Professor Paul Kemp
Teams and roles for Paul Kemp
Emeritus Professor
School of Biosciences
Publication
2026
- Brouns, I. et al., 2026. Are pulmonary neuroepithelial bodies sensors for acute airway hypoxia implicated in the central regulation of breathing?. PLoS ONE 21 (6) e0351688. (10.1371/journal.pone.0351688)
2021
- Choompoo, N. et al. 2021. Induced pluripotent stem cells derived from the developing striatum as a potential donor source for cell replacement therapy for Huntington disease. Cytotherapy 23 (2), pp.111-118. (10.1016/j.jcyt.2020.06.001)
2020
- Grimes, L. et al. 2020. Drosophila taste neurons as an agonist-screening platform for P2X receptors. Scientific Reports 10 8292. (10.1038/s41598-020-65169-9)
- Smith-Geater, C. et al., 2020. Aberrant development corrected in adult-onset Huntington's disease iPSC-derived neuronal cultures via WNT signaling modulation. Stem Cell Reports 14 (3), pp.406-419. (10.1016/j.stemcr.2020.01.015)
2019
- Garcia, V. J. et al., 2019. Huntington's disease patient-derived astrocytes display electrophysiological impairments and reduced neuronal support. Frontiers in Neuroscience 13 669. (10.3389/fnins.2019.00669)
2018
- Telezhkin, V. et al. 2018. Kv7 channels are upregulated during striatal neuron development and promote maturation of human iPSC-derived neurons. Pflügers Archiv European Journal of Physiology 470 (9), pp.1359-1376. (10.1007/s00424-018-2155-7)
2017
- Lim, R. G. et al., 2017. Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice. Nature Neuroscience 20 (5), pp.648-660. (10.1038/nn.4532)
2016
- Kemp, P. J. et al. 2016. Improving and accelerating the differentiation and functional maturation of human stem cell-derived neurons: role of extracellular calcium and GABA. The Journal of Physiology 594 (22), pp.6583-6594. (10.1113/JP270655)
- Zhang, G. et al. 2016. The role of Kv1.2 channel in electrotaxis cell migration. Journal of Cellular Physiology 231 (6), pp.1375-1384. (10.1002/jcp.25259)
- Young, F. I. et al. 2016. Clonal heterogeneity in the neuronal and glial differentiation of dental pulp stem/progenitor cells. Stem Cells International 2016 1290561. (10.1155/2016/1290561)
- Telezhkin, V. et al., 2016. Forced cell-cycle exit and modulation of GABAA, CREB and GSK3β signaling promote functional maturation of induced pluripotent stem cell-derived neurons. American Journal of Physiology - Cell Physiology ajpcell.00166.2015. (10.1152/ajpcell.00166.2015)
- Yarova, P. L. et al. 2016. Inhaled calcilytics: effects on airway inflammation and remodeling. Respiratory Drug Delivery 1 , pp.1-12.
- Brennan, S. C. et al. 2016. The extracellular calcium-sensing receptor regulates human fetal lung development via CFTR. Scientific Reports 6 21975. (10.1038/srep21975)
- Schepelmann, M. et al. 2016. The vascular Ca2+-sensing receptor regulates blood vessel tone and blood pressure. American Journal of Physiology - Cell Physiology 310 (3), pp.C193-C204. (10.1152/ajpcell.00248.2015)
- Stephen P., B. , Telezhkin, V. and Kemp, P. 2016. Functional interactions between BKCa a-subunit and Annexin A5: implications in apoptosis. Oxidative Medicine and Cellular Longevity 2016 1607092. (10.1155/2016/1607092)
2015
- Straccia, M. et al., 2015. Quantitative high-throughput gene expression profiling of human striatal development to screen stem cell-derived medium spiny neurons. Molecular Therapy - Methods & Clinical Development 2 15030. (10.1038/mtm.2015.30)
- Hänggi, P. et al., 2015. Functional plasticity of the N-methyl-d-aspartate receptor in differentiating human erythroid precursor cells. American Journal of Physiology - Cell Physiology 308 (12), pp.C993-C1007. (10.1152/ajpcell.00395.2014)
- Yarova, P. L. et al. 2015. Calcium-sensing receptor antagonists abrogate airways hyperresponsiveness and inflammation in allergic asthma. Science Translational Medicine 7 (284) 284ra60. (10.1126/scitranslmed.aaa0282)
2014
- Kemp, P. J. and Telezhkin, V. 2014. Oxygen sensing by the carotid body: is it all just rotten eggs?. Antioxidants & Redox Signaling 20 (5), pp.794-804. (10.1089/ars.2013.5377)
2013
- Lembrechts, R. et al., 2013. Functional expression of the multimodal extracellular calcium-sensing receptor in pulmonary neuroendocrine cells. Journal of Cell Science 126 (19), pp.4490-4501. (10.1242/jcs.131656)
- Matsa, E. et al., 2013. Allele-specific RNA interference rescues the long-QT syndrome phenotype in human-induced pluripotency stem cell cardiomyocytes. European Heart Journal 35 (16), pp.1078-1087. (10.1093/eurheartj/eht067)
- Brennan, S. C. et al. 2013. Fetal calcium regulates branching morphogenesis in the developing human and mouse lung: involvement of voltage-gated calcium channels. PLoS ONE 8 (11), pp.e80294. (10.1371/journal.pone.0080294)
- Rushton, D. J. et al. 2013. Stimulation of GABA-induced Ca2+ influx enhances maturation of human induced pluripotent stem cell-derived neurons. PLoS ONE 8 (11), pp.e81031. (10.1371/journal.pone.0081031)
- Shore, A. et al. 2013. A Comparative approach to understanding tissue-specific expression of uncoupling protein 1 expression in adipose tissue. Frontiers in Genetics 3 304. (10.3389/fgene.2012.00304)
- Shore, A. et al. 2013. Cold-induced changes in gene expression in brown adipose tissue, white adipose tissue and liver. PLoS ONE 8 (7) e68933. (10.1371/journal.pone.0068933)
2012
- Mattis, V. B. et al., 2012. Induced pluripotent stem cells from patients with Huntington's Disease show CAG-repeat-expansion-associated phenotypes. Cell Stem Cell 11 (2), pp.264-278. (10.1016/j.stem.2012.04.027)
- Riccardi, D. and Kemp, P. J. 2012. The calcium-sensing receptor beyond extracellular calcium homeostasis: Conception, development, adult physiology, and disease. Annual Review of Physiology 74 , pp.271-297. (10.1146/annurev-physiol-020911-153318)
- Wray, S. et al., 2012. Creation of an open-access, mutation-defined fibroblast resource for neurological disease research. PLoS ONE 7 (8) e43099. (10.1371/journal.pone.0043099)
