Dr Sunil Dolwani
Professor of Gastroenterology - Screening, Prevention and Early Detection of Cancer
Publication
2024
- Price, D., Brain, K., Dolwani, S., Edwards, A., Hood, K. and Smits, S. 2024. Perceptions of the impact of comorbidity on the Bowel Cancer Screening Programme: qualitative study with bowel screening participants and staff. Health Expectations 27(4), article number: e14126. (10.1111/hex.14126)
- Meuser, E. et al. 2024. PIGA mutations and glycosylphosphatidylinositol anchor dysregulation in polyposis-associated duodenal tumorigenesis. Molecular Cancer Research 22(6), pp. 515–523. (10.1158/1541-7786.MCR-23-0810)
- Ali, O., Gupta, S., Brain, K., Lifford, K. J., Paranjothy, S. and Dolwani, S. 2024. Acceptability of alternative technologies compared with faecal immunochemical test and/or colonoscopy in colorectal cancer screening: A systematic review. Journal of Medical Screening 30(1), pp. 14-27. (10.1177/09691413221109999)
- Elwood, P. et al. 2024. Aspirin and cancer treatment: systematic reviews and meta-analyses of evidence: for and against. British Journal of Cancer 130, pp. 3-8. (10.1038/s41416-023-02506-5)
2023
- Bresalier, R. S. et al. 2023. An efficient strategy for evaluating new non-invasive screening tests for colorectal cancer: the guiding principles. Gut 72(10), pp. 1904-1918. (10.1136/gutjnl-2023-329701)
- Clark, S. et al. 2023. Hereditary gastrointestinal polyposis syndromes Rare Disease Collaborative Network consensus statement agreed at the RDCN meeting Birmingham 17th February 2022. BJC Reports 1(1), article number: 10. (10.1038/s44276-023-00011-z)
- Parker, J., Gupta, S., Torkington, J. and Dolwani, S. 2023. Comparison of recommendations for surveillance of advanced colorectal polyps: a systematic review of guidelines. Journal of Gastroenterology and Hepatology 38(6), pp. 854-864. (10.1111/jgh.16157)
- Parker, J., Semedo, L., Shenbagaraj, L., Torkington, J. and Dolwani, S. 2023. Planning management for complex colorectal polyps: a qualitative assessment of factors influencing decision-making among colonoscopists. BMJ Open Gastroenterology 10, article number: e0010. (10.1136/bmjgast-2022-001097)
- Parker, J. et al. 2023. Outcomes of complex colorectal polyps managed by multi-disciplinary team strategies - a multi-centre observational study. International Journal of Colorectal Disease 38, article number: 28.
- Parker, J. et al. 2023. Outcomes of complex colorectal polyps managed by multi-disciplinary team strategies—a multi-centre observational study. International Journal of Colorectal Disease 38(1), article number: 28. (10.1007/s00384-022-04299-0)
2022
- Semedo, L., Gjini, A., Dolwani, S. and Lifford, K. J. 2022. Participants' experiences of the management of screen-detected complex polyps within a structured bowel cancer screening programme. Health Expectations 25(5), pp. 2355-2364. (10.1111/hex.13525)
- Kader, R. et al. 2022. Survey on the perceptions of UK gastroenterologists and endoscopists to artificial intelligence. Frontline Gastroenterology 13(5), pp. 423-429. (10.1136/flgastro-2021-101994)
2021
- Parker, J., Gupta, S., Torkington, J. and Dolwani, S. 2021. Multi-disciplinary decision-making strategies may reduce the need for secondary surgery in complex colonic polyps - a systematic review and pooled analysis. Colorectal Disease 23(12), pp. 3101-3112. (10.1111/codi.15901)
