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Dr Victoria Shepherd
(hi/ei)
- Ar gael fel goruchwyliwr ôl-raddedig
Timau a rolau for Victoria Shepherd
Prif Gymrawd Ymchwil
Trosolwyg
Rwy'n Brif Gymrawd Ymchwil ac yn nyrs gofrestredig yn y Ganolfan Ymchwil Treialon lle mae gen i ddiddordeb arbennig mewn gwella cynhwysiant poblogaethau heb eu gwasanaethu gyda ffocws penodol ar boblogaethau a lleoliadau lle gall cydsyniad gwybodus fod yn heriol gan gynnwys defnyddio modelau dirprwy a 'chaniatâd gohiriedig'.
Wedi'i lywio gan fy mhrofiad clinigol blaenorol fel nyrs gofal critigol, rwy'n arwain rhaglen o ymchwil methodolegol sy'n archwilio'r materion moesegol, cyfreithiol ac ymarferol sy'n ymwneud ag ymchwil sy'n cynnwys oedolion sydd heb ganiatâd capasiti a datblygu ymyriadau cymhleth i fynd i'r afael â'r rhwystrau i gynhwysiant. Fel rhan o'r rhaglen ymchwil hon, rwyf wedi datblygu gwefan sy'n darparu gwybodaeth ac adnoddau ar gapasiti a chaniatâd i ymchwil: https://www.capacityconsentresearch.com/
Rwyf hefyd ar yr un pryd yn gweithredu'r gwaith hwn mewn ystod o dreialon clinigol trwy arwain ymchwil fethodolegol fewnosodedig i archwilio a mynd i'r afael â'r rhwystrau a geir mewn poblogaethau a chyd-destunau penodol. Mae fy ngwaith yn cyfrannu at ystod o gydweithrediadau cenedlaethol a rhyngwladol, ac mae'n cael ei ddyfynnu'n eang mewn canllawiau i ymchwilwyr ac yn cael ei amlygu gan sefydliadau sydd â diddordeb mewn gwella cynhwysiant grwpiau sydd heb eu gwasanaethu fel cyllidwyr ymchwil a sefydliadau llywodraethu. O fewn CTR, rwy'n cyd-arwain y Grŵp Cynhwysiant mewn Treialon / Astudiaethau a'r Grŵp Nyrsio, Bydwreigiaeth a Gweithwyr Proffesiynol Iechyd Perthynol (NMAHP). Yn 2025, dyfarnwyd Gwobr Arweinwyr sy'n Dod i'r Amlwg i mi gan Gyfadran Ymchwil Iechyd a Gofal Cymru.
Cyhoeddiad
2025
- Stokes, L. et al. 2025. Barriers and facilitators to implementation of mental capacity legislation in care homes for older adults in the United Kingdom: a mixed-methods systematic review. Age and Ageing 54(5), article number: afaf119. (10.1093/ageing/afaf119)
- Anderson, A. M. et al. 2025. A global call to action for disability inclusion in health research. Nature Medicine (10.1038/s41591-025-03587-w)
- Seeger, R. et al. 2025. Developing a model of advance consent for participation in acute stroke trials. Journal of Stroke 27(1), pp. 133-135. (10.5853/jos.2024.02544)
2024
- Nocivelli, B., Wood, F., Hood, K., Wallace, C. and Shepherd, V. 2024. “Research happens a lot in other settings—so why not here?” A qualitative interview study of stakeholders’ views about advance planning for care home residents’ research participation. Age and Ageing 53(10), article number: afae235. (10.1093/ageing/afae235)
- Udoh, U. et al. 2024. Advance consent for participation in acute stroke trials: a focus group study with people with lived experience of stroke. Canadian Journal of Neurological Sciences (10.1017/cjn.2024.302)
- Biggs, K. et al. 2024. Time to STEP UP: methods and findings from the development of guidance to help researchers design inclusive clinical trials. BMC Medical Research Methodology 24(1), article number: 227. (10.1186/s12874-024-02342-y)
- Udoh, U. et al. 2024. Advance consent for participation in Acute Stroke Trials (ACTION): protocol for a feasibility study. Stroke and Vascular Neurology, article number: 3029. (10.1136/svn-2023-003029)
- Deere, R. et al. 2024. Multi-domain self-management in older people with osteoarthritis and multimorbidities: protocol for the TIPTOE randomised controlled trial. Trials 25, article number: 557. (10.1186/s13063-024-08380-7)
- Shepherd, V., Hood, K. and Wood, F. 2024. ‘It’s not making a decision, it’s prompting the discussions’: a qualitative study exploring stakeholders’ views on the acceptability and feasibility of advance research planning (CONSULT-ADVANCE). BMC Medical Ethics 25(1), article number: 80. (10.1186/s12910-024-01081-5)
- Nocivelli, B., Wood, F., Hood, K., Wallace, C. and Shepherd, V. 2024. Widening research participation: a survey exploring stakeholders' views about opportunities for older adults living in UK care homes to participate in research. Nursing and Residential Care 26(7), pp. 1-9. (10.12968/nrec.2023.0039)
- Griffiths, S., Shepherd, V. and Volkmer, A. 2024. Determining capacity of people with dementia to take part in research: an electronic survey study of researcher confidence, competence and training needs. BMC Medical Ethics 25(1), article number: 65. (10.1186/s12910-024-01056-6)
- Seeger, R. et al. 2024. Advance consent in acute stroke trials: survey of Canadian Research Ethics Board chairs. Canadian Journal of Neurological Sciences 51(2), pp. 285-288. (10.1017/cjn.2023.247)
- Biggs, K. et al. 2024. Effective interventions to increase representation of under-served groups in randomised trials in UK and Ireland: a scoping literature review [version 1; peer review: awaiting peer review]. NIHR Open Research 4, article number: 12. (10.3310/nihropenres.13524.1)
- Shepherd, V. et al. 2024. Improving the inclusion of an under-served group in trials: development and implementation of the INCLUDE Impaired Capacity to Consent Framework. Trials 25(1), article number: 83. (10.1186/s13063-024-07944-x)
2023
- Gillespie, D. et al. 2023. Gut microbiology of UK care home residents: cross-sectional analysis from a randomised controlled trial. Clinical Microbiology and Infection 29(11), pp. 1437-1442. (10.1016/j.cmi.2023.08.001)
- Shepherd, V., Hood, K. and Wood, F. 2023. Planning ahead for research participation: survey of public and professional stakeholders' view about the acceptability and feasibility of advance research planning. BMC Medical Ethics 24, article number: 70. (10.1186/s12910-023-00948-3)
- Nocivelli, B., Shepherd, V., Hood, K., Wallace, C. and Wood, F. 2023. Identifying barriers and facilitators to the inclusion of older adults living in UK care homes in research: a scoping review. BMC Geriatrics 23(1), article number: 446. (10.1186/s12877-023-04126-3)
- Goodwin, V. A. et al. 2023. Including older people in health and social care research: best practice recommendations based on the INCLUDE framework. Age and Ageing 52(6), article number: afad082. (10.1093/ageing/afad082)
- Burgher, T., Shepherd, V. and Nollett, C. 2023. Effective approaches to public involvement in care home research: a systematic review and narrative synthesis. Research Involvement and Engagement 9(38) (10.1186/s40900-023-00453-2)
- Russell, A. M. et al. 2023. Complex and alternate consent pathways in clinical trials: methodological and ethical challenges encountered by underserved groups and a call to action. Trials 24(1), article number: 151. (10.1186/s13063-023-07159-6)
- Udoh, U. et al. 2023. Advance consent in acute stroke trials: survey of canadian stroke physicians. Canadian Journal of Neurological Sciences (10.1017/cjn.2023.12)
- Nocivelli, B., Shepherd, V., Hood, K., Wallace, C. and Wood, F. 2023. Identifying barriers and facilitators to the inclusion of older adults living in UK care homes in research: a scoping review. BMC Geriatrics
2022
- Shepherd, V., Wood, F., Gillies, K., Martin, A., O’Connell, A. and Hood, K. 2022. Feasibility, effectiveness and costs of a decision support intervention for consultees and legal representatives of adults lacking capacity to consent (CONSULT): protocol for a randomised study within a trial. Trials 23(1), article number: 957. (10.1186/s13063-022-06887-5)
- Shepherd, V., Hood, K., Gillies, K. and Wood, F. 2022. Development of a measure to assess the quality of proxy decisions about research participation on behalf of adults lacking capacity to consent: the Combined Scale for Proxy Informed Consent Decisions (CONCORD scale). Trials 23, article number: 843. (10.1186/s13063-022-06787-8)
- Shepherd, V., Wood, F., Gillies, K., O'Connell, A., Martin, A. and Hood, K. 2022. Recruitment interventions for trials involving adults lacking capacity to consent: methodological and ethical considerations for designing Studies Within a Trial (SWATs). Trials 23, article number: 756. (10.1186/s13063-022-06705-y)
- Shepherd, V. et al. 2022. Development of a core outcome set for the evaluation of interventions to prevent COVID-19 in care homes (COS-COVID-PCARE Study). BMC Geriatrics 22, article number: 710. (10.1186/s12877-022-03395-8)
- Dawson, S. et al. 2022. Trial Forge Guidance 3: randomised trials and how to recruit and retain individuals from ethnic minority groups- practical guidance to support better practice. Trials 23, article number: 672.