2011
- Cayzac, S. H. et al., 2011. Spermine attenuates carotid body glomus cell oxygen sensing by inhibiting L-type Ca2+ channels. Respiratory Physiology & Neurobiology 175 (1), pp.80-89. (10.1016/j.resp.2010.09.009)
- Finney, B. et al. 2011. An exon 5-less splice variant of the extracellular calcium-sensing receptor rescues absence of the full-length receptor in the developing mouse lung. Experimental Lung Research 37 (5), pp.269-278. (10.3109/01902148.2010.545471)
- Kelly, C. et al. 2011. Medical terminations of pregnancy: A viable source of tissue for cell replacement therapy for neurodegenerative disorders. Cell Transplantation 20 (4), pp.503-513. (10.3727/096368910X546580)
- Telezhkin, V. et al., 2011. Cysteine residue 911 in C-terminal tail of human BKCaα channel subunit is crucial for its activation by carbon monoxide. Pflugers Archiv-European Journal of Physiology 461 (6), pp.665-675. (10.1007/s00424-011-0924-7)
- Wilkinson, W. J. et al. 2011. Alveolar epithelial CNGA1 channels mediate cGMP-stimulated, amiloride-insensitive, lung liquid absorption. Pflügers Archiv European Journal of Physiology 462 (2), pp.267-279. (10.1007/s00424-011-0971-0)
- Wilkinson, W. J. and Kemp, P. J. 2011. Carbon monoxide: an emerging regulator of ion channels. The Journal of Physiology 589 (13), pp.3055-3062. (10.1113/jphysiol.2011.206706)
- Wilkinson, W. J. and Kemp, P. J. 2011. The carbon monoxide donor, CORM-2, is an antagonist of ATP-gated, human P2X4 receptors. Purinergic Signalling 7 (1), pp.57-64. (10.1007/s11302-010-9213-8)
2010
- Shore, A. et al. 2010. Role of Ucp1 enhancer methylation and chromatin remodelling in the control of Ucp1 expression in murine adipose tissue. Diabetologia 53 (6), pp.1164-1173. (10.1007/s00125-010-1701-4)
- Telezhkin, V. et al., 2010. Mechanism of inhibition by hydrogen sulfide of native and recombinant BKCa channels. Respiratory Physiology & Neurobiology 172 (3), pp.169-178. (10.1016/j.resp.2010.05.016)
- Warburton, D. et al., 2010. Lung organogenesis. Current Topics in Developmental Biology 90 , pp.73-158. (10.1016/S0070-2153(10)90003-3)
2009
- Brazier, S. P. et al. 2009. Cysteine residues in the C-terminal tail of the human BKCaα subunit are important for channel sensitivity to carbon monoxide. Presented at: International Society of Arterial Chemoreception. 17th Meeting Valladolid, Spain 1-5 July 2008. Arterial Chemoreceptors. Advances in Experimental Medicine and Biology Vol. 648. Netherlands: Springer Netherlands. , pp.49-56. (10.1007/978-90-481-2259-2_5)
- Cayzac, S. et al., 2009. Effects of the polyamine spermine on arterial chemoreception. Presented at: International Society of Arterial Chemoreception. 17th Meeting Valladolid, Spain 1-5 July 2008. Published in: Gonzalez, C. , Nurse, C. A. and Peers, C. eds. Arterial chemoreceptors. Advances in Experimental Medicine and Biology Vol. 648. Netherlands: Springer Netherlands. , pp.97-104. (10.1007/978-90-481-2259-2_11)
- De Proost, I. et al., 2009. Purinergic signaling in the pulmonary neuroepithelial body microenvironment unraveled by live cell imaging. The FASEB Journal 23 (4), pp.1153-1160. (10.1096/fj.08-109579)
- Kemp, P. J. and Peers, C. 2009. Enzyme-linked acute oxygen sensing in airway and arterial chemoreceptors. In: Gonzalez, C. , Nurse, C. A. and Peers, C. eds. Arterial Chemoreceptors. Advances in Experimental Medicine and Biology Vol. 648.Netherlands: Springer Netherlands. , pp.39-48. (10.1007/978-90-481-2259-2_4)
- Kemp, P. J. et al. 2009. Enzyme-linked oxygen sensing by potassium channels. Annals of the New York Academy of Sciences 1177 , pp.112-118. (10.1111/j.1749-6632.2009.05025.x)
- Riccardi, D. et al. 2009. Novel regulatory aspects of the extracellular Ca2+-sensing receptor, CaR. Pflugers Archiv-European Journal of Physiology 458 (6), pp.1007-1022. (10.1007/s00424-009-0681-z)
- Telezhin, V. et al., 2009. Hydrogen Sulfide inhibits human BKCa channels. Advances in Experimental Medicine and Biology 648 , pp.65-72. (10.1007/978-90-481-2259-2_7)
- Wilkinson, W. J. et al. 2009. Carbon monoxide is a rapid modulator of recombinant and native P2X(2) ligand-gated ion channels. British Journal of Pharmacology 158 (3), pp.862-871. (10.1111/j.1476-5381.2009.00354.x)
2008
- De Proost, I. et al., 2008. Functional live cell imaging of the pulmonary neuroepithelial body microenvironment. American Journal of Respiratory Cell and Molecular Biology 39 (2), pp.180-189. (10.1165/rcmb.2008-0011OC)
- Finney, B. et al. 2008. Regulation of mouse lung development by the extracellular calcium-sensing receptor, CaR. Journal of Physiology 586 (24), pp.6007-6019. (10.1113/jphysiol.2008.161687)
- Timmermans, J. P. et al., 2008. Expression of P2X receptors in LAD-2 cells and human lung mast cells [Abstract]. Purinergic Signalling 4 (S1), pp.S159. (10.1007/s11302-008-9116-0)
- Wilkinson, W. J. et al. 2008. Carbon monoxide is a rapid modulator of recombinant and native P2X2 ligand-gated ion channels [Abstract]. Purinergic Signalling 4 (S1), pp.26. (10.1007/s11302-008-9116-0)
- Williams, S. E. et al., 2008. A structural motif in the C-terminal tail of slo1 confers carbon monoxide sensitivity to human BKCa channels. Pflugers Archiv-European Journal of Physiology 456 (3), pp.561-572. (10.1007/s00424-007-0439-4)
2007
- Dvorak, M. M. et al., 2007. Thiazide Diuretics Directly Induce Osteoblast Differentiation and Mineralized Nodule Formation by Interacting with a Sodium Chloride Co-Transporter in Bone. Journal of the American Society of Nephrology 18 (9), pp.2509-2516. (10.1681/ASN.2007030348)
- Kemp, P. J. and Peers, C. 2007. Oxygen sensing by ion channels. Essays in Biochemistry 43 , pp.77-90. (10.1042/bse0430077)
- Joannides, A. J. et al., 2007. Environmental signals regulate lineage choice and temporal maturation of neural stem cells from human embryonic stem cells. Brain 130 (5), pp.1263-1275. (10.1093/brain/awm070)
2006
- Buckler, K. J. et al., 2006. Discussion. Novartis Foundation Symposium 272 , pp.228-233.
