newydd MRC i mi i ymchwilio i sut a pham mae ADHD yn arwain at iselder mewn pobl ifanc (2023-2027). Cynhelir yr ymchwil hon mewn cydweithrediad â phobl ifanc sydd â phrofiad byw trwy Grŵp Cynghori Ieuenctid Canolfan Wolfson a Sefydliad McPin.
Rwyf hefyd yn gyd-ymchwilydd ar brosiect Horizon Europe Youth-GEMs: Gene Environment interactions in Mental health trajectories of Youth (2022-2027).
Cyhoeddiad
2026
- Fury, B. et al., 2026. Investigating the associations between neurodevelopmental and psychiatric genetic liability and adverse social and functional outcomes across childhood, adolescence and young-adulthood. Molecular Psychiatry (10.1038/s41380-026-03903-x)
- Bekiropoulou, A. et al. 2026. Using a developmental approach to investigate behavioral, neurodevelopmental, and depressive irritability types. JAACAP Open 4 (3), pp.546-562. (10.1016/j.jaacop.2026.02.006)
- Padaigaitė-Gulbinienė, E. et al. 2026. Clinical and cognitive mediators underlying subsequent depression in individuals with attention-deficit/hyperactivity disorder: A developmental approach. Journal of the American Academy of Child & Adolescent Psychiatry (10.1016/j.jaac.2026.06.001)
- Weavers, B. et al. 2026. Heterogeneity in the longitudinal course of depressive symptomatology in adults with a history of recurrent major depressive disorder. Journal of Affective Disorders 403 121498. (10.1016/j.jad.2026.121498)
- Dennison, C. A. et al. 2026. Childhood ADHD and autism spectrum disorder difficulties: exploring the impact of copy number variants on young adult outcomes. BJPsych Open 12 (3) e108. (10.1192/bjo.2026.11018)
- Lewis, K. J. S. et al. 2026. A developmentally informed study of sleep and circadian polygenic scores in adolescence. JAMA Psychiatry 83 (5), pp.523-528. (10.1001/jamapsychiatry.2025.4647)
- Williams, G. et al. 2026. Investigating the symptom presentation of depression in children with ADHD. Journal of Attention Disorders 30 (4), pp.449-459. (10.1177/10870547251366783)
- Dennison, C. A. et al. 2026. The role of rare copy number variants in early‐onset depression. JCPP Advances e70128. (10.1002/jcv2.70128)
- Shakeshaft, A. et al. 2026. Mapping phenotypic and genetic relationships among irritability, depression and ADHD in adolescence using network analysis. Journal of Child Psychology and Psychiatry 67 (3), pp.333-343. jcpp.70040. (10.1111/jcpp.70040)
- Tseng, W. et al., 2026. Cross-Cultural Consortium on Irritability (C3I): An international network for research on cultural similarities and differences in irritability. JAACAP Open 4 (1), pp.184-197. (10.1016/j.jaacop.2025.09.001)
- Bekiropoulou, A. et al. 2026. Measuring irritability across childhood, adolescence, and young adulthood: an investigation of measurement invariance by age, sex, and informant. European Child and Adolescent Psychiatry 35 , pp.121-132. (10.1007/s00787-025-02817-3)
2025
- Dennison, C. A. et al. 2025. Early manifestations of neurodevelopmental copy number variants in children: A population-based investigation. Biological Psychiatry 98 (12), pp.924-933. (10.1016/j.biopsych.2025.03.004)
- Franklin, A. et al., 2025. Cell-type-specific DNA methylation dynamics in the prenatal and postnatal human cortex. Cell Genomics 5 (12) 101010. (10.1016/j.xgen.2025.101010)
- Padaigaitė-Gulbinienė, E. et al. 2025. Study preregistration: clinical and cognitive mediators underlying subsequent depression in individuals with attention-deficit/hyperactivity disorder: a developmental approach. Journal of the American Academy of Child & Adolescent Psychiatry 64 (11), pp.1329-1331. (10.1016/j.jaac.2025.03.023)
- Shakeshaft, A. et al. 2025. Investigating irritability as a potentially causal risk pathway into depression using two genetically informed designs. Biological Society: Global Open Science 5 (6) 100566. (10.1016/j.bpsgos.2025.100566)
- Barrass, L. et al., 2025. Intergenerational educational mobility and mental health: Evidence from a Filipino birth cohort. PLOS Global Public Health 5 (8) e0004570. (10.1371/journal.pgph.0004570)
- Armitage, J. et al. 2025. A cross-country comparison of temporal change in adolescent mental health problems in the UK and Brazil. Epidemiology and Psychiatric Sciences 34 e17. (10.1017/S2045796025000137)
2024
- Riglin, L. et al. 2024. Emotional problems across development: examining measurement invariance across childhood, adolescence and early adulthood. European Child and Adolescent Psychiatry 33 , pp.4237-4245. (10.1007/s00787-024-02461-3)
- Barrass, L. et al., 2024. The association between socioeconomic position and depression or suicidal ideation in low- and middle-income countries in Southeast Asia: a systematic review and meta-analysis. BMC Public Health 24 (1) 3507. (10.1186/s12889-024-20986-9)
- Wootton, R. et al., 2024. Testing maternal effects of vitamin-D and omega-3 levels on offspring neurodevelopmental traits in the Norwegian mother, father and child cohort study. Psychological Medicine 54 (12), pp.3323-3333. (10.1017/S0033291724001466)