- Parker, J., Torkington, J., Davies, M. M. and Dolwani, S. 2021. Laparoscopically assisted endoscopic mucosal resection reduces the need for bowel resection for complex colonic polyps. British Journal of Surgery 108(5), pp. e196-e198. (10.1093/bjs/znab053)
- Semedo, L., Lifford, K. J., Edwards, A., Seddon, K., Brain, K., Smits, S. and Dolwani, S. 2021. Development and user-testing of a brief decision aid for aspirin as a preventive approach alongside colorectal cancer screening.. BMC Medical Informatics and Decision Making 21, article number: 165. (10.1186/s12911-021-01523-9)
- Thomas, L. E. et al. 2021. Duodenal adenomas and cancer in MUTYH-associated polyposis: an international cohort study. Gastroenterology 160(3), pp. 952-954. (10.1053/j.gastro.2020.10.038)
2020
- Sanyaolu, L. N., Oakley, N. J., Nurmatov, U., Dolwani, S. and Ahmed, H. 2020. Antibiotic exposure and the risk of colorectal adenoma and carcinoma: a systematic review and meta-analysis of observational studies. Colorectal Disease 22(8), pp. 858-870. (10.1111/codi.14921)
- Gupta, S., Parker, J., Smits, S., Underwood, J. and Dolwani, S. 2020. Persistent viral shedding of SARS‐CoV‐2 in faeces – a rapid review. Colorectal Disease 22(6), pp. 611-620. (10.1111/codi.15138)
2019
- Hurt, C. et al. 2019. Feasibility and economic assessment of chromocolonoscopy for detection of proximal serrated neoplasia within a population-based colorectal cancer screening programme (CONSCOP): an open-label, randomised controlled non-inferiority trial. Lancet Gastroenterology and Hepatology 4(5), pp. 364-375. (10.1016/S2468-1253(19)30035-4)
- East, J. E., Bhandari, P., Dolwani, S., MacCarthy, F., Rutter, M. D. and Saunders, B. P. 2019. Endoscopic excision of significant polyp and early colorectal cancer lesions. Colorectal Disease 21, pp. 37-40. (10.1111/codi.14493)
- Dolwani, S. 2019. Significant polyp and early colorectal cancer - decision-making and treatment planning in regional networks and multidisciplinary teams. Colorectal Disease 21(S1), pp. 16-18. (10.1111/codi.14492)
- Kopczynska, M. et al. 2019. Assessment of technical parameters and skills training to inform a simulation-based training program for semi-automated robotic colonoscopy. Endoscopy International Open 7(1), pp. E9-E14. (10.1055/a-0774-4554)
2018
- Elwood, P. et al. 2018. Systematic review update of observational studies further supports aspirin role in cancer treatment: Time to share evidence and decision-making with patients?. PLoS ONE 13(9), pp. e0203957. (10.1371/journal.pone.0203957)
- Hurley, J. J. et al. 2018. The impact of chromoendoscopy for surveillance of the duodenum in patients with MUTYH-associated polyposis and familial adenomatous polyposis. Gastrointestinal Endoscopy 88(4), pp. 665-673. (10.1016/j.gie.2018.04.2347)
- Stanciu, M. A. et al. 2018. Development of an intervention to expedite cancer diagnosis through primary care: a protocol. BJGP Open 2(3), article number: 18X101595. (10.3399/bjgpopen18X101595)
- Elwood, P. et al. 2018. Healthy living and cancer: evidence from UK Biobank. ecancermedicalscience 12, article number: 792. (10.3332/ecancer.2018.792)