- Chandel, N. S. et al., 2006. Discussion. Novartis Foundation Symposium 272 , pp.151-156.
- Duchen, M. et al., 2006. Discussion. Novartis Foundation Symposium 272 , pp.100-105.
- Joannides, A. J. et al., 2006. A scaleable and defined system for generating neural stem cells from human embryonic stem cells. Stem Cells 25 (3), pp.731-737. (10.1634/stemcells.2006-0562)
- Kemp, P. J. 2006. Detecting acute changes in oxygen: will the real sensor please stand up?. Experimental Physiology 91 (5), pp.829-834. (10.1113/expphysiol.2006.034587)
- Kemp, P. J. et al. 2006. General discussion III. Novartis Foundation Symposium 272 , pp.214-217.
- Kemp, P. J. et al. 2006. In search of the acute oxygen sensor: Functional proteomics and acute regulation of large-conductance, calcium-activated potassium channels by hemeoxygenase-2. In: Hayashida, Y. , Gonzalez, C. and Kondo, H. eds. The Arterial Chemoreceptors. Vol. 580, Advances in Experimental Medicine and Biology Springer. , pp.137-146. (10.1007/0-387-31311-7_21)
- Kemp, P. J. et al. 2006. Functional proteomics of BK potassium channels: Defining the acute oxygen sensor. In: Chadwick, D. J. and Goode, J. eds. Signalling Pathways in Acute Oxygen Sensing: Novartis Foundation Symposium 272. Novartis Foundation Symposia Wiley-Blackwell. , pp.141-151. (10.1002/9780470035009.ch12)
- Kemp, P. J. et al. 2006. General discussion II. Novartis Foundation Symposium (272), pp.131-140.
- Kummer, W. et al., 2006. Discussion. Novartis Foundation Symposium 272 , pp.114-118.
- Peers, C. et al., 2006. General discussion I. Novartis Foundation Symposium (272), pp.33-36.
- Peers, C. et al., 2006. Hypoxic regulation of Ca2+ signalling in astrocytes and endothelial cells. In: Chadwick, D. and Goode, J. eds. Signalling Pathways in Acute Oxygen Sensing: Novartis Foundation Symposium 272. Wiley-Blackwell. , pp.119-127. (10.1002/9780470035009.ch10)
- Peers, C. et al., 2006. Hypoxic regulation of Ca2+ signalling in astrocytes and endothelial cells. In: Hayashida, Y. , Gonzalez, C. and Konda, H. eds. The Arterial Chemoreceptors. Vol. 580, Advances in Experimental Medicine and Biology Kluwer. , pp.185-190. (10.1007/0-387-31311-7_28)
2005
- Aley, P. K. et al., 2005. Hypoxic modulation of Ca2+ signaling in human venous endothelial cells: MULTIPLE ROLES FOR REACTIVE OXYGEN SPECIES. Journal of Biological Chemistry 280 (14), pp.13349-13354. (10.1074/jbc.M413674200)
- Bourke, S. et al., 2005. Development of a lung slice preparation for recording ion channel activity in alveolar epithelial type I cells. Respiratory Research 6 40. (10.1186/1465-9921-6-40)
- Brazier, S. P. et al., 2005. Cloning of the human TASK-2 (KCNK5) promoter and its regulation by chronic hypoxia. Biochemical and Biophysical Research Communications 336 (4), pp.1251-1258. (10.1016/j.bbrc.2005.09.007)
- Kemp, P. J. 2005. Hemeoxygenase-2 as an O2 sensor in K+ channel-dependent chemotransduction. Biochemical and Biophysical Research Communications 338 (1), pp.648-652. (10.1016/j.bbrc.2005.08.110)
- Miller, P. , Kemp, P. J. and Peers, C. 2005. Structural requirements for O2 sensing by the human tandem-P domain channel, hTREK1. Biochemical and Biophysical Research Communications 331 (4), pp.1253-1256. (10.1016/j.bbrc.2005.04.042)
2004
- Williams, S. E. J. et al., 2004. Hemoxygenase-2 is an oxygen sensor for a calcium-sensitive potassium channel. Science , pp.2993-2997. (10.1126/science.1105010)
- Miller, P. , Peers, C. and Kemp, P. J. 2004. Polymodal regulation of hTREK1 by pH, arachidonic acid, and hypoxia: Physiological impact in acidosis and alkalosis. American Journal of Physiology - Cell Physiology 286 (2), pp.C272-C282. (10.1152/ajpcell.00334.2003)
- Hammond, L. C. et al., 2004. Chronic hypoxia up-regulates expression of adenosine A1 receptors in DDT1-MF2 cells. Biochemical Pharmacology 67 (3), pp.421-426. (10.1016/j.bcp.2003.09.003)
- Kemp, P. J. , Iles, D. and Peers, C. 2004. Oxygen sensing by human recombinant K+ channels: assessment of the use of stable cell lines. Methods in Enzymology 381 , pp.257-274. (10.1016/S0076-6879(04)81018-8)
- Kemp, P. J. and Kim, K. 2004. Spectrum of ion channels in alveolar epithelial cells: implications for alveolar fluid balance. AJP: Lung Cellular and Molecular Physiology 287 (3), pp.L460-L464. (10.1152/ajplung.00191.2004)
- Kemp, P. J. and Peers, C. 2004. Assessment of oxygen sensing by model airway and arterial chemoreceptors. Methods in Enzymology 381 , pp.3-25. (10.1016/S0076-6879(04)81001-2)
- Kemp, P. J. et al. 2004. Regulation of recombinant human brain tandem P domain K+ channels by hypoxia: A role for O2 in the control of neuronal excitability?. Journal of Cellular and Molecular Medicine 8 (1), pp.38-44. (10.1111/j.1582-4934.2004.tb00258.x)
- Mason, H. S. , Bourke, S. and Kemp, P. J. 2004. Selective modulation of ligand-gated P2X purinoceptor channels by acute hypoxia is mediated by reactive oxygen species. Molecular Pharmacology 66 (6), pp.1525-1535. (10.1124/mol.104.000851)
- Peers, C. and Kemp, P. J. 2004. Ion channel regulation by chronic hypoxia in models of acute oxygen sensing. Cell Calcium 36 (3-4), pp.341-348. (10.1016/j.ceca.2004.02.005)
- Williams, S. E. et al., 2004. siRNA knock-down of γ-glutamyl transpeptidase does not affect hypoxic K+ channel inhibition. Biochemical and Biophysical Research Communications 314 (1), pp.63-68. (10.1016/j.bbrc.2003.12.052)
2003
- Hartness, M. E. et al., 2003. Post-transcriptional control of human maxiK potassium channel activity and acute oxygen sensitivity by chronic hypoxia. Journal of Biological Chemistry , pp.51422-51432. (10.1074/jbc.M309463200)
- Kemp, P. J. , Peers, C. and Lewis, A. 2003. Oxygen sensing by human recombinant large conductance, calcium-activated potassium channels. Regulation by acute hypoxia. Advances in Experimental Medicine and Biology 536 , pp.209-215.
