![Angharad Jones](https://profiles-cardiff.imgix.net/attachments/1075?w=200&h=200&auto=format&crop=faces&fit=crop&q=90")
Dr Angharad Jones
Lecturer
- Available for postgraduate supervision
Overview
Research overview
My research is related to the role and regulation of cellular processes such as growth and division during plant development. I am interested in how these processes are co-ordinated across many cells to produce patterns and structures that are visible at higher levels of organisation. These relationships are central to the way that environmental stresses impact plant growth and crop yields.
Publication
2023
- Williamson, D., Tasker-Brown, W., Murray, J. A. H., Jones, A. and Band, L. R. 2023. Modelling how plant cell-cycle progression leads to cell size regulation. PLoS Computational Biology (10.1371/journal.pcbi.1011503)
2020
- Rojas, O., Forero, M. G., Menendez, J. M., Jones, A., Dewitte, W. and Murray, J. A. H. 2020. Segmentation of meristem cells by an automated opinion algorithm. Journal of Applied Sciences 10(23), article number: 8523. (10.39390/app10238523)
2019
- Jones, A. R., Band, L. R. and Murray, J. A. H. 2019. Double or nothing? Cell division and cell size control. Trends in Plant Science 24(12), pp. 1083-1093. (10.1016/j.tplants.2019.09.005)
- Jones, A. and Dewitte, W. 2019. Cell size and cell cycle progression: the cyclin-dependent kinase link in green algae. Journal of Experimental Botany 70(3), pp. 731-377. (10.1093/jxb/erz008)
2018
- Grones, P., Abas, M., Hajný, J., Jones, A., Waidmann, S., Kleine-Vehn, J. and Friml, J. 2018. PID/WAG-mediated phosphorylation of the Arabidopsis PIN3 auxin transporter mediates polarity switches during gravitropism. Scientific Reports 8, article number: 10279. (10.1038/s41598-018-28188-1)
- Scofield, S. et al. 2018. Coordination of meristem and boundary functions by transcription factors in the SHOOT MERISTEMLESS regulatory network. Development 145(9), article number: dev157081. (10.1242/dev.157081)
2017
- Jones, A. R., Forero-Vargas, M., Withers, S. P., Smith, R. S., Traas, J., Dewitte, W. and Murray, J. A. H. 2017. Cell-size dependent progression of the cell cycle creates homeostasis and flexibility of plant cell size. Nature Communications 8, article number: 15060. (10.1038/ncomms15060)
2014
- Scofield, S., Jones, A. and Murray, J. A. H. 2014. The plant cell cycle in context. Journal of Experimental Botany 65(10), pp. 2557-2562. (10.1093/jxb/eru188)
2012
- Murray, J. A. H., Jones, A. R., Godin, C. and Traas, J. 2012. Systems analysis of shoot apical meristem growth and development: integrating hormonal and mechanical signaling. The Plant Cell 24(10), pp. 3907-3919. (10.1105/tpc.112.102194)
2010
- Kleine-Vehn, J., Ding, Z., Jones, A., Tasaka, M., Morita, M. T. and Friml, J. 2010. Gravity-induced PIN transcytosis for polarization of auxin fluxes in gravity-sensing root cells. Proceedings of the National Academy of Sciences of the United States of America 107(51), pp. 22344-22349. (10.1073/pnas.1013145107)
- Friml, J. and Jones, A. R. 2010. Endoplasmic reticulum: the rising compartment in auxin biology. Plant Physiology 154(2), pp. 458-462. (10.1104/pp.110.161380)
2009
- Jones, A. R. et al. 2009. Auxin transport through non-hair cells sustains root-hair development [Letter]. Nature Cell Biology 11(1), pp. 78-84. (10.1038/ncb1815)
Articles
- Williamson, D., Tasker-Brown, W., Murray, J. A. H., Jones, A. and Band, L. R. 2023. Modelling how plant cell-cycle progression leads to cell size regulation. PLoS Computational Biology (10.1371/journal.pcbi.1011503)
- Rojas, O., Forero, M. G., Menendez, J. M., Jones, A., Dewitte, W. and Murray, J. A. H. 2020. Segmentation of meristem cells by an automated opinion algorithm. Journal of Applied Sciences 10(23), article number: 8523. (10.39390/app10238523)
- Jones, A. R., Band, L. R. and Murray, J. A. H. 2019. Double or nothing? Cell division and cell size control. Trends in Plant Science 24(12), pp. 1083-1093. (10.1016/j.tplants.2019.09.005)
