![Luke Johnson](https://profiles-cardiff.imgix.net/attachments/1493?w=200&h=200&auto=format&crop=faces&fit=crop&q=90")
Overview
Luke is a Postdoctoral Research Associate with Prof. Rudolf Allemann with an interest in developing new biocatalysis methods for applications in production of pheromones and other semiochemicals for invasive insect pests control and agriculture crop protection.
Publication
2025
- Johnson, L. A. and Allemann, R. K. 2025. Engineering terpene synthases and their substrates for the biocatalytic production of terpene natural products and analogues. Chemical Communications 61 (12), pp.2468-2483. (10.1039/D4CC05785F)
2024
- Johnson, L. A. , Mart, R. J. and Allemann, R. K. 2024. A photoresponsive homing endonuclease for programmed DNA cleavage. ACS Synthetic Biology 13 (1), pp.195-205. (10.1021/acssynbio.3c00425)
- Srivastava, P. L. et al. 2024. Production of non-natural terpenoids through chemoenzymatic synthesis using substrate analogs. In: Rudolf, J. ed. Methods in Enzymology. Elsevier. , pp.207-230. (10.1016/bs.mie.2024.03.015)
2020
- Johnson, L. A. et al. 2020. Modular chemoenzymatic synthesis of terpenes and their analogues. Angewandte Chemie International Edition 59 (22), pp.8486-8490. (10.1002/anie.202001744)
2019
- Kalvaitis, M. E. et al. 2019. A noncanonical chromophore reveals structural rearrangements of the light-oxygen-voltage domain upon photoactivation. Biochemistry 58 (22), pp.2608-2616. (10.1021/acs.biochem.9b00255)
2018
- Johnson, L. A. et al. 2018. van der Waals contact between nucleophile and transferring phosphorus is insufficient to achieve enzyme transition-state architecture. ACS Catalysis 8 (9), pp.8140-8153. (10.1021/acscatal.8b01612)
2017
- Hughes, R. L. et al. 2017. A rapid analysis of variations in conformational behavior during dihydrofolate reductase catalysis. Biochemistry 56 (15), pp.2126-2133. (10.1021/acs.biochem.7b00045)
Articles
- Hughes, R. L. et al. 2017. A rapid analysis of variations in conformational behavior during dihydrofolate reductase catalysis. Biochemistry 56 (15), pp.2126-2133. (10.1021/acs.biochem.7b00045)
- Johnson, L. A. et al. 2020. Modular chemoenzymatic synthesis of terpenes and their analogues. Angewandte Chemie International Edition 59 (22), pp.8486-8490. (10.1002/anie.202001744)
- Johnson, L. A. , Mart, R. J. and Allemann, R. K. 2024. A photoresponsive homing endonuclease for programmed DNA cleavage. ACS Synthetic Biology 13 (1), pp.195-205. (10.1021/acssynbio.3c00425)
- Johnson, L. A. et al. 2018. van der Waals contact between nucleophile and transferring phosphorus is insufficient to achieve enzyme transition-state architecture. ACS Catalysis 8 (9), pp.8140-8153. (10.1021/acscatal.8b01612)
- Johnson, L. A. and Allemann, R. K. 2025. Engineering terpene synthases and their substrates for the biocatalytic production of terpene natural products and analogues. Chemical Communications 61 (12), pp.2468-2483. (10.1039/D4CC05785F)
- Kalvaitis, M. E. et al. 2019. A noncanonical chromophore reveals structural rearrangements of the light-oxygen-voltage domain upon photoactivation. Biochemistry 58 (22), pp.2608-2616. (10.1021/acs.biochem.9b00255)
Book sections
- Srivastava, P. L. et al. 2024. Production of non-natural terpenoids through chemoenzymatic synthesis using substrate analogs. In: Rudolf, J. ed. Methods in Enzymology. Elsevier. , pp.207-230. (10.1016/bs.mie.2024.03.015)
Contact Details
Research themes
Specialisms
- Pheromones and other Semiochemicals
- Terpene chemistry
- Natural products and bioactive compounds
- Biochemistry
- Biocatalysis and enzyme technology