- Kemp, P. J. et al. 2003. Acute oxygen sensing in cellular models: relevance to the physiology of pulmonary neuroepithelial and carotid bodies. Anatomical Record - Part A Discoveries in Molecular, Cellular, and Evolutionary Biology 270A (1), pp.41-50. (10.1002/ar.a.10008)
- Miller, P. et al., 2003. Acute hypoxia occludes hTREK-1 modulation: re-evaluation of the potential role of tandem P domain K+ channels in central neuroprotection. The Journal of Physiology 548 (1), pp.31-37. (10.1113/jphysiol.2003.040048)
2002
- Lewis, A. et al., 2002. Hypoxia inhibits human recombinant large conductance, Ca2+-activated K+ (maxi-K) channels by a mechanism which is membrane delimited and Ca2+ sensitive. The Journal of Physiology 540 (3), pp.771-780. (10.1113/jphysiol.2001.013888)
- Colebrooke, R. L. et al., 2002. Chronic hypoxia remodels voltage-gated Ca2+ entry in a human airway chemoreceptor cell line. Neuroscience Letters 318 (2), pp.69-72. (10.1016/S0304-3940(01)02479-X)
- Kemp, P. J. , Hartness, M. E. and Peers, C. 2002. Oxygen sensing by human recombinant large conductance, calcium-activated potassium channels:regulation by chronic hypoxia. In: Pequignot, J. et al., Chemoreception: From Cellular Signaling to Functional Plasticity. Advances in Experimental Medicine and Biology Springer. , pp.573-581.
- Kemp, P. J. et al. 2002. Airway chemotransduction: from oxygen sensor to cellular effector. American Journal of Respiratory and Critical Care Medicine 166 , pp.S17-S24. (10.1164/rccm.2206009)
- Kemp, P. J. et al. 2002. Oxygen sensing by human recombinant tandem-P domain potassium channels. In: Pequinot, J. et al., Chemoreception: From Cellular Signaling to Functional Plasticity. Advances in Experimental Medicine and Biology Springer. , pp.201-208. (10.1007/978-1-4419-9280-2_26)
- Plant, L. D. et al., 2002. Hypoxic depolarization of cerebellar granule neurons by specific inhibition of TASK-1. Stroke 33 (9), pp.2324-2328. (10.1161/01.STR.0000027440.68031.B0)
- Searle, G. J. et al., 2002. Lack of contribution of mitochondrial electron transport to acute O2 sensing in model airway chemoreceptors. Biochemical and Biophysical Research Communications 291 (2), pp.332-337. (10.1006/bbrc.2002.6428)
2001
- Hartness, M. E. et al., 2001. Combined antisense and pharmacological approaches implicate hTASK as an airway O2-sensing K+ channel. Journal of Biological Chemistry , pp.26499-26508. (10.1074/jbc.M010357200)
- Baines, D. L. , MacGregor, G. G. and Kemp, P. J. 2001. Fatty acid modulation and sequence identity of fetal guinea pig alveolar type II cell amiloride-sensitive Na+ channel. Biochemical and Biophysical Research Communications 288 (3), pp.727-735. (10.1006/bbrc.2001.5828)
- Kemp, P. J. et al. 2001. Re-evaluating the Na+ conductance of adult rat alveolar type II pneumocytes: evidence for the involvement of cGMP-activated cation channels. The Journal of Physiology 536 (3), pp.693-701. (10.1111/j.1469-7793.2001.t01-1-00693.x)
- Lewis, A. et al., 2001. Recombinant hTASK1 Is an O2-sensitive K+ channel. Biochemical and Biophysical Research Communications 285 (5), pp.1290-1294. (10.1006/bbrc.2001.5310)
- O'Kelly, I. , Peers, C. and Kemp, P. J. 2001. NADPH oxidase does not account fully for O2-Sensing in model airway chemoreceptor cells. Biochemical and Biophysical Research Communications 283 (5), pp.1131-1134. (10.1006/bbrc.2001.4919)
- Peers, C. and Kemp, P. J. 2001. Acute oxygen sensing: diverse but convergent mechanisms in airway and arterial chemoreceptors. Respiratory Research 2 , pp.145-149. (10.1186/rr51)
2000
- Kemp, P. J. et al. 2000. O2-sensing by model airway chemoreceptors: hypoxic inhibition of K+ channels in H146 cells. In: Pequignot, J. et al., Chemoreception: From Cellular Signaling to Functional Plasticity. Advances in Experimental Medicine and Biology Springer. , pp.611-622. (10.1007/978-1-4419-9280-2_26)
- O'Kelly, I. , Lewis, A. and Kemp, P. J. 2000. O2 Sensing by Airway Chemoreceptor-derived cells protein kinase C activation reveals functional evidence for involvement of NADPH oxidase. Journal of Biological Chemistry 275 (11), pp.7684-7692. (10.1074/jbc.275.11.7684)
Articles
- Brouns, I. et al., 2026. Are pulmonary neuroepithelial bodies sensors for acute airway hypoxia implicated in the central regulation of breathing?. PLoS ONE 21 (6) e0351688. (10.1371/journal.pone.0351688)
- Choompoo, N. et al. 2021. Induced pluripotent stem cells derived from the developing striatum as a potential donor source for cell replacement therapy for Huntington disease. Cytotherapy 23 (2), pp.111-118. (10.1016/j.jcyt.2020.06.001)
- Grimes, L. et al. 2020. Drosophila taste neurons as an agonist-screening platform for P2X receptors. Scientific Reports 10 8292. (10.1038/s41598-020-65169-9)
- Smith-Geater, C. et al., 2020. Aberrant development corrected in adult-onset Huntington's disease iPSC-derived neuronal cultures via WNT signaling modulation. Stem Cell Reports 14 (3), pp.406-419. (10.1016/j.stemcr.2020.01.015)
