![Kimberley Marie Kendall](https://profiles-cardiff.imgix.net/attachments/6953?w=200&h=200&auto=format&crop=faces&fit=crop&q=90")
Overview
I am an academic psychiatrist passionate about using genetic and big data approaches to enhance patient care. My research focuses on genetic factors and their influence on illness outcomes in severe mental illness. I believe in the importance of translating research findings into patient care, and I take pride in being part of the team behind the All Wales Psychiatric Genomics Service, the UK's first dedicated psychiatric genomics clinic.
I completed higher psychiatry training in General Adult Psychiatry in South East Wales, with a subspecialty endorsement in Rehabilitation Psychiatry.
Publication
2024
- Kendall, K., Duffin, D., Doherty, J., Irving, R., Procter, A. and Walters, J. 2024. The translation of psychiatric genetics findings to the clinic. Schizophrenia Research 267, pp. 470-472. (10.1016/j.schres.2023.10.024)
2022
- Wadon, M., Fenner, E., Kendall, K., Bailey, G., Sandor, C., Rees, E. and Peall, K. J. 2022. Clinical and genotypic analysis in determining dystonia non-motor phenotypic heterogeneity: a UK Biobank study. Journal of Neurology 269, pp. 6436-6451. (10.1007/s00415-022-11307-4)
2021
- Kendall, K. M., Van Assche, E., Andlauer, T. F. M., Choi, K. W., Luykx, J. J., Schulte, E. C. and Lu, Y. 2021. The genetic basis of major depression. Psychological Medicine 51(13), pp. 2217-2230. (10.1017/S0033291721000441)
- Martin, J. et al. 2021. Examining sex differences in neurodevelopmental and psychiatric genetic risk in anxiety and depression. PLoS ONE 16(9), article number: e0248254. (10.1371/journal.pone.0248254)
- Silva, A. I. et al. 2021. Analysis of diffusion tensor imaging data from the UK Biobank confirms dosage effect of 15q11.2 copy number variation on white matter and shows association with cognition. Biological Psychiatry 90(5), pp. 307-316. (10.1016/j.biopsych.2021.02.969)
- Caseras, X. et al. 2021. Effects of genomic copy number variants penetrant for schizophrenia on cortical thickness and surface area in healthy individuals: analysis of the UK Biobank. British Journal of Psychiatry 218(2), pp. 104-111. (10.1192/bjp.2020.139)
- Kendall, K. 2021. The phenotypic expression of neuropsychiatric copy number variants. PhD Thesis, Cardiff University.
2020
- Kendall, K. M. et al. 2020. Impact of schizophrenia genetic liability on the association between schizophrenia and physical illness: a data linkage study. BJPsych Open 6(6), article number: e139. (10.1192/bjo.2020.42)
- Brcic, L., Underwood, J., Kendall, K., Caseras, X., Kirov, G. and Davies, W. 2020. Medical and neurobehavioural phenotypes in carriers of X-linked ichthyosis-associated genetic deletions in the UK Biobank. Journal of Medical Genetics 57(10), pp. 692-698. (10.1136/jmedgenet-2019-106676)
- Gubb, S., Brcic, L., Underwood, J., Kendall, K., Caseras, X., Kirov, G. and Davies, W. 2020. Medical and neurobehavioural phenotypes in male and female carriers of Xp22.31 duplications in the UK Biobank. Human Molecular Genetics 29(17), pp. 2872-2881. (10.1093/hmg/ddaa174)
- Warland, A., Kendall, K. M., Rees, E., Kirov, G. and Caseras, X. 2020. Schizophrenia-associated genomic copy number variants and subcortical brain volumes in the UK Biobank. Molecular Psychiatry 25(4), pp. 854-862. (10.1038/s41380-019-0355-y)
2019
- Legge, S. E. et al. 2019. Association of genetic liability to psychotic experiences with neuropsychotic disorders and traits. JAMA Psychiatry 76(12), pp. 1256-1265. (10.1001/jamapsychiatry.2019.2508)
- Escott-Price, V. et al. 2019. Polygenic risk for schizophrenia and season of birth within the UK Biobank cohort. Psychological Medicine 49(15), pp. 2499-2504. (10.1017/S0033291718000454)
- Underwood, J., Kendall, K., Berrett, J., Lewis, C., Anney, R., Van den Bree, M. and Hall, J. 2019. Autism spectrum disorder diagnosis in adults: phenotype and genotype findings from a clinically derived cohort. British Journal of Psychiatry 215(5), pp. 647-653. (10.1192/bjp.2019.30)