- Shepherd, V. 2022. (Re)conceptualising 'good' proxy decision-making for research: the implications for proxy consent decision quality. BMC Medical Ethics 23, article number: 75. (10.1186/s12910-022-00809-5)
- Shepherd, V., Hood, K. and Wood, F. 2022. Unpacking the 'black box of horrendousness': a qualitative exploration of the barriers and facilitators to conducting trials involving adults lacking capacity to consent. Trials 23, article number: 471. (10.1186/s13063-022-06422-6)
- Fitzpatrick, A., Wood, F. and Shepherd, V. 2022. Trials using deferred consent in the emergency setting: a systematic review and narrative synthesis of stakeholders' attitudes. Trials 23, article number: 411. (10.1186/s13063-022-06304-x)
2021
- Shepherd, V., Wood, F., Robling, M., Randell, E. and Hood, K. 2021. Development of a core outcome set for the evaluation of interventions to enhance trial participation decisions on behalf of adults who lack capacity to consent: a mixed methods study (COnSiDER Study). Trials 22, article number: 935. (10.1186/s13063-021-05883-5)
- Andreae, M. H., Shah, L. D., Shepherd, V., Sheehan, M., Sacks, H. S. and Rhodes, R. 2021. Decisions on innovation or research for devastating disease. American Journal of Bioethics 21(12), pp. 28-31. (10.1080/15265161.2021.1991042)
- Raven-Gregg, T. and Shepherd, V. 2021. Exploring the inclusion of under-served groups in trials methodology research: an example from ethnic minority populations' views on deferred consent. Trials 22, article number: 589. (10.1186/s13063-021-05568-z)
- Raven-Gregg, T., Wood, F. and Shepherd, V. 2021. Effectiveness of participant recruitment strategies for critical care trials: a systematic review and narrative synthesis. Clinical Trials 18(4), pp. 436-448. (10.1177/1740774520988678)
- Shepherd, V. 2021. Consent support tool: Including people with communication disorders in health research studies [Book Review]. Dementia 20(5), pp. 1855-1856. (10.1177/1471301220985401)
- Butler, C. C. et al. 2021. Probiotics to reduce antibiotic administration in care home residents aged 65 years and older: the PRINCESS RCT. Efficacy and Mechanism Evaluation 8(7) (10.3310/eme08070)
- Shepherd, V. 2021. How nurses can support the inclusion in research of older people who lack capacity to consent. Nursing Older People 33(2), pp. 26-31. (10.7748/nop.2020.e1267)
- Wachhloz, P. A. et al. 2021. Mapping research conducted on long-term care facilities for older people in Brazil: a scoping review. International Journal of Environmental Research and Public Health 18(4), article number: 1522. (10.3390/ijerph18041522)
- Jones, A., Morgan-Jones, P., Busse, M., Shepherd, V. and Wood, F. 2021. Conducting focus groups in neurodegenerative disease populations: ethical and methodological considerations. BMJ Open 11(1), article number: e041869. (10.1136/bmjopen-2020-041869)
- Shepherd, V., Wood, F., Griffith, R., Sheehan, M. and Hood, K. 2021. Development of a decision support intervention for family members of adults who lack capacity to consent to trials. BMC Medical Informatics and Decision Making 21, article number: 30. (10.1186/s12911-021-01390-4)
- Shepherd, V., Griffith, R., Hood, K., Sheehan, M. and Wood, F. 2021. 'There's more to life than money and health': family caregivers' views on the role of Power of Attorney in proxy decisions about research participation for people living with dementia. Dementia 20(1), pp. 308-325. (10.1177/1471301219884426)
2020
- Shepherd, V., Sheehan, M., Hood, K., Griffith, R. and Wood, F. 2020. Constructing authentic decisions: proxy decision making for research involving adults who lack capacity to consent. Journal of Medical Ethics 47(12), article number: e42. (10.1136/medethics-2019-106042)
- Jacinto, A. F. et al. 2020. Using international collaborations to shape research and innovation into care homes in Brazil: a white paper. Journal of Nursing Home Research Sciences 6, pp. 109-113. (10.14283/jnhrs.2020.28)
- Shepherd, V. 2020. Advances and challenges in conducting ethical trials involving populations lacking capacity to consent: a decade in review. Contemporary Clinical Trials 95, article number: 106054. (10.1016/j.cct.2020.106054)
- Kirby, N., Shepherd, V., Howick, J., Betteridge, S. and Hood, K. 2020. Nocebo effects and participant information leaflets: evaluating information provided on adverse effects in UK clinical trials. Trials 21(1), article number: 658. (10.1186/s13063-020-04591-w)
- Butler, C. C. et al. 2020. Effect of probiotic use on antibiotic administration among care home residents: a randomized clinical trial. Journal of the American Medical Association 324(1), pp. 47 - 56. (10.1001/jama.2020.8556)
- Shepherd, V. 2020. Decision-making during pandemics and other serious illness. Geriatrics, Gerontology and Aging 14(2), pp. 79-80. (10.5327/Z2447-21232020142EDT1)
- Shepherd, V. 2020. An under-represented and underserved population in trials: methodological, structural, and systemic barriers to the inclusion of adults lacking capacity to consent. Trials 21(1), article number: 445. (10.1186/s13063-020-04406-y)
- Shepherd, V. and Davies, J. 2020. Conducting a randomized controlled trial in care homes: the challenges of recruiting residents who lack capacity to consent. In: SAGE Research Methods Cases: Medicine and Health. SAGE, (10.4135/9781529726626)
2019
- Wachholz, P. et al. 2019. Research on long-term care homes for older people in Brazil: protocol for a scoping review. East Midlands Research into Ageing Network 32, pp. 1-16.
- Shepherd, V., Hood, K., Sheehan, M., Griffith, R. and Wood, F. 2019. 'It's a tough decision': A qualitative study of proxy decision-making for research involving adults who lack capacity to consent in England and Wales. Age and Ageing 48(6), pp. 903-909. (10.1093/ageing/afz115)
- Shepherd, V. 2019. Deciding about research for others: normative, empirical, and legal accounts of proxy decision-making for research and the development of a decision support intervention. PhD Thesis, Cardiff University.