- Reed, H. et al., 2024. The unequal impacts of the COVID-19 pandemic on young adults' mental health. Predictors of vulnerability and resilience using longitudinal birth cohort data in the UK. Journal of Adolescence (10.1002/jad.12400)
- Tseliou, F. et al. 2024. Childhood correlates and young adult outcomes of trajectories of emotional problems from childhood to adolescence. Psychological Medicine 54 (10), pp.2504-2514. (10.1017/S0033291724000631)
- Shakeshaft, A. et al. 2024. Estimating the impact of transmitted and non-transmitted psychiatric and neurodevelopmental polygenic scores on youth emotional problems. Molecular Psychiatry 29 , pp.238-246. (10.1038/s41380-023-02319-1)
- Shakeshaft, A. et al. 2024. Long-term physical health conditions and youth anxiety and depression: Is there a causal link?. Psychological Medicine 55 e7. (10.1017/S0033291724003271)
- Agha, S. S. et al., 2024. Young adult ADHD symptoms in the general population and neurocognitive impairment. Journal of Attention Disorders 28 (1), pp.89-98. (10.1177/10870547231201870)
- Dennison, C. et al. 2024. Stratifying early-onset emotional disorders: using genetics to assess persistence in young people of European and South Asian ancestry. Journal of Child Psychology and Psychiatry 65 (1), pp.42-51. (10.1111/jcpp.13862)
2023
- Shakeshaft, A. et al. 2023. Co-development of attention deficit hyperactivity disorder and autistic trait trajectories from childhood to early adulthood. Journal of Child Psychology and Psychiatry 64 (11), pp.1596-1607. (10.1111/jcpp.13851)
- Thapar, A. et al. 2023. Childhood attention deficit hyperactivity disorder problems and mid-life cardiovascular risk: a prospective population cohort study. The British Journal of Psychiatry 223 (4), pp.472-477. (10.1192/bjp.2023.90)
- Weavers, B. et al. 2023. Characterising depression trajectories in young people at high familial risk of depression. Journal of Affective Disorders 337 , pp.66-74. (10.1016/j.jad.2023.05.063)
- Langley, K. et al. 2023. Can a nation-wide e-cohort of ADHD and ASD in childhood be established using Welsh routinely available datasets?. BMJ Open 13 e071851. (10.1136/bmjopen-2023-071851)
- Armitage, J. M. et al. 2023. Validation of the Strengths and Difficulties Questionnaire (SDQ) emotional subscale in assessing depression and anxiety across development. PLoS ONE 18 (7) e0288882. (10.1371/journal.pone.0288882)
- Shakeshaft, A. et al. 2023. Mental-health before and during the COVID-19 pandemic in adults with neurodevelopmental disorders. Journal of Psychiatric Research 159 , pp.230-239. (10.1016/j.jpsychires.2023.01.029)
- Thapar, A. et al. 2023. Practitioner Review: Attention‐deficit hyperactivity disorder and autism spectrum disorder – the importance of depression. Journal of Child Psychology and Psychiatry 64 (1), pp.4-15. (10.1111/jcpp.13678)
- Riglin, L. et al. 2023. Young-adult social outcomes of Attention-Deficit/Hyperactivity Disorder. Journal of Clinical Psychiatry 84 (2) 14379. (10.4088/jcp.22m14379)
2022
- Riglin, L. and Stergiakouli, E. 2022. Mendelian randomisation studies of Attention Deficit Hyperactivity Disorder. JCPP Advances 2 (4) e12117. (10.1002/jcv2.12117)
- Sellers, R. et al. 2022. Using genetic designs to identify likely causal environmental contributions to psychopathology. Development and Psychopathology 34 (5), pp.1653-1665. (10.1017/S0954579422000906)
- Pat, N. et al., 2022. Longitudinally stable, brain-based predictive models mediate the relationships between childhood cognition and socio-demographic, psychological and genetic factors.. Human Brain Mapping 43 (18), pp.5520-5542. (10.1002/hbm.26027)
- Riglin, L. et al. 2022. Early manifestations of genetic liability for ADHD, autism and schizophrenia at ages 18 and 24 months. JCPP Advances 2 (3) e12093. (10.1002/jcv2.12093)
- Tobarra‐Sanchez, E. et al., 2022. Preschool development, temperament and genetic liability as early markers of childhood ADHD: A cohort study. JCPP Advances 2 (3) e12099. (10.1002/jcv2.12099)
- Havdahl, A. et al., 2022. Associations between pregnancy-related predisposing factors for offspring neurodevelopmental conditions and parental genetic liability to Attention-Deficit/Hyperactivity Disorder, Autism, and Schizophrenia: The Norwegian Mother, Father and Child Cohort Study (MoBa). JAMA Psychiatry 79 (8), pp.799-810. (10.1001/jamapsychiatry.2022.1728)
- Riglin, L. et al. 2022. “Late-onset” ADHD symptoms in young adulthood: is this the same as child-onset ADHD?. Journal of Attention Disorders 26 (10), pp.1271-1282. (10.1177/10870547211066486)
- Wootton, R. E. et al., 2022. Decline in attention-deficit hyperactivity disorder traits over the life course in the general population: trajectories across five population birth cohorts spanning ages 3 to 45 years. International Journal of Epidemiology 51 (3), pp.919-930. (10.1093/ije/dyac049)
- Pat, N. et al., 2022. Motivation and cognitive abilities as mediators between polygenic scores and psychopathology in children. Journal of the American Academy of Child and Adolescent Psychiatry 61 (6), pp.782-795. e3. (10.1016/j.jaac.2021.08.019)
