![Yasir Ahmed Syed](https://profiles-cardiff.imgix.net/attachments/1231?w=200&h=200&auto=format&crop=faces&fit=crop&q=90")
Dr Yasir Ahmed Syed
Uwch Ddarlithydd
Ysgol y Biowyddorau
- Ar gael fel goruchwyliwr ôl-raddedig
Trosolwyg
Nod cyffredinol fy labordy yw diffinio sail fiolegol anhwylderau niwroddatblygiadol a niwroseiciatrig. Er mwyn cael gwell mewnwelediad i bathogenesis yr anhwylderau datblygiadol ymennydd hyn, megis Anhwylderau Sbectrwm Awtistiaeth (ASD), anhwylderau hwyliau, sgitsoffrenia, ac anhwylderau mater gwyn, rydym yn defnyddio bôn-gelloedd pluripotent sy'n deillio o gleifion ac yn eu gwahaniaethu i mewn i gelloedd linach ac organoidau lluosog niwral in vitro. Rydym yn defnyddio cyfuniad o ddulliau gwyddor selog, genetig, electroffisiolegol, ymddygiadol a materol i ddeall mecanweithiau cychwyn a dilyniant clefydau, ac yn y pen draw datblygu targedau cyffuriau newydd a dibynadwy.
Mae prosiectau cyflenwol yn canolbwyntio ar gyfraniad neuroinflammation a datblygiad mater gwyn wedi'i newid i bathogenesis anhwylderau niwroddatblygiadol a phenoteipiau seiciatrig.
Cyhoeddiad
2024
- Mitchell, M., Spasova, A. and Syed, Y. A. 2024. Unraveling autism: using brain organoids to investigate sex differences in brain development. Biological Psychiatry 4(5), article number: 100360. (10.1016/j.bpsgos.2024.100360)
- Stojanovska, I., Chatterjee, A., Syed, Y. A. and Trajkovski, V. 2024. The utilization of psychopharmacological treatments for individuals with autism spectrum disorder (ASD) in a middle-income European country. Research in Autism Spectrum Disorders 111, article number: 102329. (10.1016/j.rasd.2024.102329)
- Jaddoh, A., Loizides, F., Rana, O. and Syed, Y. A. 2024. Interacting with smart virtual assistants for individuals with dysarthria: a comparative study on usability and user preferences. Applied Sciences 14(4), article number: 1409. (10.3390/app14041409)
2023
- Casella, C. et al. 2023. Differences in white matter detected by ex vivo 9.4T MRI are associated with axonal changes in the R6/1 model of Huntington’s Disease. [Online]. BioRXiv: BioRXiv. (10.1101/2023.10.02.560424) Available at: https://doi.org/10.1101/2023.10.02.560424
- Alam, A. et al. 2023. Modelling the inflammatory response of traumatic brain injury using human induced pluripotent stem cell derived microglia. Journal of Neurotrauma 40(19-20), pp. 2164-2173. (10.1089/neu.2022.0508)
- Nicolaou, K., Carlton, R., Jaddoh, A., Syed, Y., James, J., Abdoulqadir, C. and Loizides, F. 2023. Game based learning rehabilitation for children with speech disabilities: Presenting two bespoke video games. Presented at: BCS HCI: 36th International BCS Human-Computer Interaction Conference, York, UK, 28-29 August 2023.