2017
- Thomas, L. E. et al. 2017. Burden and profile of somatic mutation in duodenal adenomas from patients with familial adenomatous- and MUTYH-associated polyposis. Clinical Cancer Research 23(21), pp. 6721-6732. (10.1158/1078-0432.CCR-17-1269)
- Zhang, L., Dolwani, S. and Ye, X. 2017. Automated polyp segmentation in colonoscopy frames using fully convolutional neural network and textons. Presented at: Medical Image Understanding and Analysis 2017, Edinburgh, 11-13 July 2017 Presented at Valdés Hernández, M. and González-Castro, V. eds.Medical Image Understanding and Analysis, Vol. 723. Communications in Computer and Information Science Cham: Springer pp. 707-717., (10.1007/978-3-319-60964-5_62)
- East, J. E. et al. 2017. British Society of Gastroenterology position statement on serrated polyps in the colon and rectum. Gut 66(7), pp. 1181-1196. (10.1136/gutjnl-2017-314005)
- Monahan, K. J. et al. 2017. Urgent improvements needed to diagnose and manage Lynch syndrome. British Medical Journal 356, article number: j138. (10.1136/bmj.j138)
2016
- Elwood, P. C. et al. 2016. Systematic review and meta-analysis of randomised trials to ascertain fatal gastrointestinal bleeding events attributable to preventive low-dose aspirin: no evidence of increased risk. PLoS ONE 11(11), article number: e0166166. (10.1371/journal.pone.0166166)
- Yao, K. et al. 2016. Development of an E-learning system for the endoscopic diagnosis of early gastric cancer: An international multicentre randomized controlled trial. EBioMedicine 9, pp. 140-147. (10.1016/j.ebiom.2016.05.016)
- Elwood, P. C. et al. 2016. Aspirin in the treatment of cancer: reductions in metastatic spread and in mortality: a systematic review and meta-analyses of published studies. PLoS ONE 11(4), article number: e0152402. (10.1371/journal.pone.0152402)
2013
- Turner, J., Williams, G., Morgan, M., Wright, M. and Dolwani, S. 2013. Interobserver agreement in the reporting of colorectal polyp pathology among bowel cancer screening pathologists in Wales. Histopathology 62(6), pp. 916-924. (10.1111/his.12110)
- Turner, J. K., Wright, M., Morgan, M., Williams, G. T. and Dolwani, S. 2013. A prospective study of the accuracy and concordance between in-situ and postfixation measurements of colorectal polyp size and their potential impact upon surveillance. European Journal of Gastroenterology & Hepatology 25(5), pp. 562-567. (10.1097/MEG.0b013e32835d1f2d)
- Ansell, J. et al. 2013. The WIMAT colonoscopy suitcase model: a novel porcine polypectomy trainer. Colorectal Disease 15(2), pp. 217-223. (10.1111/j.1463-1318.2012.03122.x)
2008
- Dallosso, A. R. et al. 2008. Inherited predisposition to colorectal adenomas caused by multiple rare alleles of MUTYH but not OGG1, NUDT1, NTH1 or NEIL 1, 2 or 3. Gut 57(9), pp. 1252-1255. (10.1136/gut.2007.145748)
2007
- Dolwani, S. et al. 2007. Analysis of inherited MYH (MUTYH) mutations in British Asian patients with colorectal cancer [Letter]. Gut 56(4), pp. 593. (10.1136/gut.2006.094532)
2005
- Colley, J. et al. 2005. Rapid recognition of aberrant dHPLC elution profiles using the Transgenomic NavigatorTM software. Human Mutation 26(2), pp. 165. (10.1002/humu.9354)
