Mrs Jawaria Aziz

Publication

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Research

My research is embedded within BARNARD Phase II (2021–2026; funded by the Ineos Oxford Institute), an international consortium dedicated to improving the detection, surveillance, and clinical management of neonatal sepsis.

I lead the bioinformatic analysis of Gram-positive bacteria at Cardiff University, where I design, implement, and oversee large-scale genomic workflows. I have hands-on expertise in whole-genome sequencing using short-read (Illumina) and long-read (Oxford Nanopore) platforms, enabling hybrid genome assemblies. My principal research interest lies in analysing large-scale genomic datasets to elucidate pathogen origins and transmission pathways, support genomic surveillance, track hospital outbreaks, and identify the evolutionary mechanisms underpinning multidrug resistance in Gram-positive pathogens.

My overarching aim is to translate genomic insights into evidence-based interventions that strengthen antimicrobial stewardship and improve outcomes for vulnerable neonatal populations globally. The findings from this work have the potential to inform future interventional studies aimed at optimising antimicrobial therapy and enhancing infection prevention and control practices to effectively manage neonatal sepsis.

Supervisors

Brad Spiller

Full Professor