- Underwood, J., Kendall, K., Berrett, J., Anney, R., Bree, M. V. D. and Hall, J. 2019. SA20COPY Number variants and polygenic risk scores in adults with autism spectrum disorder (ASD): results from the NCMH adult ASD cohort. European Neuropsychopharmacology 29(S4), pp. S1198-S1199. (10.1016/j.euroneuro.2018.08.242)
- Kendall, K. M. et al. 2019. Cognitive performance and functional outcomes of carriers of pathogenic copy number variants: analysis of the UK Biobank. British Journal of Psychiatry 214(5), pp. 297-304. (10.1192/bjp.2018.301)
- Kendall, K. M. et al. 2019. Association of rare copy number variants with risk of depression. JAMA Psychiatry 76(8), pp. 818-825. (10.1001/jamapsychiatry.2019.0566)
- Crawford, K. et al. 2019. Medical consequences of pathogenic CNVs in adults: Analysis of the UK Biobank. Journal of Medical Genetics 56, pp. 131-138. (10.1136/jmedgenet-2018-105477)
2018
- Owen, D. et al. 2018. Effects of pathogenic CNVs on physical traits in participants of the UK Biobank. BMC Genomics 19(1), article number: 867. (10.1186/s12864-018-5292-7)
2017
- Cosgrove, D. et al. 2017. Cognitive characterization of schizophrenia risk variants involved in synaptic transmission: evidence of CACNA1C's role in working memory. Neuropsychopharmacology 42, pp. 2612-2622. (10.1038/npp.2017.123)
- Keynejad, R. C. et al. 2017. Docbate: a National Medical Student Debate. Academic Psychiatry 41(6), pp. 839-841. (10.1007/s40596-017-0697-1)
- Kendall, K. M. et al. 2017. Cognitive performance among carriers of pathogenic copy number variants: analysis of 152,000 UK Biobank subjects. Biological Psychiatry 82(2), pp. P103-110. (10.1016/j.biopsych.2016.08.014)
- McMillan, K. and Kendall, K. 2017. Basic genetics. Royal College of Psychiatrists. - teaching_resource
- Kendall, K. 2017. Clinical genetics. Royal College of Psychiatrists. - teaching_resource
- Kendall, K., Kirov, G. and Owen, M. 2017. Schizophrenia Genetics. In: Benjamin, S., Virginia, S. and Pedro, R. eds. Kaplan and Sadock?s Comprehensive Textbook of Psychiatry. Wolters Kluwer
2016
- Whitton, L. et al. 2016. Cognitive analysis of schizophrenia risk genes that function as epigenetic regulators of gene expression. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 171(8), pp. 1170-1179. (10.1002/ajmg.b.32503)
- Rees, E. et al. 2016. Analysis of intellectual disability copy number variants for association with schizophrenia. JAMA Psychiatry 73(9), pp. 963-969. (10.1001/jamapsychiatry.2016.1831)
2015
- Kendall, K. and Owen, M. J. 2015. Intellectual disability and psychiatric comorbidity: challenges and clinical issues. Psychiatric Times 32(5)
2012
- Kendall, K. and Robertson, N. 2012. Neuroimaging. Journal of Neurology 259(9), pp. 2009-2011. (10.1007/s00415-012-6652-x)
- Kendall, K., Thomas, R., Corkill, R. G. and Robertson, N. 2012. A neurological presentation of intravascular B-cell lymphoma. Case Reports (10.1136/bcr-2012-006439)
2009
- Carroll, L. S., Kendall, K., O'Donovan, M. C., Owen, M. J. and Williams, N. M. 2009. Evidence that putative ADHD low risk alleles atSNAP25may increase the risk of schizophrenia. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 150B(7), pp. 893-899. (10.1002/ajmg.b.30915)
Articles
- Kendall, K., Duffin, D., Doherty, J., Irving, R., Procter, A. and Walters, J. 2024. The translation of psychiatric genetics findings to the clinic. Schizophrenia Research 267, pp. 470-472. (10.1016/j.schres.2023.10.024)
- Wadon, M., Fenner, E., Kendall, K., Bailey, G., Sandor, C., Rees, E. and Peall, K. J. 2022. Clinical and genotypic analysis in determining dystonia non-motor phenotypic heterogeneity: a UK Biobank study. Journal of Neurology 269, pp. 6436-6451. (10.1007/s00415-022-11307-4)
