Overview
Amy Houseman is a current PhD student under the supervision of Prof. Jeremy Cheadle, Dr Hannah West, and Prof. Julian Sampson. Her current PhD research title focuses on 'Identifying risk alleles for colorectal cancer and determining their clinical utility'. Amy has experience in bioinformatics including WES/WGS and haloplex analyses in the search for high penetrant variants relating to colorectal polyposis. Her research interests include genomic applications for rare human genetic diseases.
Prior to her PhD, Amy was a member of Dr Katja Eckl's human genetics group at Edge Hill University. It was here that she worked on the genetics of Autosomal Recessive Congenital Ichthyosis; analysing Sanger sequence data from patients to produce the undergraduate dissertation 'Variant detection of human Sanger AB1 trace files using a cost-free linux-based pipeline' which can be found here.
During her BSc Genetics (Honours), Amy completed a year-long placement as a bioinformatics research assisant with the Big Data Biology Lab at Fudan University, Shanghai under the laboratory of Professor Luis Pedro Coelho. Amy's work at Fudan University involved characterising small proteins from large metagenomic datasets. Amy also worked on bridging the knowledge gap between how bacteria in the human gut may interact with the function of psychotropic drugs.
Publication
2025
- Wills, C. et al. 2025. Relationship between inherited genetic variation and survival from colorectal cancer stratified by tumour location. Scientific Reports 15, article number: 2423. (10.1038/s41598-024-77870-0)
2023
- Wills, C. et al. 2023. Relationship between 233 colorectal cancer risk loci and survival in 1,926 patients with advanced disease. BJC Reports 1, article number: 2. (10.1038/s44276-023-00003-z)
Articles
- Wills, C. et al. 2025. Relationship between inherited genetic variation and survival from colorectal cancer stratified by tumour location. Scientific Reports 15, article number: 2423. (10.1038/s41598-024-77870-0)
- Wills, C. et al. 2023. Relationship between 233 colorectal cancer risk loci and survival in 1,926 patients with advanced disease. BJC Reports 1, article number: 2. (10.1038/s44276-023-00003-z)
Research
Current researcher on "Genetic mechanisms in polyposis of the bowel" 12/WA/0071. IRAS 87399 - Chief Investigator Dr Hannah West.
Funded by Cancer Research Wales.
Thesis
Funding sources
PhD funded by Cancer Research Wales.
Teaching
Regularly supervise medical students on their week long SSC projects.
Supervisor for two placement year students.
Engagement
Part of the most recent Cancer Research Wales campaign: https://www.cancerresearch.wales/news-and-updates/cymruunited
Contact Details
Sir Geraint Evans Cardiovascular Research Building, Floor 1, Room C/16, University Hospital of Wales, Heath Park, Cardiff, CF14 4XN