Dr Ned Powell

BSc (Hons), PhD

2023

• Hassoulas, A., Powell, N., Roberts, L. and Umla-Runge, K. 2023. Investigating marker accuracy in differentiating between student scripts and those produced using ChatGPT. Presented at: AI in Education, Cardiff University, 29 June 2023. Journal of Applied Learning & Teaching, (10.37074/jalt.2023.6.2.13)
• Hassoulas, A., Powell, N., Roberts, L., Umla-Runge, K., Gray, L. and Coffey, M. 2023. Investigating marker accuracy in differentiating between university scripts written by students and those produced using ChatGPT. Journal of Applied Learning & Teaching 6(2) (10.37074/jalt.2023.6.2.13)

2022

• Hurt, C. N., Nedjai, B., Alvarez-Mendoza, C., Powell, N., Tristram, A. and Jones, S. 2022. Combined HPV 16 E2 and L1 methylation predict response to treatment with cidofovir and imiquimod in patients with vulval intraepithelial neoplasia. Cancer Biomarkers 35, pp. 143-153. (10.3233/CBM-210448)

2020

• Holzhauser, S. et al. 2020. Sensitivity of human papillomavirus-positive and -negative oropharyngeal cancer cell lines to ionizing irradiation. Oncology Reports (10.3892/or.2020.7709)

2018

• Pirotte, E. F. et al. 2018. Sensitivity to inhibition of DNA repair by Olaparib in novel oropharyngeal cancer cell lines infected with Human Papillomavirus. PLoS ONE 13(12), pp. -., article number: e0207934. (10.1371/journal.pone.0207934)
• Hurt, C. N. et al. 2018. Recurrence of vulval intraepithelial neoplasia following treatment with cidofovir or imiquimod: results from a multi-centre, randomised, phase II trial (RT3VIN). BJOG: An International Journal of Obstetrics and Gynaecology 125(9), pp. 1171-1177. (10.1111/1471-0528.15124)

2017

• Jones, S. E. F., Hibbitts, S., Hurt, C. N., Bryant, D., Fiander, A. N., Powell, N. and Tristram, A. J. 2017. Human Papillomavirus DNA methylation predicts response to treatment using cidofovir and imiquimod in Vulval Intraepithelial Neoplasia 3. Clinical Cancer Research 23(18), pp. 5460-5468. (10.1158/1078-0432.CCR-17-0040)

2016

• Schache, A. G. et al. 2016. HPV-related oropharynx cancer in the United Kingdom: An evolution in the understanding of disease etiology. Cancer Research 76(22), pp. 6598-6606. (10.1158/0008-5472.CAN-16-0633)
• Mehanna, H. et al. 2016. PET-CT Surveillance versus Neck Dissection in Advanced Head and Neck Cancer. New England Journal of Medicine 374(15), pp. 1444-1454. (10.1056/NEJMoa1514493)
• Sacco, J. J., Evans, M., Harrington, K. J., Man, S., Powell, N., Shaw, R. J. and Jones, T. M. 2016. Systemic listeriosis following vaccination with the attenuatedListeria monocytogenestherapeutic vaccine, ADXS11-001. Human Vaccines & Immunotherapeutics 12(4), pp. 1085-1086. (10.1080/21645515.2015.1121338)
• Hibbitts, S., Powell, N., Newton, Z., Patel, S. and Hart, K. 2016. Student selected project opportunities with C21 MB BCh. Presented at: C4ME Educator Development Day, Cardiff University, Cardiff, UK, 2016.

2015

• Holl, K. et al. 2015. Human papillomavirus prevalence and type-distribution in cervical glandular neoplasias: results from a European multinational epidemiological study. International Journal of Cancer 137(12), pp. 2858-2868. (10.1002/ijc.29651)
• Owadally, W. et al. 2015. PATHOS: a phase II/III trial of risk-stratified, reduced intensity adjuvant treatment in patients undergoing transoral surgery for Human papillomavirus (HPV) positive oropharyngeal cancer. BMC Cancer 15, article number: 602. (10.1186/s12885-015-1598-x)
• Bryant, D., Hibbitts, S. J., Almonte, M., Tristram, A. J., Fiander, A. N. and Powell, N. G. 2015. Human papillomavirus type 16 L1/L2 DNA methylation shows weak association with cervical disease grade in young women. Journal of Clinical Virology 66, pp. 66-71. (10.1016/j.jcv.2015.03.001)
• Powell, N. G. and Evans, M. 2015. Human papillomavirus-associated head and neck cancer: oncogenic mechanisms, epidemiology and clinical behaviour. Diagnostic Histopathology 21(2), pp. 49-64. (10.1016/j.mpdhp.2015.02.003)