- Owen-Jones, E. et al. 2019. Protocol for a double-blind placebo-controlled trial to evaluate the efficacy of probiotics in reducing antibiotics for infection in care home residents: the Probiotics to Reduce Infections iN CarE home reSidentS (PRINCESS) trial. BMJ Open 9(6), article number: e027513. (10.1136/bmjopen-2018-027513)
- Shepherd, V., Wood, F., Griffith, R., Sheehan, M. and Hood, K. 2019. Research involving adults lacking capacity to consent: a content analysis of participant information sheets for consultees and legal representatives in England and Wales. Trials 20, article number: 233. (10.1186/s13063-019-3340-5)
- Edvardsson, D. et al. 2019. Advancing long-term care science through using common data elements: candidate measures for care outcomes of personhood, well-being, and quality of life. Gerontology and Geriatric Medicine 5, pp. 1-15. (10.1177/2333721419842672)
- Shepherd, V., Wood, F., Griffith, R., Sheehan, M. and Hood, K. 2019. Protection by exclusion? The (lack of) inclusion of adults who lack capacity to consent to research in clinical trials in the UK. Trials 20, article number: 474. (10.1186/s13063-019-3603-1)
2018
- Shepherd, V., Hood, K., Sheehan, M., Griffith, R., Jordan, A. and Wood, F. 2018. Ethical understandings of proxy decision making for research involving adults lacking capacity: a systematic review (framework synthesis) of empirical research. American Journal of Bioethics 9(4), pp. 267-286. (10.1080/23294515.2018.1513097)
- Francis, N. A. et al. 2018. Oral steroids for hearing loss associated with otitis media with effusion in children aged 2 8 years: the OSTRICH RCT. Health Technology Assessment 22(61) (10.3310/hta22610)
- Jordan, A., Wood, F., Edwards, A., Shepherd, V. and Joseph-Williams, N. 2018. What adolescents living with long-term conditions say about being involved in decision-making about their healthcare: A systematic review and narrative synthesis of preferences and experiences. Patient Education and Counseling 101(10), pp. 1725-1735. (10.1016/j.pec.2018.06.006)
- Shepherd, V., Griffith, R., Sheehan, M., Wood, F. and Hood, K. 2018. Healthcare professionals' understanding of the legislation governing research involving adults lacking mental capacity in England and Wales: a national survey. Journal of Medical Ethics 44(9), pp. 632-637. (10.1136/medethics-2017-104722)
- Francis, N. A. et al. 2018. Oral steroids for resolution of otitis media with effusion in children (OSTRICH): a double-blinded, placebo-controlled randomised trial. Lancet 392(10147), pp. 557-568. (10.1016/S0140-6736(18)31490-9)
2017
- Shepherd, V., Thomas-Jones, E., Ridd, M. J., Hood, K., Addison, K. and Francis, N. 2017. Impact of a deferred recruitment model in a randomised controlled trial in primary care (CREAM study). Trials 18(1), article number: 533. (10.1186/s13063-017-2284-x)
- Francis, N. A. et al. 2017. Oral and topical antibiotics for clinically infected eczema in children: a pragmatic randomized controlled trial in ambulatory care. Annals of Family Medicine 15(2), pp. 124-130. (10.1370/afm.2038)
- Shepherd, V., Wood, F. and Hood, K. 2017. Establishing a set of research priorities in care homes for older people in the UK: a modified Delphi consensus study with care home staff. Age and Ageing 46(2), pp. 284-290. (10.1093/ageing/afw204)
2016
- Gkiousias, V., Butler, C. C., Shepherd, V., Kilgour, J. M., Waldron, C., Thomas-Jones, E. and Francis, N. 2016. Parental perceptions and understanding of information provision, management options and factors influencing the decision-making process in the treatment of children with glue ear. International Journal of Pediatric Otorhinolaryngology 89, pp. 6-12. (10.1016/j.ijporl.2016.07.021)
- Shepherd, V. 2016. Research involving adults lacking capacity to consent: the impact of research regulation on 'evidence biased' medicine. BMC Medical Ethics 17(1), article number: 55. (10.1186/s12910-016-0138-9)
- Francis, N. A. et al. 2016. A randomised placebo-controlled trial of oral and topical antibiotics for children with clinically infected eczema in the community: the ChildRen with Eczema, Antibiotic Management (CREAM) study. Health Technology Assessment 20(19), pp. 1-84. (10.3310/hta20190)
- Waldron, C. et al. 2016. Oral Steroids for the Resolution of Otitis Media with Effusion (OME) in Children (OSTRICH): study protocol for a randomised controlled trial. Trials 17, article number: 115. (10.1186/s13063-016-1236-1)
2015
- Shepherd, V., Nuttall, J., Hood, K. and Butler, C. C. 2015. Setting up a clinical trial in care homes: challenges encountered and recommendations for future research practice. BMC Research Notes 8, article number: 306. (10.1186/s13104-015-1276-8)
2014
- Hood, K. et al. 2014. Probiotics for Antibiotic-Associated Diarrhoea (PAAD): a prospective observational study of antibiotic-associated diarrhoea (including Clostridium difficile-associated diarrhoea) in care homes. Health Technology Assessment 18(63) (10.3310/hta18630)
Articles
- Stokes, L. et al. 2025. Barriers and facilitators to implementation of mental capacity legislation in care homes for older adults in the United Kingdom: a mixed-methods systematic review. Age and Ageing 54(5), article number: afaf119. (10.1093/ageing/afaf119)
- Anderson, A. M. et al. 2025. A global call to action for disability inclusion in health research. Nature Medicine (10.1038/s41591-025-03587-w)
- Seeger, R. et al. 2025. Developing a model of advance consent for participation in acute stroke trials. Journal of Stroke 27(1), pp. 133-135. (10.5853/jos.2024.02544)
- Nocivelli, B., Wood, F., Hood, K., Wallace, C. and Shepherd, V. 2024. “Research happens a lot in other settings—so why not here?” A qualitative interview study of stakeholders’ views about advance planning for care home residents’ research participation. Age and Ageing 53(10), article number: afae235. (10.1093/ageing/afae235)
- Udoh, U. et al. 2024. Advance consent for participation in acute stroke trials: a focus group study with people with lived experience of stroke. Canadian Journal of Neurological Sciences (10.1017/cjn.2024.302)
- Biggs, K. et al. 2024. Time to STEP UP: methods and findings from the development of guidance to help researchers design inclusive clinical trials. BMC Medical Research Methodology 24(1), article number: 227. (10.1186/s12874-024-02342-y)
- Udoh, U. et al. 2024. Advance consent for participation in Acute Stroke Trials (ACTION): protocol for a feasibility study. Stroke and Vascular Neurology, article number: 3029. (10.1136/svn-2023-003029)
- Deere, R. et al. 2024. Multi-domain self-management in older people with osteoarthritis and multimorbidities: protocol for the TIPTOE randomised controlled trial. Trials 25, article number: 557. (10.1186/s13063-024-08380-7)
- Shepherd, V., Hood, K. and Wood, F. 2024. ‘It’s not making a decision, it’s prompting the discussions’: a qualitative study exploring stakeholders’ views on the acceptability and feasibility of advance research planning (CONSULT-ADVANCE). BMC Medical Ethics 25(1), article number: 80. (10.1186/s12910-024-01081-5)
- Nocivelli, B., Wood, F., Hood, K., Wallace, C. and Shepherd, V. 2024. Widening research participation: a survey exploring stakeholders' views about opportunities for older adults living in UK care homes to participate in research. Nursing and Residential Care 26(7), pp. 1-9. (10.12968/nrec.2023.0039)
- Griffiths, S., Shepherd, V. and Volkmer, A. 2024. Determining capacity of people with dementia to take part in research: an electronic survey study of researcher confidence, competence and training needs. BMC Medical Ethics 25(1), article number: 65. (10.1186/s12910-024-01056-6)
- Seeger, R. et al. 2024. Advance consent in acute stroke trials: survey of Canadian Research Ethics Board chairs. Canadian Journal of Neurological Sciences 51(2), pp. 285-288. (10.1017/cjn.2023.247)
- Biggs, K. et al. 2024. Effective interventions to increase representation of under-served groups in randomised trials in UK and Ireland: a scoping literature review [version 1; peer review: awaiting peer review]. NIHR Open Research 4, article number: 12. (10.3310/nihropenres.13524.1)
- Shepherd, V. et al. 2024. Improving the inclusion of an under-served group in trials: development and implementation of the INCLUDE Impaired Capacity to Consent Framework. Trials 25(1), article number: 83. (10.1186/s13063-024-07944-x)