- Niina, A. et al., 2022. Exploring ADHD symptoms and associated impairment across development. Journal of Attention Disorders 26 (6), pp.822-830. (10.1177/10870547211025612)
- Riglin, L. et al. 2022. Assessment of age-at-onset criterion for adult attention-deficit hyperactivity disorder. British Journal of Psychiatry 220 (2), pp.73-75. (10.1192/bjp.2021.122)
- Wimberley, T. et al., 2022. Early-life injuries and the development of attention-deficit/hyperactivity disorder. Journal of Clinical Psychiatry 83 (1) 21m14033. (10.4088/JCP.21m14033)
2021
- Dardani, C. et al., 2021. Is genetic liability to ADHD and ASD causally linked to educational attainment?. International Journal of Epidemiology 50 (6), pp.2011-2023. (10.1093/ije/dyab107)
- Eyre, O. et al. 2021. Validation of the short Mood and Feelings Questionnaire in young adulthood. Journal of Affective Disorders 294 , pp.883-888. (10.1016/j.jad.2021.07.090)
- Martin, J. et al. 2021. Sex differences in anxiety and depression in children with ADHD investigating genetic liability and comorbidity. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 186 (7), pp.412-422. (10.1002/ajmg.b.32842)
- Powell, V. et al. 2021. Investigating friendship difficulties in the pathway from ADHD to depressive symptoms. Can parent-child relationships compensate?. Research on Child and Adolescent Psychopathology 49 , pp.1031-1041. (10.1007/s10802-021-00798-w)
- Riglin, L. et al. 2021. ADHD and depression: investigating a causal explanation. Psychological Medicine 51 (11), pp.1890-1897. (10.1017/S0033291720000665)
- Riglin, L. et al. 2021. Variable emergence of Autism Spectrum Disorder symptoms from childhood to early adulthood. American Journal of Psychiatry 178 (8), pp.752-760. (10.1176/appi.ajp.2020.20071119)
- Riglin, L. et al. 2021. Investigating the validity of the strengths and difficulties questionnaire to assess ADHD in young adulthood. Psychiatry Research 301 113984. (10.1016/j.psychres.2021.113984)
- Leppert, B. et al., 2021. The effect of ADHD on physical health outcomes - a two-sample Mendelian randomization study. American Journal of Epidemiology 190 (6), pp.1047-1055. (10.1093/aje/kwaa273)
- Rice, F. et al. 2021. Pupil mental health, concerns and expectations about secondary school as predictors of adjustment across the transition to secondary school: A longitudinal multi-informant study. School Mental Health 13 , pp.279-298. (10.1007/s12310-021-09415-z)
- Riglin, L. et al. 2021. Investigating attention‐deficit hyperactivity disorder and autism spectrum disorder traits in the general population: What happens in adult life?. Journal of Child Psychology and Psychiatry 62 (4), pp.449-457. (10.1111/jcpp.13297)
2020
- Powell, V. et al. 2020. What explains the link between childhood ADHD and adolescent depression? Investigating the role of peer relationships and academic attainment. European Child and Adolescent Psychiatry 29 , pp.1581-1591. (10.1007/s00787-019-01463-w)
- Thapar, A. and Riglin, L. 2020. The importance of a developmental perspective in Psychiatry: what do recent genetic epidemiological findings show?. Molecular Psychiatry 25 , pp.1631-1639. (10.1038/s41380-020-0648-1)
- Riglin, L. et al. 2020. Using genetics to examine a general liability to childhood psychopathology. Behavior Genetics 50 , pp.213-220. (10.1007/s10519-019-09985-4)
- Wimberle, T. et al., 2020. Genetic liability to ADHD and substance use disorders in individuals with ADHD. Addiction 115 (7), pp.1368-1377. (10.1111/add.14910)
- Leppart, B. et al., 2020. A cross-disorder PRS-pheWAS of 5 major psychiatric disorders in UK Biobank. PLoS Genetics 16 (5) e1008185. (10.1371/journal.pgen.1008185)
- Addicoat, A. et al. 2020. Adult mood problems in children with neurodevelopmental problems: evidence from a prospective birth cohort followed to age 50. Social Psychiatry and Psychiatric Epidemiology 55 , pp.351-358. (10.1007/s00127-019-01727-5)
2019
- Ng-Knight, T. et al., 2019. 'Best friends forever'? Friendship stability across school transition and associations with mental health and educational attainment. British Journal of Educational Psychology 89 (4), pp.585-599. (10.1111/bjep.12246)
- Eyre, O. et al. 2019. Irritability in ADHD: association with later depression symptoms. European Child and Adolescent Psychiatry 28 (10), pp.1375-1384. (10.1007/s00787-019-01303-x)
- Riglin, L. et al. 2019. Identifying novel types of irritability using a developmental genetic approach. American Journal of Psychiatry 176 (8), pp.635-642. (10.1176/appi.ajp.2019.18101134)
- Leppert, B. et al., 2019. Association of maternal neurodevelopmental risk alleles with early-life exposures. JAMA Psychiatry 76 (8), pp.834-842. (10.1001/jamapsychiatry.2019.0774)
- Kendall, K. M. et al. 2019. Association of rare copy number variants with risk of depression. JAMA Psychiatry 76 (8), pp.818-825. (10.1001/jamapsychiatry.2019.0566)