- Mohammad, F., Shaikh, M. F., Syed, Y. A. and Tissir, F. 2023. Editorial: Advances in understanding synaptic function and its dysfunction in neurological disorders. Frontiers in Molecular Neuroscience 16 (10.3389/fnmol.2023.1239315)
- Koceski, A., Smith, C., Syed, Y. A. and Trajkovski, V. 2023. Understanding the relationship between distress behaviour and health status of people with autism spectrum disorder. Healthcare 11(11), article number: 1565. (10.3390/healthcare11111565)
- Smith, C. J. et al. 2023. Unravelling the clinical co-morbidity and risk factors associated with agenesis of the corpus callosum. Journal of Clinical Medicine 12(11), article number: 3623. (10.3390/jcm12113623)
2022
- Robinson, J. et al. 2022. The association of neurodevelopmental abnormalities, congenital heart and renal defects in a Tuberous Sclerosis Complex patient cohort. BMC Medicine 20, article number: 123. (10.1186/s12916-022-02325-0)
- Dash, S., Syed, Y. A. and Khan, M. R. 2022. Understanding the role of the gut microbiome in brain development and its association with neurodevelopmental psychiatric disorders. Frontiers in Cell and Developmental Biology 10, article number: 880544. (10.3389/fcell.2022.880544)
- Chapman, G. et al. 2022. Using induced pluripotent stem cells to investigate human neuronal phenotypes in 1q21.1 deletion and duplication syndrome. Molecular Psychiatry 27, pp. 819-830. (10.1038/s41380-021-01182-2)
2021
- Dowden, L., Tucker, D., Morgan, S., Uzun, O. and Syed, Y. A. 2021. Contribution of congenital heart disorders associated with copy number variants in mediating risk for brain developmental disorders; evidence from 20-year retrospective cohort study. Frontiers in Cardiovascular Medicine 8, article number: 655463. (10.3389/fcvm.2021.655463)
2020
- Akter, F., Yu, X., Qin, X., Yao, S., Nikrouz, P., Syed, Y. A. and Kotter, M. 2020. Corrigendum: The pathophysiology of degenerative cervical myelopathy and the physiology of recovery following decompression. Frontiers in Neuroscience 14, pp. 628. (10.3389/fnins.2020.00628)
- Drakulic, D. et al. 2020. Copy number variants (CNVs): a powerful tool for iPSC-based modelling of ASD. Molecular Autism 11(1), article number: 42. (10.1186/s13229-020-00343-4)
- Akter, F., Yu, X., Qin, X., Yao, S., Nikrouz, P., Syed, Y. and Kotter, M. 2020. The pathophysiology of degenerative cervical myelopathy and the physiology of recovery following decompression. Frontiers in Neuroscience 14, article number: 138. (10.3389/fnins.2020.00138)
- Savory, K., Manivannan, S., Zaben, M., Uzun, O. and Syed, Y. A. 2020. Impact of copy number variation on human neurocognitive deficits and congenital heart defects: a systematic review. Neuroscience and Biobehavioral Reviews 108, pp. 83-93. (10.1016/j.neubiorev.2019.10.020)
- Savory, K. and Syed, Y. A. 2020. Advances in the understanding of cellular pathogenesis associated with Autism Spectrum Disorder. Journal for ReAttach Therapy and Developmental Diversities 2(2), pp. 96-118.
2019
- Silva, A. I. et al. 2019. Cyfip1 haploinsufficient rats show white matter changes, myelin thinning, abnormal oligodendrocytes and behavioural inflexibility. Nature Communications 10, article number: 3455. (10.1038/s41467-019-11119-7)
2017
- Radtke, F., Chapman, G., Hall, J. and Syed, Y. A. 2017. Modulating neuroinflammation to treat neuropsychiatric disorders. BioMed Research International, article number: 5071786.
2016
- Syed, Y. A., Abdulla, S. A. and Kotter, M. R. N. 2016. Studying the effects of semaphorins on oligodendrocyte lineage cells. In: Terman, J. R. ed. Semaphorin Signaling., Vol. 1493. Methods in Molecular Biology New York, NY: Humana Press, pp. 363-378., (10.1007/978-1-4939-6448-2_26)
- Gonzalez, G. A. et al. 2016. Tamoxifen accelerates the repair of demyelinated lesions in the central nervous system. Scientific Reports 6, article number: 31599. (10.1038/srep31599)
- Dhillon, R. S. et al. 2016. Axonal plasticity underpins the functional recovery following surgical decompression in a rat model of cervical spondylotic myelopathy. Acta Neuropathologica Communications 4, article number: 89. (10.1186/s40478-016-0359-7)
- Syed, Y. A. et al. 2016. Antibody-mediated neutralization of myelin-associated EphrinB3 accelerates CNS remyelination. Acta Neuropathologica 131(2), pp. 281-298. (10.1007/s00401-015-1521-1)
2013
- Syed, Y. A. et al. 2013. Inhibition of phosphodiesterase-4 promotes oligodendrocyte precursor cell differentiation and enhances CNS remyelination. EMBO Molecular Medicine 5(12), pp. 1918-1934. (10.1002/emmm.201303123)
- Hannan, N. et al. 2013. Generation of multipotent foregut stem cells from human pluripotent stem cells. Stem Cell Reports 1(4), pp. 293-306. (10.1016/j.stemcr.2013.09.003)