- Gillespie, D. et al. 2023. Gut microbiology of UK care home residents: cross-sectional analysis from a randomised controlled trial. Clinical Microbiology and Infection 29(11), pp. 1437-1442. (10.1016/j.cmi.2023.08.001)
- Shepherd, V., Hood, K. and Wood, F. 2023. Planning ahead for research participation: survey of public and professional stakeholders' view about the acceptability and feasibility of advance research planning. BMC Medical Ethics 24, article number: 70. (10.1186/s12910-023-00948-3)
- Nocivelli, B., Shepherd, V., Hood, K., Wallace, C. and Wood, F. 2023. Identifying barriers and facilitators to the inclusion of older adults living in UK care homes in research: a scoping review. BMC Geriatrics 23(1), article number: 446. (10.1186/s12877-023-04126-3)
- Goodwin, V. A. et al. 2023. Including older people in health and social care research: best practice recommendations based on the INCLUDE framework. Age and Ageing 52(6), article number: afad082. (10.1093/ageing/afad082)
- Burgher, T., Shepherd, V. and Nollett, C. 2023. Effective approaches to public involvement in care home research: a systematic review and narrative synthesis. Research Involvement and Engagement 9(38) (10.1186/s40900-023-00453-2)
- Russell, A. M. et al. 2023. Complex and alternate consent pathways in clinical trials: methodological and ethical challenges encountered by underserved groups and a call to action. Trials 24(1), article number: 151. (10.1186/s13063-023-07159-6)
- Udoh, U. et al. 2023. Advance consent in acute stroke trials: survey of canadian stroke physicians. Canadian Journal of Neurological Sciences (10.1017/cjn.2023.12)
- Nocivelli, B., Shepherd, V., Hood, K., Wallace, C. and Wood, F. 2023. Identifying barriers and facilitators to the inclusion of older adults living in UK care homes in research: a scoping review. BMC Geriatrics
- Shepherd, V., Wood, F., Gillies, K., Martin, A., O’Connell, A. and Hood, K. 2022. Feasibility, effectiveness and costs of a decision support intervention for consultees and legal representatives of adults lacking capacity to consent (CONSULT): protocol for a randomised study within a trial. Trials 23(1), article number: 957. (10.1186/s13063-022-06887-5)
- Shepherd, V., Hood, K., Gillies, K. and Wood, F. 2022. Development of a measure to assess the quality of proxy decisions about research participation on behalf of adults lacking capacity to consent: the Combined Scale for Proxy Informed Consent Decisions (CONCORD scale). Trials 23, article number: 843. (10.1186/s13063-022-06787-8)
- Shepherd, V., Wood, F., Gillies, K., O'Connell, A., Martin, A. and Hood, K. 2022. Recruitment interventions for trials involving adults lacking capacity to consent: methodological and ethical considerations for designing Studies Within a Trial (SWATs). Trials 23, article number: 756. (10.1186/s13063-022-06705-y)
- Shepherd, V. et al. 2022. Development of a core outcome set for the evaluation of interventions to prevent COVID-19 in care homes (COS-COVID-PCARE Study). BMC Geriatrics 22, article number: 710. (10.1186/s12877-022-03395-8)
- Dawson, S. et al. 2022. Trial Forge Guidance 3: randomised trials and how to recruit and retain individuals from ethnic minority groups- practical guidance to support better practice. Trials 23, article number: 672.
- Shepherd, V. 2022. (Re)conceptualising 'good' proxy decision-making for research: the implications for proxy consent decision quality. BMC Medical Ethics 23, article number: 75. (10.1186/s12910-022-00809-5)
- Shepherd, V., Hood, K. and Wood, F. 2022. Unpacking the 'black box of horrendousness': a qualitative exploration of the barriers and facilitators to conducting trials involving adults lacking capacity to consent. Trials 23, article number: 471. (10.1186/s13063-022-06422-6)
- Fitzpatrick, A., Wood, F. and Shepherd, V. 2022. Trials using deferred consent in the emergency setting: a systematic review and narrative synthesis of stakeholders' attitudes. Trials 23, article number: 411. (10.1186/s13063-022-06304-x)
- Shepherd, V., Wood, F., Robling, M., Randell, E. and Hood, K. 2021. Development of a core outcome set for the evaluation of interventions to enhance trial participation decisions on behalf of adults who lack capacity to consent: a mixed methods study (COnSiDER Study). Trials 22, article number: 935. (10.1186/s13063-021-05883-5)
- Andreae, M. H., Shah, L. D., Shepherd, V., Sheehan, M., Sacks, H. S. and Rhodes, R. 2021. Decisions on innovation or research for devastating disease. American Journal of Bioethics 21(12), pp. 28-31. (10.1080/15265161.2021.1991042)
- Raven-Gregg, T. and Shepherd, V. 2021. Exploring the inclusion of under-served groups in trials methodology research: an example from ethnic minority populations' views on deferred consent. Trials 22, article number: 589. (10.1186/s13063-021-05568-z)
- Raven-Gregg, T., Wood, F. and Shepherd, V. 2021. Effectiveness of participant recruitment strategies for critical care trials: a systematic review and narrative synthesis. Clinical Trials 18(4), pp. 436-448. (10.1177/1740774520988678)
- Shepherd, V. 2021. Consent support tool: Including people with communication disorders in health research studies [Book Review]. Dementia 20(5), pp. 1855-1856. (10.1177/1471301220985401)
- Butler, C. C. et al. 2021. Probiotics to reduce antibiotic administration in care home residents aged 65 years and older: the PRINCESS RCT. Efficacy and Mechanism Evaluation 8(7) (10.3310/eme08070)
- Shepherd, V. 2021. How nurses can support the inclusion in research of older people who lack capacity to consent. Nursing Older People 33(2), pp. 26-31. (10.7748/nop.2020.e1267)
- Wachhloz, P. A. et al. 2021. Mapping research conducted on long-term care facilities for older people in Brazil: a scoping review. International Journal of Environmental Research and Public Health 18(4), article number: 1522. (10.3390/ijerph18041522)
- Jones, A., Morgan-Jones, P., Busse, M., Shepherd, V. and Wood, F. 2021. Conducting focus groups in neurodegenerative disease populations: ethical and methodological considerations. BMJ Open 11(1), article number: e041869. (10.1136/bmjopen-2020-041869)
- Shepherd, V., Wood, F., Griffith, R., Sheehan, M. and Hood, K. 2021. Development of a decision support intervention for family members of adults who lack capacity to consent to trials. BMC Medical Informatics and Decision Making 21, article number: 30. (10.1186/s12911-021-01390-4)
- Shepherd, V., Griffith, R., Hood, K., Sheehan, M. and Wood, F. 2021. 'There's more to life than money and health': family caregivers' views on the role of Power of Attorney in proxy decisions about research participation for people living with dementia. Dementia 20(1), pp. 308-325. (10.1177/1471301219884426)
- Shepherd, V., Sheehan, M., Hood, K., Griffith, R. and Wood, F. 2020. Constructing authentic decisions: proxy decision making for research involving adults who lack capacity to consent. Journal of Medical Ethics 47(12), article number: e42. (10.1136/medethics-2019-106042)
- Jacinto, A. F. et al. 2020. Using international collaborations to shape research and innovation into care homes in Brazil: a white paper. Journal of Nursing Home Research Sciences 6, pp. 109-113. (10.14283/jnhrs.2020.28)
- Shepherd, V. 2020. Advances and challenges in conducting ethical trials involving populations lacking capacity to consent: a decade in review. Contemporary Clinical Trials 95, article number: 106054. (10.1016/j.cct.2020.106054)
- Kirby, N., Shepherd, V., Howick, J., Betteridge, S. and Hood, K. 2020. Nocebo effects and participant information leaflets: evaluating information provided on adverse effects in UK clinical trials. Trials 21(1), article number: 658. (10.1186/s13063-020-04591-w)
- Butler, C. C. et al. 2020. Effect of probiotic use on antibiotic administration among care home residents: a randomized clinical trial. Journal of the American Medical Association 324(1), pp. 47 - 56. (10.1001/jama.2020.8556)
- Shepherd, V. 2020. Decision-making during pandemics and other serious illness. Geriatrics, Gerontology and Aging 14(2), pp. 79-80. (10.5327/Z2447-21232020142EDT1)
- Shepherd, V. 2020. An under-represented and underserved population in trials: methodological, structural, and systemic barriers to the inclusion of adults lacking capacity to consent. Trials 21(1), article number: 445. (10.1186/s13063-020-04406-y)
- Wachholz, P. et al. 2019. Research on long-term care homes for older people in Brazil: protocol for a scoping review. East Midlands Research into Ageing Network 32, pp. 1-16.