- Rice, F. et al. 2019. Characterizing developmental trajectories and the role of neuropsychiatric genetic risk variants in early-onset depression. JAMA Psychiatry 76 (3), pp.306-313. (10.1001/jamapsychiatry.2018.3338)
- Richards, A. et al. 2019. Associations between schizophrenia genetic risk, anxiety disorders and manic/hypomanic episode in a New Zealand longitudinal population cohort study. British Journal of Psychiatry 214 (2), pp.96-102. (10.1192/bjp.2018.227)
- Rice, F. et al. 2019. Adolescent and adult differences in major depression symptom profiles. Journal of Affective Disorders 243 , pp.175-181. (10.1016/j.jad.2018.09.015)
- Riglin, L. et al. 2019. Developmental contributions of schizophrenia risk alleles and childhood peer victimization to early-onset mental health trajectories. American Journal of Psychiatry 176 (1), pp.36-43. (10.1176/appi.ajp.2018.18010075)
2018
- Cooper, M. et al. 2018. Investigating late-onset ADHD: a population cohort investigation. Journal of Child Psychology and Psychiatry 59 (10), pp.1105-1113. (10.1111/jcpp.12911)
- Riglin, L. et al. 2018. The impact of schizophrenia and mood disorder risk alleles on emotional problems: investigating change from childhood to middle age. Psychological Medicine 48 (13), pp.2153-2158. (10.1017/S0033291717003634)
- White, E. K. et al., 2018. Twin classroom dilemma: To study together or separately?. Developmental Psychology 54 (7), pp.1244-1254. (10.1037/dev0000519)
- Martin, J. et al. 2018. Sex-specific manifestation of genetic risk for attention deficit hyperactivity disorder in the general population. Journal of Child Psychology and Psychiatry 59 (8), pp.908-916. (10.1111/jcpp.12874)
2017
- Riglin, L. et al. 2017. Investigating the genetic underpinnings of early-life irritability. Translational Psychiatry 7 e1241. (10.1038/tp.2017.212)
- Riglin, L. et al. 2017. Schizophrenia polygenic risk score and psychotic risk detection - authors' reply. The Lancet Psychiatry 4 (3), pp.188-189. (10.1016/S2215-0366(17)30052-4)
- Riglin, L. et al. 2017. Schizophrenia risk alleles and neurodevelopmental outcomes in childhood: a population-based cohort study. Lancet Psychiatry 4 (1), pp.57-62. (10.1016/S2215-0366(16)30406-0)
- Rice, F. et al. 2017. Adolescent depression and the treatment gap. The Lancet Psychiatry 4 (2), pp.86-87. (10.1016/S2215-0366(17)30004-4)
2016
- Riglin, L. et al. 2016. Association of genetic risk variants with attention-deficit/hyperactivity disorder trajectories in the general population. JAMA Psychiatry 73 (12), pp.1285-1292. (10.1001/jamapsychiatry.2016.2817)
- Neal, S. et al., 2016. Exploring the longitudinal association between interventions to support the transition to secondary school and child anxiety. Journal of Adolescence 50 , pp.31-43. (10.1016/j.adolescence.2016.04.003)
- Ng-Knight, T. et al., 2016. A longitudinal study of self-control at the transition to secondary school: Considering the role of pubertal status and parenting. Journal of Adolescence 50 , pp.44-55. (10.1016/j.adolescence.2016.04.006)
- Riglin, L. et al. 2016. Profiling depression in childhood and adolescence: the role of conduct problems. Journal of Child Psychology and Psychiatry 57 (4), pp.481-490. (10.1111/jcpp.12465)
- Riglin, L. et al. 2016. Higher cognitive ability buffers stress-related depressive symptoms in adolescent girls. Development and Psychopathology 28 (1), pp.97-109. (10.1017/S0954579415000310)
2015
- McManus, I. C. et al., 2015. Doctor, builder, soldier, lawyer, teacher, dancer, shopkeeper, vet: exploratory study of which eleven-year olds would like to become a doctor. BMC Psychology 3 (1) 38. (10.1186/s40359-015-0094-z)
- Rice, F. et al. 2015. Examining reward-seeking, negative self-beliefs and over-general autobiographical memory as mechanisms of change in classroom prevention programs for adolescent depression. Journal of Affective Disorders 186 , pp.320-327. (10.1016/j.jad.2015.07.019)
2014
- Rawal, A. et al., 2014. A longitudinal high-risk study of adolescent anxiety, depression and parent-severity on the developmental course of risk-adjustment. Journal of Child Psychology and Psychiatry 55 (11), pp.1270-1278. (10.1111/jcpp.12279)
- Riglin, L. et al. 2014. The relationship between emotional problems and subsequent school attainment: A meta-analysis. Journal of Adolescence 37 (4), pp.335-346. (10.1016/j.adolescence.2014.02.010)
2013
- Riglin, L. et al. 2013. A longitudinal study of psychological functioning and academic attainment at the transition to secondary school. Journal of Adolescence 36 (3), pp.507-517. (10.1016/j.adolescence.2013.03.002)
Erthyglau
- Fury, B. et al., 2026. Investigating the associations between neurodevelopmental and psychiatric genetic liability and adverse social and functional outcomes across childhood, adolescence and young-adulthood. Molecular Psychiatry (10.1038/s41380-026-03903-x)
- Bekiropoulou, A. et al. 2026. Using a developmental approach to investigate behavioral, neurodevelopmental, and depressive irritability types. JAACAP Open 4 (3), pp.546-562. (10.1016/j.jaacop.2026.02.006)
