Dr Francesco Bedogni

2025

• Wang, T., Sharp, M., Morella, I., Bedogni, F., Trajkovski, V., Brambilla, R. and Syed, Y. A. 2025. Mice with 16p11.2 deletion and duplication show alterations in biological processes associated with white matter. International Journal of Molecular Sciences 26(2), article number: 573. (10.3390/ijms26020573)

2024

• Frasca, A. et al. 2024. Neural precursor cells rescue symptoms of Rett syndrome by activation of the Interferon γ pathway.. EMBO Molecular Medicine 16(12), pp. 3218-3246. (10.1038/s44321-024-00144-9)
• Bak, A. et al. 2024. Temporal dynamics of neocortical development in organotypic mouse brain cultures: a comprehensive analysis. Journal of Neurophysiology 132(3), pp. 1038-1055. (10.1152/jn.00178.2024)

2021

• Bedogni, F. and Hevner, R. F. 2021. Cell-type-specific gene expression in developing mouse neocortex: intermediate progenitors implicated in axon development. Frontiers in Molecular Neuroscience 14, article number: 686034. (10.3389/fnmol.2021.686034)
• Colombo, E. et al. 2021. Dysregulated copper transport in multiple sclerosis may cause demyelination via astrocytes. Proceedings of the National Academy of Sciences 118(27), article number: e2025804118. (10.1073/pnas.2025804118)
• Oleari, R. et al. 2021. A novel SEMA3G mutation in two siblings affected by syndromic GnRH deficiency. Neuroendocrinology 111(5), pp. 421-441. (10.1159/000508375)
• Scaramuzza, L. et al. 2021. The enhancement of activity rescues the establishment of Mecp2 null neuronal phenotypes. EMBO Molecular Medicine 13(4), article number: e12433. (10.15252/emmm.202012433)

2019

• Zhang, D. et al. 2019. Towards a consensus on developmental regression. Neuroscience and Biobehavioral Reviews 107, pp. 3-5. (10.1016/j.neubiorev.2019.08.014)
• Frasca, A., Bedogni, F. and Landsberger, N. 2019. Progress in the development of in vivo redox measurements: New tools for longitudinal studies in Rett syndrome. Neuroscience and Biobehavioral Reviews 104, pp. 28-29. (10.1016/j.neubiorev.2019.06.014)
• Gandaglia, A. et al. 2019. A novel Mecp2Y120D knock-in model displays similar behavioral traits but distinct molecular features compared to the Mecp2-null mouse implying precision medicine for the treatment of Rett syndrome. Molecular Neurobiology 56(7), pp. 4838-4854. (10.1007/s12035-018-1412-2)

2018

• Elsen, G. E. et al. 2018. The epigenetic factor landscape of developing neocortex is regulated by transcription factors Pax6→ Tbr2→ Tbr1. Frontiers in Neuroscience 12, article number: 571. (10.3389/fnins.2018.00571)
• Cobolli Gigli, C. et al. 2018. Lack of Methyl-CpG binding protein 2 (MeCP2) affects cell fate refinement during embryonic cortical development. Cerebral Cortex 28(5), pp. 1846-1856. (10.1093/cercor/bhx360)

2017

• Schwarz, N. et al. 2017. Human cerebrospinal fluid promotes long-term neuronal viability and network function in human neocortical organotypic brain slice cultures. Scientific Reports 7(1), article number: 12249. (10.1038/s41598-017-12527-9)

2016

• Bedogni, F. et al. 2016. Defects during Mecp2 null embryonic cortex development precede the onset of overt neurological symptoms. Cerebral Cortex 26(6), pp. 2517-2529. (10.1093/cercor/bhv078)
• Mihalas, A. B., Elsen, G. E., Bedogni, F., Daza, R. A., Ramos-Laguna, K. A., Arnold, S. J. and Hevner, R. F. 2016. Intermediate progenitor cohorts differentially generate cortical layers and require Tbr2 for timely acquisition of neuronal subtype identity. Cell Reports 16(1), pp. 92-105. (10.1016/j.celrep.2016.05.072)
• D'Esposito, M. et al. 2016. MeCP2 related studies benefit from the use of CD1 as genetic background. PLoS ONE 11(4), article number: e0153473. (10.1371/journal.pone.0153473)
• Blum, R. et al. 2016. CDKL5 and shootin1 interact and concur in regulating neuronal polarization. PLoS ONE 11(2), article number: e0148634. (10.1371/journal.pone.0148634)

2015

• Rusconi, F. et al. 2015. LSD1 neurospecific alternative splicing controls neuronal excitability in mouse models of epilepsy. Cerebral Cortex 25(9), pp. 2729-2740. (10.1093/cercor/bhu070)

2014

• Bedogni, F., Rossi, R. L., Galli, F., Cobolli Gigli, C., Gandaglia, A., Kilstrup-Nielsen, C. and Landsberger, N. 2014. Rett syndrome and the urge of novel approaches to study MeCP2 functions and mechanisms of action. Neuroscience and Biobehavioral Reviews 46(Part 2), pp. 187-201. (10.1016/j.neubiorev.2014.01.011)