- Garcia, V. J. et al., 2019. Huntington's disease patient-derived astrocytes display electrophysiological impairments and reduced neuronal support. Frontiers in Neuroscience 13 669. (10.3389/fnins.2019.00669)
- Telezhkin, V. et al. 2018. Kv7 channels are upregulated during striatal neuron development and promote maturation of human iPSC-derived neurons. Pflügers Archiv European Journal of Physiology 470 (9), pp.1359-1376. (10.1007/s00424-018-2155-7)
- Lim, R. G. et al., 2017. Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice. Nature Neuroscience 20 (5), pp.648-660. (10.1038/nn.4532)
- Kemp, P. J. et al. 2016. Improving and accelerating the differentiation and functional maturation of human stem cell-derived neurons: role of extracellular calcium and GABA. The Journal of Physiology 594 (22), pp.6583-6594. (10.1113/JP270655)
- Zhang, G. et al. 2016. The role of Kv1.2 channel in electrotaxis cell migration. Journal of Cellular Physiology 231 (6), pp.1375-1384. (10.1002/jcp.25259)
- Young, F. I. et al. 2016. Clonal heterogeneity in the neuronal and glial differentiation of dental pulp stem/progenitor cells. Stem Cells International 2016 1290561. (10.1155/2016/1290561)
- Telezhkin, V. et al., 2016. Forced cell-cycle exit and modulation of GABAA, CREB and GSK3β signaling promote functional maturation of induced pluripotent stem cell-derived neurons. American Journal of Physiology - Cell Physiology ajpcell.00166.2015. (10.1152/ajpcell.00166.2015)
- Yarova, P. L. et al. 2016. Inhaled calcilytics: effects on airway inflammation and remodeling. Respiratory Drug Delivery 1 , pp.1-12.
- Brennan, S. C. et al. 2016. The extracellular calcium-sensing receptor regulates human fetal lung development via CFTR. Scientific Reports 6 21975. (10.1038/srep21975)
- Schepelmann, M. et al. 2016. The vascular Ca2+-sensing receptor regulates blood vessel tone and blood pressure. American Journal of Physiology - Cell Physiology 310 (3), pp.C193-C204. (10.1152/ajpcell.00248.2015)
- Stephen P., B. , Telezhkin, V. and Kemp, P. 2016. Functional interactions between BKCa a-subunit and Annexin A5: implications in apoptosis. Oxidative Medicine and Cellular Longevity 2016 1607092. (10.1155/2016/1607092)
- Straccia, M. et al., 2015. Quantitative high-throughput gene expression profiling of human striatal development to screen stem cell-derived medium spiny neurons. Molecular Therapy - Methods & Clinical Development 2 15030. (10.1038/mtm.2015.30)
- Hänggi, P. et al., 2015. Functional plasticity of the N-methyl-d-aspartate receptor in differentiating human erythroid precursor cells. American Journal of Physiology - Cell Physiology 308 (12), pp.C993-C1007. (10.1152/ajpcell.00395.2014)
- Yarova, P. L. et al. 2015. Calcium-sensing receptor antagonists abrogate airways hyperresponsiveness and inflammation in allergic asthma. Science Translational Medicine 7 (284) 284ra60. (10.1126/scitranslmed.aaa0282)
- Kemp, P. J. and Telezhkin, V. 2014. Oxygen sensing by the carotid body: is it all just rotten eggs?. Antioxidants & Redox Signaling 20 (5), pp.794-804. (10.1089/ars.2013.5377)
- Lembrechts, R. et al., 2013. Functional expression of the multimodal extracellular calcium-sensing receptor in pulmonary neuroendocrine cells. Journal of Cell Science 126 (19), pp.4490-4501. (10.1242/jcs.131656)
- Matsa, E. et al., 2013. Allele-specific RNA interference rescues the long-QT syndrome phenotype in human-induced pluripotency stem cell cardiomyocytes. European Heart Journal 35 (16), pp.1078-1087. (10.1093/eurheartj/eht067)
- Brennan, S. C. et al. 2013. Fetal calcium regulates branching morphogenesis in the developing human and mouse lung: involvement of voltage-gated calcium channels. PLoS ONE 8 (11), pp.e80294. (10.1371/journal.pone.0080294)
- Rushton, D. J. et al. 2013. Stimulation of GABA-induced Ca2+ influx enhances maturation of human induced pluripotent stem cell-derived neurons. PLoS ONE 8 (11), pp.e81031. (10.1371/journal.pone.0081031)
- Shore, A. et al. 2013. A Comparative approach to understanding tissue-specific expression of uncoupling protein 1 expression in adipose tissue. Frontiers in Genetics 3 304. (10.3389/fgene.2012.00304)
- Shore, A. et al. 2013. Cold-induced changes in gene expression in brown adipose tissue, white adipose tissue and liver. PLoS ONE 8 (7) e68933. (10.1371/journal.pone.0068933)
- Mattis, V. B. et al., 2012. Induced pluripotent stem cells from patients with Huntington's Disease show CAG-repeat-expansion-associated phenotypes. Cell Stem Cell 11 (2), pp.264-278. (10.1016/j.stem.2012.04.027)
- Riccardi, D. and Kemp, P. J. 2012. The calcium-sensing receptor beyond extracellular calcium homeostasis: Conception, development, adult physiology, and disease. Annual Review of Physiology 74 , pp.271-297. (10.1146/annurev-physiol-020911-153318)
- Wray, S. et al., 2012. Creation of an open-access, mutation-defined fibroblast resource for neurological disease research. PLoS ONE 7 (8) e43099. (10.1371/journal.pone.0043099)