- Padaigaitė-Gulbinienė, E. et al. 2026. Clinical and cognitive mediators underlying subsequent depression in individuals with attention-deficit/hyperactivity disorder: A developmental approach. Journal of the American Academy of Child & Adolescent Psychiatry (10.1016/j.jaac.2026.06.001)
- Weavers, B. et al. 2026. Heterogeneity in the longitudinal course of depressive symptomatology in adults with a history of recurrent major depressive disorder. Journal of Affective Disorders 403 121498. (10.1016/j.jad.2026.121498)
- Dennison, C. A. et al. 2026. Childhood ADHD and autism spectrum disorder difficulties: exploring the impact of copy number variants on young adult outcomes. BJPsych Open 12 (3) e108. (10.1192/bjo.2026.11018)
- Lewis, K. J. S. et al. 2026. A developmentally informed study of sleep and circadian polygenic scores in adolescence. JAMA Psychiatry 83 (5), pp.523-528. (10.1001/jamapsychiatry.2025.4647)
- Williams, G. et al. 2026. Investigating the symptom presentation of depression in children with ADHD. Journal of Attention Disorders 30 (4), pp.449-459. (10.1177/10870547251366783)
- Dennison, C. A. et al. 2026. The role of rare copy number variants in early‐onset depression. JCPP Advances e70128. (10.1002/jcv2.70128)
- Shakeshaft, A. et al. 2026. Mapping phenotypic and genetic relationships among irritability, depression and ADHD in adolescence using network analysis. Journal of Child Psychology and Psychiatry 67 (3), pp.333-343. jcpp.70040. (10.1111/jcpp.70040)
- Tseng, W. et al., 2026. Cross-Cultural Consortium on Irritability (C3I): An international network for research on cultural similarities and differences in irritability. JAACAP Open 4 (1), pp.184-197. (10.1016/j.jaacop.2025.09.001)
- Bekiropoulou, A. et al. 2026. Measuring irritability across childhood, adolescence, and young adulthood: an investigation of measurement invariance by age, sex, and informant. European Child and Adolescent Psychiatry 35 , pp.121-132. (10.1007/s00787-025-02817-3)
- Dennison, C. A. et al. 2025. Early manifestations of neurodevelopmental copy number variants in children: A population-based investigation. Biological Psychiatry 98 (12), pp.924-933. (10.1016/j.biopsych.2025.03.004)
- Franklin, A. et al., 2025. Cell-type-specific DNA methylation dynamics in the prenatal and postnatal human cortex. Cell Genomics 5 (12) 101010. (10.1016/j.xgen.2025.101010)
- Padaigaitė-Gulbinienė, E. et al. 2025. Study preregistration: clinical and cognitive mediators underlying subsequent depression in individuals with attention-deficit/hyperactivity disorder: a developmental approach. Journal of the American Academy of Child & Adolescent Psychiatry 64 (11), pp.1329-1331. (10.1016/j.jaac.2025.03.023)
- Shakeshaft, A. et al. 2025. Investigating irritability as a potentially causal risk pathway into depression using two genetically informed designs. Biological Society: Global Open Science 5 (6) 100566. (10.1016/j.bpsgos.2025.100566)
- Barrass, L. et al., 2025. Intergenerational educational mobility and mental health: Evidence from a Filipino birth cohort. PLOS Global Public Health 5 (8) e0004570. (10.1371/journal.pgph.0004570)
- Armitage, J. et al. 2025. A cross-country comparison of temporal change in adolescent mental health problems in the UK and Brazil. Epidemiology and Psychiatric Sciences 34 e17. (10.1017/S2045796025000137)
- Riglin, L. et al. 2024. Emotional problems across development: examining measurement invariance across childhood, adolescence and early adulthood. European Child and Adolescent Psychiatry 33 , pp.4237-4245. (10.1007/s00787-024-02461-3)
- Barrass, L. et al., 2024. The association between socioeconomic position and depression or suicidal ideation in low- and middle-income countries in Southeast Asia: a systematic review and meta-analysis. BMC Public Health 24 (1) 3507. (10.1186/s12889-024-20986-9)
- Wootton, R. et al., 2024. Testing maternal effects of vitamin-D and omega-3 levels on offspring neurodevelopmental traits in the Norwegian mother, father and child cohort study. Psychological Medicine 54 (12), pp.3323-3333. (10.1017/S0033291724001466)
- Reed, H. et al., 2024. The unequal impacts of the COVID-19 pandemic on young adults' mental health. Predictors of vulnerability and resilience using longitudinal birth cohort data in the UK. Journal of Adolescence (10.1002/jad.12400)
- Tseliou, F. et al. 2024. Childhood correlates and young adult outcomes of trajectories of emotional problems from childhood to adolescence. Psychological Medicine 54 (10), pp.2504-2514. (10.1017/S0033291724000631)
- Shakeshaft, A. et al. 2024. Estimating the impact of transmitted and non-transmitted psychiatric and neurodevelopmental polygenic scores on youth emotional problems. Molecular Psychiatry 29 , pp.238-246. (10.1038/s41380-023-02319-1)
- Shakeshaft, A. et al. 2024. Long-term physical health conditions and youth anxiety and depression: Is there a causal link?. Psychological Medicine 55 e7. (10.1017/S0033291724003271)