2011
- Syed, Y. A., Hand, E., Mobius, W., Zhao, C., Hofer, M., Nave, K. A. and Kotter, M. R. 2011. Inhibition of CNS remyelination by the presence of semaphorin 3A. Journal of Neuroscience 31(10), pp. 3719-3728. (10.1523/JNEUROSCI.4930-10.2011)
2009
- Baer, A. S. et al. 2009. Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signalling. Brain 132(2), pp. 465-481. (10.1093/brain/awn334)
2008
- Syed, Y. A., Baer, A. S., Lubec, G., Hoeger, H., Widhalm, G. and Kotter, M. R. 2008. Inhibition of oligodendrocyte precursor cell differentiation by myelin-associated proteins. Neurosurgical Focus 24(3-4), article number: E5. (10.3171/FOC/2008/24/3-4/E4)
Articles
- Mitchell, M., Spasova, A. and Syed, Y. A. 2024. Unraveling autism: using brain organoids to investigate sex differences in brain development. Biological Psychiatry 4(5), article number: 100360. (10.1016/j.bpsgos.2024.100360)
- Stojanovska, I., Chatterjee, A., Syed, Y. A. and Trajkovski, V. 2024. The utilization of psychopharmacological treatments for individuals with autism spectrum disorder (ASD) in a middle-income European country. Research in Autism Spectrum Disorders 111, article number: 102329. (10.1016/j.rasd.2024.102329)
- Jaddoh, A., Loizides, F., Rana, O. and Syed, Y. A. 2024. Interacting with smart virtual assistants for individuals with dysarthria: a comparative study on usability and user preferences. Applied Sciences 14(4), article number: 1409. (10.3390/app14041409)
- Alam, A. et al. 2023. Modelling the inflammatory response of traumatic brain injury using human induced pluripotent stem cell derived microglia. Journal of Neurotrauma 40(19-20), pp. 2164-2173. (10.1089/neu.2022.0508)
- Mohammad, F., Shaikh, M. F., Syed, Y. A. and Tissir, F. 2023. Editorial: Advances in understanding synaptic function and its dysfunction in neurological disorders. Frontiers in Molecular Neuroscience 16 (10.3389/fnmol.2023.1239315)
- Koceski, A., Smith, C., Syed, Y. A. and Trajkovski, V. 2023. Understanding the relationship between distress behaviour and health status of people with autism spectrum disorder. Healthcare 11(11), article number: 1565. (10.3390/healthcare11111565)
- Smith, C. J. et al. 2023. Unravelling the clinical co-morbidity and risk factors associated with agenesis of the corpus callosum. Journal of Clinical Medicine 12(11), article number: 3623. (10.3390/jcm12113623)
- Robinson, J. et al. 2022. The association of neurodevelopmental abnormalities, congenital heart and renal defects in a Tuberous Sclerosis Complex patient cohort. BMC Medicine 20, article number: 123. (10.1186/s12916-022-02325-0)
- Dash, S., Syed, Y. A. and Khan, M. R. 2022. Understanding the role of the gut microbiome in brain development and its association with neurodevelopmental psychiatric disorders. Frontiers in Cell and Developmental Biology 10, article number: 880544. (10.3389/fcell.2022.880544)
- Chapman, G. et al. 2022. Using induced pluripotent stem cells to investigate human neuronal phenotypes in 1q21.1 deletion and duplication syndrome. Molecular Psychiatry 27, pp. 819-830. (10.1038/s41380-021-01182-2)
- Dowden, L., Tucker, D., Morgan, S., Uzun, O. and Syed, Y. A. 2021. Contribution of congenital heart disorders associated with copy number variants in mediating risk for brain developmental disorders; evidence from 20-year retrospective cohort study. Frontiers in Cardiovascular Medicine 8, article number: 655463. (10.3389/fcvm.2021.655463)
- Akter, F., Yu, X., Qin, X., Yao, S., Nikrouz, P., Syed, Y. A. and Kotter, M. 2020. Corrigendum: The pathophysiology of degenerative cervical myelopathy and the physiology of recovery following decompression. Frontiers in Neuroscience 14, pp. 628. (10.3389/fnins.2020.00628)
- Drakulic, D. et al. 2020. Copy number variants (CNVs): a powerful tool for iPSC-based modelling of ASD. Molecular Autism 11(1), article number: 42. (10.1186/s13229-020-00343-4)
- Akter, F., Yu, X., Qin, X., Yao, S., Nikrouz, P., Syed, Y. and Kotter, M. 2020. The pathophysiology of degenerative cervical myelopathy and the physiology of recovery following decompression. Frontiers in Neuroscience 14, article number: 138. (10.3389/fnins.2020.00138)
- Savory, K., Manivannan, S., Zaben, M., Uzun, O. and Syed, Y. A. 2020. Impact of copy number variation on human neurocognitive deficits and congenital heart defects: a systematic review. Neuroscience and Biobehavioral Reviews 108, pp. 83-93. (10.1016/j.neubiorev.2019.10.020)
- Savory, K. and Syed, Y. A. 2020. Advances in the understanding of cellular pathogenesis associated with Autism Spectrum Disorder. Journal for ReAttach Therapy and Developmental Diversities 2(2), pp. 96-118.