- Cayzac, S. H. et al., 2011. Spermine attenuates carotid body glomus cell oxygen sensing by inhibiting L-type Ca2+ channels. Respiratory Physiology & Neurobiology 175 (1), pp.80-89. (10.1016/j.resp.2010.09.009)
- Finney, B. et al. 2011. An exon 5-less splice variant of the extracellular calcium-sensing receptor rescues absence of the full-length receptor in the developing mouse lung. Experimental Lung Research 37 (5), pp.269-278. (10.3109/01902148.2010.545471)
- Kelly, C. et al. 2011. Medical terminations of pregnancy: A viable source of tissue for cell replacement therapy for neurodegenerative disorders. Cell Transplantation 20 (4), pp.503-513. (10.3727/096368910X546580)
- Telezhkin, V. et al., 2011. Cysteine residue 911 in C-terminal tail of human BKCaα channel subunit is crucial for its activation by carbon monoxide. Pflugers Archiv-European Journal of Physiology 461 (6), pp.665-675. (10.1007/s00424-011-0924-7)
- Wilkinson, W. J. et al. 2011. Alveolar epithelial CNGA1 channels mediate cGMP-stimulated, amiloride-insensitive, lung liquid absorption. Pflügers Archiv European Journal of Physiology 462 (2), pp.267-279. (10.1007/s00424-011-0971-0)
- Wilkinson, W. J. and Kemp, P. J. 2011. Carbon monoxide: an emerging regulator of ion channels. The Journal of Physiology 589 (13), pp.3055-3062. (10.1113/jphysiol.2011.206706)
- Wilkinson, W. J. and Kemp, P. J. 2011. The carbon monoxide donor, CORM-2, is an antagonist of ATP-gated, human P2X4 receptors. Purinergic Signalling 7 (1), pp.57-64. (10.1007/s11302-010-9213-8)
- Shore, A. et al. 2010. Role of Ucp1 enhancer methylation and chromatin remodelling in the control of Ucp1 expression in murine adipose tissue. Diabetologia 53 (6), pp.1164-1173. (10.1007/s00125-010-1701-4)
- Telezhkin, V. et al., 2010. Mechanism of inhibition by hydrogen sulfide of native and recombinant BKCa channels. Respiratory Physiology & Neurobiology 172 (3), pp.169-178. (10.1016/j.resp.2010.05.016)
- Warburton, D. et al., 2010. Lung organogenesis. Current Topics in Developmental Biology 90 , pp.73-158. (10.1016/S0070-2153(10)90003-3)
- De Proost, I. et al., 2009. Purinergic signaling in the pulmonary neuroepithelial body microenvironment unraveled by live cell imaging. The FASEB Journal 23 (4), pp.1153-1160. (10.1096/fj.08-109579)
- Kemp, P. J. et al. 2009. Enzyme-linked oxygen sensing by potassium channels. Annals of the New York Academy of Sciences 1177 , pp.112-118. (10.1111/j.1749-6632.2009.05025.x)
- Riccardi, D. et al. 2009. Novel regulatory aspects of the extracellular Ca2+-sensing receptor, CaR. Pflugers Archiv-European Journal of Physiology 458 (6), pp.1007-1022. (10.1007/s00424-009-0681-z)
- Telezhin, V. et al., 2009. Hydrogen Sulfide inhibits human BKCa channels. Advances in Experimental Medicine and Biology 648 , pp.65-72. (10.1007/978-90-481-2259-2_7)
- Wilkinson, W. J. et al. 2009. Carbon monoxide is a rapid modulator of recombinant and native P2X(2) ligand-gated ion channels. British Journal of Pharmacology 158 (3), pp.862-871. (10.1111/j.1476-5381.2009.00354.x)
- De Proost, I. et al., 2008. Functional live cell imaging of the pulmonary neuroepithelial body microenvironment. American Journal of Respiratory Cell and Molecular Biology 39 (2), pp.180-189. (10.1165/rcmb.2008-0011OC)
- Finney, B. et al. 2008. Regulation of mouse lung development by the extracellular calcium-sensing receptor, CaR. Journal of Physiology 586 (24), pp.6007-6019. (10.1113/jphysiol.2008.161687)
- Timmermans, J. P. et al., 2008. Expression of P2X receptors in LAD-2 cells and human lung mast cells [Abstract]. Purinergic Signalling 4 (S1), pp.S159. (10.1007/s11302-008-9116-0)
- Wilkinson, W. J. et al. 2008. Carbon monoxide is a rapid modulator of recombinant and native P2X2 ligand-gated ion channels [Abstract]. Purinergic Signalling 4 (S1), pp.26. (10.1007/s11302-008-9116-0)
- Williams, S. E. et al., 2008. A structural motif in the C-terminal tail of slo1 confers carbon monoxide sensitivity to human BKCa channels. Pflugers Archiv-European Journal of Physiology 456 (3), pp.561-572. (10.1007/s00424-007-0439-4)
- Dvorak, M. M. et al., 2007. Thiazide Diuretics Directly Induce Osteoblast Differentiation and Mineralized Nodule Formation by Interacting with a Sodium Chloride Co-Transporter in Bone. Journal of the American Society of Nephrology 18 (9), pp.2509-2516. (10.1681/ASN.2007030348)
- Kemp, P. J. and Peers, C. 2007. Oxygen sensing by ion channels. Essays in Biochemistry 43 , pp.77-90. (10.1042/bse0430077)
- Joannides, A. J. et al., 2007. Environmental signals regulate lineage choice and temporal maturation of neural stem cells from human embryonic stem cells. Brain 130 (5), pp.1263-1275. (10.1093/brain/awm070)
- Buckler, K. J. et al., 2006. Discussion. Novartis Foundation Symposium 272 , pp.228-233.
- Chandel, N. S. et al., 2006. Discussion. Novartis Foundation Symposium 272 , pp.151-156.
- Duchen, M. et al., 2006. Discussion. Novartis Foundation Symposium 272 , pp.100-105.
