Dr Magdalena Czubala

2024

• Czubala, M. A. et al. 2024. Tissue-specific transcriptional programming of macrophages controls the microRNA transcriptome targeting multiple functional pathways. Journal of Biological Chemistry 300 (5) 107244. (10.1016/j.jbc.2024.107244)
• Gurney, M. et al. 2024. Lentiviral vector preparation for efficient gene and microRNA modulation of peritoneal cavity tissue-resident macrophages in vivo in mice. Journal of Visualized Experiments 204 e64926. (10.3791/64926)
• Krishnacoumar, B. et al., 2024. Caspase-8 promotes scramblase-mediated phosphatidylserine exposure and fusion of osteoclast precursors. Bone Research 12 (1) 40. (10.1038/s41413-024-00338-4)

2022

• Czubala, M. A. et al. 2022. 3R Blackboard: A platform for animal and organ sharing. Laboratory Animals 56 (3), pp.292-296. (10.1177/00236772211067456)
• Misheva, M. et al. 2022. Oxylipin metabolism is controlled by mitochondrial β-oxidation during bacterial inflammation. Nature Communications 13 (1) 139. (10.1038/s41467-021-27766-8)

2021

• Griffiths, J. S. et al. 2021. A human Dectin-2 deficiency associated with invasive aspergillosis. Journal of Infectious Diseases 224 (7), pp.1219-1224. (10.1093/infdis/jiab145)
• Maguire, E. et al. 2021. PIP2 depletion and altered endocytosis caused by expression of Alzheimer's disease-protective variant PLCγ2 R522. EMBO Journal 40 (17) e105603. (10.15252/embj.2020105603)
• Triantafilou, K. et al. 2021. Differential recognition of HIV-stimulated IL-1? and IL-18 secretion through NLR and NAIP signalling in monocyte-derived macrophages. PLoS Pathogens 17 (4) e1009417. (10.1371/journal.ppat.1009417)

2020

• Ipseiz, N. et al. 2020. Effective in vivo gene modification in mouse tissue-resident peritoneal macrophages by intraperitoneal delivery of lentiviral vectors. Molecular Therapy - Methods and Clinical Development 16 , pp.21-31. (10.1016/j.omtm.2019.10.004)
• Ipseiz, N. et al. 2020. Tissue‐resident macrophages actively suppress IL‐1beta release via a reactive prostanoid/IL‐10 pathway. EMBO Journal 39 (14) e103454. (10.15252/embj.2019103454)

2019

• Maarifi, G. et al., 2019. Langerin (CD207) represents a novel interferon-stimulated gene in Langerhans cells. Cellular and Molecular Immunology 17 , pp.547-549. (10.1038/s41423-019-0302-5)
• Shimauchi, T. et al. 2019. Dendritic cells promote the spread of human T-cell leukemia virus type 1 via bidirectional interactions with CD4+ T cells. Journal of Investigative Dermatology 139 (1), pp.157-166. (10.1016/j.jid.2018.06.188)

2016

• Czubala, M. A. et al. 2016. TGFβ induces a SAMHD1-independent post-entry restriction to HIV-1 infection of human epithelial Langerhans cells. Journal of Investigative Dermatology 136 (10), pp.1981-1989. (10.1016/j.jid.2016.05.123)

2015

• Czubala, M. A. 2015. Transforming growth factor-beta (TGF-β) induces HIV-1 restriction in Langerhans cells. PhD Thesis , Cardiff University.

2013

• Blanchet, F. et al. 2013. TLR-4 engagement of dendritic cells confers a BST-2/tetherin-mediated restriction of HIV-1 infection to CD4+ T cells across the virological synapse. Retrovirology 10 6. (10.1186/1742-4690-10-6)