- Silva, A. I. et al. 2019. Cyfip1 haploinsufficient rats show white matter changes, myelin thinning, abnormal oligodendrocytes and behavioural inflexibility. Nature Communications 10, article number: 3455. (10.1038/s41467-019-11119-7)
- Radtke, F., Chapman, G., Hall, J. and Syed, Y. A. 2017. Modulating neuroinflammation to treat neuropsychiatric disorders. BioMed Research International, article number: 5071786.
- Gonzalez, G. A. et al. 2016. Tamoxifen accelerates the repair of demyelinated lesions in the central nervous system. Scientific Reports 6, article number: 31599. (10.1038/srep31599)
- Dhillon, R. S. et al. 2016. Axonal plasticity underpins the functional recovery following surgical decompression in a rat model of cervical spondylotic myelopathy. Acta Neuropathologica Communications 4, article number: 89. (10.1186/s40478-016-0359-7)
- Syed, Y. A. et al. 2016. Antibody-mediated neutralization of myelin-associated EphrinB3 accelerates CNS remyelination. Acta Neuropathologica 131(2), pp. 281-298. (10.1007/s00401-015-1521-1)
- Syed, Y. A. et al. 2013. Inhibition of phosphodiesterase-4 promotes oligodendrocyte precursor cell differentiation and enhances CNS remyelination. EMBO Molecular Medicine 5(12), pp. 1918-1934. (10.1002/emmm.201303123)
- Hannan, N. et al. 2013. Generation of multipotent foregut stem cells from human pluripotent stem cells. Stem Cell Reports 1(4), pp. 293-306. (10.1016/j.stemcr.2013.09.003)
- Syed, Y. A., Hand, E., Mobius, W., Zhao, C., Hofer, M., Nave, K. A. and Kotter, M. R. 2011. Inhibition of CNS remyelination by the presence of semaphorin 3A. Journal of Neuroscience 31(10), pp. 3719-3728. (10.1523/JNEUROSCI.4930-10.2011)
- Baer, A. S. et al. 2009. Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signalling. Brain 132(2), pp. 465-481. (10.1093/brain/awn334)
- Syed, Y. A., Baer, A. S., Lubec, G., Hoeger, H., Widhalm, G. and Kotter, M. R. 2008. Inhibition of oligodendrocyte precursor cell differentiation by myelin-associated proteins. Neurosurgical Focus 24(3-4), article number: E5. (10.3171/FOC/2008/24/3-4/E4)
Book sections
- Syed, Y. A., Abdulla, S. A. and Kotter, M. R. N. 2016. Studying the effects of semaphorins on oligodendrocyte lineage cells. In: Terman, J. R. ed. Semaphorin Signaling., Vol. 1493. Methods in Molecular Biology New York, NY: Humana Press, pp. 363-378., (10.1007/978-1-4939-6448-2_26)
Conferences
- Nicolaou, K., Carlton, R., Jaddoh, A., Syed, Y., James, J., Abdoulqadir, C. and Loizides, F. 2023. Game based learning rehabilitation for children with speech disabilities: Presenting two bespoke video games. Presented at: BCS HCI: 36th International BCS Human-Computer Interaction Conference, York, UK, 28-29 August 2023.