- Kendall, K. M., Van Assche, E., Andlauer, T. F. M., Choi, K. W., Luykx, J. J., Schulte, E. C. and Lu, Y. 2021. The genetic basis of major depression. Psychological Medicine 51(13), pp. 2217-2230. (10.1017/S0033291721000441)
- Martin, J. et al. 2021. Examining sex differences in neurodevelopmental and psychiatric genetic risk in anxiety and depression. PLoS ONE 16(9), article number: e0248254. (10.1371/journal.pone.0248254)
- Silva, A. I. et al. 2021. Analysis of diffusion tensor imaging data from the UK Biobank confirms dosage effect of 15q11.2 copy number variation on white matter and shows association with cognition. Biological Psychiatry 90(5), pp. 307-316. (10.1016/j.biopsych.2021.02.969)
- Caseras, X. et al. 2021. Effects of genomic copy number variants penetrant for schizophrenia on cortical thickness and surface area in healthy individuals: analysis of the UK Biobank. British Journal of Psychiatry 218(2), pp. 104-111. (10.1192/bjp.2020.139)
- Kendall, K. M. et al. 2020. Impact of schizophrenia genetic liability on the association between schizophrenia and physical illness: a data linkage study. BJPsych Open 6(6), article number: e139. (10.1192/bjo.2020.42)
- Brcic, L., Underwood, J., Kendall, K., Caseras, X., Kirov, G. and Davies, W. 2020. Medical and neurobehavioural phenotypes in carriers of X-linked ichthyosis-associated genetic deletions in the UK Biobank. Journal of Medical Genetics 57(10), pp. 692-698. (10.1136/jmedgenet-2019-106676)
- Gubb, S., Brcic, L., Underwood, J., Kendall, K., Caseras, X., Kirov, G. and Davies, W. 2020. Medical and neurobehavioural phenotypes in male and female carriers of Xp22.31 duplications in the UK Biobank. Human Molecular Genetics 29(17), pp. 2872-2881. (10.1093/hmg/ddaa174)
- Warland, A., Kendall, K. M., Rees, E., Kirov, G. and Caseras, X. 2020. Schizophrenia-associated genomic copy number variants and subcortical brain volumes in the UK Biobank. Molecular Psychiatry 25(4), pp. 854-862. (10.1038/s41380-019-0355-y)
- Legge, S. E. et al. 2019. Association of genetic liability to psychotic experiences with neuropsychotic disorders and traits. JAMA Psychiatry 76(12), pp. 1256-1265. (10.1001/jamapsychiatry.2019.2508)
- Escott-Price, V. et al. 2019. Polygenic risk for schizophrenia and season of birth within the UK Biobank cohort. Psychological Medicine 49(15), pp. 2499-2504. (10.1017/S0033291718000454)
- Underwood, J., Kendall, K., Berrett, J., Lewis, C., Anney, R., Van den Bree, M. and Hall, J. 2019. Autism spectrum disorder diagnosis in adults: phenotype and genotype findings from a clinically derived cohort. British Journal of Psychiatry 215(5), pp. 647-653. (10.1192/bjp.2019.30)
- Underwood, J., Kendall, K., Berrett, J., Anney, R., Bree, M. V. D. and Hall, J. 2019. SA20COPY Number variants and polygenic risk scores in adults with autism spectrum disorder (ASD): results from the NCMH adult ASD cohort. European Neuropsychopharmacology 29(S4), pp. S1198-S1199. (10.1016/j.euroneuro.2018.08.242)
- Kendall, K. M. et al. 2019. Cognitive performance and functional outcomes of carriers of pathogenic copy number variants: analysis of the UK Biobank. British Journal of Psychiatry 214(5), pp. 297-304. (10.1192/bjp.2018.301)
- Kendall, K. M. et al. 2019. Association of rare copy number variants with risk of depression. JAMA Psychiatry 76(8), pp. 818-825. (10.1001/jamapsychiatry.2019.0566)
- Crawford, K. et al. 2019. Medical consequences of pathogenic CNVs in adults: Analysis of the UK Biobank. Journal of Medical Genetics 56, pp. 131-138. (10.1136/jmedgenet-2018-105477)
- Owen, D. et al. 2018. Effects of pathogenic CNVs on physical traits in participants of the UK Biobank. BMC Genomics 19(1), article number: 867. (10.1186/s12864-018-5292-7)
- Cosgrove, D. et al. 2017. Cognitive characterization of schizophrenia risk variants involved in synaptic transmission: evidence of CACNA1C's role in working memory. Neuropsychopharmacology 42, pp. 2612-2622. (10.1038/npp.2017.123)
