![Frances Rice](https://profiles-cardiff.imgix.net/attachments/2557?w=200&h=200&auto=format&crop=faces&fit=crop&q=90")
Professor Frances Rice
Professor of Developmental Psychopathology, Division of Psychological Medicine and Clinical Neurosciences
- Available for postgraduate supervision
Overview
I study the origins and development of depression and anxiety in young people. I am interested in identifying causal risk and protective factors that can be targeted as part of interventions to prevent and treat depression and anxiety in young people. I am also interested in the family and genetic influences on depression and anxiety, how these operate across development, and identifying ways of supporting families and children where a parent suffers from a common mental health problem. I am interested in the relationship between school and mental health, and in transition points such as the transition to secondary school and between adolescence and adult life. I use a range of research approaches including longitudinal prospective studies of families and young people and genetic epidemiology.
I am co-director of the Wolfson Centre for Young People’s Mental Health a £10 million research centre dedicated to understanding anxiety and depression in young people.
Publication
2024
- Dennison, C. A., Shakeshaft, A., Eyre, O., Tilling, K., Rice, F. and Thapar, A. 2024. Investigating the neurodevelopmental correlates of early adolescent-onset emotional problems. Journal of Affective Disorders 364, pp. 212-220. (10.1016/j.jad.2024.08.008)
- Tseliou, F. et al. 2024. Childhood correlates and young adult outcomes of trajectories of emotional problems from childhood to adolescence. Psychological Medicine 54(10), pp. 2504-2514. (10.1017/S0033291724000631)
- Padaigaitė‐Gulbinienė, E., Hammerton, G., Powell, V., Rice, F. and Collishaw, S. 2024. Modifiable protective factors for mental health resilience in the offspring of depressed parents: A high‐risk longitudinal cohort spanning adolescence and adulthood. JCPP Advances, article number: e12240. (10.1002/jcv2.12240)
- Donaldson, C., Hawkins, J., Rice, F. and Moore, G. 2024. Trajectories of mental health across the primary to secondary school transition. JCPP Advances (10.1002/jcv2.12244)
- Dennison, C. et al. 2024. Stratifying early-onset emotional disorders: using genetics to assess persistence in young people of European and South Asian ancestry. Journal of Child Psychology and Psychiatry 65(1), pp. 42-51. (10.1111/jcpp.13862)
- Bowman, S., Morris, T. T., Dickson, M., Rice, F., Howe, L. D. and Hughes, A. M. 2024. Maternal depressive symptoms and young people's higher education participation and choice of university: Evidence from a longitudinal cohort study. Journal of Affective Disorders 344, pp. 339-346. (10.1016/j.jad.2023.10.061)
- Padaigaitė-Gulbinienė, E., Hammerton, G., Powell, V., Rice, F. and Collishaw, S. 2024. Modifiable protective factors for mental health resilience in the offspring of depressed parents: a high-risk longitudinal cohort spanning adolescence and adulthood. Wiley Open Access.