- Shepherd, V., Hood, K., Sheehan, M., Griffith, R. and Wood, F. 2019. 'It's a tough decision': A qualitative study of proxy decision-making for research involving adults who lack capacity to consent in England and Wales. Age and Ageing 48(6), pp. 903-909. (10.1093/ageing/afz115)
- Owen-Jones, E. et al. 2019. Protocol for a double-blind placebo-controlled trial to evaluate the efficacy of probiotics in reducing antibiotics for infection in care home residents: the Probiotics to Reduce Infections iN CarE home reSidentS (PRINCESS) trial. BMJ Open 9(6), article number: e027513. (10.1136/bmjopen-2018-027513)
- Shepherd, V., Wood, F., Griffith, R., Sheehan, M. and Hood, K. 2019. Research involving adults lacking capacity to consent: a content analysis of participant information sheets for consultees and legal representatives in England and Wales. Trials 20, article number: 233. (10.1186/s13063-019-3340-5)
- Edvardsson, D. et al. 2019. Advancing long-term care science through using common data elements: candidate measures for care outcomes of personhood, well-being, and quality of life. Gerontology and Geriatric Medicine 5, pp. 1-15. (10.1177/2333721419842672)
- Shepherd, V., Wood, F., Griffith, R., Sheehan, M. and Hood, K. 2019. Protection by exclusion? The (lack of) inclusion of adults who lack capacity to consent to research in clinical trials in the UK. Trials 20, article number: 474. (10.1186/s13063-019-3603-1)
- Shepherd, V., Hood, K., Sheehan, M., Griffith, R., Jordan, A. and Wood, F. 2018. Ethical understandings of proxy decision making for research involving adults lacking capacity: a systematic review (framework synthesis) of empirical research. American Journal of Bioethics 9(4), pp. 267-286. (10.1080/23294515.2018.1513097)
- Francis, N. A. et al. 2018. Oral steroids for hearing loss associated with otitis media with effusion in children aged 2 8 years: the OSTRICH RCT. Health Technology Assessment 22(61) (10.3310/hta22610)
- Jordan, A., Wood, F., Edwards, A., Shepherd, V. and Joseph-Williams, N. 2018. What adolescents living with long-term conditions say about being involved in decision-making about their healthcare: A systematic review and narrative synthesis of preferences and experiences. Patient Education and Counseling 101(10), pp. 1725-1735. (10.1016/j.pec.2018.06.006)
- Shepherd, V., Griffith, R., Sheehan, M., Wood, F. and Hood, K. 2018. Healthcare professionals' understanding of the legislation governing research involving adults lacking mental capacity in England and Wales: a national survey. Journal of Medical Ethics 44(9), pp. 632-637. (10.1136/medethics-2017-104722)
- Francis, N. A. et al. 2018. Oral steroids for resolution of otitis media with effusion in children (OSTRICH): a double-blinded, placebo-controlled randomised trial. Lancet 392(10147), pp. 557-568. (10.1016/S0140-6736(18)31490-9)
- Shepherd, V., Thomas-Jones, E., Ridd, M. J., Hood, K., Addison, K. and Francis, N. 2017. Impact of a deferred recruitment model in a randomised controlled trial in primary care (CREAM study). Trials 18(1), article number: 533. (10.1186/s13063-017-2284-x)
- Francis, N. A. et al. 2017. Oral and topical antibiotics for clinically infected eczema in children: a pragmatic randomized controlled trial in ambulatory care. Annals of Family Medicine 15(2), pp. 124-130. (10.1370/afm.2038)
- Shepherd, V., Wood, F. and Hood, K. 2017. Establishing a set of research priorities in care homes for older people in the UK: a modified Delphi consensus study with care home staff. Age and Ageing 46(2), pp. 284-290. (10.1093/ageing/afw204)
- Gkiousias, V., Butler, C. C., Shepherd, V., Kilgour, J. M., Waldron, C., Thomas-Jones, E. and Francis, N. 2016. Parental perceptions and understanding of information provision, management options and factors influencing the decision-making process in the treatment of children with glue ear. International Journal of Pediatric Otorhinolaryngology 89, pp. 6-12. (10.1016/j.ijporl.2016.07.021)
- Shepherd, V. 2016. Research involving adults lacking capacity to consent: the impact of research regulation on 'evidence biased' medicine. BMC Medical Ethics 17(1), article number: 55. (10.1186/s12910-016-0138-9)
- Francis, N. A. et al. 2016. A randomised placebo-controlled trial of oral and topical antibiotics for children with clinically infected eczema in the community: the ChildRen with Eczema, Antibiotic Management (CREAM) study. Health Technology Assessment 20(19), pp. 1-84. (10.3310/hta20190)
- Waldron, C. et al. 2016. Oral Steroids for the Resolution of Otitis Media with Effusion (OME) in Children (OSTRICH): study protocol for a randomised controlled trial. Trials 17, article number: 115. (10.1186/s13063-016-1236-1)
- Shepherd, V., Nuttall, J., Hood, K. and Butler, C. C. 2015. Setting up a clinical trial in care homes: challenges encountered and recommendations for future research practice. BMC Research Notes 8, article number: 306. (10.1186/s13104-015-1276-8)
- Hood, K. et al. 2014. Probiotics for Antibiotic-Associated Diarrhoea (PAAD): a prospective observational study of antibiotic-associated diarrhoea (including Clostridium difficile-associated diarrhoea) in care homes. Health Technology Assessment 18(63) (10.3310/hta18630)
Book sections
- Shepherd, V. and Davies, J. 2020. Conducting a randomized controlled trial in care homes: the challenges of recruiting residents who lack capacity to consent. In: SAGE Research Methods Cases: Medicine and Health. SAGE, (10.4135/9781529726626)
Thesis
- Shepherd, V. 2019. Deciding about research for others: normative, empirical, and legal accounts of proxy decision-making for research and the development of a decision support intervention. PhD Thesis, Cardiff University.
Ymchwil
Trosolwg ymchwil
Mae fy ymchwil yn ceisio gwella cynhwysiant grwpiau heb eu gwasanaethu mewn ymchwil gyda ffocws penodol ar boblogaethau lle gall fod heriau ychwanegol ynghylch cydsyniad gwybodus. Mae fy ngwaith yn canolbwyntio'n bennaf ar archwilio'r heriau moesegol a methodolegol ynghylch cynnwys oedolion sydd heb allu mewn ymchwil a datblygu a gwerthuso ymyriadau i gefnogi cynhwysiant. Rwyf hefyd ar yr un pryd yn gweithredu'r gwaith hwn mewn ystod o dreialon clinigol trwy arwain ymchwil fethodolegol ymgorfforedig i archwilio a mynd i'r afael â'r rhwystrau a geir mewn cyd-destunau penodol. Mae fy ngwaith yn cael ei ddyfynnu'n eang mewn canllawiau i ymchwilwyr a gan sefydliadau fel cyllidwyr ymchwil a sefydliadau llywodraethu.
Oedolion sydd â nam ar y gallu i gydsynio
Ar hyn o bryd mae gennyf Gymrodoriaeth Uwch NIHR a ariennir gan Lywodraeth Cymru drwy Ymchwil Iechyd a Gofal Cymru 'Penderfynu am ymchwil i eraill: astudiaeth ddichonoldeb a threial effeithiolrwydd ymyrraeth cymorth penderfyniadau newydd ar gyfer ymgyngoreion a chynrychiolwyr cyfreithiol oedolion nad ydynt yn gallu cydsynio (CONSULT)' (2021-2026). Bydd yr ymyrraeth (offeryn cymorth penderfyniadau i wella'r broses o wneud penderfyniadau drwy ddirprwy ar gyfer ymchwil yn cael ei werthuso gan ddefnyddio dyluniad 'Astudiaeth o fewn Treial' (SWAT) i ymgorffori'r gwerthusiad mewn hyd at 5 treial lletyol. Gellir dod o hyd i allbynnau CONSULT ar wefan y prosiect (www.capacityconsentresearch.com) ochr yn ochr â gwybodaeth ac adnoddau wedi'u coladu.