- Keynejad, R. C. et al. 2017. Docbate: a National Medical Student Debate. Academic Psychiatry 41(6), pp. 839-841. (10.1007/s40596-017-0697-1)
- Kendall, K. M. et al. 2017. Cognitive performance among carriers of pathogenic copy number variants: analysis of 152,000 UK Biobank subjects. Biological Psychiatry 82(2), pp. P103-110. (10.1016/j.biopsych.2016.08.014)
- Whitton, L. et al. 2016. Cognitive analysis of schizophrenia risk genes that function as epigenetic regulators of gene expression. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 171(8), pp. 1170-1179. (10.1002/ajmg.b.32503)
- Rees, E. et al. 2016. Analysis of intellectual disability copy number variants for association with schizophrenia. JAMA Psychiatry 73(9), pp. 963-969. (10.1001/jamapsychiatry.2016.1831)
- Kendall, K. and Owen, M. J. 2015. Intellectual disability and psychiatric comorbidity: challenges and clinical issues. Psychiatric Times 32(5)
- Kendall, K. and Robertson, N. 2012. Neuroimaging. Journal of Neurology 259(9), pp. 2009-2011. (10.1007/s00415-012-6652-x)
- Kendall, K., Thomas, R., Corkill, R. G. and Robertson, N. 2012. A neurological presentation of intravascular B-cell lymphoma. Case Reports (10.1136/bcr-2012-006439)
- Carroll, L. S., Kendall, K., O'Donovan, M. C., Owen, M. J. and Williams, N. M. 2009. Evidence that putative ADHD low risk alleles atSNAP25may increase the risk of schizophrenia. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 150B(7), pp. 893-899. (10.1002/ajmg.b.30915)
Book sections
- Kendall, K., Kirov, G. and Owen, M. 2017. Schizophrenia Genetics. In: Benjamin, S., Virginia, S. and Pedro, R. eds. Kaplan and Sadock?s Comprehensive Textbook of Psychiatry. Wolters Kluwer
Thesis
- Kendall, K. 2021. The phenotypic expression of neuropsychiatric copy number variants. PhD Thesis, Cardiff University.
teaching_resource
- McMillan, K. and Kendall, K. 2017. Basic genetics. Royal College of Psychiatrists. - teaching_resource
- Kendall, K. 2017. Clinical genetics. Royal College of Psychiatrists. - teaching_resource
Research
My research focuses on genetic factors and their influence on illness outcomes in severe mental illness. I believe in the importance of translating research findings into patient care, and I take pride in being part of the team behind the All Wales Psychiatric Genomics Service, the UK's first dedicated psychiatric genomics clinic.
Teaching
I teach psychiatry on the Cardiff University Medicine MBBCh course, including small group teaching on suicide and self harm and communication skills. I also examine formative and summative psychiatry ISCE examinations. I am an academic mentor to students on the course and I'm involved in peer review for scientific journals.
Biography
Senior Clinical Fellow, Mental Health Mission, Cardiff University
September 2024 – present
Early Psychosis Workstream, Mental Health Mission
- I work with workstream members to develop our study protocols, harmonising these with related studies.
- I liaise with the broader Mental Health Mission, including presenting to industry partners
- I mentor two F3 doctors employed by the workstream, helping them develop their career goals and leadership skills.
Early Psychosis Multi-arm, Multi-stage Platform Trial (PUMA)
- I am a member of the Infrastructure Working Group of PUMA and am currently working with PUMA members to conduct a systematic review.
CONNECT Study of Wearable Technology in Psychosis, Wellcome Trust
- I co-lead Wales recruitment for three health boards for this UK-wide study.
- I line manage our CONNECT Research Coordinator.
All Wales Psychiatric Genomics Service
- I work alongside a clinical geneticist, genetic counsellor, and fellow psychiatrists to run this service, which includes patient appointments, clinical outreach work, and service evaluations.
2021 - 2024, Higher Training Adult Psychiatry, Wales Clinical Academic Track
- ST6, Early Intervention in Psychosis Team, Cardiff and Vale UHBs.
- ST5, Merthyr Tydfil CMHT, Cwm Taf Morgannwg UHB.