- Joannides, A. J. et al., 2006. A scaleable and defined system for generating neural stem cells from human embryonic stem cells. Stem Cells 25 (3), pp.731-737. (10.1634/stemcells.2006-0562)
- Kemp, P. J. 2006. Detecting acute changes in oxygen: will the real sensor please stand up?. Experimental Physiology 91 (5), pp.829-834. (10.1113/expphysiol.2006.034587)
- Kemp, P. J. et al. 2006. General discussion III. Novartis Foundation Symposium 272 , pp.214-217.
- Kemp, P. J. et al. 2006. General discussion II. Novartis Foundation Symposium (272), pp.131-140.
- Kummer, W. et al., 2006. Discussion. Novartis Foundation Symposium 272 , pp.114-118.
- Peers, C. et al., 2006. General discussion I. Novartis Foundation Symposium (272), pp.33-36.
- Aley, P. K. et al., 2005. Hypoxic modulation of Ca2+ signaling in human venous endothelial cells: MULTIPLE ROLES FOR REACTIVE OXYGEN SPECIES. Journal of Biological Chemistry 280 (14), pp.13349-13354. (10.1074/jbc.M413674200)
- Bourke, S. et al., 2005. Development of a lung slice preparation for recording ion channel activity in alveolar epithelial type I cells. Respiratory Research 6 40. (10.1186/1465-9921-6-40)
- Brazier, S. P. et al., 2005. Cloning of the human TASK-2 (KCNK5) promoter and its regulation by chronic hypoxia. Biochemical and Biophysical Research Communications 336 (4), pp.1251-1258. (10.1016/j.bbrc.2005.09.007)
- Kemp, P. J. 2005. Hemeoxygenase-2 as an O2 sensor in K+ channel-dependent chemotransduction. Biochemical and Biophysical Research Communications 338 (1), pp.648-652. (10.1016/j.bbrc.2005.08.110)
- Miller, P. , Kemp, P. J. and Peers, C. 2005. Structural requirements for O2 sensing by the human tandem-P domain channel, hTREK1. Biochemical and Biophysical Research Communications 331 (4), pp.1253-1256. (10.1016/j.bbrc.2005.04.042)
- Williams, S. E. J. et al., 2004. Hemoxygenase-2 is an oxygen sensor for a calcium-sensitive potassium channel. Science , pp.2993-2997. (10.1126/science.1105010)
- Miller, P. , Peers, C. and Kemp, P. J. 2004. Polymodal regulation of hTREK1 by pH, arachidonic acid, and hypoxia: Physiological impact in acidosis and alkalosis. American Journal of Physiology - Cell Physiology 286 (2), pp.C272-C282. (10.1152/ajpcell.00334.2003)
- Hammond, L. C. et al., 2004. Chronic hypoxia up-regulates expression of adenosine A1 receptors in DDT1-MF2 cells. Biochemical Pharmacology 67 (3), pp.421-426. (10.1016/j.bcp.2003.09.003)
- Kemp, P. J. , Iles, D. and Peers, C. 2004. Oxygen sensing by human recombinant K+ channels: assessment of the use of stable cell lines. Methods in Enzymology 381 , pp.257-274. (10.1016/S0076-6879(04)81018-8)
- Kemp, P. J. and Kim, K. 2004. Spectrum of ion channels in alveolar epithelial cells: implications for alveolar fluid balance. AJP: Lung Cellular and Molecular Physiology 287 (3), pp.L460-L464. (10.1152/ajplung.00191.2004)
- Kemp, P. J. and Peers, C. 2004. Assessment of oxygen sensing by model airway and arterial chemoreceptors. Methods in Enzymology 381 , pp.3-25. (10.1016/S0076-6879(04)81001-2)
- Kemp, P. J. et al. 2004. Regulation of recombinant human brain tandem P domain K+ channels by hypoxia: A role for O2 in the control of neuronal excitability?. Journal of Cellular and Molecular Medicine 8 (1), pp.38-44. (10.1111/j.1582-4934.2004.tb00258.x)
- Mason, H. S. , Bourke, S. and Kemp, P. J. 2004. Selective modulation of ligand-gated P2X purinoceptor channels by acute hypoxia is mediated by reactive oxygen species. Molecular Pharmacology 66 (6), pp.1525-1535. (10.1124/mol.104.000851)
- Peers, C. and Kemp, P. J. 2004. Ion channel regulation by chronic hypoxia in models of acute oxygen sensing. Cell Calcium 36 (3-4), pp.341-348. (10.1016/j.ceca.2004.02.005)
- Williams, S. E. et al., 2004. siRNA knock-down of γ-glutamyl transpeptidase does not affect hypoxic K+ channel inhibition. Biochemical and Biophysical Research Communications 314 (1), pp.63-68. (10.1016/j.bbrc.2003.12.052)
- Hartness, M. E. et al., 2003. Post-transcriptional control of human maxiK potassium channel activity and acute oxygen sensitivity by chronic hypoxia. Journal of Biological Chemistry , pp.51422-51432. (10.1074/jbc.M309463200)
- Kemp, P. J. , Peers, C. and Lewis, A. 2003. Oxygen sensing by human recombinant large conductance, calcium-activated potassium channels. Regulation by acute hypoxia. Advances in Experimental Medicine and Biology 536 , pp.209-215.