2013

• Colombo, E., Bedogni, F., Lorenzetti, I., Landsberger, N., Previtali, S. C. and Farina, C. 2013. Autocrine and immune cell-derived BDNF in human skeletal muscle: implications for myogenesis and tissue regeneration. Journal of Pathology 231(2), pp. 190-198. (10.1002/path.4228)
• Nelson, B. R., Hodge, R. D., Bedogni, F. and Hevner, R. F. 2013. Dynamic interactions between intermediate neurogenic progenitors and radial glia in embryonic mouse neocortex: potential role in Dll1-Notch signaling. Journal of Neuroscience 33(21), pp. 9122-9139. (10.1523/jneurosci.0791-13.2013)
• Elsen, G. E. et al. 2013. The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map. Proceedings of the National Academy of Sciences of the United States of America 110(10), pp. 4801-4086. (10.1073/pnas.1209076110)

2012

• Kilstrup-Nielsen, C., Rusconi, L., La Montanara, P., Ciceri, D., Bergo, A., Bedogni, F. and Landsberger, N. 2012. What we know and would like to know about CDKL5 and its involvement in epileptic encephalopathy. Neural Plasticity 2012, article number: 728267. (10.1155/2012/728267)

2010

• Koch, H. et al. 2010. Prostaglandin E2-induced synaptic plasticity in neocortical networks of organotypic slice cultures.. Journal of Neuroscience 30(35), pp. 11678-11687. (10.1523/jneurosci.4665-09.2010)
• Bedogni, R. et al. 2010. Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex.. Proceedings of the National Academy of Sciences 107(29), pp. 13129-13134. (10.1073/pnas.1002285107)
• Bedogni, F., Hodge, R. D., Nelson, B. R., Frederick, E. A., Shiba, N., Daza, R. A. and Hevner, R. F. 2010. Autism susceptibility candidate 2 (Auts2) encodes a nuclear protein expressed in developing brain regions implicated in autism neuropathology.. Gene Expression Patterns 10(1), pp. 9-15. (10.1016/j.gep.2009.11.005)

2009

• Kowalczyk, T. et al. 2009. Intermediate neuronal progenitors (basal progenitors) produce pyramidal-projection neurons for all layers of cerebral cortex.. Cerebral Cortex 19(10), pp. 2439-2450. (10.1093/cercor/bhn260)

2008

• Heng, J. I. et al. 2008. Neurogenin 2 controls cortical neuron migration through regulation of Rnd2.. Nature (10.1038/nature07198)

2007

• Fadda, P., Bedogni, F., Fresu, A., Collu, M., Racagni, G. and Riva, M. A. 2007. Reduction of corticostriatal glutamatergic fibers in basic fibroblast growth factor deficient mice is associated with hyperactivity and enhanced dopaminergic transmission.. Biological Psychiatry 62(3), pp. 235-242. (10.1016/j.biopsych.2006.08.003)

2006

• Fumagalli, F., Bedogni, F., Frasca, A., Di Pasquale, L., Racagni, G. and Riva, M. A. 2006. Corticostriatal up-regulation of activity-regulated cytoskeletal-associated protein expression after repeated exposure to cocaine.. Molecular Pharmacology 70(5), pp. 1726-1734. (10.1124/mol.106.026302)
• Molteni, R., Calabrese, F., Bedogni, F., Tongiorgi, E., Fumagalli, F., Giogio, R. and Rivea, M. A. 2006. Chronic treatment with fluoxetine up-regulates cellular BDNF mRNA expression in rat dopaminergic regions.. International Journal of Neuropsychopharmacology 9(3), pp. 307-317. (10.1017/s1461145705005766)

2005

• Fumagalli, F., Bedogni, F., Slotkin, T. A., Racagni, G. and Riva, M. A. 2005. Prenatal stress elicits regionally selective changes in basal FGF-2 gene expression in adulthood and alters the adult response to acute or chronic stress.. Neurobiology of Disease 20(3), pp. 731-737. (10.1016/j.nbd.2005.05.005)
• Riva, M. A., Molteni, R., Bedogni, F., Racagni, G. and Fumagalli, F. 2005. Emerging role of the FGF system in psychiatric disorders.. Trends in Pharmacological Sciences 26(5), pp. 228-231. (10.1016/j.tips.2005.03.001)

2004

• Fumagalli, F., Raffaella, M., Bedogni, F., Massimo, G., Perez, J., Racagni, G. and Riva, M. A. 2004. Quetiapine regulates FGF-2 and BDNF expression in the hippocampus of animals treated with MK-801.. NeuroReport 15(13), pp. 2109-2112. (10.1097/00001756-200409150-00022)
• Fumagalli, F., Bedogni, F., Perez, J., Racagni, G. and Riva, M. A. 2004. Corticostriatal brain-derived neurotrophic factor dysregulation in adult rats following prenatal stress.. European Journal of Neuroscience 20(15), pp. 1348-1354. (10.1111/j.1460-9568.2004.03592.x)

2003

• Fumagalli, F. et al. 2003. Effect of antipsychotic drugs on brain-derived neurotrophic factor expression under reduced N-methyl-D-aspartate receptor activity. Journal of Neuroscience Research 72(5), pp. 622-628. (10.1002/jnr.10609)
• Fumagalli, F., Bedogni, F., Maragnoli, M. E., Gennarelli, M., Perez, J., Racagni, G. and Riva, M. A. 2003. Dopaminergic D2 receptor activation modulates FGF-2 gene expression in rat prefrontal cortex and hippocampus.. Journal of Neuroscience Research 74(1), pp. 74-80. (10.1002/jnr.10733)