Parinda Prapaiwongs

(she/her)

MNeuro

Overview

I work in Professor Meng Li’s Stem Cell Neurogenesis Group at the Neuroscience and Mental Health Innovation Institute. My research focuses on elucidating the cellular composition of human pluripotent stem cell (hPSC)-derived medium spiny neurons (MSNs) and the developing human striatum using single-cell RNA sequencing and bioinformatics analysis.

In addition, I am interested in the role of interneurons in MSN maturation. To explore this, we employ hPSC-derived three-dimensional organoids and assembloids, which serve as in vitro models to examine the cellular composition and development of MSN.

This research contributes to our understanding of striatal development and has implications for developing better strategies for cell therapies for neurodegenerative disorders affecting the striatum, such as Huntington's disease.