Fel rhan o brosiect CONSULT, arweiniais astudiaeth ansoddol sy'n archwilio barn ymchwilwyr a gweithwyr gofal iechyd proffesiynol am y rhwystrau a'r hwyluswyr i gynnal treialon sy'n cynnwys oedolion heb allu cydsynio (Astudiaeth CONSULT-ENABLE). Rwyf hefyd yn arwain yr Astudiaeth CONSULT-ADVANCE i archwilio barn rhanddeiliaid am ddichonoldeb a derbynioldeb cynllunio ymchwil ymlaen llaw, sef proses i bobl fynegi eu dymuniadau am gyfranogiad ymchwil cyn unrhyw golli gallu i gydsynio. Mae'r arolwg a'r astudiaeth cyfweliad ansoddol wedi'u cwblhau a'u cyhoeddi, gyda gwaith pellach wedi'i gynllunio. Rwyf hefyd yn dal Cymrodoriaeth Churchill i archwilio safbwyntiau rhyngwladol ar gynllunio ymlaen llaw ar gyfer ymchwil gydag ymweliadau â Chanada ac Awstralia yn 2024, gan arwain at gyhoeddi fy adroddiad.
Arweiniais y gwaith o ddatblygu set ganlyniadau craidd i werthuso ymyriadau sy'n gwella penderfyniadau dirprwyol ynghylch cyfranogiad ar ran oedolion sydd heb gapasiti (Astudiaeth COnSiDER) sydd wedi'i chofrestru ar gronfa ddata COMET (#1409). Ochr yn ochr â hyn, datblygais fesur canlyniadau newydd i asesu ansawdd y penderfyniadau a wneir am ymchwil ar ran rhywun sydd heb allu i gydsynio - y Combined Scale for Proxy Informed Consent Decisions (graddfa CONCORD).
Arweiniais hefyd y gwaith o ddatblygu Fframwaith Nam ar Gapasiti i Gydsynio NIHR INCLUDE sy'n offeryn i helpu ymchwilwyr i ddylunio treialon sy'n cynnwys oedolion â nam ar y gallu i gydsynio, gyda phecyn cymorth gweithredu a gefnogir gan gyllid 'Arloesi i Bawb' gan Brifysgol Caerdydd (2022-2023). Yn ddiweddar, cwblheais brosiect a ariennir gan Wobr Cyflymydd Effaith UKRI i ddatblygu hyfforddiant CONSULT sy'n seiliedig ar randdeiliaid ar gyfer ymchwilwyr ar ddylunio a chynnal treialon sy'n cynnwys oedolion â nam ar y gallu i gydsynio. Ar hyn o bryd rwy'n arwain prosiect dilynol, a ariennir hefyd gan Wobr Cyflymydd Effaith UKRI, i ddatblygu set o egwyddorion allweddol y dylai ymchwilwyr eu dilyn i sicrhau bod prosesau cydsynio wedi'u cynllunio i fod yn fwy hygyrch mewn treialon (OPTIMISE).
Yn flaenorol, roeddwn yn dal Cymrodoriaeth Ymchwil Doethurol NIHR i archwilio'r heriau moesegol, cyfreithiol ac ymarferol ynghylch cynnwys y poblogaethau hyn sydd wedi'u tangynrychioli, gan ddefnyddio dulliau cymysg a dulliau rhyngddisgyblaethol (2016-2019). Arweiniais astudiaeth ddilynol i gynnal profion gwybyddol o'r ymyrraeth cymorth penderfyniadau (Astudiaeth DECISION 2) a ariennir gan Ymddiriedolaeth Wellcome trwy Cyllid Sefydliadol ISSF (2020).
Rwy'n goruchwylio nifer o fyfyrwyr meddygol BSc rhyngweithiol a phrosiectau PhD yn y maes hwn, ac yn ddiweddar rwyf yn curadu ymchwil ac adnoddau ar 'Ymchwil a gallu i gydsynio' ar gyfer Gofal Cymdeithasol Cymru.
O ddechrau 2026, byddaf yn arwain prosiect 8 mlynedd 'Mynd i'r afael â heriau sy'n seiliedig ar ganiatâd i wella cynhwysiant mewn ymchwil (ACCORD), fel rhan o fy Wobr Datblygu Gyrfa Wellcome.
Treialon Clinigol
Rwy'n arwain prosiect 'Astudiaeth o fewn A' (SWAP) sy'n astudiaeth fethodolegol wedi'i hymgorffori gyda threial i werthuso effeithiolrwydd clinigol a chost ymyrraeth cymorth hunanreoli osteo-arthritis unigol ar y cyd ar gyfer hyrwyddo ansawdd bywyd sy'n gysylltiedig ag iechyd a lleihau costau gofal iechyd (TIPTOE) (2023-2026). Bydd y SWAP wedi'i fewnosod yn archwilio ac yn mynd i'r afael â recriwtio a chadw grwpiau heb eu gwasanaethu yn y treial ac yn nodi rhwystrau i'w cynnwys. Rwyf hefyd yn arwain ail SWAP sy'n archwilio cynnwys grwpiau heb eu gwasanaethu (gan gynnwys pobl hŷn fregus) mewn treial o radiotherapi cynorthwyol mewn cleifion â charcinoma celloedd squamous croenol sylfaenol risg uchel ar ôl llawdriniaeth (SCC-AFTER) (2023-2030), ochr yn ochr ag Ymyrraeth Recriwtio QUINTET (QRI + INCLUSION SWAP).
Fi yw'r arweinydd ar gyfer cynhwysiant mewn treial sy'n gwerthuso gwrthfiotigau ar gyfer canser y croen wlseraidd i leihau'r risg o haint clwyfau ar ôl tynnu llawfeddygol (EXCISE) (2025-2027) a threial sydd ar ddod o gyn-hab ac adsefydlu mewn amnewid ysgwydd (SPRING).
Mae gweithgareddau ymchwil blaenorol yn cynnwys cyfrannu at ddylunio, cyflwyno ac adrodd ar hap treialon rheoledig aml-ganolfan, gan gynnwys: Plant ag Ecsema, Rheoli Gwrthfiotigau - Astudiaeth CREAM (NIHR HTA), STeroids Llafar ar gyfer Datrys cyfryngau otitis gydag effusion (OME) Mewn Plant - Astudiaeth OSTRICH (NIHR HTA) a Probiotics i Lleihau Heintiau iN CarE reSidentS cartref - Astudiaeth PRINCESS (NIHR EME).
Cartrefi Gofal
Mae gen i ddiddordeb arbennig mewn ymchwil cartrefi gofal. Arweiniais Astudiaeth Gosod Blaenoriaethau Ymchwil mewn Cartrefi Gofal ledled y DU, gyda'r nod o nodi set o flaenoriaethau ymchwil ar gyfer ymchwil cartrefi gofal gyda grŵp allweddol o randdeiliaid, a chanlyniad craidd cyfredol ar gyfer atal COVID-19 mewn cartrefi gofal (COS COVID PCARE). Rwyf hefyd yn ymwneud â chydweithio ag ymchwilwyr/sefydliadau cenedlaethol a rhyngwladol eraill i ddatblygu cynigion ymchwil sy'n cynnwys pobl hŷn mewn gofal hirdymor, rhai ohonynt yn mynd i'r afael â meysydd a nodwyd fel blaenoriaethau ymchwil.
Rwy'n gyd-ymgeisydd ar brosiect sy'n datblygu hyfforddiant cymorth hunanreoli ar gyfer gofalwyr oedolion hŷn ag osteoarthritis a chyflyrau ychwanegol (SUSTAIN), a phrosiect i archwilio gweithredu'r Ddeddf Galluedd Meddyliol mewn cartrefi gofal (ENACT).
