Ryan Jones
Teams and roles for Ryan Jones
Research Associate, School of Biosciences
School of Biosciences
Overview
I am post-doctoral research associate within the Biomechanics and Bioengineering Centre Versus Arthritis in Cardiff University, where I investigate the interfce between neural and bony tissues and how these interactions can generate pain in pathology. My ambition is to become an established academic in the field of pain in musculoskeletal conditions, by delivering high impact research and developing new methods of modelling disease mechanisms.
I have contributed to the development of the mechanical 3D osteocyte bone model with a particular emphasis on bone interactions with the nerves upon mechanical loading and inflammation to reveal pain mechanisms. I have extensive research experience in musculoskeletal biology focussing on molecular mechanisms involved in mechanical and inflammatory responses elucidating new signalling mechanisms that regulate bone and nerve biology, to provide therapeutic and diagnostic targets for pain in musculoskeletal disease.
I have fortunate to recieve multiple awards for my research including; 'Highest rated abstract' at osteoarthritis research international annual meeting, Welsh Livery Company Gold award and Andrew Sprowson award for translational research at the British Orthopaedic Research Society annual meeting in 2023 and I have been awarded the British Orthopaedic Research Society/Bone and Joint Journal travelling fellowship in 2024.
Publication
2024
- Jones, R., Gilbert, S. J., Christofides, S. R. and Mason, D. J. 2024. Osteocytes contribute to sex-specific differences in osteoarthritic pain. Frontiers in Endocrinology 15, article number: 1480274. (10.3389/fendo.2024.1480274)
- Gilbert, S. J., Jones, R., Egan, B. J., Bonnet, C. S., Evans, S. L. and Mason, D. J. 2024. Investigating mechanical and inflammatory pathological mechanisms in osteoarthritis using MSC-derived osteocyte-like cells in 3D. Frontiers in Endocrinology 15, article number: 1359052. (10.3389/fendo.2024.1359052)
- Jones, R. 2024. Investigating the role of bone and nerve interactions in osteoarthritic pain and pathology. PhD Thesis, Cardiff University.
2023
- Hamilton, R. et al. 2023. Measuring osteoarthritis knee nociception using physiological and movement response and a defined thermal stimulus: A proof-of-concept study.. Presented at: The International Combined Orthopaedic Research Societies (ICORS), World Congress of Orthopaedic Research, Edinburgh, UK, 7-9 September 2022Orthopaedic Proceedings, Vol. 105-B,. pp. 20-20., (10.1302/1358-992X.2023.8.020)
2021
- Hamilton, R., Holt, C., Jones, R., Shillabeer, D., Sparkes, V. and Mason, D. 2021. Measuring nociception in knee osteoarthritis using physiological and movement responses: a proof-of-concept study. Presented at: British Orthopaedic Research Society, Cardiff, UK, 13-14 September 2021.
Articles
- Jones, R., Gilbert, S. J., Christofides, S. R. and Mason, D. J. 2024. Osteocytes contribute to sex-specific differences in osteoarthritic pain. Frontiers in Endocrinology 15, article number: 1480274. (10.3389/fendo.2024.1480274)
- Gilbert, S. J., Jones, R., Egan, B. J., Bonnet, C. S., Evans, S. L. and Mason, D. J. 2024. Investigating mechanical and inflammatory pathological mechanisms in osteoarthritis using MSC-derived osteocyte-like cells in 3D. Frontiers in Endocrinology 15, article number: 1359052. (10.3389/fendo.2024.1359052)
Conferences
- Hamilton, R. et al. 2023. Measuring osteoarthritis knee nociception using physiological and movement response and a defined thermal stimulus: A proof-of-concept study.. Presented at: The International Combined Orthopaedic Research Societies (ICORS), World Congress of Orthopaedic Research, Edinburgh, UK, 7-9 September 2022Orthopaedic Proceedings, Vol. 105-B,. pp. 20-20., (10.1302/1358-992X.2023.8.020)
- Hamilton, R., Holt, C., Jones, R., Shillabeer, D., Sparkes, V. and Mason, D. 2021. Measuring nociception in knee osteoarthritis using physiological and movement responses: a proof-of-concept study. Presented at: British Orthopaedic Research Society, Cardiff, UK, 13-14 September 2021.
Thesis
- Jones, R. 2024. Investigating the role of bone and nerve interactions in osteoarthritic pain and pathology. PhD Thesis, Cardiff University.