2023
- Powell, V. et al. 2023. Following the children of depressed parents from childhood to adult life: a focus on mood and anxiety disorders. JCPP Advances 3(4), article number: e12182. (10.1002/jcv2.12182)
- Anthony, R. et al. 2023. Trends in adolescent emotional problems in Wales between 2013 and 2019: the contribution of peer relationships. Journal of Child Psychology and Psychiatry (10.1111/jcpp.13924)
- Weavers, B. et al. 2023. Characterising depression trajectories in young people at high familial risk of depression. Journal of Affective Disorders 337, pp. 66-74. (10.1016/j.jad.2023.05.063)
- Armitage, J. M. et al. 2023. Cross-cohort change in parent-reported emotional problem trajectories across childhood and adolescence in the UK. The Lancet Psychiatry 10(7), pp. 509-517. (10.1016/S2215-0366(23)00175-X)
- Armitage, J. M. et al. 2023. Validation of the Strengths and Difficulties Questionnaire (SDQ) emotional subscale in assessing depression and anxiety across development. PLoS ONE 18(7), article number: e0288882. (10.1371/journal.pone.0288882)
- Bevan-Jones, R. et al. 2023. Digital technologies to support adolescents with depression and anxiety. BJPsych Advances 29(4), pp. 239-253. (10.1192/bja.2022.3)
- Bevan-Jones, R. et al. 2023. Further development and feasibility randomised controlled trial of a digital programme for adolescent depression, MoodHwb: study protocol. BMJ Open 13(6), article number: e070369. (10.1136/bmjopen-2022-070369)
- Uher, R. et al. 2023. Developmental phenotypes of sequential comorbidity leading to major mood disorders. Biological Psychiatry 93(9), article number: Supp1. (10.1016/j.biopsych.2023.02.176)
- Zwicker, A. et al. 2023. Polygenic scores and onset of major mood or psychotic disorders among offspring of affected parents. The American Journal of Psychiatry 180(4), pp. 285-293. (10.1176/appi.ajp.20220476)
- Stephens, A. et al. 2023. Developing and validating a prediction model of adolescent major depressive disorder in the offspring of depressed parents. Journal of Child Psychology and Psychiatry 64(3), pp. 367-375. (10.1111/jcpp.13704)
- Lynham, A. J. et al. 2023. DRAGON-Data: A platform and protocol for integrating genomic and phenotypic data across large psychiatric cohorts. BJPsych Open 9(2), article number: e32. (10.1192/bjo.2022.636)
2022
- Rice, F. 2022. The intergenerational transmission of anxiety disorders and major depression. American Journal of Psychiatry 179(9), pp. 589-691. (10.1176/appi.ajp.20220570)
- Padaigaitė, E., Maruyama, J. M., Hammerton, G., Rice, F. and Collishaw, S. 2022. Mental health resilience in offspring of depressed parents: a systematic literature review protocol. Systematic Reviews 11(1), article number: 190. (10.1186/s13643-022-02056-6)
- Nazzari, S., Fearon, P., Rice, F., Molteni, M. and Frigerio, A. 2022. Maternal caregiving moderates the impact of antenatal maternal cortisol on infant stress regulation. Journal of Child Psychology and Psychiatry 63(8), pp. 871-880. (10.1111/jcpp.13532)
- Warne, N. et al. 2022. Collecting genetic samples and linked mental health data from adolescents in schools: protocol co-production and a mixed-methods pilot of feasibility and acceptability. BMJ Open 12(2), article number: e049283. (10.1136/bmjopen-2021-049283)
- Warne, N. and Rice, F. 2022. Links between depressive symptoms and the observer perspective for autobiographical memories and imagined events: a high familial risk study. Journal of Cognitive Psychology 34(1), pp. 82-97. (10.1080/20445911.2021.1922418)
2021
- Kwong, A. S. F., Morris, T. T., Pearson, R. M., Timpson, N. J., Rice, F., Stergiakouli, E. and Tilling, K. 2021. Polygenic risk for depression, anxiety and neuroticism are associated with the severity and rate of change in depressive symptoms across adolescence. Journal of Child Psychology and Psychiatry 62(12), pp. 1462-1474. (10.1111/jcpp.13422)