Ymchwil Methodoleg Treialon
Mae gen i ddiddordeb mewn ymchwil i wella cynnal treialon, gyda ffocws penodol ar wella cynhwysiant poblogaethau heb eu gwasanaethu mewn ymchwil. Rwy'n cyd-arwain y Grŵp Caniatâd Cymhleth ac Amgen o fewn Gweithgor Cynnal Treialon Partneriaeth Ymchwil Methodoleg Treialon MRC-NIHR.
Moeseg Ymchwil
Rwy'n ymwneud â nifer o brosiectau sy'n archwilio agweddau moesegol ar ymchwil, gan gynnwys modelau o ganiatâd a ddefnyddir mewn gwahanol gyd-destunau ymchwil fel y defnydd o gydsyniad uwch mewn sefyllfaoedd brys.
Cyllid a grantiau
2025
- Mynd i'r afael â heriau sy'n seiliedig ar ganiatâd i wella cynhwysiant mewn ymchwil (ACCORD) - Gwobr Datblygu Gyrfa Wellcome (Prif ymgeisydd) (2026-2034)
- Gwobr Arweinwyr sy'n Dod i'r Amlwg, Ymchwil Iechyd a Gofal Cymru (2025-2026)
- Optimeiddio dyluniad prosesau cydsyniad gwybodus ar gyfer ymchwil sy'n cynnwys oedolion â nam ar gyfathrebu a/neu wneud penderfyniadau (OPTIMISE) - Cronfa Cyflymu Effaith UKRI (Prif ymgeisydd) (2025)
2024
- Shoulder Replacement Prehabillitation and Rehabilitating Early (SPRING). Rhaglen Asesu Technoleg Iechyd NIHR (Cyd-ymgeisydd) (2025-2029)
- Cynllunio ymlaen llaw: cyfathrebu dewisiadau am ymchwil trwy gynllunio ymchwil ymlaen llaw. Cymrodoriaeth Churchill (Prif ymgeisydd) (2024)
- Dim llais, dim dewis? Lleihau ffactorau system sy'n ffurfio rhwystr i ymchwil i'r rhai sydd â nam ar allu sy'n agosáu at ddiwedd oes ar draws lleoliadau gofal. GIG Lloegr, Cyllid Rhwydwaith Ymgysylltu â Chymryd Ymchwil (Cyd-ymgeisydd) (2024 – 2025)
- Dichonoldeb Caniatâd ymlaen llaw ar gyfer ParticipaTION mewn Treialon Strôc Acíwt (ACTION). Grant prosiect Sefydliadau Ymchwil Iechyd Canada (Cyd-ymgeisydd) (2024 - 2025)
- EXamining antibiotics for ulCerated skIn cancer Excision Llawfeddygol (EXCISE) Grant prosiect Rhaglen Asesu Technoleg Iechyd NIHR (Cyd-ymgeisydd) (2025-2027)
2023
- Datblygu hyfforddiant sy'n seiliedig ar randdeiliaid ar gyfer ymchwilwyr sy'n dylunio a chynnal treialon sy'n cynnwys oedolion â nam ar y gallu i gydsynio. Cronfa Cyflymu Effaith UKRI (Prif ymgeisydd) (2023 - 2024)
- Hunanreoli parth MulTI mewn Pobl Hŷn gyda OstEoarthritis ac Aml-afiachusrwydd (TIPTOE). Rhaglen Asesu Technoleg Iechyd NIHR (Cyd-ymgeisydd) (2023 - 2026)
- Gwella cyfathrebu â pherthnasau mewn profedigaeth am dreialon brys a gofal critigol (ENHANCE). Ymchwil NIHR er Budd Cleifion (Cyd-ymgeisydd) (2023 - 2024)
- Radiotherapi cynorthwyol mewn cleifion â Carcinoma Celloedd Squamous Croenol cynradd risg uchel AR ôl llawdriniaeth (SCC-AFTER): treial ar hap cam III label agored, aml-ganolfan. Grant prosiect Rhaglen Asesu Technoleg Iechyd NIHR (Cyd-ymgeisydd) (2023 - 2030)
- Dim ymchwil amdanom ni, hebddo! Dileu rhwystrau ymchwil i bobl ag anableddau dysgu. Grant Rhaglen NIHR ar gyfer Grant Datblygu Rhaglenni Ymchwil Gymhwysol (Cyd-ymgeisydd) (2023 – 2024)
- Canolfan Gofal Cymdeithasol i Oedolion (CARE). Dyfarniad seilwaith Ymchwil Iechyd a Gofal Cymru (Cyd-ymgeisydd) (2023 - 2028)
- Gwerthuso hyfforddiant staff a gweithredu'r Ddeddf Galluedd Meddyliol mewn cartrefi gofal i oedolion hŷn (ENACT). Grant prosiect Ymchwil Cyflenwi Iechyd a Gofal Cymdeithasol (HSDR) NIHR (Cyd-ymgeisydd) (2023 – 2026)
- Ymchwil Data Iechyd y DU: Offer ar gyfer Treialon. Dyfarniad seilwaith HDR UK (Cyd-ymgeisydd) (2023 - 2028)
2022
- Implementation o'r 'INCLUDE Imreduced Ability to Consent Framework' ar gyfer ymchwilwyr. Rhaglen Arloesi i Bawb, Prifysgol Caerdydd (Prif ymgeisydd) (2022 - 2023)
- Penderfynu am ymchwil i eraill: astudiaeth ddichonoldeb a threial effeithiolrwydd o ymyrraeth cymorth penderfyniadau newydd ar gyfer ymgyngoreion a chynrychiolwyr cyfreithiol oedolion heb allu cydsynio (CONSULT). Cymrodoriaeth Uwch NIHR (a ariennir gan Ymchwil Iechyd a Gofal Cymru) (Prif ymgeisydd) (2021 - 2026)
- Hyfforddiant cymorth hunanreoli ar gyfer gofalwyr oedolion hŷn ag osteoarthritis a chyflyrau ychwanegol sy'n byw mewn cartrefi gofal (SUSTAIN). Cyngor Ymchwil Economaidd a Chymdeithasol UKRI. Catalydd Heneiddio Iechyd (Cyd-ymgeisydd) (2022 - 2023)
- Ymgysylltu â phreswylwyr cartrefi gofal mewn ymchwil: nodi rhwystrau a hwyluswyr a datblygu ymyrraeth i gefnogi preswylwyr i wneud penderfyniadau a chynllunio ymlaen llaw ar gyfer ymchwil (ENGAGE). Ymchwil Iechyd a Gofal Cymru. Ysgoloriaeth PhD Gofal Cymdeithasol (Cyd-brif ymgeisydd) (2022 - 2024)
2021
- Astudiaeth gydweithredol rhwng CTUs i nodi'r gweithgaredd a'r adnoddau sydd eu hangen i wella cynrychiolaeth grwpiau heb eu gwasanaethu mewn treialon (ACCESS). Cyllid Cymorth CTU NIHR (Cyd-ymgeisydd) (2021 - 2023)
2020
- Gwneud penderfyniadau drwy ddirprwy ar gyfer ymchwil sy'n cynnwys oedolion sydd heb y gallu i gydsynio: profion gwybyddol o ymyrraeth cymorth penderfyniadau newydd a sefydlu set mesur canlyniadau craidd. Gwobr Cydgrynhoi Cronfa Cymorth Strategol Sefydliadol Ymddiriedolaeth Wellcome (Prif ymgeisydd) (2020 - 2020)
- Cydsyniad gwybodus a gwneud penderfyniadau drwy ddirprwy mewn ymchwil sy'n cynnwys oedolion heb allu: datblygu ymyrraeth i gefnogi gwneud penderfyniadau gwybodus ar ddirprwy, wedi'i osod o fewn fframweithiau moesegol a chyfreithiol. Cymrodoriaeth Ymchwil Ddoethurol NIHR (a ariennir gan Ymchwil Iechyd a Gofal Cymru) (Prif ymgeisydd) (2016 - 2019)
Bywgraffiad
Anrhydeddau a dyfarniadau
NHS 75 Faces of Nursing Research (2024)
Cymrodoriaeth Churchill (2023)
Gwobrau Nyrs y Flwyddyn Cymru - Gwobr Cefnogi Gwella Drwy Ymchwil (ail orau, 2019)
