Dr Pawan Kumar Mishra
Postdoctoral Research Associate (with Dr Matthew Tredwelll)
- MishraP2@cardiff.ac.uk
- 54 Park Place, Room 1.85, Cathays, Cardiff, CF10 3AT
Overview
I have completed my postgraduate studies from the Indian Institute of Technology, Delhi (India) with specialization in Organic chemistry. Later, I moved to University of Delhi to pursue my Ph. D. under supervision of Prof. Akhilesh Verma research group which is dedicated in development of synthetic methodology and target Synthesis of biological relevant heterocyclic compounds. I have been awarded my Ph. D. in October 2019 and continued work in the group as Research Associate till March 2021. During my Ph.D. and postgraduate studies, I have gained a strong experience in the field of synthetic organic chemistry, characterization and mechanistic investigation. My expertise is in the area of multistep organic synthesis, alkyne annulation, C-H activation. I am working as Research Associate in MT group.
Publication
2022
- Dwivedi, B., Mishra, P. K. and Mishra, V. 2022. Chiral metal-organic frameworks for asymmetrical catalysis. In: Gulati, S. ed. Metal-Organic Frameworks (MOFs) as Catalysts. Singapore: Springer, pp. 493–513., (10.1007/978-981-16-7959-9_19)
2021
- Kumar, A., Mishra, P. K., Saini, K. M. and Verma, A. K. 2021. Base‐promoted synthesis of polysubstituted 4‐aminoquinolines from ynones and 2‐aminobenzonitriles under transition‐metal‐free conditions. Advanced Synthesis and Catalysis 363(10), pp. 2546-2551. (10.1002/adsc.202100023)
2020
- Mishra, P. K., Chatterjee, S. and Verma, A. K. 2020. 2-Alkynylarylnitrile: an emerging precursor for the generation of carbo- and heterocycles. ACS Omega 5(50), pp. 32133-32139. (10.1021/acsomega.0c04242)
- Salunke, R. V., Mishra, P. K., Sanghvi, Y. S. and Ramesh, N. G. 2020. Synthesis of novel homoazanucleosides and their peptidyl analogs. Organic and Biomolecular Chemistry 18(29), pp. 5639-5651. (10.1039/D0OB01046D)
- Mishra, P. K., Kumar, A. and Verma, A. 2020. BF3-Etherate-catalyzed tandem reaction of 2-formylarylketones with electron-rich arenes/heteroarenes: an assembly of isobenzofurans. Chemical Communications 56(45), pp. 6122-6125. (10.1039/D0CC02760J)
2019
- Kumar, M., Verma, S., Kumar, A., Mishra, P. K., Ramabhadran, R. O., Banerjee, S. and Verma, A. K. 2019. Mechanistic insights of Cu(II)-mediated ortho-C--H amination of arenes by capturing fleeting intermediates and theoretical calculations. Chemical Communications 55(63), pp. 9359-9362. (10.1039/C9CC04317A)
- Mishra, P. K., Verma, S., Kumar, M., Kumar, A. and Verma, A. K. 2019. Harnessing the reactivity of ortho-formyl-arylketones: base-promoted regiospecific synthesis of functionalized isoquinolines. Chemical Communications 55(57), pp. 8278-8281. (10.1039/c9cc03689j)
- Verma, S., Kumar, M., Mishra, P. K. and Verma, A. K. 2019. Metal-free carbonyl-assisted regioselective hydration of alkynes: an access to dicarbonyls. Organic Letters 21(13), pp. 5059-5063. (10.1021/acs.orglett.9b01649)
- Kumar, M., Verma, S., Mishra, P. and Verma, A. 2019. Cu(II)-mediated ortho-C-H amination of arenes with free amines. Journal of Organic Chemistry 84(12), pp. 8067-8079. (10.1021/acs.joc.9b00931)
2018