2014

• Tristram, A. et al. 2014. Activity, safety, and feasibility of cidofovir and imiquimod for treatment of vulval intraepithelial neoplasia (RT³VIN): a multicentre, open-label, randomised, phase 2 trial. Lancet Oncology 15(12), pp. 1361-1368. (10.1016/S1470-2045(14)70456-5)
• Palmer, E. et al. 2014. Human papillomavirus infection is rare in nonmalignant tonsil tissue in the UK: implications for tonsil cancer precursor lesions. International Journal of Cancer 135(10), pp. 2437-2443. (10.1002/ijc.28886)
• Bryant, D. et al. 2014. Increased methylation of Human Papillomavirus type 16 DNA correlates with viral integration in Vulval Intraepithelial Neoplasia. Journal of Clinical Virology 61(3), pp. 393-399. (10.1016/j.jcv.2014.08.006)
• Evans, M. and Powell, N. 2014. Sexual health in oral oncology: breaking the news to patients with human papillomavirus-positive oropharyngeal cancer. Head and Neck 36(11), pp. 1529-1533. (10.1002/hed.23792)
• Bryant, D. et al. 2014. mRNA sequencing of novel cell lines from human papillomavirus type-16 related vulval intraepithelial neoplasia: Consequences of expression of HPV16 E4 and E5. Journal of Medical Virology 86(9), pp. 1534-1541. (10.1002/jmv.23994)
• Pertusati, F., Hinsinger, K., Flynn, ?. S., Powell, N. G., Tristram, A. J., Balzarini, J. and McGuigan, C. 2014. PMPA and PMEA prodrugs for the treatment of HIV infections and human papillomavirus (HPV) associated neoplasia and cancer. European Journal of Medicinal Chemistry 78, pp. 259-268. (10.1016/j.ejmech.2014.03.051)
• Caley, A. et al. 2014. Multicentric human papillomavirus-associated head and neck squamous cell carcinoma. Head and Neck-Journal for the Sciences and Specialties of the Head and Neck 37(2), pp. 202-208. (10.1002/hed.23584)
• Bryant, D., Tristram, A., Liloglou, T., Hibbitts, S., Fiander, A. and Powell, N. 2014. Quantitative measurement of Human Papillomavirus type 16 L1/L2 DNA methylation correlates with cervical disease grade. Journal of Clinical Virology 59(1), pp. 24-29. (10.1016/j.jcv.2013.10.029)

2013

• Al-Taei, S., Banner, R., Powell, N. G., Evans, M., Palaniappan, N., Tabi, Z. and Man, S. T. 2013. Decreased HPV-specific T cell responses and accumulation of immunosuppressive influences in oropharyngeal cancer patients following radical therapy. Cancer Immunology, Immunotherapy 62(12), pp. 1821-1830. (10.1007/s00262-013-1488-5)
• Powell, N. G. et al. 2013. Cervical cancers associated with human papillomavirus types 16, 18 and 45 are diagnosed in younger women than cancers associated with other types: A cross-sectional observational study in Wales and Scotland (UK). Journal of Clinical Virology 58(3), pp. 571-574. (10.1016/j.jcv.2013.08.020)
• Lorincz, A. T. et al. 2013. HPV16 L1 and L2 DNA methylation predicts high-grade cervical intraepithelial neoplasia in women with mildly abnormal cervical cytology. International Journal of Cancer 133(3), pp. 637-644. (10.1002/ijc.28050)
• Borst, G. et al. 2013. Targeted radiosensitization by the Chk1 inhibitor SAR-020106. International Journal of Radiation Oncology - Biology - Physics 85(4), pp. 1110-1118. (10.1016/j.ijrobp.2012.08.006)

