Dr Lucy Jones

Publication

• Date
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Research

Current CI research projects include:

'IRFLUVA - Improving the long term immune response to the flu vaccine in older people' ( Dr Lucy Jones, Professor Katja Simon, Dr Ghada Alsaleh, Professor Paul Klenerman, Professor Teresa Lambe, Professor Andrew Sewell and Dr Brad Spiller) University of Oxford and Cardiff University. A randomised controlled, double blinded pilot study to determine the safety of daily nutritional supplements following vaccination for influenza - Portfolio study. 2023 - ongoing.

'COVID MEMORY' Study ( Dr Lucy Jones, Professor Katja Simon, Dr Ghada Alsaleh, Professor Paul Klenerman, Professor Teresa Lambe and Dr Brad Spiller) University of Oxford and Cardiff University. A randomised controlled, double blinded pilot study to determine the safety of daily nutritional supplements following vaccination for Coronavirus - 2022 and ongoing.

The CROWN Study – 'Characterisation of the Immune Response to SARS-CoV2 Infection'. (Dr Lucy Jones, Professor Andrew Sewell, Professor Paul Klenerman, Professor Mary Carrington, Dr Brad Spiller) 2020 – 2023. Cwm Taf Morgannwg, University of Oxford, Cardiff University and NIH (USA).

'Characterisation of the Immune Response to SARS-CoV2 Infection in Type 1 diabetes'. (Professor Andrew Sewell, Dr Lucy Jones, Professor John Geen, Professor Philip Goulder,  Dr Brad Spiller and Dr Karen Logan) Cwm Taf Morgannwg University health board, Cardiff University, University of Oxford and Imperial College - ongoing.

A Phase 2/3 RCT of reactogenicity of MODERNA COVID OMICRON booster vaccine
Principal Investigator for the All Wales Vaccine Research Taskforce and Public Health Wales (April 2022 – 2023).

The 'Antibiotic Guardian Study' (Dr Lucy Jones, Dr Brad Spiller and Dr Sarah Maddocks)  Cwm Taf Morgannwg, Cardiff University, Cardiff Metropolitan University research study (2019-2023).

'The STRAVINSKY Study' Stratification of Clinically Vulnerable People for COVID-19 Risk Using Antibody Testing (2023-ongoing). Principal Investigator - a portfolio study with University of Oxford, University of Birmingham, Cardiff University and University of Southampton.

Past studies:

SARS-CoV-2 Immunity of Family/Household Members (Dr Lucy Jones, Professor Paul Klenerman, Professor Philip Goulder) University of   Oxford. Characterisation of the differential immune responses to SARS-CoV-2 and COVID vaccines in people aged 8 years to 90 years.

The UROGEN WELL D-ONE Study (Dr Lucy Jones and Dr Brad Spiller).  Portfolio clinical research study with Cardiff University/Cwm Taf Morgannwg health board.

The MYCOWELL D-ONE Study (Dr Lucy Jones and Dr Brad Spiller) (2019). Portfolio clinical research study Cardiff University/Cwm Taf Morgannwg health board.

Do genitourinary Mycoplasma species cause disease? (Dr Lucy Jones and Ms Rebecca Davies)  Portfolio clinical research study Cwm Taf Morgannwg health board. 2019-2020

The role of Pax6 in the development of the forebrain (Dr Lucy Jones and Professor Zoltan Molnar)  Pre-clinical laboratory research study at University of Oxford.

Teaching

I teach undergraduate medical students and doctors in training in the field of HIV medicine and sexual health.

I supervise and teach undergraduate students completing a placement training year in Bioscience/Biomedical Sciences during their research modules in the field of infectious disease.

I supervise and teach medical students who decide to study for an intercalated degree in the field of infection and immunity.

Biography

I have a translational and experimental medicine research portfolio which focuses on improving our understanding of infections, vaccination and the corresponding immune response. I also have an interest in developing novel, rapid diagnostics for infection. This includes studies in Cardiff University, University of Oxford, Imperial College, Cardiff and the Vale University health board, Cwm Taf Morgannwg University health board and NIH.

I was born in Wales and raised in the Valleys of South Wales, before studying Medicine and Physiological Sciences at the University of Oxford. Following my medical qualification and training, I went on to complete a doctorate in the Department of Human Anatomy and Genetics, University of Oxford in the field of development and genetics with Dr Zoltan Molnar and Professor Colin Blakemore.

I have worked in Cwm Taf Morgannwg University health board for 19 years and I am an Associate Specialist and the departmental lead for research. I was made an Honorary lecturer at Cardiff University, School of Medicine in 2012 with a teaching role primarily and have now moved to a research focused role and work closely with a clinical research team at the Clinical Research Facility, Cardiff and the Vale University health board and collaborators at Cardiff University, University of Oxford, Imperial College, Cardiff Metropolitan University, University of Birmingham and NIH.

I also have an interest in working with industry to deliver research trials with benefits to patients in Wales and was Principal Investigator for the OMICRON vaccine trial in Wales in my role as an Honorary Associate Specialist with Public Health Wales. I co-supervise post-graduate students and play a role in teaching in the field of infection. I enjoy leading outreach activities in the field of infection and immunity.

Academic positions

Honorary Clinical Lecturer, Cardiff University, 2012-2023.

Supervisions

Infectious diease

Immunology

Microbiology

Clinical trials

Current supervision

Martin Sharratt

Research student

Engagement

I enjoy outreach activities relating to antimicrobial resistance (AMR) in bacterial infections. I have been involved in a large National outreach programme with The Ineos Oxford Institute (University of Oxford) which reaches out to the public to discuss the threat AMR poses to society, particularly in the field of sexual health. I also lead an outreach project for Cardiff University called 'BBV and Me', which aims to raise awareness of the blood borne viruses (BBV) called HIV, Hepatitis B and Hepatitis C. Our outreach acitivities discuss the aetiology and mode of transmission of BBV infections in a community setting with heterosexual people aged over 40 years of age. We discuss barriers to HIV testing with health care professionals. This is an important project implemented to support the All Wales HIV Action Plan and reduce late diagnosis of BBV. Activities are funded by an industrial partner.