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Chris Course   BSc MBBCh

Dr Chris Course



Clinical Research Fellow

School of Medicine

Main Hospital Building, Room 6FT-164, University Hospital of Wales, Heath Park, Cardiff, CF14 4XN


I graduated from Cardiff Univesrity Medical School in 2011 during which time I also completed an intercalated BSc in Pyschology & Medicine. Since graduation, I entered paediatric training in 2014, and I am currently on the subspeciality training programme for neonatology run by the Royal College of Paediatrics and Child Health.

At present I am taking three years away from clinical work to complete a PhD investigating the biochemical mediators of respiratory pathology in school aged survivors of premature birth. This work is mainly focused on proteomic and metabolomic analysis of respiratory and urine samples taken from a large cohort of children who participated in the RHiNO (Respiratory Health Outcomes in Neonates) study. I am also a member of the team undertaking two-year follow up for infants enrolled on the AZTEC (Azithromcyin for Chronic Lung Disease of Prematurity) trial, which is examining the use of early azithromycin to prevent chronic lung disease of prematurity.












Premature birth acocunts for approximately 10% of all live births and represents a substantial health interest. Infants born extremely prematurely (<28 weeks completed gestation) are at high risk for early mortality and longer term morbidity, with increased repsiratory symptoms and neurodevelopmental problems. Those infants born less premature still have an increased risk of longer term morbidity.

My area of interest relates to the early and long term respiratroy outcomes for infants born prematurely. My current research project is examining whether there is a detectable biochemical change in school age children born prematurely with reduced lung function, compared to those preterm born children with better lung function and term match controls. To undertake this I am analsying proteomic and metabolomic data taken as part of a large clinical study (RHINO: Respiratory Health Outcomes for Neonates). This work is being supervised by Professor Sailesh Kotecha, Dr Sarah Kotecha and Dr John Watkins. 


2021 - 2024: Clinical Research Fellow/PhD Student, Department of Child Health, School of Medicine, Cardiff University, UK

2019 - 2025: Neonatalogy Speciality Trainee, Health Education and Improvement Wales, UK

2014 - 2019: Paediatric Speciality Trainee, Health Education and Improvement Wales, UK

2013 - 2014: Clinical Fellow, Department of Neonatology, University Hospital of Wales, Cardiff, UK

2011 - 2013: Foundation Programme Trainee, Wales Deanery, UK

2005 - 2011: Undergraduate, School of Medicine, Cardiff, UK

Professional memberships

  • Member of the Royal College of Paediatrics and Child health
  • British Associaiton of Perinatal Medicine
  • British Paediatric Respiratory Society


Sailesh Kotecha

Sailesh Kotecha

Clinical Professor, School of Medicine

Research themes


  • Neonatology
  • Respiratory diseases