Mr Kez Cleal
Research Associate
Publication
2025
2022
- Liddiard, K., Aston-Evans, A. N., Cleal, K., Hendrickson, E. A. and Baird, D. M. 2022. POLQ suppresses genome instability and alterations in DNA repeat tract lengths. NAR Cancer 4(3), article number: zcac020. (10.1093/narcan/zcac020)
- Cleal, K. and Baird, D. 2022. Dysgu: efficient structural variant calling using short or long reads. Nucleic Acids Research 50(9), article number: e53. (10.1093/nar/gkac039)
- Geiller, H. E., Harvey, A., Jones, R. E., Grimstead, J. W., Cleal, K., Hendrickson, E. A. and Baird, D. 2022. ATRX modulates the escape from a telomere crisis. Plos Genetics 18(11), article number: e1010485. (10.1371/journal.pgen.1010485)
2021
- Norris, K. et al. 2021. High-throughput STELA provides a rapid test for the diagnosis of telomere biology disorders. Human Genetics 140, pp. 945-955. (10.1007/s00439-021-02257-4)
- Liddiard, K., Grimstead, J., Cleal, K., Evans, A. and Baird, D. 2021. Tracking telomere fusions through crisis reveals conflict between DNA transcription and the DNA Damage Response. NAR Cancer 3(1), article number: zcaa044. (10.1093/narcan/zcaa044)
2020
2019
- Escudero, L., Cleal, K., Ashelford, K., Fegan, C., Pepper, C., Liddiard, K. and Baird, D. M. 2019. Telomere fusions associate with coding sequence and copy number alterations in CLL. Leukemia 33, pp. 2093-2097. (10.1038/s41375-019-0423-y)
- Cleal, K., Jones, R. E., Grimstead, J. W., Hendrickson, E. A. and Baird, D. M. 2019. Chromothripsis during telomere crisis is independent of NHEJ, and consistent with a replicative origin. Genome Research 29(5), pp. 737-749. (10.1101/gr.240705.118)
- Liddiard, K., Ruis, B., Kan, Y., Cleal, K., Ashelford, K. E., Hendrickson, E. A. and Baird, D. M. 2019. DNA Ligase 1 is an essential mediator of sister chromatid telomere fusions in G2 cell cycle phase. Nucleic Acids Research 47(5), pp. 2402-2424. (10.1093/nar/gky1279)
2018
2015
2014
- Sayers, E. J., Cleal, K., Eissa, N. G., Watson, P. D. and Jones, A. T. 2014. Distal phenylalanine modification for enhancing cellular delivery of fluorophores, proteins and quantum dots by cell penetrating peptides. Journal of Controlled Release 195, pp. 55-62. (10.1016/j.jconrel.2014.07.055)
2013
Articles
- Cleal, K., Kearsey, A. and Baird, D. M. 2025. GW: ultra-fast chromosome-scale visualisation of genomics data. Nature Methods
- Liddiard, K., Aston-Evans, A. N., Cleal, K., Hendrickson, E. A. and Baird, D. M. 2022. POLQ suppresses genome instability and alterations in DNA repeat tract lengths. NAR Cancer 4(3), article number: zcac020. (10.1093/narcan/zcac020)
- Cleal, K. and Baird, D. 2022. Dysgu: efficient structural variant calling using short or long reads. Nucleic Acids Research 50(9), article number: e53. (10.1093/nar/gkac039)
- Geiller, H. E., Harvey, A., Jones, R. E., Grimstead, J. W., Cleal, K., Hendrickson, E. A. and Baird, D. 2022. ATRX modulates the escape from a telomere crisis. Plos Genetics 18(11), article number: e1010485. (10.1371/journal.pgen.1010485)
- Norris, K. et al. 2021. High-throughput STELA provides a rapid test for the diagnosis of telomere biology disorders. Human Genetics 140, pp. 945-955. (10.1007/s00439-021-02257-4)
- Liddiard, K., Grimstead, J., Cleal, K., Evans, A. and Baird, D. 2021. Tracking telomere fusions through crisis reveals conflict between DNA transcription and the DNA Damage Response. NAR Cancer 3(1), article number: zcaa044. (10.1093/narcan/zcaa044)
- Cleal, K. and Baird, D. 2020. Catastrophic endgames: emerging mechanisms of telomere-driven genomic instability. Trends in Genetics 36(5), pp. 347-359. (10.1016/j.tig.2020.02.001)
- Escudero, L., Cleal, K., Ashelford, K., Fegan, C., Pepper, C., Liddiard, K. and Baird, D. M. 2019. Telomere fusions associate with coding sequence and copy number alterations in CLL. Leukemia 33, pp. 2093-2097. (10.1038/s41375-019-0423-y)
- Cleal, K., Jones, R. E., Grimstead, J. W., Hendrickson, E. A. and Baird, D. M. 2019. Chromothripsis during telomere crisis is independent of NHEJ, and consistent with a replicative origin. Genome Research 29(5), pp. 737-749. (10.1101/gr.240705.118)
- Liddiard, K., Ruis, B., Kan, Y., Cleal, K., Ashelford, K. E., Hendrickson, E. A. and Baird, D. M. 2019. DNA Ligase 1 is an essential mediator of sister chromatid telomere fusions in G2 cell cycle phase. Nucleic Acids Research 47(5), pp. 2402-2424. (10.1093/nar/gky1279)
- Cleal, K., Norris, K. and Baird, D. 2018. Telomere length dynamics and the evolution of cancer genome architecture. International Journal of Molecular Sciences 19(2), pp. 482-482. (10.3390/ijms19020482)
- Sayers, E. J., Cleal, K., Eissa, N. G., Watson, P. D. and Jones, A. T. 2014. Distal phenylalanine modification for enhancing cellular delivery of fluorophores, proteins and quantum dots by cell penetrating peptides. Journal of Controlled Release 195, pp. 55-62. (10.1016/j.jconrel.2014.07.055)
- Cleal, K., He, L., Watson, P. D. and Jones, A. T. 2013. Endocytosis, intracellular traffic and fate of cell penetrating peptide based conjugates and nanoparticles. Current Pharmaceutical Design 19(16), pp. 2878-2894. (10.2174/13816128113199990297)
Thesis