Bethan Mansfield
(she/her)
Centre Manager
Publication
2025
- Wolffs, K. et al. 2025. Calcium-sensing receptor as a novel target for the treatment of idiopathic pulmonary fibrosis. Biomolecules 15(4), article number: 509. (10.3390/biom15040509)
2022
- Mansfield, B. 2022. The Calcium-Sensing Receptor (CaSR) as a potential mediator of pollution-induced airway cell responses. PhD Thesis, Cardiff University.
2021
- Schepelmann, M. et al. 2021. Stereo-specific modulation of the extracellular calcium-sensing receptor in colon cancer cells. International Journal of Molecular Sciences 22(18), article number: 10124. (10.3390/ijms221810124)
Articles
- Wolffs, K. et al. 2025. Calcium-sensing receptor as a novel target for the treatment of idiopathic pulmonary fibrosis. Biomolecules 15(4), article number: 509. (10.3390/biom15040509)
- Schepelmann, M. et al. 2021. Stereo-specific modulation of the extracellular calcium-sensing receptor in colon cancer cells. International Journal of Molecular Sciences 22(18), article number: 10124. (10.3390/ijms221810124)
Thesis
- Mansfield, B. 2022. The Calcium-Sensing Receptor (CaSR) as a potential mediator of pollution-induced airway cell responses. PhD Thesis, Cardiff University.
Biography
Beth gained her PhD in Biomedical sciences from Cardiff University where she discovered a novel mechanism underpinning how our lungs sense and respond to the often polluted world around us. Her PhD focused on better understanding the impacts of particulate matter, one of the major components of air pollution, on airways structural and immune cells and how we can target pathological mechanisms using a new treatment for a range of lung diseases, called negative allosteric modulators (NAMs) at the calcium-sensing receptor (CaSR) or calcilytics.
Beth now manages the OneZoo Centre for Doctoral Training (www.onezoo.uk), a £7.2M initiative to tackle infectious disease worldwide funded by NERC, BBSRC and the MRC. Our transdisciplinary OneZoo Centre for Doctoral Training (CDT) will equip the next generation of world-leading scientists with the skills and insight necessary to tackle current and future zoonotic threats. Our aim is to design successful, innovative environmental prevention and control strategies, as zoonotic drivers need to be understood through an integrated systems approach. Our students will build an in-depth understanding of the connectivity between key drivers of pathogen host shifts, spillover and onward transmission; exploring pathogen, environmental and human societal processes that can promote zoonotic disease and form the basis of integrated solutions.
Alongside her role as the manager of OneZoo, she is an active post-doc including in Prof Jo Cable's aquatics lab, leveraging her PhD findings to better understand the mechanisms behind environmental drivers of diseases in different ecosystems.