- Mishra, P. K., Verma, S., Kumar, M. and Verma, A. 2018. Base-mediated direct transformation of N-propargylamines into 2,3,5-trisubstituted 1 H-pyrroles. Organic Letters 20(22), pp. 7182-7185. (10.1021/acs.orglett.8b03112)
- Verma, S., Mishra, P. K., Kumar, M., Sur, S. and Verma, A. 2018. Transition-metal-free access to pyridocarbazoles from 2-alkynylindole-3-carbaldehydes via azomethine ylide. Journal of Organic Chemistry 83(12), pp. 6650-6663. (10.1021/acs.joc.8b00980)
2016
- Mishra, P. K. and Verma, A. K. 2016. Metal-free regioselective tandem synthesis of diversely substituted benzimidazo-fused polyheterocycles in aqueous medium. Green Chemistry 18(23), pp. 6367-6372. (10.1039/c6gc02330d)
Articles
- Kumar, A., Mishra, P. K., Saini, K. M. and Verma, A. K. 2021. Base‐promoted synthesis of polysubstituted 4‐aminoquinolines from ynones and 2‐aminobenzonitriles under transition‐metal‐free conditions. Advanced Synthesis and Catalysis 363(10), pp. 2546-2551. (10.1002/adsc.202100023)
- Mishra, P. K., Chatterjee, S. and Verma, A. K. 2020. 2-Alkynylarylnitrile: an emerging precursor for the generation of carbo- and heterocycles. ACS Omega 5(50), pp. 32133-32139. (10.1021/acsomega.0c04242)
- Salunke, R. V., Mishra, P. K., Sanghvi, Y. S. and Ramesh, N. G. 2020. Synthesis of novel homoazanucleosides and their peptidyl analogs. Organic and Biomolecular Chemistry 18(29), pp. 5639-5651. (10.1039/D0OB01046D)
- Mishra, P. K., Kumar, A. and Verma, A. 2020. BF3-Etherate-catalyzed tandem reaction of 2-formylarylketones with electron-rich arenes/heteroarenes: an assembly of isobenzofurans. Chemical Communications 56(45), pp. 6122-6125. (10.1039/D0CC02760J)
- Kumar, M., Verma, S., Kumar, A., Mishra, P. K., Ramabhadran, R. O., Banerjee, S. and Verma, A. K. 2019. Mechanistic insights of Cu(II)-mediated ortho-C--H amination of arenes by capturing fleeting intermediates and theoretical calculations. Chemical Communications 55(63), pp. 9359-9362. (10.1039/C9CC04317A)
- Mishra, P. K., Verma, S., Kumar, M., Kumar, A. and Verma, A. K. 2019. Harnessing the reactivity of ortho-formyl-arylketones: base-promoted regiospecific synthesis of functionalized isoquinolines. Chemical Communications 55(57), pp. 8278-8281. (10.1039/c9cc03689j)
- Verma, S., Kumar, M., Mishra, P. K. and Verma, A. K. 2019. Metal-free carbonyl-assisted regioselective hydration of alkynes: an access to dicarbonyls. Organic Letters 21(13), pp. 5059-5063. (10.1021/acs.orglett.9b01649)
- Kumar, M., Verma, S., Mishra, P. and Verma, A. 2019. Cu(II)-mediated ortho-C-H amination of arenes with free amines. Journal of Organic Chemistry 84(12), pp. 8067-8079. (10.1021/acs.joc.9b00931)
- Mishra, P. K., Verma, S., Kumar, M. and Verma, A. 2018. Base-mediated direct transformation of N-propargylamines into 2,3,5-trisubstituted 1 H-pyrroles. Organic Letters 20(22), pp. 7182-7185. (10.1021/acs.orglett.8b03112)
- Verma, S., Mishra, P. K., Kumar, M., Sur, S. and Verma, A. 2018. Transition-metal-free access to pyridocarbazoles from 2-alkynylindole-3-carbaldehydes via azomethine ylide. Journal of Organic Chemistry 83(12), pp. 6650-6663. (10.1021/acs.joc.8b00980)
- Mishra, P. K. and Verma, A. K. 2016. Metal-free regioselective tandem synthesis of diversely substituted benzimidazo-fused polyheterocycles in aqueous medium. Green Chemistry 18(23), pp. 6367-6372. (10.1039/c6gc02330d)
Book sections