- Agha, S. S. et al., 2024. Young adult ADHD symptoms in the general population and neurocognitive impairment. Journal of Attention Disorders 28 (1), pp.89-98. (10.1177/10870547231201870)
- Dennison, C. et al. 2024. Stratifying early-onset emotional disorders: using genetics to assess persistence in young people of European and South Asian ancestry. Journal of Child Psychology and Psychiatry 65 (1), pp.42-51. (10.1111/jcpp.13862)
- Shakeshaft, A. et al. 2023. Co-development of attention deficit hyperactivity disorder and autistic trait trajectories from childhood to early adulthood. Journal of Child Psychology and Psychiatry 64 (11), pp.1596-1607. (10.1111/jcpp.13851)
- Thapar, A. et al. 2023. Childhood attention deficit hyperactivity disorder problems and mid-life cardiovascular risk: a prospective population cohort study. The British Journal of Psychiatry 223 (4), pp.472-477. (10.1192/bjp.2023.90)
- Weavers, B. et al. 2023. Characterising depression trajectories in young people at high familial risk of depression. Journal of Affective Disorders 337 , pp.66-74. (10.1016/j.jad.2023.05.063)
- Langley, K. et al. 2023. Can a nation-wide e-cohort of ADHD and ASD in childhood be established using Welsh routinely available datasets?. BMJ Open 13 e071851. (10.1136/bmjopen-2023-071851)
- Armitage, J. M. et al. 2023. Validation of the Strengths and Difficulties Questionnaire (SDQ) emotional subscale in assessing depression and anxiety across development. PLoS ONE 18 (7) e0288882. (10.1371/journal.pone.0288882)
- Shakeshaft, A. et al. 2023. Mental-health before and during the COVID-19 pandemic in adults with neurodevelopmental disorders. Journal of Psychiatric Research 159 , pp.230-239. (10.1016/j.jpsychires.2023.01.029)
- Thapar, A. et al. 2023. Practitioner Review: Attention‐deficit hyperactivity disorder and autism spectrum disorder – the importance of depression. Journal of Child Psychology and Psychiatry 64 (1), pp.4-15. (10.1111/jcpp.13678)
- Riglin, L. et al. 2023. Young-adult social outcomes of Attention-Deficit/Hyperactivity Disorder. Journal of Clinical Psychiatry 84 (2) 14379. (10.4088/jcp.22m14379)
- Riglin, L. and Stergiakouli, E. 2022. Mendelian randomisation studies of Attention Deficit Hyperactivity Disorder. JCPP Advances 2 (4) e12117. (10.1002/jcv2.12117)
- Sellers, R. et al. 2022. Using genetic designs to identify likely causal environmental contributions to psychopathology. Development and Psychopathology 34 (5), pp.1653-1665. (10.1017/S0954579422000906)
- Pat, N. et al., 2022. Longitudinally stable, brain-based predictive models mediate the relationships between childhood cognition and socio-demographic, psychological and genetic factors.. Human Brain Mapping 43 (18), pp.5520-5542. (10.1002/hbm.26027)
- Riglin, L. et al. 2022. Early manifestations of genetic liability for ADHD, autism and schizophrenia at ages 18 and 24 months. JCPP Advances 2 (3) e12093. (10.1002/jcv2.12093)
- Tobarra‐Sanchez, E. et al., 2022. Preschool development, temperament and genetic liability as early markers of childhood ADHD: A cohort study. JCPP Advances 2 (3) e12099. (10.1002/jcv2.12099)
- Havdahl, A. et al., 2022. Associations between pregnancy-related predisposing factors for offspring neurodevelopmental conditions and parental genetic liability to Attention-Deficit/Hyperactivity Disorder, Autism, and Schizophrenia: The Norwegian Mother, Father and Child Cohort Study (MoBa). JAMA Psychiatry 79 (8), pp.799-810. (10.1001/jamapsychiatry.2022.1728)
- Riglin, L. et al. 2022. “Late-onset” ADHD symptoms in young adulthood: is this the same as child-onset ADHD?. Journal of Attention Disorders 26 (10), pp.1271-1282. (10.1177/10870547211066486)
- Wootton, R. E. et al., 2022. Decline in attention-deficit hyperactivity disorder traits over the life course in the general population: trajectories across five population birth cohorts spanning ages 3 to 45 years. International Journal of Epidemiology 51 (3), pp.919-930. (10.1093/ije/dyac049)
- Pat, N. et al., 2022. Motivation and cognitive abilities as mediators between polygenic scores and psychopathology in children. Journal of the American Academy of Child and Adolescent Psychiatry 61 (6), pp.782-795. e3. (10.1016/j.jaac.2021.08.019)
- Niina, A. et al., 2022. Exploring ADHD symptoms and associated impairment across development. Journal of Attention Disorders 26 (6), pp.822-830. (10.1177/10870547211025612)
- Riglin, L. et al. 2022. Assessment of age-at-onset criterion for adult attention-deficit hyperactivity disorder. British Journal of Psychiatry 220 (2), pp.73-75. (10.1192/bjp.2021.122)
- Wimberley, T. et al., 2022. Early-life injuries and the development of attention-deficit/hyperactivity disorder. Journal of Clinical Psychiatry 83 (1) 21m14033. (10.4088/JCP.21m14033)
- Dardani, C. et al., 2021. Is genetic liability to ADHD and ASD causally linked to educational attainment?. International Journal of Epidemiology 50 (6), pp.2011-2023. (10.1093/ije/dyab107)