- Weavers, B. et al. 2021. The antecedents and outcomes of persistent and remitting adolescent depressive symptom trajectories: a longitudinal, population-based English study. The Lancet Psychiatry 8(12), pp. 1053-1061. (10.1016/S2215-0366(21)00281-9)
- Powell, V. et al. 2021. ADHD in adults with recurrent depression. Journal of Affective Disorders 295, pp. 1153-1160. (10.1016/j.jad.2021.09.010)
- Cadman, T. et al. 2021. The role of school enjoyment and connectedness in the association between depressive and externalising symptoms and academic attainment: Findings from a UK prospective cohort study. Journal of Affective Disorders 295, pp. 974-980. (10.1016/j.jad.2021.08.043)
- Brophy, S., Todd, C., Rahman, M. A., Kennedy, N. and Rice, F. 2021. Timing of parental depression on risk of child depression and poor educational outcomes: A population based routine data cohort study from Born in Wales, UK. PLoS ONE 16(11), article number: e0258966. (10.1371/journal.pone.0258966)
- Martin, J. et al. 2021. Examining sex differences in neurodevelopmental and psychiatric genetic risk in anxiety and depression. PLoS ONE 16(9), article number: e0248254. (10.1371/journal.pone.0248254)
- Riglin, L. et al. 2021. ADHD and depression: investigating a causal explanation. Psychological Medicine 51(11), pp. 1890-1897. (10.1017/S0033291720000665)
- Powell, V. et al. 2021. Investigating friendship difficulties in the pathway from ADHD to depressive symptoms. Can parent-child relationships compensate?. Research on Child and Adolescent Psychopathology 49, pp. 1031-1041. (10.1007/s10802-021-00798-w)
- Moore, G., Angel, L., Brown, R., van Godwin, J., Hallingberg, B. and Rice, F. 2021. Socio-economic status, mental health difficulties and feelings about transition to secondary school among 10-11 year olds in Wales: multi-level analysis of a cross sectional survey. Child Indicators Research 14, pp. 1597-1615. (10.1007/s12187-021-09815-2)
- Rice, F. et al. 2021. Pupil mental health, concerns and expectations about secondary school as predictors of adjustment across the transition to secondary school: A longitudinal multi-informant study. School Mental Health 13, pp. 279-298. (10.1007/s12310-021-09415-z)
- Powell, V., Martin, J., Thapar, A., Rice, F. and Anney, R. 2021. Investigating regions of shared genetic variation in attention deficit/hyperactivity disorder and major depressive disorder: a GWAS meta-analysis. Scientific Reports 11, article number: 7353. (10.1038/s41598-021-86802-1)
- Thapar, A. and Rice, F. 2021. Family-based designs that disentangle inherited factors from pre- and postnatal environmental exposures: in vitro fertilization, discordant sibling pairs, maternal versus paternal comparisons, and adoption designs. Cold Spring Harbor Perspectives in Medicine 11(3), article number: a038877. (10.1101/cshperspect.a038877)
- Hughes, A., Wade, K. H., Dickson, M., Rice, F., Davies, A., Davies, N. M. and Howe, L. D. 2021. Common health conditions in childhood and adolescence, school absence, and educational attainment: Mendelian randomization study. npj Science of Learning 6, article number: 1. (10.1038/s41539-020-00080-6)
2020
- Nazzari, S., Fearon, P., Rice, F., Ciceri, F., Molteni, M. and Frigerio, A. 2020. Neuroendocrine and immune markers of maternal stress during pregnancy and infant cognitive development. Developmental Psychobiology 62(8), pp. 1100-1110. (10.1002/dev.21967)
- Powell, V. et al. 2020. What explains the link between childhood ADHD and adolescent depression? Investigating the role of peer relationships and academic attainment. European Child and Adolescent Psychiatry 29, pp. 1581-1591. (10.1007/s00787-019-01463-w)
- Selous, C., Kelly-Irving, M., Maughan, B., Eyre, O., Rice, F. and Collishaw, S. 2020. Adverse childhood experiences and adult mood problems: evidence from a five-decade prospective birth cohort. Psychological Medicine 50(14), pp. 2444-2451. (10.1017/S003329171900271X)