- Kemp, P. J. et al. 2003. Acute oxygen sensing in cellular models: relevance to the physiology of pulmonary neuroepithelial and carotid bodies. Anatomical Record - Part A Discoveries in Molecular, Cellular, and Evolutionary Biology 270A (1), pp.41-50. (10.1002/ar.a.10008)
- Miller, P. et al., 2003. Acute hypoxia occludes hTREK-1 modulation: re-evaluation of the potential role of tandem P domain K+ channels in central neuroprotection. The Journal of Physiology 548 (1), pp.31-37. (10.1113/jphysiol.2003.040048)
- Lewis, A. et al., 2002. Hypoxia inhibits human recombinant large conductance, Ca2+-activated K+ (maxi-K) channels by a mechanism which is membrane delimited and Ca2+ sensitive. The Journal of Physiology 540 (3), pp.771-780. (10.1113/jphysiol.2001.013888)
- Colebrooke, R. L. et al., 2002. Chronic hypoxia remodels voltage-gated Ca2+ entry in a human airway chemoreceptor cell line. Neuroscience Letters 318 (2), pp.69-72. (10.1016/S0304-3940(01)02479-X)
- Kemp, P. J. et al. 2002. Airway chemotransduction: from oxygen sensor to cellular effector. American Journal of Respiratory and Critical Care Medicine 166 , pp.S17-S24. (10.1164/rccm.2206009)
- Plant, L. D. et al., 2002. Hypoxic depolarization of cerebellar granule neurons by specific inhibition of TASK-1. Stroke 33 (9), pp.2324-2328. (10.1161/01.STR.0000027440.68031.B0)
- Searle, G. J. et al., 2002. Lack of contribution of mitochondrial electron transport to acute O2 sensing in model airway chemoreceptors. Biochemical and Biophysical Research Communications 291 (2), pp.332-337. (10.1006/bbrc.2002.6428)
- Hartness, M. E. et al., 2001. Combined antisense and pharmacological approaches implicate hTASK as an airway O2-sensing K+ channel. Journal of Biological Chemistry , pp.26499-26508. (10.1074/jbc.M010357200)
- Baines, D. L. , MacGregor, G. G. and Kemp, P. J. 2001. Fatty acid modulation and sequence identity of fetal guinea pig alveolar type II cell amiloride-sensitive Na+ channel. Biochemical and Biophysical Research Communications 288 (3), pp.727-735. (10.1006/bbrc.2001.5828)
- Kemp, P. J. et al. 2001. Re-evaluating the Na+ conductance of adult rat alveolar type II pneumocytes: evidence for the involvement of cGMP-activated cation channels. The Journal of Physiology 536 (3), pp.693-701. (10.1111/j.1469-7793.2001.t01-1-00693.x)
- Lewis, A. et al., 2001. Recombinant hTASK1 Is an O2-sensitive K+ channel. Biochemical and Biophysical Research Communications 285 (5), pp.1290-1294. (10.1006/bbrc.2001.5310)
- O'Kelly, I. , Peers, C. and Kemp, P. J. 2001. NADPH oxidase does not account fully for O2-Sensing in model airway chemoreceptor cells. Biochemical and Biophysical Research Communications 283 (5), pp.1131-1134. (10.1006/bbrc.2001.4919)
- Peers, C. and Kemp, P. J. 2001. Acute oxygen sensing: diverse but convergent mechanisms in airway and arterial chemoreceptors. Respiratory Research 2 , pp.145-149. (10.1186/rr51)
- O'Kelly, I. , Lewis, A. and Kemp, P. J. 2000. O2 Sensing by Airway Chemoreceptor-derived cells protein kinase C activation reveals functional evidence for involvement of NADPH oxidase. Journal of Biological Chemistry 275 (11), pp.7684-7692. (10.1074/jbc.275.11.7684)
Book sections
- Kemp, P. J. and Peers, C. 2009. Enzyme-linked acute oxygen sensing in airway and arterial chemoreceptors. In: Gonzalez, C. , Nurse, C. A. and Peers, C. eds. Arterial Chemoreceptors. Advances in Experimental Medicine and Biology Vol. 648.Netherlands: Springer Netherlands. , pp.39-48. (10.1007/978-90-481-2259-2_4)
- Kemp, P. J. et al. 2006. In search of the acute oxygen sensor: Functional proteomics and acute regulation of large-conductance, calcium-activated potassium channels by hemeoxygenase-2. In: Hayashida, Y. , Gonzalez, C. and Kondo, H. eds. The Arterial Chemoreceptors. Vol. 580, Advances in Experimental Medicine and Biology Springer. , pp.137-146. (10.1007/0-387-31311-7_21)
- Kemp, P. J. et al. 2006. Functional proteomics of BK potassium channels: Defining the acute oxygen sensor. In: Chadwick, D. J. and Goode, J. eds. Signalling Pathways in Acute Oxygen Sensing: Novartis Foundation Symposium 272. Novartis Foundation Symposia Wiley-Blackwell. , pp.141-151. (10.1002/9780470035009.ch12)
- Peers, C. et al., 2006. Hypoxic regulation of Ca2+ signalling in astrocytes and endothelial cells. In: Chadwick, D. and Goode, J. eds. Signalling Pathways in Acute Oxygen Sensing: Novartis Foundation Symposium 272. Wiley-Blackwell. , pp.119-127. (10.1002/9780470035009.ch10)
- Peers, C. et al., 2006. Hypoxic regulation of Ca2+ signalling in astrocytes and endothelial cells. In: Hayashida, Y. , Gonzalez, C. and Konda, H. eds. The Arterial Chemoreceptors. Vol. 580, Advances in Experimental Medicine and Biology Kluwer. , pp.185-190. (10.1007/0-387-31311-7_28)
- Kemp, P. J. , Hartness, M. E. and Peers, C. 2002. Oxygen sensing by human recombinant large conductance, calcium-activated potassium channels:regulation by chronic hypoxia. In: Pequignot, J. et al., Chemoreception: From Cellular Signaling to Functional Plasticity. Advances in Experimental Medicine and Biology Springer. , pp.573-581.
- Kemp, P. J. et al. 2002. Oxygen sensing by human recombinant tandem-P domain potassium channels. In: Pequinot, J. et al., Chemoreception: From Cellular Signaling to Functional Plasticity. Advances in Experimental Medicine and Biology Springer. , pp.201-208. (10.1007/978-1-4419-9280-2_26)
- Kemp, P. J. et al. 2000. O2-sensing by model airway chemoreceptors: hypoxic inhibition of K+ channels in H146 cells. In: Pequignot, J. et al., Chemoreception: From Cellular Signaling to Functional Plasticity. Advances in Experimental Medicine and Biology Springer. , pp.611-622. (10.1007/978-1-4419-9280-2_26)
Conferences
- Brazier, S. P. et al. 2009. Cysteine residues in the C-terminal tail of the human BKCaα subunit are important for channel sensitivity to carbon monoxide. Presented at: International Society of Arterial Chemoreception. 17th Meeting Valladolid, Spain 1-5 July 2008. Arterial Chemoreceptors. Advances in Experimental Medicine and Biology Vol. 648. Netherlands: Springer Netherlands. , pp.49-56. (10.1007/978-90-481-2259-2_5)
- Cayzac, S. et al., 2009. Effects of the polyamine spermine on arterial chemoreception. Presented at: International Society of Arterial Chemoreception. 17th Meeting Valladolid, Spain 1-5 July 2008. Published in: Gonzalez, C. , Nurse, C. A. and Peers, C. eds. Arterial chemoreceptors. Advances in Experimental Medicine and Biology Vol. 648. Netherlands: Springer Netherlands. , pp.97-104. (10.1007/978-90-481-2259-2_11)