PhD Penderfynu ar ymchwil i eraill: cyfrifon normadol, empirig a chyfreithiol o wneud penderfyniadau drwy ddirprwy ar gyfer ymchwil a datblygu ymyrraeth cymorth penderfyniadau (Tachwedd 2019)
BSc Gofal Acíwt a Beirniadol, MA Cyfraith Gofal Iechyd a Moeseg. Traethawd hir: Poblogaethau bregus mewn ymchwil feddygol: a yw rheoleiddio ymchwil yn 'eu diogelu i farwolaeth'? (Medi 2014)
Aelodaethau proffesiynol
NMC (Cyngor Nyrsio a Bydwreigiaeth)
Sefydliad Moeseg Meddygol
Rhwydwaith Cyn-fyfyrwyr Nyrs y Flwyddyn RCN Cymru
Pwyllgorau ac adolygu
Aelod o baneli cyllido cymrodoriaeth - FWO (Gwlad Belg), NIHR, Ymchwil Iechyd a Gofal Cymru
Aelod o Bwyllgor Moeseg Ymchwil y GIG (2019-presennol)
Cadeirydd Grŵp Cynghori ENRICH Cymru (2021-presennol)
Golygydd Ymgynghorol mewn treialon clinigol ac astudiaethau cartrefi gofal ar gyfer Geriatreg, Gerontoleg a Heneiddio (Mawrth 2020-presennol)
adolygydd cyfnodolion (e.e. treialon, oedran a heneiddio, addysg nyrsio mewn ymarfer)
Adolygydd grant (e.e. NIHR, Ymchwil Iechyd a Gofal Cymru, Ymddiriedolaeth Feddygol Dunhill)
Meysydd goruchwyliaeth
Mae gen i ddiddordeb mewn goruchwylio myfyrwyr PhD ym meysydd:
- treialon ymchwil methodoleg sy'n canolbwyntio ar gynnwys grwpiau sydd heb eu gwasanaethu'n ddigonol
- materion moesegol a chyfreithiol mewn ymchwil sy'n cynnwys poblogaethau lle gallai fod heriau o ran galluedd i gydsynio
- Ymchwil cartrefi gofal a chartrefi gofal
- nyrsio gyda ffocws penodol ar ofal critigol a gofal pobl hŷn
Goruchwylio PhD cyfredol:
Teitl: Ymgysylltu â phreswylwyr cartrefi gofal mewn ymchwil: nodi rhwystrau a hwyluswyr a datblygu ymyrraeth i gefnogi preswylwyr i wneud penderfyniadau a chynllunio ymlaen llaw ar gyfer ymchwil (ENGAGE)
Myfyriwr PhD: Llydaw Nocivelli
Tîm goruchwylio: Yr Athro Fiona Wood, Dr Victoria Shepherd, Yr Athro Kerry Hood, Yr Athro Carolyn Wallace
Nod y prosiect PhD dulliau cymysg hwn yw archwilio sut y gall preswylwyr cartrefi gofal a'u gofalwyr ymwneud yn well ag ymchwil, a'r rhwystrau a'r hwyluswyr i'w cynnwys. Gan ddefnyddio dulliau datblygu ymyrraeth sefydledig, bydd ymyrraeth yn cael ei datblygu i gefnogi sgyrsiau am ymchwil gyda phreswylwyr cartrefi gofal a hwyluso cynllunio ymlaen llaw ar gyfer cyfranogiad ymchwil. Bydd y canfyddiadau'n cefnogi cyfleoedd i drigolion cartrefi gofal gymryd rhan mewn ymchwil, sicrhau bod eu lleisiau'n cael eu clywed, a derbyn gofal o ansawdd sy'n seiliedig ar dystiolaeth yn y dyfodol. Fe'i hariennir trwy efrydiaeth PhD Ymchwil Iechyd a Gofal Cymdeithasol Cymru (2021-2024).
Manylion pellach: https://healthandcareresearchwales.org/researchers/our-funded-projects/engaging-care-home-residents-research-identification-barriers-and
Teitl: Ei gwneud hi'n haws i dimau treial ddylunio treialon cynhwysol
Myfyriwr PhD: Azar Alexander-Sefre
Tîm goruchwylio: Yr Athro Shaun Treweek, Dr Heidi Gardner, Dr Victoria Shepherd, Dr Frances Sherratt
Mae angen i gyfranogwyr treial gynrychioli'r rhai mewn cymdeithas y bwriedir iddynt elwa o ganlyniadau'r treial. Bydd y grwpiau sydd angen cynrychiolaeth fwyaf yn amrywio o dreial i dreial. Gall grŵp heb ei wasanaethu ar gyfer un math o dreial fod yn wahanol iawn i grŵp arall. Gall rhesymau dros pam nad yw grwpiau sydd heb eu gwasanaethu yn cael eu cynnwys mewn rhywfaint o ymchwil fod yn gymhleth, ond mae'n haws penderfynu a yw atebion i ddatrys rhwystrau cynhwysiant yn haws i'w penderfynu os cânt eu hystyried o ddechrau treial. Mae croestoriadedd yn mynd gam ymhellach i gydnabod y gallai fod sawl ffactor (er enghraifft ethnigrwydd a rhyw) sy'n cyfuno ac yn arwain at anfantais neu wahaniaethu. Datblygwyd ychydig o offer yn ddiweddar o'r enw Fframweithiau INCLUDE (gweler https://www.trialforge.org/trial-forge-centre/diversity/) i helpu timau treialu i feddwl sut y gallai eu penderfyniadau dylunio ei gwneud hi'n hawdd neu'n anodd i rai grwpiau gymryd rhan. Nod y prosiect PhD dulliau cymysg hwn yw darparu proses symlach i dimau treial lywio eu ffordd trwy'r Fframweithiau'n effeithlon. I wneud hyn, yn gyntaf bydd angen i ni benderfynu ble mae croestoriadoldeb rhwng gwahanol grwpiau sydd heb wasanaeth digonol yn bodoli a beth mae hyn yn ei olygu i ymchwilwyr y bydd angen iddynt ystyried y grwpiau hyn wrth ddylunio eu treialon. Yn ogystal, bydd y prosiect yn ystyried pa fathau o awgrymiadau a all alluogi ymchwilwyr i ymchwilio'n effeithiol i'r rhwystrau a'r heriau y gallai'r poblogaethau croestoriadol hyn eu cael gyda chyfranogiad. Yn olaf, bydd y prosiect yn ymchwilio pa fathau o atebion y gellid eu rhoi i ymchwilwyr i sicrhau bod y cwestiynau Fframwaith hanfodol hyn nid yn unig yn cael eu gofyn ond eu gweithredu, i sicrhau bod eu treialon yn wirioneddol gynhwysol mewn ymarfer. Fe'i hariennir trwy MRC TMRP DTP Ysgoloriaeth ym Mhrifysgol Aberdeen (2022-2025).
Manylion pellach: https://www.abdn.ac.uk/hsru/what-we-do/research/projects/making-it-easier-for-trial-teams-to-design-inclusive-trials-341
Teitl: Gofyn y cwestiynau cywir mewn treialon clinigol canser: Datgloi potensial y fframwaith estimand fel dull amlddisgyblaethol o ddatblygu treialon
Myfyriwr PhD: Morgaine Stiles
Tîm goruchwylio: Yr Athro Christina Yap, Dr Fay Cafferty, Dr Beatriz Goulao, Dr Victoria Shepherd
Manylion pellach: https://mrctmrpdtp.com/2024-entry-dtp-student-profiles/
Goruchwyliwr a enwyd ar Raglen Hyfforddiant Academaidd Clinigol GW4 ar gyfer Gweithwyr Iechyd Proffesiynol (GW4-CAT HP)
Goruchwyliaeth gyfredol
Contact Details
+44 29206 87641
Neuadd Meirionnydd, Ysbyty Athrofaol Cymru, Parc y Mynydd Bychan, Caerdydd, CF14 4YS