Dr Francesco Bedogni

2025

• van Loo, K. M. et al., 2025. What makes the human brain special - from cellular function to clinical translation. Journal of Neurophysiology 134 (4), pp.1197-1213. (10.1152/jn.00120.2025)
• Wang, T. et al. 2025. Mice with 16p11.2 deletion and duplication show alterations in biological processes associated with white matter. International Journal of Molecular Sciences 26 (2) 573. (10.3390/ijms26020573)

2024

• Bak, A. et al., 2024. Temporal dynamics of neocortical development in organotypic mouse brain cultures: a comprehensive analysis. Journal of Neurophysiology 132 (3), pp.1038-1055. (10.1152/jn.00178.2024)
• Frasca, A. et al., 2024. Neural precursor cells rescue symptoms of Rett syndrome by activation of the Interferon γ pathway.. EMBO Molecular Medicine 16 (12), pp.3218-3246. (10.1038/s44321-024-00144-9)

2021

• Bedogni, F. and Hevner, R. F. 2021. Cell-type-specific gene expression in developing mouse neocortex: intermediate progenitors implicated in axon development. Frontiers in Molecular Neuroscience 14 686034. (10.3389/fnmol.2021.686034)
• Colombo, E. et al., 2021. Dysregulated copper transport in multiple sclerosis may cause demyelination via astrocytes. Proceedings of the National Academy of Sciences 118 (27) e2025804118. (10.1073/pnas.2025804118)
• Oleari, R. et al., 2021. A novel SEMA3G mutation in two siblings affected by syndromic GnRH deficiency. Neuroendocrinology 111 (5), pp.421-441. (10.1159/000508375)
• Scaramuzza, L. et al., 2021. The enhancement of activity rescues the establishment of Mecp2 null neuronal phenotypes. EMBO Molecular Medicine 13 (4) e12433. (10.15252/emmm.202012433)

2019

• Frasca, A. , Bedogni, F. and Landsberger, N. 2019. Progress in the development of in vivo redox measurements: New tools for longitudinal studies in Rett syndrome. Neuroscience and Biobehavioral Reviews 104 , pp.28-29. (10.1016/j.neubiorev.2019.06.014)
• Gandaglia, A. et al., 2019. A novel Mecp2Y120D knock-in model displays similar behavioral traits but distinct molecular features compared to the Mecp2-null mouse implying precision medicine for the treatment of Rett syndrome. Molecular Neurobiology 56 (7), pp.4838-4854. (10.1007/s12035-018-1412-2)
• Zhang, D. et al., 2019. Towards a consensus on developmental regression. Neuroscience and Biobehavioral Reviews 107 , pp.3-5. (10.1016/j.neubiorev.2019.08.014)

2018

• Cobolli Gigli, C. et al., 2018. Lack of Methyl-CpG binding protein 2 (MeCP2) affects cell fate refinement during embryonic cortical development. Cerebral Cortex 28 (5), pp.1846-1856. (10.1093/cercor/bhx360)
• Elsen, G. E. et al., 2018. The epigenetic factor landscape of developing neocortex is regulated by transcription factors Pax6→ Tbr2→ Tbr1. Frontiers in Neuroscience 12 571. (10.3389/fnins.2018.00571)

2017

• Schwarz, N. et al., 2017. Human cerebrospinal fluid promotes long-term neuronal viability and network function in human neocortical organotypic brain slice cultures. Scientific Reports 7 (1) 12249. (10.1038/s41598-017-12527-9)

2016

• Bedogni, F. et al. 2016. Defects during Mecp2 null embryonic cortex development precede the onset of overt neurological symptoms. Cerebral Cortex 26 (6), pp.2517-2529. (10.1093/cercor/bhv078)
• Blum, R. et al., 2016. CDKL5 and shootin1 interact and concur in regulating neuronal polarization. PLoS ONE 11 (2) e0148634. (10.1371/journal.pone.0148634)
• D'Esposito, M. et al., 2016. MeCP2 related studies benefit from the use of CD1 as genetic background. PLoS ONE 11 (4) e0153473. (10.1371/journal.pone.0153473)
• Mihalas, A. B. et al., 2016. Intermediate progenitor cohorts differentially generate cortical layers and require Tbr2 for timely acquisition of neuronal subtype identity. Cell Reports 16 (1), pp.92-105. (10.1016/j.celrep.2016.05.072)

2015

• Rusconi, F. et al., 2015. LSD1 neurospecific alternative splicing controls neuronal excitability in mouse models of epilepsy. Cerebral Cortex 25 (9), pp.2729-2740. (10.1093/cercor/bhu070)

