![Luke Johnson](https://profiles-cardiff.imgix.net/attachments/1493?w=200&h=200&auto=format&crop=faces&fit=crop&q=90")
Overview
Luke is a Postdoctoral Research Associate with Prof. Rudolf Allemann with an interest in developing new biocatalysis methods for applications in production of pheromones and other semiochemicals for invasive insect pests control and agriculture crop protection.
Publication
2024
- Johnson, L. A. and Allemann, R. K. 2024. Engineering terpene synthases and their substrates for the biocatalytic production of terpene natural products and analogues. Chemical Communications (10.1039/D4CC05785F)
- Srivastava, P. L., Johnson, L. A., Miller, D. J. and Allemann, R. K. 2024. Production of non-natural terpenoids through chemoenzymatic synthesis using substrate analogs. In: Methods in Enzymology. Elsevier, (10.1016/bs.mie.2024.03.015)
- Johnson, L. A., Mart, R. J. and Allemann, R. K. 2024. A photoresponsive homing endonuclease for programmed DNA cleavage. ACS Synthetic Biology 13(1), pp. 195-205. (10.1021/acssynbio.3c00425)
2020
- Johnson, L. A., Dunbabin, A., Benton, J. C. R., Mart, R. J. and Allemann, R. K. 2020. Modular chemoenzymatic synthesis of terpenes and their analogues. Angewandte Chemie International Edition 59(22), pp. 8486-8490. (10.1002/anie.202001744)
2019
- Kalvaitis, M. E., Johnson, L. A., Mart, R. J., Rizkallah, P. and Allemann, R. K. 2019. A noncanonical chromophore reveals structural rearrangements of the light-oxygen-voltage domain upon photoactivation. Biochemistry 58(22), pp. 2608-2616. (10.1021/acs.biochem.9b00255)
2018
- Johnson, L. A. et al. 2018. van der Waals contact between nucleophile and transferring phosphorus is insufficient to achieve enzyme transition-state architecture. ACS Catalysis 8(9), pp. 8140-8153. (10.1021/acscatal.8b01612)
2017
- Hughes, R. L., Johnson, L. A., Behiry, E. M., Loveridge, E. J. and Allemann, R. K. 2017. A rapid analysis of variations in conformational behavior during dihydrofolate reductase catalysis. Biochemistry 56(15), pp. 2126-2133. (10.1021/acs.biochem.7b00045)
Articles
- Johnson, L. A. and Allemann, R. K. 2024. Engineering terpene synthases and their substrates for the biocatalytic production of terpene natural products and analogues. Chemical Communications (10.1039/D4CC05785F)
- Johnson, L. A., Mart, R. J. and Allemann, R. K. 2024. A photoresponsive homing endonuclease for programmed DNA cleavage. ACS Synthetic Biology 13(1), pp. 195-205. (10.1021/acssynbio.3c00425)
- Johnson, L. A., Dunbabin, A., Benton, J. C. R., Mart, R. J. and Allemann, R. K. 2020. Modular chemoenzymatic synthesis of terpenes and their analogues. Angewandte Chemie International Edition 59(22), pp. 8486-8490. (10.1002/anie.202001744)
- Kalvaitis, M. E., Johnson, L. A., Mart, R. J., Rizkallah, P. and Allemann, R. K. 2019. A noncanonical chromophore reveals structural rearrangements of the light-oxygen-voltage domain upon photoactivation. Biochemistry 58(22), pp. 2608-2616. (10.1021/acs.biochem.9b00255)
- Johnson, L. A. et al. 2018. van der Waals contact between nucleophile and transferring phosphorus is insufficient to achieve enzyme transition-state architecture. ACS Catalysis 8(9), pp. 8140-8153. (10.1021/acscatal.8b01612)
- Hughes, R. L., Johnson, L. A., Behiry, E. M., Loveridge, E. J. and Allemann, R. K. 2017. A rapid analysis of variations in conformational behavior during dihydrofolate reductase catalysis. Biochemistry 56(15), pp. 2126-2133. (10.1021/acs.biochem.7b00045)
Book sections
- Srivastava, P. L., Johnson, L. A., Miller, D. J. and Allemann, R. K. 2024. Production of non-natural terpenoids through chemoenzymatic synthesis using substrate analogs. In: Methods in Enzymology. Elsevier, (10.1016/bs.mie.2024.03.015)
Contact Details
Research themes
Specialisms
- Pheromones and other Semiochemicals
- Terpene chemistry
- Natural products and bioactive compounds
- Biochemistry
- Biocatalysis and enzyme technology
