Publication
2026
- Liddiard, K. et al. 2026. Telomere-driven replicative crisis is driven by large-scale changes in genomic architecture. Genome Research (10.1101/gr.281373.125)
- Ngo, G. H. P. et al. 2026. Mitotic microhomology-mediated break-induced replication promotes chromoanasynthesis. Nature Communications (10.1038/s41467-026-70086-y)
2025
- Cleal, K. , Kearsey, A. and Baird, D. M. 2025. GW: ultra-fast chromosome-scale visualization of genomics data. Nature Methods 22 , pp.1390-1392. (10.1038/s41592-025-02749-5)
2022
- Liddiard, K. et al. 2022. POLQ suppresses genome instability and alterations in DNA repeat tract lengths. NAR Cancer 4 (3) zcac020. (10.1093/narcan/zcac020)
- Cleal, K. and Baird, D. 2022. Dysgu: efficient structural variant calling using short or long reads. Nucleic Acids Research 50 (9) e53. (10.1093/nar/gkac039)
- Geiller, H. E. et al. 2022. ATRX modulates the escape from a telomere crisis. Plos Genetics 18 (11) e1010485. (10.1371/journal.pgen.1010485)
2021
- Norris, K. et al. 2021. High-throughput STELA provides a rapid test for the diagnosis of telomere biology disorders. Human Genetics 140 , pp.945-955. (10.1007/s00439-021-02257-4)
- Liddiard, K. et al. 2021. Tracking telomere fusions through crisis reveals conflict between DNA transcription and the DNA Damage Response. NAR Cancer 3 (1) zcaa044. (10.1093/narcan/zcaa044)
2020
- Cleal, K. and Baird, D. 2020. Catastrophic endgames: emerging mechanisms of telomere-driven genomic instability. Trends in Genetics 36 (5), pp.347-359. (10.1016/j.tig.2020.02.001)
2019
- Escudero, L. et al., 2019. Telomere fusions associate with coding sequence and copy number alterations in CLL. Leukemia 33 , pp.2093-2097. (10.1038/s41375-019-0423-y)
- Cleal, K. et al. 2019. Chromothripsis during telomere crisis is independent of NHEJ, and consistent with a replicative origin. Genome Research 29 (5), pp.737-749. (10.1101/gr.240705.118)
- Liddiard, K. et al. 2019. DNA Ligase 1 is an essential mediator of sister chromatid telomere fusions in G2 cell cycle phase. Nucleic Acids Research 47 (5), pp.2402-2424. (10.1093/nar/gky1279)
2018
- Cleal, K. , Norris, K. and Baird, D. 2018. Telomere length dynamics and the evolution of cancer genome architecture. International Journal of Molecular Sciences 19 (2), pp.482-482. (10.3390/ijms19020482)
2015
- Cleal, K. 2015. Exploring the use of Quantum dots as quantitative model delivery agents for small molecules, peptides and proteins. PhD Thesis , Cardiff University.
2014
- Sayers, E. J. et al. 2014. Distal phenylalanine modification for enhancing cellular delivery of fluorophores, proteins and quantum dots by cell penetrating peptides. Journal of Controlled Release 195 , pp.55-62. (10.1016/j.jconrel.2014.07.055)
2013
- Cleal, K. et al. 2013. Endocytosis, intracellular traffic and fate of cell penetrating peptide based conjugates and nanoparticles. Current Pharmaceutical Design 19 (16), pp.2878-2894. (10.2174/13816128113199990297)
Articles
- Liddiard, K. et al. 2026. Telomere-driven replicative crisis is driven by large-scale changes in genomic architecture. Genome Research (10.1101/gr.281373.125)
- Ngo, G. H. P. et al. 2026. Mitotic microhomology-mediated break-induced replication promotes chromoanasynthesis. Nature Communications (10.1038/s41467-026-70086-y)
- Cleal, K. , Kearsey, A. and Baird, D. M. 2025. GW: ultra-fast chromosome-scale visualization of genomics data. Nature Methods 22 , pp.1390-1392. (10.1038/s41592-025-02749-5)
- Liddiard, K. et al. 2022. POLQ suppresses genome instability and alterations in DNA repeat tract lengths. NAR Cancer 4 (3) zcac020. (10.1093/narcan/zcac020)
- Cleal, K. and Baird, D. 2022. Dysgu: efficient structural variant calling using short or long reads. Nucleic Acids Research 50 (9) e53. (10.1093/nar/gkac039)
- Geiller, H. E. et al. 2022. ATRX modulates the escape from a telomere crisis. Plos Genetics 18 (11) e1010485. (10.1371/journal.pgen.1010485)
- Norris, K. et al. 2021. High-throughput STELA provides a rapid test for the diagnosis of telomere biology disorders. Human Genetics 140 , pp.945-955. (10.1007/s00439-021-02257-4)
- Liddiard, K. et al. 2021. Tracking telomere fusions through crisis reveals conflict between DNA transcription and the DNA Damage Response. NAR Cancer 3 (1) zcaa044. (10.1093/narcan/zcaa044)
- Cleal, K. and Baird, D. 2020. Catastrophic endgames: emerging mechanisms of telomere-driven genomic instability. Trends in Genetics 36 (5), pp.347-359. (10.1016/j.tig.2020.02.001)
- Escudero, L. et al., 2019. Telomere fusions associate with coding sequence and copy number alterations in CLL. Leukemia 33 , pp.2093-2097. (10.1038/s41375-019-0423-y)
- Cleal, K. et al. 2019. Chromothripsis during telomere crisis is independent of NHEJ, and consistent with a replicative origin. Genome Research 29 (5), pp.737-749. (10.1101/gr.240705.118)
- Liddiard, K. et al. 2019. DNA Ligase 1 is an essential mediator of sister chromatid telomere fusions in G2 cell cycle phase. Nucleic Acids Research 47 (5), pp.2402-2424. (10.1093/nar/gky1279)
- Cleal, K. , Norris, K. and Baird, D. 2018. Telomere length dynamics and the evolution of cancer genome architecture. International Journal of Molecular Sciences 19 (2), pp.482-482. (10.3390/ijms19020482)
- Sayers, E. J. et al. 2014. Distal phenylalanine modification for enhancing cellular delivery of fluorophores, proteins and quantum dots by cell penetrating peptides. Journal of Controlled Release 195 , pp.55-62. (10.1016/j.jconrel.2014.07.055)
- Cleal, K. et al. 2013. Endocytosis, intracellular traffic and fate of cell penetrating peptide based conjugates and nanoparticles. Current Pharmaceutical Design 19 (16), pp.2878-2894. (10.2174/13816128113199990297)
Thesis
- Cleal, K. 2015. Exploring the use of Quantum dots as quantitative model delivery agents for small molecules, peptides and proteins. PhD Thesis , Cardiff University.
