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Luciana Gonzaga De Oliveira   BA MSc PhD

Professor Luciana Gonzaga De Oliveira

(she/they)

BA MSc PhD

Postdoctoral Research Associate (with Prof Rudolf Allemann)

School of Chemistry

Email
GonzagaDeOliveiraL@cardiff.ac.uk
Campuses
Main Building, Room 1.112, Park Place, Cardiff, CF10 3AT

Overview

In Brazil, at UNICAMP I’ve pioneered genome to molecules and enzymes application by using genome-mining strategies Genome to molecules approaches represents an encouraging avenue to elect and isolate new bioactive targets. We've combined genome sequencing and annotation with modern synthetic biology approaches, in vivo and in vitro recombination to access known and unknown metabolites in the scope of gaining improved knowledge of our biodiversity to develop sustainable livelihoods and bioeconomy. By sequencing actinobacteria endophytic and from soil we were able to elect several gene clusters and enzymes of biotechnological interest and decipher unique structures and biosynthetic pathways involved in the biosynthesis of cyclodepsipeptides and hybrid PKS-NRPS encoded compounds by using MS-Guided Genome Mining.

Publication

2022

2021

2020

2019

2018

2016

2015

2014

2013

2010

2009

2008

2007

2006

2005

2004

2003

2001

Erthyglau

Biography

Current and Previous Positions

2022-                Research Associate, School of Chemistry, Cardiff University

2020-2022        Associate Professor, Department of Organic Chemistry, Institute of Chemistry, UNICAMP (Full-time)

2012-2013        Academic Visitor, University of Cambridge, Department of Biochemistry

                         Advisor: Prof Peter F. Leadlay, Fellowship: FAPESP (BR), Focus on Biosynthesis and Enzymology

June 2010         Promoted to Assistant Professor MS3-II, Department of Organic Chemistry, Institute of Chemistry, UNICAMP (Full-time)

June/2008         Assistant Professor MS3-I, Department of Organic Chemistry, Institute of Chemistry, UNICAMP (Full-time)

2007-2007         Postdoctoral Fellow, Max Planck Institut für Kohlenforschung

                          Advisor: Prof. Manfred T. Reetz, Focus on Molecular Biology and Directed Evolution

2005-2008         Postdoctoral Fellow, Department of Organic Chemistry, Institute of Chemistry, UNICAMP, Brazil

                          Advisor: Prof. Anita Jocelyne Marsaioli, Focus on Biocatalysis using Whole Cells Micoorganisms

2000-2004        PhD in Chemistry, University of Campinas, Brazil

                         Thesis Title: “Total Synthesis of (+)-Crocacins C and D; Synthesis of the 6,6-Spiroketal Core of Spirofungins A and B”

1998-2000        Master’s Degree in Chemistry, University of Campinas, Brazil 

                         Dissertation Title: Towards the Total Synthesis of the Immunosuppressant Agent Pironetin

1994-1997        Undergraduate in Chemistry, University of Campinas, Brazil

Honours and awards

Fellowships, prizes and awards

2020 – Member of the For Women in Science Community Network – Alumni

2020 – Top Downloaded Article – ChemistrySelect – New Cyclodepsipeptides Derivatives Revealed by Genome Mining and Molecular Networking – Wiley  

Jan-Feb 2020 – Academic Visitor – Cardiff University – Prof. Rudolf Allemann – Fellowship: Cardiff Mobility Grant

2019 – Cover Picture ChemistrySelect – New Cyclodepsipeptides Derivatives Revealed by Genome Mining and Molecular Networking

2019 – Cover Picture Química Nova – Recent Advances in Combinatorial Biosynthesis of Polyketides: Perspectives and Challenges

2019 – Selected Manuscript to the JBCS Special Issue – Brazilian Researchers Abroad

2018 – Member of the Lindau Alumni Network

2018 – Selected Manuscript to the JBCS and RSC cross-journal collection to celebrate the UK-BR Year of Science and Innovation.

2015 – Participant of the HUMBOLDT COLLOQUIUM – Research Excellence in a Globalized World: Experiences and Challenges from a Brazilian-German Perspective, Alexander von Humboldt Foundation – nominated by the Max Planck Gesellschaft

2014 – Inside Cover ChemBioChem - A European Journal of Chemical Biology: Site-Specific Modification of the Anticancer and Antituberculosis Polyether Salinomycin by Biosynthetic Engineering

2014 – Scientific Merit, PRP/UNICAMP – XXII Undergraduate Scientific Congress - UNICAMP

2014 – Certificate of Commendation - 2nd Meeting of the Brazilian Proteomics Society, Brazilian Proteomics Society

Feb 2012- Feb 2013 – Academic Visitor / Post-Doctorate – University of Cambridge – Department of Biochemistry – Prof Peter F. Leadlay – Fellowiship: FAPESP (BR)

2009 - Participant of the "59th Meeting of Nobel Laureates (19th Meeting dedicated to Chemistry)" – Nominated by Lindau Council/Brazilian Academy of Science

2008 – Grant “For Women in Science” L’Oreal/ABC/Unesco, Brazilian Edition, Chemical Sciences

Jan-May 2007 – Post-Doctorate – Max-Planck-Institut für Kohlenforschung – Prof. Manfred T. Reetz – Fellowship: FAPESP (BR)

2005-2008 - Postdoctoral Fellow, Department of Organic Chemistry, Institute of Chemistry, UNICAMP, Brazil – Prof. Anita Jocelyne Marsaioli – Fellowship: FAPESP (BR)

Professional memberships

Member of the For Women in Science Community Network – Alumni

Member of the Lindau Alumni Network

Member of the LatinXChem.org initiative

Member of The Brazilian Chemical Society since 1995

Member of The American Society of Pharmacognosy

Research themes

Specialisms

  • Biocatalysis and enzyme technology
  • Natural products and bioactive compounds
  • Metabolomic chemistry
  • Genomics