- Eyre, O. et al. 2021. Validation of the short Mood and Feelings Questionnaire in young adulthood. Journal of Affective Disorders 294 , pp.883-888. (10.1016/j.jad.2021.07.090)
- Martin, J. et al. 2021. Sex differences in anxiety and depression in children with ADHD investigating genetic liability and comorbidity. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 186 (7), pp.412-422. (10.1002/ajmg.b.32842)
- Powell, V. et al. 2021. Investigating friendship difficulties in the pathway from ADHD to depressive symptoms. Can parent-child relationships compensate?. Research on Child and Adolescent Psychopathology 49 , pp.1031-1041. (10.1007/s10802-021-00798-w)
- Riglin, L. et al. 2021. ADHD and depression: investigating a causal explanation. Psychological Medicine 51 (11), pp.1890-1897. (10.1017/S0033291720000665)
- Riglin, L. et al. 2021. Variable emergence of Autism Spectrum Disorder symptoms from childhood to early adulthood. American Journal of Psychiatry 178 (8), pp.752-760. (10.1176/appi.ajp.2020.20071119)
- Riglin, L. et al. 2021. Investigating the validity of the strengths and difficulties questionnaire to assess ADHD in young adulthood. Psychiatry Research 301 113984. (10.1016/j.psychres.2021.113984)
- Leppert, B. et al., 2021. The effect of ADHD on physical health outcomes - a two-sample Mendelian randomization study. American Journal of Epidemiology 190 (6), pp.1047-1055. (10.1093/aje/kwaa273)
- Rice, F. et al. 2021. Pupil mental health, concerns and expectations about secondary school as predictors of adjustment across the transition to secondary school: A longitudinal multi-informant study. School Mental Health 13 , pp.279-298. (10.1007/s12310-021-09415-z)
- Riglin, L. et al. 2021. Investigating attention‐deficit hyperactivity disorder and autism spectrum disorder traits in the general population: What happens in adult life?. Journal of Child Psychology and Psychiatry 62 (4), pp.449-457. (10.1111/jcpp.13297)
- Powell, V. et al. 2020. What explains the link between childhood ADHD and adolescent depression? Investigating the role of peer relationships and academic attainment. European Child and Adolescent Psychiatry 29 , pp.1581-1591. (10.1007/s00787-019-01463-w)
- Thapar, A. and Riglin, L. 2020. The importance of a developmental perspective in Psychiatry: what do recent genetic epidemiological findings show?. Molecular Psychiatry 25 , pp.1631-1639. (10.1038/s41380-020-0648-1)
- Riglin, L. et al. 2020. Using genetics to examine a general liability to childhood psychopathology. Behavior Genetics 50 , pp.213-220. (10.1007/s10519-019-09985-4)
- Wimberle, T. et al., 2020. Genetic liability to ADHD and substance use disorders in individuals with ADHD. Addiction 115 (7), pp.1368-1377. (10.1111/add.14910)
- Leppart, B. et al., 2020. A cross-disorder PRS-pheWAS of 5 major psychiatric disorders in UK Biobank. PLoS Genetics 16 (5) e1008185. (10.1371/journal.pgen.1008185)
- Addicoat, A. et al. 2020. Adult mood problems in children with neurodevelopmental problems: evidence from a prospective birth cohort followed to age 50. Social Psychiatry and Psychiatric Epidemiology 55 , pp.351-358. (10.1007/s00127-019-01727-5)
- Ng-Knight, T. et al., 2019. 'Best friends forever'? Friendship stability across school transition and associations with mental health and educational attainment. British Journal of Educational Psychology 89 (4), pp.585-599. (10.1111/bjep.12246)
- Eyre, O. et al. 2019. Irritability in ADHD: association with later depression symptoms. European Child and Adolescent Psychiatry 28 (10), pp.1375-1384. (10.1007/s00787-019-01303-x)
- Riglin, L. et al. 2019. Identifying novel types of irritability using a developmental genetic approach. American Journal of Psychiatry 176 (8), pp.635-642. (10.1176/appi.ajp.2019.18101134)
- Leppert, B. et al., 2019. Association of maternal neurodevelopmental risk alleles with early-life exposures. JAMA Psychiatry 76 (8), pp.834-842. (10.1001/jamapsychiatry.2019.0774)
- Kendall, K. M. et al. 2019. Association of rare copy number variants with risk of depression. JAMA Psychiatry 76 (8), pp.818-825. (10.1001/jamapsychiatry.2019.0566)
- Rice, F. et al. 2019. Characterizing developmental trajectories and the role of neuropsychiatric genetic risk variants in early-onset depression. JAMA Psychiatry 76 (3), pp.306-313. (10.1001/jamapsychiatry.2018.3338)
- Richards, A. et al. 2019. Associations between schizophrenia genetic risk, anxiety disorders and manic/hypomanic episode in a New Zealand longitudinal population cohort study. British Journal of Psychiatry 214 (2), pp.96-102. (10.1192/bjp.2018.227)
- Rice, F. et al. 2019. Adolescent and adult differences in major depression symptom profiles. Journal of Affective Disorders 243 , pp.175-181. (10.1016/j.jad.2018.09.015)
- Riglin, L. et al. 2019. Developmental contributions of schizophrenia risk alleles and childhood peer victimization to early-onset mental health trajectories. American Journal of Psychiatry 176 (1), pp.36-43. (10.1176/appi.ajp.2018.18010075)
