Dr Joanna Zabkiewicz

2026

• Brady, O. P. et al. 2026. Random survival forest versus elastic-net regularized Cox regression for survival prediction in acute myeloid leukemia at distinct treatment time points: model performance comparison study. JMIR Bioinformatics and Biotechnology 7 e75678. (10.2196/75678)
• Phillips, R. et al., 2026. Experimental Cancer Medicine Centre (ECMC) network proposal for a consensus gene panel for pan-cancer sequencing: a Delphi methodology. British Journal of Cancer 134 , pp.289-294. (10.1038/s41416-025-03252-6)

2025

• Dolton, G. et al., 2025. MHC-related protein 1-restricted recognition of cancer via a semi-invariant TCR-α chain.. The Journal of Clinical Investigation 135 (1) e181895. (10.1172/JCI181895)

2024

• Halilovic, M. et al., 2024. Selective degradation of mutant FMS-like tyrosine kinase-3 requires BIM-dependent depletion of heat shock proteins.. Leukemia 38 , pp.2561-2572. (10.1038/s41375-024-02405-5)

2023

• Dolton, G. et al. 2023. Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy. Cell 186 (16), pp.3333-3349. E27. (10.1016/j.cell.2023.06.020)

2020

• Zabkiewicz, J. et al. 2020. Combination of a mitogen‐activated protein kinase inhibitor with the tyrosine kinase inhibitor pacritinib combats cell adhesion‐based residual disease and prevents re‐expansion of FLT3 ‐ITD acute myeloid leukaemia. British Journal of Haematology 191 (2), pp.231-242. (10.1111/bjh.16665)

2016

• Zabkiewicz, J. et al. 2016. The targeted histone deacetylase inhibitor tefinostat (CHR-2845) shows selective in vitro efficacy in monocytoid-lineage leukaemias. Oncotarget 7 (13), pp.16650-16662. (10.18632/oncotarget.7692)

2015

• Lazenby, M. et al. 2015. The HSP90 inhibitor ganetespib: a potential effective agent for Acute Myeloid Leukemia in combination with cytarabine. Leukemia Research 39 (6), pp.617-624. (10.1016/j.leukres.2015.03.016)

2014

• Zabkiewicz, J. et al. 2014. The PDK1 master kinase is over-expressed in acute myeloid leukemia and promotes PKC-mediated survival of leukemic blasts. Haematologica 99 (5), pp.858-864. (10.3324/haematol.2013.096487)

2013

• Hole, P. S. et al. 2013. Overproduction of NOX-derived ROS in AML promotes proliferation and is associated with defective oxidative stress signaling. Blood 122 (19), pp.3322-3330. (10.1182/blood-2013-04-491944)

2011

• Collins, A. M. et al., 2011. Tris(8-hydroxyquinolinato)gallium(III)-loaded copolymer micelles as cytotoxic nanoconstructs for cosolvent-free organometallic drug delivery. Small 7 (12), pp.1635-1640. (10.1002/smll.201100405)

2010

• Zabkiewicz, J. et al. 2010. PDK1 overexpression in acute myeloid leukemia; Clinical significance and potential as a therapeutic target [Abstract]. Blood 116 (21), pp.892-893.

2009

• Shorning, B. et al. 2009. Lkb1 deficiency alters goblet and paneth cell differentiation in the small intestine. PLoS ONE 4 (1) e4264. (10.1371/journal.pone.0004264)

2005

• Zabkiewicz, J. 2005. In vivo modelling of tumour suppressor gene function. PhD Thesis , Cardiff University.

2004

• Zabkiewicz, J. and Clarke, A. R. 2004. DNA damage-induced apoptosis: insights from the mouse. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1705 (1), pp.17-25. (10.1016/j.bbcan.2004.09.002)

2003

• Sansom, O. J. et al. 2003. MBD4 deficiency reduces the apoptotic response to DNA-damaging agents in the murine small intestine. Oncogene 22 (46), pp.7130-7136. (10.1038/sj.onc.1206850)