- Harrison, S. et al. 2020. The causal effects of health conditions and risk factors on social and socioeconomic outcomes: mendelian randomization in UK biobank. International Journal of Epidemiology 49(5), pp. 1661-1691. (10.1093/ije/dyaa114)
- Nazzari, S., Fearon, P., Rice, F., Ciceri, F., Molteni, M. and Frigerio, A. 2020. The biological underpinnings of perinatal depressive symptoms: a multi-systems approach.. Journal of Affective Disorders 274, pp. 1004-1012. (10.1016/j.jad.2020.05.023)
- Argent, S. E., Kalebic, N., Rice, F. and Taylor, P. 2020. Offspring outcomes when a parent experiences one or more major psychiatric disorder(s): a clinical review. Evidence-Based Mental Health 23, pp. 113-121. (10.1136/ebmental-2019-300123)
- Bevan Jones, R. et al. 2020. Practitioner review: Co-design of digital mental health technologies with children and young people. Journal of Child Psychology and Psychiatry 61(8), pp. 928-940. (10.1111/jcpp.13258)
- Bevan-Jones, R. et al. 2020. A digital intervention for adolescent depression 'MoodHwb': mixed-methods feasibility evaluation. JMIR Mental Health 7(7), article number: e14536. (10.2196/14536)
- Sellers, R. et al. 2020. Using a cross-cohort comparison design to test the role of maternal smoking in pregnancy in child mental health and learning: evidence from two UK cohorts born four decades apart. International Journal of Epidemiology 49(2), pp. 390-399. (10.1093/ije/dyaa001)
- Warne, N., Caseras, X. and Rice, F. 2020. The cross-sectional and longitudinal relationship between overgeneral autobiographical memory and adolescent depression in a UK population-based cohort. Journal of Affective Disorders 266, pp. 621-625. (10.1016/j.jad.2020.02.011)
2019
- Ng-Knight, T., Shelton, K. H., Riglin, L., Frederickson, N., McManus, I. C. and Rice, F. 2019. 'Best friends forever'? Friendship stability across school transition and associations with mental health and educational attainment. British Journal of Educational Psychology 89(4), pp. 585-599. (10.1111/bjep.12246)
- Rice, F., Riglin, L., Thapar, A. K., Heron, J., Anney, R., O'Donovan, M. C. and Thapar, A. 2019. Characterizing developmental trajectories and the role of neuropsychiatric genetic risk variants in early-onset depression. JAMA Psychiatry 76(3), pp. 306-313. (10.1001/jamapsychiatry.2018.3338)
- Nazzari, S., Fearon, P., Rice, F., Dottori, N., Ciceri, F., Molteni, M. and Frigerio, A. 2019. Beyond the HPA-axis: Exploring maternal prenatal influences on birth outcomes and stress reactivity. Psychoneuroendocrinology 101, pp. 253-262. (10.1016/j.psyneuen.2018.11.018)
- Rice, F. et al. 2019. Adolescent and adult differences in major depression symptom profiles. Journal of Affective Disorders 243, pp. 175-181. (10.1016/j.jad.2018.09.015)
- Warne, N., Collishaw, S. and Rice, F. 2019. Examining the relationship between stressful life events and overgeneral autobiographical memory in adolescents at high familial risk of depression. Memory 27(3), pp. 314-327. (10.1080/09658211.2018.1508591)
2018
- Riglin, L. et al. 2018. The impact of schizophrenia and mood disorder risk alleles on emotional problems: investigating change from childhood to middle age. Psychological Medicine 48(13), pp. 2153-2158. (10.1017/S0033291717003634)
- Fraser, A., Cooper, M., Agha, S. S., Collishaw, S., Rice, F., Thapar, A. and Eyre, O. 2018. The presentation of depression symptoms in attention-deficit/hyperactivity disorder: comparing child and parent reports. Child and Adolescent Mental Health 23(3), pp. 243-250. (10.1111/camh.12253)
- Rice, F., Langley, K., Woodford, C., Davey Smith, G. and Thapar, A. 2018. Identifying the contribution of prenatal risk factors to offspring development and psychopathology: What designs to use and a critique of literature on maternal smoking and stress in pregnancy. Development and Psychopathology 30(3), pp. 1107-1128. (10.1017/S0954579418000421)