- Sampson, J. R., Jones, S., Dolwani, S. and Cheadle, J. P. 2005. MutYH (MYH) and colorectal cancer. Biochemical Society Transactions 33(4), pp. 679-683. (10.1042/BST0330679)
2003
- Sampson, J. R. et al. 2003. Autosomal recessive colorectal adenomatous polyposis due to inherited mutations of MYH. The Lancet 362(9377), pp. 39-41. (10.1016/S0140-6736(03)13805-6)
- Cheadle, J. P., Dolwani, S. and Sampson, J. R. 2003. Inherited defects in the DNA glycosylase MYH cause multiple colorectal adenoma and carcinoma [Letter]. Carcinogenesis 24(7), pp. 1281-1282. (10.1093/carcin/bgg068)
Cynadleddau
- Zhang, L., Dolwani, S. and Ye, X. 2017. Automated polyp segmentation in colonoscopy frames using fully convolutional neural network and textons. Presented at: Medical Image Understanding and Analysis 2017, Edinburgh, 11-13 July 2017 Presented at Valdés Hernández, M. and González-Castro, V. eds.Medical Image Understanding and Analysis, Vol. 723. Communications in Computer and Information Science Cham: Springer pp. 707-717., (10.1007/978-3-319-60964-5_62)
Erthyglau
- Price, D., Brain, K., Dolwani, S., Edwards, A., Hood, K. and Smits, S. 2024. Perceptions of the impact of comorbidity on the Bowel Cancer Screening Programme: qualitative study with bowel screening participants and staff. Health Expectations 27(4), article number: e14126. (10.1111/hex.14126)
- Meuser, E. et al. 2024. PIGA mutations and glycosylphosphatidylinositol anchor dysregulation in polyposis-associated duodenal tumorigenesis. Molecular Cancer Research 22(6), pp. 515–523. (10.1158/1541-7786.MCR-23-0810)
- Ali, O., Gupta, S., Brain, K., Lifford, K. J., Paranjothy, S. and Dolwani, S. 2024. Acceptability of alternative technologies compared with faecal immunochemical test and/or colonoscopy in colorectal cancer screening: A systematic review. Journal of Medical Screening 30(1), pp. 14-27. (10.1177/09691413221109999)
- Elwood, P. et al. 2024. Aspirin and cancer treatment: systematic reviews and meta-analyses of evidence: for and against. British Journal of Cancer 130, pp. 3-8. (10.1038/s41416-023-02506-5)
- Bresalier, R. S. et al. 2023. An efficient strategy for evaluating new non-invasive screening tests for colorectal cancer: the guiding principles. Gut 72(10), pp. 1904-1918. (10.1136/gutjnl-2023-329701)
- Clark, S. et al. 2023. Hereditary gastrointestinal polyposis syndromes Rare Disease Collaborative Network consensus statement agreed at the RDCN meeting Birmingham 17th February 2022. BJC Reports 1(1), article number: 10. (10.1038/s44276-023-00011-z)
- Parker, J., Gupta, S., Torkington, J. and Dolwani, S. 2023. Comparison of recommendations for surveillance of advanced colorectal polyps: a systematic review of guidelines. Journal of Gastroenterology and Hepatology 38(6), pp. 854-864. (10.1111/jgh.16157)
- Parker, J., Semedo, L., Shenbagaraj, L., Torkington, J. and Dolwani, S. 2023. Planning management for complex colorectal polyps: a qualitative assessment of factors influencing decision-making among colonoscopists. BMJ Open Gastroenterology 10, article number: e0010. (10.1136/bmjgast-2022-001097)
- Parker, J. et al. 2023. Outcomes of complex colorectal polyps managed by multi-disciplinary team strategies - a multi-centre observational study. International Journal of Colorectal Disease 38, article number: 28.