2011

• Bryant, D. et al. 2011. Human papillomavirus type distribution in vulval intraepithelial neoplasia determined using PapilloCheck DNA Microarray. Journal of Medical Virology 83(8), pp. 1358-1361. (10.1002/jmv.22107)
• Powell, N. G., Hibbitts, S. J., Boyde, A., Newcombe, R. G., Tristram, A. J. and Fiander, A. N. 2011. The risk of cervical cancer associated with specific types of human papillomavirus: a case-control study in a UK population. International Journal of Cancer 128(7), pp. 1676-1682. (10.1002/ijc.25485)
• Jones, J. et al. 2011. Human papillomavirus genotype testing combined with cytology as a 'test of cure' post treatment: the importance of a persistent viral infection. Journal of Clinical Virology 52(2), pp. 88-92. (10.1016/j.jcv.2011.06.021)

2010

• Jones, J. et al. 2010. Human papillomavirus prevalence in women treated for high-grade cervical intraepithelial neoplasia (CIN) [Abstract]. Acta Cytologica 54(3), pp. 429-429.
• Jones, J. et al. 2010. P1-023 Human papillomavirus prevalence in women treated for high-grade cervical intraepithelial neoplasia (CIN) [Abstract]. Acta Cytologica 54(3), pp. 429.
• Powell, N. G. 2010. Single HPV test not useful for predicting CIN2 or worse or for guiding choice of further investigations for women aged 20-59 presenting to NHS Cervical Screening Programme with borderline abnormalities or mild dyskaryosis. Evidence-Based Medicine 15(6), pp. 182-183. (10.1136/ebm1111)
• Evans, M. and Powell, N. G. 2010. The changing aetiology of head and neck cancer: the role of human papillomavirus. Clinical Oncology 22(7), pp. 538-546. (10.1016/j.clon.2010.05.024)

2009

• Jones, J., Powell, N. G., Tristram, A. J., Fiander, A. N. and Hibbitts, S. J. 2009. Comparison of the PapilloCheck® DNA micro-array human papillomavirus detection assay with hybrid capture II and PCR-enzyme immunoassay using the GP5/6+ primer set. Journal of Clinical Virology 45(2), pp. 100-104. (10.1016/j.jcv.2009.02.013)
• Powell, N. G., Boyde, A. M., Tristram, A. J., Hibbitts, S. J. and Fiander, A. N. 2009. The potential impact of human papillomavirus vaccination in contemporary cytologically screened populations may be underestimated: an observational retrospective analysis of invasive cervical cancers. International Journal of Cancer 125(10), pp. 2425-2427. (10.1002/ijc.24571)

2008

• Rai, N., Jenkins, G. J. S., McAdam, E., Hibbitts, S. J., Fiander, A. N. and Powell, N. G. 2008. Human papillomavirus infection in Barrett's oesophagus in the UK: an infrequent event. Journal of Clinical Virology 43(2), pp. 250-252. (10.1016/j.jcv.2008.07.004)
• Hughes, D. S., Powell, N. G. and Fiander, A. N. 2008. Will vaccination against human papillomavirus prevent eye disease? A review of the evidence. British Journal of Ophthalmology 92(4), pp. 460-465. (10.1136/bjo.2007.135038)

2006

• Powell, N. G., Smith, K. and Fiander, A. N. 2006. Recovery of human papillomavirus nucleic acids from liquid-based cytology media. Journal of Virological Methods 137(1), pp. 58-62. (10.1016/j.jviromet.2006.05.033)
• Hibbits, S. J., Hart, K. W., Rieck, G. C., Powell, N. G., Hauke, A. and Fiander, A. N. 2006. Human papillomavirus infection: an Anonymous Prevalence Study in South Wales, UK. British Journal of Cancer 95(2), pp. 226-32. (10.1038/sj.bjc.6603245)
• Ferreiro, J. A., Powell, N. G., Karabetsou, N., Mellor, J. and Waters, R. 2006. Roles for Gcn5p and Ada2p in transcription and nucleotide excision repair at the Saccharomyces cerevisiae MAET16 gene. Nucleic Acids Research 34(3), pp. 976-985. (10.1093/nar/gkj501)

2004

• Ferreiro, A., Powell, N. G., Karabetsou, N., Kent, N. A., Mellor, J. and Waters, R. 2004. Cbf1p modulates chromatin structure, transcription and repair at the Saccharomyces cerevisiae MET16 locus. Nucleic Acids Research 32(5), pp. 1617-1626. (10.1093/nar/gkh324)