- ST4, Outreach and Recovery Team North / Pinewood House Rehabilitation Unit, Cwm Taf Morgannwg UHB.
2020 - 2021, Core Psychiatry Training, Wales Clinical Academic Track
- CT3, Cwm Taf Morgannwg UHB.
2017 - 2020, Wellcome Trust Clinical Research Fellow, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University.
2013 - 2017, Core Psychiatry Training, Wales Clinical Academic Track
- CT1 - 2, Cardiff and Vale UHB.
2011 - 2013, Core Medical Training, Cwm Taf and Cardiff and Vale UHBs.
2009 - 2011, Foundation Programme, Aneurin Bevan and Cardiff and Vale UHBs.
Honours and awards
2024, Royal College of Psychiatrists Early Career Researcher of the Year - shortlisted (result awaited November 2024).
2024, Senior Clinical Fellowship (£140,000), Mental Health Mission.
2024, RCPsych International Congress bursary, RCPsych Wales Bursary.
2024, Training course attendance fee, Future Leaders in Psychosis Research Award.
2022, Return of pathogenic CNV results to NCMH participants, Mental Health Incubator Award - Early impact category.
2020, The role of neurodevelopmental copy number variants in depression, European Psychiatric Society Research Prize.
2018, Two abstracts in the top 20 entries, UK Biobank Early Career Researcher of the Year Competition.
2016, PhD fellowship (£202,982.66), Wellcome Trust Clinical Research Training Fellowship.
Professional memberships
Certificate of Completion of Specialist Training - General Adult Psychiatry, Endorsement in Rehabilitation Psychiatry.
Member of the Royal College of Psychiatrists (MRCPsych)
Registered with the General Medical Council (7047089)
Speaking engagements
- Clinical translation of psychiatric genetic findings, British Neuroscience Society and the Senedd (2024).
- The All Wales Psychiatric Genomics Service, East London Foundation NHS Trust (2024).
- Copy number variants in general adult psychiatry and their translation to the clinic, SGDP Centre, King's College London (2023).
- Copy number variants in general adult psychiatry and their translation to the clinic, American Academy of Child and Adolescent Psychiatry Meeting (2022).
- Copy number variation and their interaction with polygenic risk scores in psychiatric disorders, World Congress of Psychiatric Genetics, Florence (2022).
- Organiser and chair, British Journal of Psychiatry Journal Club Cymru (2022).
- Copy number variants in general adult psychiatry, Department of Psychiatry, Cambridge University (2022).
- Examination of the role genetic liability to schizophrenia plays in physical illness, via linkage to NHS records; Genomics café – the role of rare CNVs in psychiatric disorders, All Wales Genomics Showcase (2021).
- The return of neurodevelopmental CNV results to research participants – ethical issues and protocol development, World Congress of Psychiatric Genetics (2020).
- The genetics of mental health – rare CNVs, Royal Society of Medicine Webinar (2020).
- An introduction to the depression phenotype and its epidemiology - team presentation, Psychiatric Genomics Consortium Worldwide Lab (2020).
- The phenotypic expression of neuropsychiatric CNVs, SGDP Centre, King’s College London (2020).
Committees and reviewing
2024 – present, Member of the Editorial Board of Discover Mental Health.
2022 - present, PhD examiner
- Cardiff University (internal examiner).
- King’s College London (external examiner).
- University of Montreal (external examiner).
2021 - present, Mentor, Women in Healthcare Society Mentorship Scheme, Barts and the London Medical School.
2022 - present, Committee member
- Membership Committee, International Society of Psychiatric Genetics.
2018 - 2024, Outreach Liaison, Schizophrenia Group, Psychiatric Genomics Consortium.
Ongoing, Peer review activity
- PLoS One, Journal of Psychiatric Research, Journal of Affective Disorders, Psychological Medicine, British Journal of Psychiatry, Biological Psychiatry, Scientific Reports, Molecular Psychiatry, JAMA Psychiatry, Clinical Genetics.
2015 - 2022, Academic mentor, Medicine MBBCh course, Cardiff University.
Contact Details
KendallKM@cardiff.ac.uk
+44 29206 88418
Hadyn Ellis Building, Room 2.01, Maindy Road, Cardiff, CF24 4HQ
+44 29206 88418
Hadyn Ellis Building, Room 2.01, Maindy Road, Cardiff, CF24 4HQ
Research themes
Specialisms
- Psychiatric Genetics
- Clinical Translation