- Cooper, M. et al. 2018. Investigating late-onset ADHD: a population cohort investigation. Journal of Child Psychology and Psychiatry 59 (10), pp.1105-1113. (10.1111/jcpp.12911)
- Riglin, L. et al. 2018. The impact of schizophrenia and mood disorder risk alleles on emotional problems: investigating change from childhood to middle age. Psychological Medicine 48 (13), pp.2153-2158. (10.1017/S0033291717003634)
- White, E. K. et al., 2018. Twin classroom dilemma: To study together or separately?. Developmental Psychology 54 (7), pp.1244-1254. (10.1037/dev0000519)
- Martin, J. et al. 2018. Sex-specific manifestation of genetic risk for attention deficit hyperactivity disorder in the general population. Journal of Child Psychology and Psychiatry 59 (8), pp.908-916. (10.1111/jcpp.12874)
- Riglin, L. et al. 2017. Investigating the genetic underpinnings of early-life irritability. Translational Psychiatry 7 e1241. (10.1038/tp.2017.212)
- Riglin, L. et al. 2017. Schizophrenia polygenic risk score and psychotic risk detection - authors' reply. The Lancet Psychiatry 4 (3), pp.188-189. (10.1016/S2215-0366(17)30052-4)
- Riglin, L. et al. 2017. Schizophrenia risk alleles and neurodevelopmental outcomes in childhood: a population-based cohort study. Lancet Psychiatry 4 (1), pp.57-62. (10.1016/S2215-0366(16)30406-0)
- Rice, F. et al. 2017. Adolescent depression and the treatment gap. The Lancet Psychiatry 4 (2), pp.86-87. (10.1016/S2215-0366(17)30004-4)
- Riglin, L. et al. 2016. Association of genetic risk variants with attention-deficit/hyperactivity disorder trajectories in the general population. JAMA Psychiatry 73 (12), pp.1285-1292. (10.1001/jamapsychiatry.2016.2817)
- Neal, S. et al., 2016. Exploring the longitudinal association between interventions to support the transition to secondary school and child anxiety. Journal of Adolescence 50 , pp.31-43. (10.1016/j.adolescence.2016.04.003)
- Ng-Knight, T. et al., 2016. A longitudinal study of self-control at the transition to secondary school: Considering the role of pubertal status and parenting. Journal of Adolescence 50 , pp.44-55. (10.1016/j.adolescence.2016.04.006)
- Riglin, L. et al. 2016. Profiling depression in childhood and adolescence: the role of conduct problems. Journal of Child Psychology and Psychiatry 57 (4), pp.481-490. (10.1111/jcpp.12465)
- Riglin, L. et al. 2016. Higher cognitive ability buffers stress-related depressive symptoms in adolescent girls. Development and Psychopathology 28 (1), pp.97-109. (10.1017/S0954579415000310)
- McManus, I. C. et al., 2015. Doctor, builder, soldier, lawyer, teacher, dancer, shopkeeper, vet: exploratory study of which eleven-year olds would like to become a doctor. BMC Psychology 3 (1) 38. (10.1186/s40359-015-0094-z)
- Rice, F. et al. 2015. Examining reward-seeking, negative self-beliefs and over-general autobiographical memory as mechanisms of change in classroom prevention programs for adolescent depression. Journal of Affective Disorders 186 , pp.320-327. (10.1016/j.jad.2015.07.019)
- Rawal, A. et al., 2014. A longitudinal high-risk study of adolescent anxiety, depression and parent-severity on the developmental course of risk-adjustment. Journal of Child Psychology and Psychiatry 55 (11), pp.1270-1278. (10.1111/jcpp.12279)
- Riglin, L. et al. 2014. The relationship between emotional problems and subsequent school attainment: A meta-analysis. Journal of Adolescence 37 (4), pp.335-346. (10.1016/j.adolescence.2014.02.010)
- Riglin, L. et al. 2013. A longitudinal study of psychological functioning and academic attainment at the transition to secondary school. Journal of Adolescence 36 (3), pp.507-517. (10.1016/j.adolescence.2013.03.002)
Addysgu
Rwy'n goruchwylio prosiectau Cydran a Ddewisir gan Fyfyrwyr meddygol israddedig ac yn goruchwylio prosiectau ymchwil ar gyfer y BSc rhyng-gyfrifedig mewn Seicoleg a Meddygaeth. Rwy'n addysgu dulliau ac ystadegau ymchwil epidemiolegol ar yr MSc Biowybodeg Gymhwysol a Genomeg a rhaglenni MSc Biowybodeg Gymhwysol ac Epidemioleg Genynnol. Rwy'n diwtor personol i fyfyrwyr meddygol israddedig. Rwy'n Gymrawd yr Academi Addysg Uwch (FHEA).
Meysydd goruchwyliaeth
Myfyrwyr presennol
Prif oruchwyliwr ar gyfer Katerina Bekiropoulou (2024 - presennol). Teitl y traethawd hir: A yw anniddigrwydd plentyndod (dysregulation emosiynol) yn nodwedd graidd o ADHD? Cyd-oruchwylwyr: Olga Eyre, Anita Thapar, Jon Heron (Prifysgol Bryste).
Cyd-oruchwyliwr ar gyfer Lucy Barrass (Prifysgol Bryste) (2022 - presennol). Teitl traethawd hir: Dylanwadau cwrs bywyd ar gyfer salwch meddwl: dadansoddiad o ddata carfan o'r Philipinau. Cyd-oruchwylwyr: Duleeka Knipe, Laura Howe, Theresa Redaniel, Nanette Lee (Prifysgol San Carlos, Philippines).
Myfyrwyr blaenorol
Cyd-oruchwyliwr ar gyfer Bryony Weavers (2022 - 2025). Teitl traethawd ymchwil: Plant rhieni iselder: Nodi targedau addawol ar gyfer ymyrraeth. Cyd-oruchwylwyr: Frances Rice, Joanna Martin, Anita Thapar.