2014

• Bedogni, F. et al. 2014. Rett syndrome and the urge of novel approaches to study MeCP2 functions and mechanisms of action. Neuroscience and Biobehavioral Reviews 46 (Part 2), pp.187-201. (10.1016/j.neubiorev.2014.01.011)

2013

• Colombo, E. et al., 2013. Autocrine and immune cell-derived BDNF in human skeletal muscle: implications for myogenesis and tissue regeneration. Journal of Pathology 231 (2), pp.190-198. (10.1002/path.4228)
• Elsen, G. E. et al., 2013. The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map. Proceedings of the National Academy of Sciences of the United States of America 110 (10), pp.4801-4086. (10.1073/pnas.1209076110)
• Nelson, B. R. et al., 2013. Dynamic interactions between intermediate neurogenic progenitors and radial glia in embryonic mouse neocortex: potential role in Dll1-Notch signaling. Journal of Neuroscience 33 (21), pp.9122-9139. (10.1523/jneurosci.0791-13.2013)

2012

• Kilstrup-Nielsen, C. et al., 2012. What we know and would like to know about CDKL5 and its involvement in epileptic encephalopathy. Neural Plasticity 2012 728267. (10.1155/2012/728267)

2010

• Bedogni, F. et al. 2010. Autism susceptibility candidate 2 (Auts2) encodes a nuclear protein expressed in developing brain regions implicated in autism neuropathology.. Gene Expression Patterns 10 (1), pp.9-15. (10.1016/j.gep.2009.11.005)
• Bedogni, R. et al. 2010. Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex.. Proceedings of the National Academy of Sciences 107 (29), pp.13129-13134. (10.1073/pnas.1002285107)
• Koch, H. et al., 2010. Prostaglandin E2-induced synaptic plasticity in neocortical networks of organotypic slice cultures.. Journal of Neuroscience 30 (35), pp.11678-11687. (10.1523/jneurosci.4665-09.2010)

2009

• Kowalczyk, T. et al., 2009. Intermediate neuronal progenitors (basal progenitors) produce pyramidal-projection neurons for all layers of cerebral cortex.. Cerebral Cortex 19 (10), pp.2439-2450. (10.1093/cercor/bhn260)

2008

• Heng, J. I. et al., 2008. Neurogenin 2 controls cortical neuron migration through regulation of Rnd2.. Nature (10.1038/nature07198)

2007

• Fadda, P. et al., 2007. Reduction of corticostriatal glutamatergic fibers in basic fibroblast growth factor deficient mice is associated with hyperactivity and enhanced dopaminergic transmission.. Biological Psychiatry 62 (3), pp.235-242. (10.1016/j.biopsych.2006.08.003)

2006

• Fumagalli, F. et al., 2006. Corticostriatal up-regulation of activity-regulated cytoskeletal-associated protein expression after repeated exposure to cocaine.. Molecular Pharmacology 70 (5), pp.1726-1734. (10.1124/mol.106.026302)
• Molteni, R. et al., 2006. Chronic treatment with fluoxetine up-regulates cellular BDNF mRNA expression in rat dopaminergic regions.. International Journal of Neuropsychopharmacology 9 (3), pp.307-317. (10.1017/s1461145705005766)

2005

• Fumagalli, F. et al., 2005. Prenatal stress elicits regionally selective changes in basal FGF-2 gene expression in adulthood and alters the adult response to acute or chronic stress.. Neurobiology of Disease 20 (3), pp.731-737. (10.1016/j.nbd.2005.05.005)
• Riva, M. A. et al., 2005. Emerging role of the FGF system in psychiatric disorders.. Trends in Pharmacological Sciences 26 (5), pp.228-231. (10.1016/j.tips.2005.03.001)

2004

• Fumagalli, F. et al., 2004. Corticostriatal brain-derived neurotrophic factor dysregulation in adult rats following prenatal stress.. European Journal of Neuroscience 20 (15), pp.1348-1354. (10.1111/j.1460-9568.2004.03592.x)
• Fumagalli, F. et al., 2004. Quetiapine regulates FGF-2 and BDNF expression in the hippocampus of animals treated with MK-801.. NeuroReport 15 (13), pp.2109-2112. (10.1097/00001756-200409150-00022)

2003

• Fumagalli, F. et al., 2003. Effect of antipsychotic drugs on brain-derived neurotrophic factor expression under reduced N-methyl-D-aspartate receptor activity. Journal of Neuroscience Research 72 (5), pp.622-628. (10.1002/jnr.10609)
• Fumagalli, F. et al., 2003. Dopaminergic D2 receptor activation modulates FGF-2 gene expression in rat prefrontal cortex and hippocampus.. Journal of Neuroscience Research 74 (1), pp.74-80. (10.1002/jnr.10733)