- Parker, J. et al. 2023. Outcomes of complex colorectal polyps managed by multi-disciplinary team strategies—a multi-centre observational study. International Journal of Colorectal Disease 38(1), article number: 28. (10.1007/s00384-022-04299-0)
- Semedo, L., Gjini, A., Dolwani, S. and Lifford, K. J. 2022. Participants' experiences of the management of screen-detected complex polyps within a structured bowel cancer screening programme. Health Expectations 25(5), pp. 2355-2364. (10.1111/hex.13525)
- Kader, R. et al. 2022. Survey on the perceptions of UK gastroenterologists and endoscopists to artificial intelligence. Frontline Gastroenterology 13(5), pp. 423-429. (10.1136/flgastro-2021-101994)
- Parker, J., Gupta, S., Torkington, J. and Dolwani, S. 2021. Multi-disciplinary decision-making strategies may reduce the need for secondary surgery in complex colonic polyps - a systematic review and pooled analysis. Colorectal Disease 23(12), pp. 3101-3112. (10.1111/codi.15901)
- Parker, J., Torkington, J., Davies, M. M. and Dolwani, S. 2021. Laparoscopically assisted endoscopic mucosal resection reduces the need for bowel resection for complex colonic polyps. British Journal of Surgery 108(5), pp. e196-e198. (10.1093/bjs/znab053)
- Semedo, L., Lifford, K. J., Edwards, A., Seddon, K., Brain, K., Smits, S. and Dolwani, S. 2021. Development and user-testing of a brief decision aid for aspirin as a preventive approach alongside colorectal cancer screening.. BMC Medical Informatics and Decision Making 21, article number: 165. (10.1186/s12911-021-01523-9)
- Thomas, L. E. et al. 2021. Duodenal adenomas and cancer in MUTYH-associated polyposis: an international cohort study. Gastroenterology 160(3), pp. 952-954. (10.1053/j.gastro.2020.10.038)
- Sanyaolu, L. N., Oakley, N. J., Nurmatov, U., Dolwani, S. and Ahmed, H. 2020. Antibiotic exposure and the risk of colorectal adenoma and carcinoma: a systematic review and meta-analysis of observational studies. Colorectal Disease 22(8), pp. 858-870. (10.1111/codi.14921)
- Gupta, S., Parker, J., Smits, S., Underwood, J. and Dolwani, S. 2020. Persistent viral shedding of SARS‐CoV‐2 in faeces – a rapid review. Colorectal Disease 22(6), pp. 611-620. (10.1111/codi.15138)
- Hurt, C. et al. 2019. Feasibility and economic assessment of chromocolonoscopy for detection of proximal serrated neoplasia within a population-based colorectal cancer screening programme (CONSCOP): an open-label, randomised controlled non-inferiority trial. Lancet Gastroenterology and Hepatology 4(5), pp. 364-375. (10.1016/S2468-1253(19)30035-4)
- East, J. E., Bhandari, P., Dolwani, S., MacCarthy, F., Rutter, M. D. and Saunders, B. P. 2019. Endoscopic excision of significant polyp and early colorectal cancer lesions. Colorectal Disease 21, pp. 37-40. (10.1111/codi.14493)
- Dolwani, S. 2019. Significant polyp and early colorectal cancer - decision-making and treatment planning in regional networks and multidisciplinary teams. Colorectal Disease 21(S1), pp. 16-18. (10.1111/codi.14492)
- Kopczynska, M. et al. 2019. Assessment of technical parameters and skills training to inform a simulation-based training program for semi-automated robotic colonoscopy. Endoscopy International Open 7(1), pp. E9-E14. (10.1055/a-0774-4554)
- Elwood, P. et al. 2018. Systematic review update of observational studies further supports aspirin role in cancer treatment: Time to share evidence and decision-making with patients?. PLoS ONE 13(9), pp. e0203957. (10.1371/journal.pone.0203957)
- Hurley, J. J. et al. 2018. The impact of chromoendoscopy for surveillance of the duodenum in patients with MUTYH-associated polyposis and familial adenomatous polyposis. Gastrointestinal Endoscopy 88(4), pp. 665-673. (10.1016/j.gie.2018.04.2347)
