Dr Ryan Bevan

BSc (Hons) MSc (Res) PhD (Cardiff)

2026

• Marsden, M. et al. 2026. Cytomegalovirus-induced T cell responses accelerate Alzheimer’s disease progression in mice. Brain 149 (9), pp.3214-3227. awag043. (10.1093/brain/awag043)
• Bevan, R. J. et al. 2026. Alzheimer's protection by PLCγ2 compacts plaques, redistributes microglia, and protects synapses in App NL ‐G‐F mice. Glia 74 (8) e70192. (10.1002/glia.70192)
• Kulmaganbetov, M. et al. 2026. The machine learning classification of retinal ganglion cell dendritic texture in a 3xTg-Alzheimer’s disease mouse model. Diagnostics 16 (16) 2672. (10.3390/diagnostics16162672)
• Bevan, R. J. et al. 2026. Early regional microglial remodelling in the hippocampus of the AppNL-G-F Alzheimer’s Model. Neuropathology and Applied Neurobiology 52 (3) e70082. (10.1111/nan.70082)
• Hughes, T. R. et al. 2026. The impact of the Lab4 probiotic on neurodegenerative processes in a murine Alzheimer’s disease model. Frontiers in Neuroscience 20 1791299. (10.3389/fnins.2026.1791299)

2025

• Zelek, W. M. et al. 2025. Brain-penetrant complement inhibition mitigates neurodegeneration in an Alzheimer's disease mouse model. Brain 148 (3), pp.941-954. (10.1093/brain/awae278)
• Kulmaganbetov, M. et al. 2025. SVM-Based optical detection of retinal ganglion cell apoptosis. Photonics 12 (2) 128. (10.3390/photonics12020128)
• Zelek, W. M. et al. 2025. Targeting novel anti‐complement drugs to the brain reduces complement activation and synapse loss, and improves cognition in a mouse model of dementia. Alzheimer's & Dementia: The Journal of the Alzheimer's Association 20 (S6)(10.1002/alz.090708)

2024

• Morgan, J. E. , Bevan, R. J. and Cimaglia, G. 2024. Retinal ganglion cell subtypes and their vulnerability in glaucoma. In: Jacobs, T. and Liton, P. B. eds. Glaucoma. Methods and Protocols. Vol. 2858, Methods in Molecular Biology New York, NY, USA: , pp.191-205. (10.1007/978-1-0716-4140-8_16)
• Bevan, R. J. et al. 2024. Improved DiOlistic labelling technique for neurons in situ: Detailed visualisation of dendritic spines and concurrent histochemical-detection in fixed tissue. Methods 229 , pp.82-93. (10.1016/j.ymeth.2024.06.009)
• Zelek, W. M. , Bevan, R. J. and Morgan, B. P. 2024. Targeting terminal pathway reduces brain complement activation, amyloid load and synapse loss, and improves cognition in a mouse model of dementia. Brain, Behavior, and Immunity 118 , pp.355-363. (10.1016/j.bbi.2024.03.017)

2023

• Cimaglia, G. et al. 2023. Gene gun DiOlistic labelling of retinal ganglion cells. In: Mead, B. ed. Retinal Ganglion Cells: Methods and Protocols. Vol. 2708, New York, NY: Springer. , pp.n/a. (10.1007/978-1-0716-3409-7_4)
• Reddaway, J. et al. 2023. Microglial morphometric analysis: so many options, so little consistency. Frontiers in Neuroinformatics 17 1211188. (10.3389/fninf.2023.1211188)
• Webberley, T. S. et al. 2023. Assessment of Lab4P probiotic effects on cognition in 3xTg-AD Alzheimer’s disease model mice and the SH-SY5Y neuronal cell line. International Journal of Molecular Sciences 24 (5) 4683. (10.3390/ijms24054683)

2022

• Carpanini, S. M. et al. 2022. Terminal complement pathway activation drives synaptic Loss in Alzheimer’s disease models. Acta Neuropathologica Communications 10 99. (10.1186/s40478-022-01404-w)
• Webberley, T. S. et al., 2022. The impact of probiotic supplementation on cognitive, pathological and metabolic markers in a transgenic mouse model of Alzheimer’s Disease. Frontiers in Neuroscience 16 843105. (10.3389/fnins.2022.843105)
• Kulmaganbetov, M. et al. 2022. Textural feature analysis of optical coherence tomography phantoms. Electronics 11 (4) 669. (10.3390/electronics11040669)

2020

• Bevan, R. 2020. Neuronal dendropathy in CNS degeneration: A new marker for protection and recovery. PhD Thesis , Cardiff University.
• Bevan, R. J. et al. 2020. Retinal ganglion cell degeneration correlates with hippocampal spine loss in experimental Alzheimer's disease. Acta Neuropathologica Communications 8 (1) 216. (10.1186/s40478-020-01094-2)
• Bevan, R. J. et al. 2020. OPA1 deficiency accelerates hippocampal synaptic remodelling and age-related deficits in learning and memory. Brain Communications 2 (2) fcaa101. (10.1093/braincomms/fcaa101)
• Griffith, L. et al., 2020. Substantial subpial cortical demyelination in progressive multiple sclerosis: have we underestimated the extent of cortical pathology?. Neuroimmunology and Neuroinflammation 7 , pp.51-67. (10.20517/2347-8659.2019.21)

2018

• Bevan, R. J. et al. 2018. Meningeal inflammation and cortical demyelination in acute multiple sclerosis. Annals of Neurology 84 (6), pp.829-842. (10.1002/ana.25365)

2017

• Bryant, A. H. et al., 2017. Expression and function of NOD-like receptors by human term gestation-associated tissues. Placenta 58 , pp.25-32. (10.1016/j.placenta.2017.07.017)