Websites
- Casella, C. et al. 2023. Differences in white matter detected by ex vivo 9.4T MRI are associated with axonal changes in the R6/1 model of Huntington’s Disease. [Online]. BioRXiv: BioRXiv. (10.1101/2023.10.02.560424) Available at: https://doi.org/10.1101/2023.10.02.560424
- Syed, Y. A., Abdulla, S. A. and Kotter, M. R. N. 2016. Studying the effects of semaphorins on oligodendrocyte lineage cells. In: Terman, J. R. ed. Semaphorin Signaling., Vol. 1493. Methods in Molecular Biology New York, NY: Humana Press, pp. 363-378., (10.1007/978-1-4939-6448-2_26)
- Gonzalez, G. A. et al. 2016. Tamoxifen accelerates the repair of demyelinated lesions in the central nervous system. Scientific Reports 6, article number: 31599. (10.1038/srep31599)
- Dhillon, R. S. et al. 2016. Axonal plasticity underpins the functional recovery following surgical decompression in a rat model of cervical spondylotic myelopathy. Acta Neuropathologica Communications 4, article number: 89. (10.1186/s40478-016-0359-7)
- Syed, Y. A. et al. 2016. Antibody-mediated neutralization of myelin-associated EphrinB3 accelerates CNS remyelination. Acta Neuropathologica 131(2), pp. 281-298. (10.1007/s00401-015-1521-1)
- Syed, Y. A., Baer, A. S., Lubec, G., Hoeger, H., Widhalm, G. and Kotter, M. R. 2008. Inhibition of oligodendrocyte precursor cell differentiation by myelin-associated proteins. Neurosurgical Focus 24(3-4), article number: E5. (10.3171/FOC/2008/24/3-4/E4)
Ymchwil
Mae anhwylderau niwroddatblygiadol ac anhwylderau seiciatrig yn gyffredin, anhwylderau gwanychol gan gynnwys awtistiaeth, anabledd deallusol, ac efallai hyd yn oed sgitsoffrenia. Gall yr anhwylderau hyn gael effaith ddofn ar wahanol ddimensiynau yr unigolyn, gan gynnwys cymdeithasol ac emosiynol. Mae canfyddiadau genetig diweddar wedi nodi treigladau gan gynnwys newid mewn locws cromosomal o 1q21.1, 3q29 a 16p11.2 sy'n cynyddu'r risg yn sylweddol ar gyfer yr anhwylderau lluosog hyn ar draws rhychwant bywyd. Nid yw'r ffordd y mae'r ffactorau risg hyn yn cyfrannu at ddatblygiad ac ymarferoldeb diffygiol yr ymennydd yn cael ei ddeall yn wael. Mae fy ymchwil wedi canolbwyntio ar nodi sail niwrobiolegol ffactorau risg genetig anhwylderau niwroddatblygiadol a chlefydau seiciatrig gyda'r bwriad o nodi targedau cyffuriau penodol ar gyfer ymyriadau therapiwtig yn y dyfodol o'r anhwylderau ymennydd dinistriol hyn.
Mae ymchwil yn y labordy yn canolbwyntio ar yr amcanion canlynol:
Diffinio sail niwral a moleciwlaidd microcephaly a macrocephaly: Mae microcephaly dynol a macrocephaly yn cyfeirio at gyflyrau niwroddatblygiadol aberrant sy'n gysylltiedig â phennau llai neu fwy o gymharu â babanod o'r un oedran a rhyw. Maen nhw'n bresennol adeg eu geni neu gallant ddatblygu ar ôl eu geni. Mae babanod sy'n gysylltiedig â'r anhwylderau hyn mewn mwy o berygl ar gyfer morbidrwydd hirdymor fel abnormaleddau ymddygiadol, oedi datblygiadol, trawiadau, nam ar y modur a phroblemau gyda golwg a chlyw. Nid yw'r hyn sy'n achosi patrwm rhyfedd twf yr ymennydd dynol yn hysbys eto, gan gyfyngu'r ymdrech i ddatblygu'r triniaethau effeithiol. Mae pynciau sydd â newidiadau dosau genynnau naill ai oherwydd enillion neu ddileu deunydd genetig yng nghromosom dynol 1q21.1 locus yn gysylltiedig yn gryf â chyflwr micro neu macrocephalus. Mae'r locws yn cynnwys sawl genyn allweddol fel HYDIN2, NOTCH2NL sydd wedi'u hawgrymu i reoli maint yr ymennydd ac effeithlonrwydd amlhau y celloedd niwronau. Mae astudio effaith dileu a dyblygu 1q21.1 ar ddatblygiad yr ymennydd yn addo gwasgaru'r patholeg niwral a'r mecanweithiau moleciwlaidd sydd wedi'u rheoleiddio sy'n gysylltiedig â datblygiad ymennydd aberrant. Rydym wedi cynhyrchu bôn-gelloedd pluripotent ysgogol gan unigolion sydd â dileu neu ddyblygu 1q21.1 a'u gwahaniaethu yn "organoidau cortical" neu "ymennydd mini". Gan fod yr organoidau hyn yn dangos pensaernïaeth a gweithgaredd rhwydwaith niwral sy'n debyg i feinwe'r ymennydd dynol, rydym yn eu defnyddio i adnabod diffygion mewn ffurfio cortex, amlhau celloedd niwral a gwahaniaethu.