- Rahman, M. A. et al. 2018. School achievement as a predictor of depression and self-harm in adolescence: linked education and health record study. British Journal of Psychiatry 212(4), pp. 215-221. (10.1192/bjp.2017.69)
- Bevan Jones, R. et al. 2018. A web-based psychoeducational intervention for adolescent depression: design and development of MoodHwb. JMIR Mental Health 5(1), article number: e13. (10.2196/mental.8894)
- Ng-Knight, T., Shelton, K. H., Frederickson, N., McManus, I. C. and Rice, F. 2018. Maternal depressive symptoms and adolescent academic attainment: Testing pathways via parenting and self-control. Journal of Adolescence 62, pp. 61-69. (10.1016/j.adolescence.2017.11.003)
2017
- Rice, F. et al. 2017. Antecedents of new-onset major depressive disorder in children and adolescents at high familial risk. JAMA Psychiatry 74(2), pp. 153-160. (10.1001/jamapsychiatry.2016.3140)
- Rice, F., Eyre, O., Riglin, L. and Potter, R. 2017. Adolescent depression and the treatment gap. The Lancet Psychiatry 4(2), pp. 86-87. (10.1016/S2215-0366(17)30004-4)
2016
- Thapar, A. et al. 2016. Identifying key parent-reported symptoms for detecting depression in high risk adolescents. Psychiatry Research 242, pp. 210-217. (10.1016/j.psychres.2016.05.025)
- Davidovich, S., Collishaw, S., Thapar, A. K., Harold, G., Thapar, A. and Rice, F. 2016. Do better executive functions buffer the effect of current parental depression on adolescent depressive symptoms?. Journal of Affective Disorders 199, pp. 54-64. (10.1016/j.jad.2016.03.049)
- Ng-Knight, T., Shelton, K. H., Riglin, L., McManus, I., Frederickson, N. and Rice, F. 2016. A longitudinal study of self-control at the transition to secondary school: Considering the role of pubertal status and parenting. Journal of Adolescence 50, pp. 44-55. (10.1016/j.adolescence.2016.04.006)
- Neal, S., Rice, F., Ng-Knight, T., Riglin, L. and Frederickson, N. 2016. Exploring the longitudinal association between interventions to support the transition to secondary school and child anxiety. Journal of Adolescence 50, pp. 31-43. (10.1016/j.adolescence.2016.04.003)
- Riglin, L., Thapar, A., Shelton, K. H., Langley, K., Frederickson, N. and Rice, F. 2016. Profiling depression in childhood and adolescence: the role of conduct problems. Journal of Child Psychology and Psychiatry 57(4), pp. 481-490. (10.1111/jcpp.12465)
- Riglin, L. et al. 2016. Higher cognitive ability buffers stress-related depressive symptoms in adolescent girls. Development and Psychopathology 28(1), pp. 97-109. (10.1017/S0954579415000310)
- Sellers, R. et al. 2016. Examining whether offspring psychopathology influences illness course in mothers with recurrent depression using a high-risk longitudinal sample. Journal of Abnormal Psychology 125(2), pp. 256-266. (10.1037/abn0000080)
- Collishaw, S. et al. 2016. Mental health resilience in the adolescent offspring of parents with depression: a prospective longitudinal study. Lancet Psychiatry 3(1), pp. 49-57. (10.1016/S2215-0366(15)00358-2)
2015
- McManus, I. C., Ng-Knight, T., Riglin, L., Frederickson, N., Shelton, K. H. and Rice, F. 2015. Doctor, builder, soldier, lawyer, teacher, dancer, shopkeeper, vet: exploratory study of which eleven-year olds would like to become a doctor. BMC Psychology 3(1), article number: 38. (10.1186/s40359-015-0094-z)
- Rice, F., Rawal, A., Riglin, L., Lewis, G., Lewis, G. and Dunsmuir, S. 2015. Examining reward-seeking, negative self-beliefs and over-general autobiographical memory as mechanisms of change in classroom prevention programs for adolescent depression. Journal of Affective Disorders 186, pp. 320-327. (10.1016/j.jad.2015.07.019)
- Mars, B. et al. 2015. Longitudinal symptom course in adults with recurrent depression: Impact on impairment and risk of psychopathology in offspring. Journal of Affective Disorders 182, pp. 32-38. (10.1016/j.jad.2015.04.018)