- Jones, A. and Dewitte, W. 2019. Cell size and cell cycle progression: the cyclin-dependent kinase link in green algae. Journal of Experimental Botany 70(3), pp. 731-377. (10.1093/jxb/erz008)
- Grones, P., Abas, M., Hajný, J., Jones, A., Waidmann, S., Kleine-Vehn, J. and Friml, J. 2018. PID/WAG-mediated phosphorylation of the Arabidopsis PIN3 auxin transporter mediates polarity switches during gravitropism. Scientific Reports 8, article number: 10279. (10.1038/s41598-018-28188-1)
- Scofield, S. et al. 2018. Coordination of meristem and boundary functions by transcription factors in the SHOOT MERISTEMLESS regulatory network. Development 145(9), article number: dev157081. (10.1242/dev.157081)
- Jones, A. R., Forero-Vargas, M., Withers, S. P., Smith, R. S., Traas, J., Dewitte, W. and Murray, J. A. H. 2017. Cell-size dependent progression of the cell cycle creates homeostasis and flexibility of plant cell size. Nature Communications 8, article number: 15060. (10.1038/ncomms15060)
- Scofield, S., Jones, A. and Murray, J. A. H. 2014. The plant cell cycle in context. Journal of Experimental Botany 65(10), pp. 2557-2562. (10.1093/jxb/eru188)
- Murray, J. A. H., Jones, A. R., Godin, C. and Traas, J. 2012. Systems analysis of shoot apical meristem growth and development: integrating hormonal and mechanical signaling. The Plant Cell 24(10), pp. 3907-3919. (10.1105/tpc.112.102194)
- Kleine-Vehn, J., Ding, Z., Jones, A., Tasaka, M., Morita, M. T. and Friml, J. 2010. Gravity-induced PIN transcytosis for polarization of auxin fluxes in gravity-sensing root cells. Proceedings of the National Academy of Sciences of the United States of America 107(51), pp. 22344-22349. (10.1073/pnas.1013145107)
- Friml, J. and Jones, A. R. 2010. Endoplasmic reticulum: the rising compartment in auxin biology. Plant Physiology 154(2), pp. 458-462. (10.1104/pp.110.161380)
- Jones, A. R. et al. 2009. Auxin transport through non-hair cells sustains root-hair development [Letter]. Nature Cell Biology 11(1), pp. 78-84. (10.1038/ncb1815)
Research
Cell Growth and Division in the Shoot Apical Meristem
My group uses a systems biology approach that combines timelapse imaging of individual cells within living tissues, mathematical modelling and molecular biology to understand cell growth and division as a dynamic problem. This is particularly important in plants, which have to adapt their growth to suit their environment.
I am interested in how growth and division of individual cells determines the overall architecture of the plant, and how these relationships are impacted by environmental stresses. Understanding these cellular rules and if and how they can be broken will allow us to produce plants that can better tolerate extreme and changeable environmental conditions.
Biography
I graduated in Biology from the University of York in 2004. During my undergraduate study I became interested in plant development and carried out a research project in the group of Prof. Ottoline Leyser on the regulation of shoot branching in snapdragon. I was then awarded a BBSRC PhD studentship at the University of Bristol to work under the supervision of Prof. Claire Grierson and Dr Colin Lazarus investigating the roles of auxin in the regulation of root-hair development. Following my PhD in 2009, I was awarded funding from the University of Bristol Lady Emily Smyth Agricultural Research Station to follow up work stemming from my PhD and also received a Royal Society Travel Grant to visit the lab of Prof. Jiřί Friml. I moved to Cardiff University in 2010 joining the group of Prof. Jim Murray. In 2019 I was appointed as a Disglair Lecturer.
Supervisions
I am interested in supervising students in the areas of:
- Stress responses in meristems
- Regulation of cell size during differentiation
- Co-ordinating cellular and whole organism growth
- Developing tools for tracking cell growth and cell division in intact tissues
I currently have a PhD projects available on stress responses in meristems. Please contact me for further information.