- Stanciu, M. A. et al. 2018. Development of an intervention to expedite cancer diagnosis through primary care: a protocol. BJGP Open 2(3), article number: 18X101595. (10.3399/bjgpopen18X101595)
- Elwood, P. et al. 2018. Healthy living and cancer: evidence from UK Biobank. ecancermedicalscience 12, article number: 792. (10.3332/ecancer.2018.792)
- Thomas, L. E. et al. 2017. Burden and profile of somatic mutation in duodenal adenomas from patients with familial adenomatous- and MUTYH-associated polyposis. Clinical Cancer Research 23(21), pp. 6721-6732. (10.1158/1078-0432.CCR-17-1269)
- East, J. E. et al. 2017. British Society of Gastroenterology position statement on serrated polyps in the colon and rectum. Gut 66(7), pp. 1181-1196. (10.1136/gutjnl-2017-314005)
- Monahan, K. J. et al. 2017. Urgent improvements needed to diagnose and manage Lynch syndrome. British Medical Journal 356, article number: j138. (10.1136/bmj.j138)
- Elwood, P. C. et al. 2016. Systematic review and meta-analysis of randomised trials to ascertain fatal gastrointestinal bleeding events attributable to preventive low-dose aspirin: no evidence of increased risk. PLoS ONE 11(11), article number: e0166166. (10.1371/journal.pone.0166166)
- Yao, K. et al. 2016. Development of an E-learning system for the endoscopic diagnosis of early gastric cancer: An international multicentre randomized controlled trial. EBioMedicine 9, pp. 140-147. (10.1016/j.ebiom.2016.05.016)
- Elwood, P. C. et al. 2016. Aspirin in the treatment of cancer: reductions in metastatic spread and in mortality: a systematic review and meta-analyses of published studies. PLoS ONE 11(4), article number: e0152402. (10.1371/journal.pone.0152402)
- Turner, J., Williams, G., Morgan, M., Wright, M. and Dolwani, S. 2013. Interobserver agreement in the reporting of colorectal polyp pathology among bowel cancer screening pathologists in Wales. Histopathology 62(6), pp. 916-924. (10.1111/his.12110)
- Turner, J. K., Wright, M., Morgan, M., Williams, G. T. and Dolwani, S. 2013. A prospective study of the accuracy and concordance between in-situ and postfixation measurements of colorectal polyp size and their potential impact upon surveillance. European Journal of Gastroenterology & Hepatology 25(5), pp. 562-567. (10.1097/MEG.0b013e32835d1f2d)
- Ansell, J. et al. 2013. The WIMAT colonoscopy suitcase model: a novel porcine polypectomy trainer. Colorectal Disease 15(2), pp. 217-223. (10.1111/j.1463-1318.2012.03122.x)
- Dallosso, A. R. et al. 2008. Inherited predisposition to colorectal adenomas caused by multiple rare alleles of MUTYH but not OGG1, NUDT1, NTH1 or NEIL 1, 2 or 3. Gut 57(9), pp. 1252-1255. (10.1136/gut.2007.145748)
- Dolwani, S. et al. 2007. Analysis of inherited MYH (MUTYH) mutations in British Asian patients with colorectal cancer [Letter]. Gut 56(4), pp. 593. (10.1136/gut.2006.094532)
- Colley, J. et al. 2005. Rapid recognition of aberrant dHPLC elution profiles using the Transgenomic NavigatorTM software. Human Mutation 26(2), pp. 165. (10.1002/humu.9354)
- Sampson, J. R., Jones, S., Dolwani, S. and Cheadle, J. P. 2005. MutYH (MYH) and colorectal cancer. Biochemical Society Transactions 33(4), pp. 679-683. (10.1042/BST0330679)
- Sampson, J. R. et al. 2003. Autosomal recessive colorectal adenomatous polyposis due to inherited mutations of MYH. The Lancet 362(9377), pp. 39-41. (10.1016/S0140-6736(03)13805-6)
- Cheadle, J. P., Dolwani, S. and Sampson, J. R. 2003. Inherited defects in the DNA glycosylase MYH cause multiple colorectal adenoma and carcinoma [Letter]. Carcinogenesis 24(7), pp. 1281-1282. (10.1093/carcin/bgg068)
Contact Details
DolwaniS@cardiff.ac.uk
+44 29206 87336
Neuadd Meirionnydd, Room 6th Floor, University Hospital of Wales, Heath Park, Cardiff, CF14 4YS
+44 29206 87336
Neuadd Meirionnydd, Room 6th Floor, University Hospital of Wales, Heath Park, Cardiff, CF14 4YS