Skip to main content
Sophie Legge

Dr Sophie Legge

(she/her)

Research Fellow, Division of Psychological Medicine and Clinical Neurosciences

Overview

My research is primarily focused on the contribution of genetic and environmental factors to the development of psychosis and schizophrenia.

I am interested in dissecting the heterogeneity and dimensionality of schizophrenia by identifying biologically valid phenotypic constructs.

I am also interested in pharmacogenetics, specifically in relation to clozapine use and the Duffy-null genetic variant. My PhD (completed in 2016) was focused on identifying predictors of treatment-resistant schizophrenia, and the genetic causes of clozapine-induced neutropenia, a rare adverse effect of the antipsychotic clozapine.

Publication

2024

2023

2022

2021

2020

2019

2018

2017

2016

2015

2014

2013

2012

Articles

Thesis

Websites

Contact Details

Email LeggeSE8@cardiff.ac.uk
Telephone +44 29206 88387
Campuses Hadyn Ellis Building, Room 2.30, Maindy Road, Cardiff, CF24 4HQ