- Dwivedi, B., Mishra, P. K. and Mishra, V. 2022. Chiral metal-organic frameworks for asymmetrical catalysis. In: Gulati, S. ed. Metal-Organic Frameworks (MOFs) as Catalysts. Singapore: Springer, pp. 493–513., (10.1007/978-981-16-7959-9_19)
- Kumar, A., Mishra, P. K., Saini, K. M. and Verma, A. K. 2021. Base‐promoted synthesis of polysubstituted 4‐aminoquinolines from ynones and 2‐aminobenzonitriles under transition‐metal‐free conditions. Advanced Synthesis and Catalysis 363(10), pp. 2546-2551. (10.1002/adsc.202100023)
- Mishra, P. K., Chatterjee, S. and Verma, A. K. 2020. 2-Alkynylarylnitrile: an emerging precursor for the generation of carbo- and heterocycles. ACS Omega 5(50), pp. 32133-32139. (10.1021/acsomega.0c04242)
- Salunke, R. V., Mishra, P. K., Sanghvi, Y. S. and Ramesh, N. G. 2020. Synthesis of novel homoazanucleosides and their peptidyl analogs. Organic and Biomolecular Chemistry 18(29), pp. 5639-5651. (10.1039/D0OB01046D)
- Mishra, P. K., Kumar, A. and Verma, A. 2020. BF3-Etherate-catalyzed tandem reaction of 2-formylarylketones with electron-rich arenes/heteroarenes: an assembly of isobenzofurans. Chemical Communications 56(45), pp. 6122-6125. (10.1039/D0CC02760J)
- Kumar, M., Verma, S., Kumar, A., Mishra, P. K., Ramabhadran, R. O., Banerjee, S. and Verma, A. K. 2019. Mechanistic insights of Cu(II)-mediated ortho-C--H amination of arenes by capturing fleeting intermediates and theoretical calculations. Chemical Communications 55(63), pp. 9359-9362. (10.1039/C9CC04317A)
- Mishra, P. K., Verma, S., Kumar, M., Kumar, A. and Verma, A. K. 2019. Harnessing the reactivity of ortho-formyl-arylketones: base-promoted regiospecific synthesis of functionalized isoquinolines. Chemical Communications 55(57), pp. 8278-8281. (10.1039/c9cc03689j)
- Verma, S., Kumar, M., Mishra, P. K. and Verma, A. K. 2019. Metal-free carbonyl-assisted regioselective hydration of alkynes: an access to dicarbonyls. Organic Letters 21(13), pp. 5059-5063. (10.1021/acs.orglett.9b01649)
- Kumar, M., Verma, S., Mishra, P. and Verma, A. 2019. Cu(II)-mediated ortho-C-H amination of arenes with free amines. Journal of Organic Chemistry 84(12), pp. 8067-8079. (10.1021/acs.joc.9b00931)
- Mishra, P. K., Verma, S., Kumar, M. and Verma, A. 2018. Base-mediated direct transformation of N-propargylamines into 2,3,5-trisubstituted 1 H-pyrroles. Organic Letters 20(22), pp. 7182-7185. (10.1021/acs.orglett.8b03112)
- Verma, S., Mishra, P. K., Kumar, M., Sur, S. and Verma, A. 2018. Transition-metal-free access to pyridocarbazoles from 2-alkynylindole-3-carbaldehydes via azomethine ylide. Journal of Organic Chemistry 83(12), pp. 6650-6663. (10.1021/acs.joc.8b00980)
Biography
Education | |
2014 –2019 | PhD in Organic Chemistry, Department of Chemistry, University of Delhi, Delhi, India |
2012– 2014 | M. Tech Molecular Engineering, Chemical Synthesis & Analysis, Indian Institute of Technology, Delhi, India |
2009-2011 | M. Sc in Chemistry, CSJM University, Kanpur, Uttar Pradesh, India |
Honours and awards
- CSIR-RA Award (2020)
- SaiLife-NOST Best Thesis Award (2019)
- Elsevier Best oral Presentation Award
- Elsevier Young scientist oral Presentation Award
- Organic & Biomolecular Chemistry Poster Presentation Prize
- S. K. Talapatra Award for best poster in the Organic &Biomolecular Chemistry