Mae mecanweithiau mater gwyn yn newid yn yr anhwylder niwroddatblygiadol a salwch meddwl: Adroddwyd yn eang am aflonyddwch microstrwythur mater gwyn yn yr ystod eang o anhwylderau niwroddatblygiadol a chlefydau seiciatrig. Fodd bynnag, mae ymddangosiad y newidiadau hyn a'r mecanwaith cellog sylfaenol yn ystod camau cyn-glinigol a chyfnod cronig y clefyd yn parhau i fod yn brin o ddeall. Gan ddefnyddio amrywiad risg genetig-16p11.2 dileu a dyblygu fel enghreifftiau prototeip, sy'n gysylltiedig â risg uwch ar gyfer awtistiaeth a chyflyrau seiciatrig lluosog, rydym yn defnyddio dulliau bôn-gelloedd blaengar gan gynnwys modelau 2D a 3D o lyelination datblygiadol i ymchwilio i sail moleciwlaidd myelination datblygiadol wedi'i newid. Gall deall y prosesau biolegol penodol hyn a amharir ym mhresenoldeb amrywiolyn risg genetig ddarparu ffenestr foleciwlaidd i brosesau niwroddatblygiadol allweddol sy'n berthnasol i ffenoteipiau niwroseiciatrig.
Cyfraniad niwrolid ar ddatblygiad yr ymennydd: Mae data clinigol ac arbrofol yn darparu tystiolaeth y gall amlygiad amenedigol i ffactorau llidiol newid rhaglenni datblygiad yr ymennydd gan arwain at ffenoteipiau clinigol niwroddatblygiadol a seiciatrig. Mae'n dal yn aneglur a yw presenoldeb ffactorau risg genetig yn cyfrannu at lwybrau llidiol newidiol sy'n arwain at ddatblygiad annormal yr ymennydd. I fynd i'r afael â hyn, rydym yn defnyddio astrocytes a microglia sy'n deillio o iPSC o bynciau sy'n cario amrywiadau genetig risg uchel i nodi unrhyw raglen ddatblygiadol wedi'i newid a'i heffaith ar ymarferoldeb niwronau.
Aelodau'r tîm ymchwil
- Emma Weir
- Kübra Trabzonlu
- Isabelle Harris
Bywgraffiad
Research Fellow/ Group Leader (2017- present), Neuroscience and Mental Health Institute, Cardiff University, Cardiff
Postdoctoral Research Associate (2010 – 2016), Welcome Trust-MRC Cambridge Stem Cell Institute, University of Cambridge, UK
PhD(2005 – 2009) Max-Planck Institute for Experimental Medicine, Germany and Medical University of Vienna, Austria.
Aelodaethau proffesiynol
- Yr Academi Addysg Uwch (FHEA)
- Pwyllgor Ymchwil, Sefydliad Peirianneg a Thrwsio Meinwe Caerdydd (CITER)
- Cymdeithas Geneteg, UK
- International Society for Stem Cell Research.
Pwyllgorau ac adolygu
Aelod bwrdd golygyddol
- Ffiniau mewn Niwrowyddoniaeth
- BMC Neurosceince
- Biomed Reseaarch Rhyngwladol
- Journal for Reattach Therapy and Developmental Diversities.
adolygydd grant
- MRC
- ERC
- Cronfa cyngor Prydain-Newton
- Cymdeithas MS y Deyrnas Unedig.
Meysydd goruchwyliaeth
Mae gen i ddiddordeb mewn goruchwylio myfyrwyr PhD ym meysydd:
- Niwron a Bioleg Cell Glial
- Anhwylderau seiciatrig niwroddatblygiadol
- Neuroinflammation
- Bioargraffu 3D
- Echel ddatblygiadol y galon-ymennydd.
Diddordeb mewn trafod syniadau/ ymuno â'm labordy fel myfyriwr ôl-raddedig/postdoc, cysylltwch â mi drwy e-bost.
Goruchwyliaeth gyfredol
Max Mitchell
Myfyriwr ymchwil
Ymgysylltu
ArrayContact Details
Themâu ymchwil
Arbenigeddau
- Meddygaeth foleciwlaidd
- Aml-forbidrwydd
- Myelination
- Geneteg Seiciatrig
- Niwroddatblygiad