- Kilford, E. J., Foulkes, L., Potter, R., Collishaw, S., Thapar, A. and Rice, F. 2015. Affective bias and current, past and future adolescent depression: a familial high risk study. Journal of Affective Disorders 174, pp. 265-271. (10.1016/j.jad.2014.11.046)
2014
- Rawal, A., Riglin, L., Ng-Knight, T., Collishaw, S., Thapar, A. and Rice, F. 2014. A longitudinal high-risk study of adolescent anxiety, depression and parent-severity on the developmental course of risk-adjustment. Journal of Child Psychology and Psychiatry 55(11), pp. 1270-1278. (10.1111/jcpp.12279)
- Eyre, O. et al. 2014. Reported child awareness of parental depression. Psychiatric Bulletin 38(3), pp. 122-127. (10.1192/pb.bp.113.044198)
- Riglin, L., Petrides, K., Frederickson, N. and Rice, F. 2014. The relationship between emotional problems and subsequent school attainment: A meta-analysis. Journal of Adolescence 37(4), pp. 335-346. (10.1016/j.adolescence.2014.02.010)
- Rice, F. 2014. Prospective and mutual influences of reward processing and emotional disorders in a longitudinal study of the adolescent offspring of depressed parents: the EPAD Cohort. Biological Psychiatry 75(9), pp. 195S. (10.1016/j.biopsych.2014.03.015)
- Thapar, A. K. et al. 2014. Detecting recurrent major depressive disorder within primary care rapidly and reliably using short questionnaire measures. British Journal of General Practice (BJGP) 64(618), pp. e31-7. (10.3399/bjgp14X676438)
2013
- Lewis, K. J. et al. 2013. The Depression impairment scale for parents (DISP): A new scale for the measurement of impairment in depressed parents. Psychiatry Research 210(3), pp. 1184-1190. (10.1016/j.psychres.2013.08.001)
- Rawal, A., Collishaw, S., Thapar, A. and Rice, F. 2013. A direct method of assessing underlying cognitive risk for adolescent depression. Journal of Abnormal Child Psychology 41(8), pp. 1279-1288. (10.1007/s10802-013-9760-x)
- Mars, B. et al. 2013. Specific parental depression symptoms as risk markers for new-onset depression in high-risk offspring. The Journal of Clinical Psychiatry 74(9), pp. 925-931. (10.4088/JCP.12m08152)
- Riglin, L., Frederickson, N., Shelton, K. H. and Rice, F. 2013. A longitudinal study of psychological functioning and academic attainment at the transition to secondary school. Journal of Adolescence 36(3), pp. 507-517. (10.1016/j.adolescence.2013.03.002)
- Rice, F., Lewis, G., Harold, G. T. and Thapar, A. 2013. Examining the role of passive gene-environment correlation in childhood depression using a novel genetically sensitive design. Development and Psychopathology 25(1), pp. 37-50. (10.1017/S0954579412000880)
- Rawal, A., Collishaw, S., Thapar, A. and Rice, F. 2013. 'The risks of playing it safe': a prospective longitudinal study of response to reward in the adolescent offspring of depressed parents. Psychological Medicine 43(1), pp. 27-38. (10.1017/S0033291712001158)
2012
- Lewis, K. J. et al. 2012. Do parents know best? Parent-reported vs. child-reported depression symptoms as predictors of future child mood disorder in a high-risk sample. Journal of Affective Disorders 141(2-3), pp. 233-236. (10.1016/j.jad.2012.03.008)
- Harold, G. T., Elam, K. K., Lewis, G., Rice, F. and Thapar, A. 2012. Interparental conflict, parent psychopathology, hostile parenting, and child antisocial behavior: Examining the role of maternal versus paternal influences using a novel genetically sensitive research design. Development and Psychopathology 24(4), pp. 1283-1295. (10.1017/S0954579412000703)
- Sellers, R. et al. 2012. Risk of psychopathology in adolescent offspring of mothers with psychopathology and recurrent depression. British Journal of Psychiatry 202(2), pp. 108-114. (10.1192/bjp.bp.111.104984)
- Potter, R. et al. 2012. Missed opportunities: mental disorder in children of parents with depression. British Journal of General Practice (BJGP) 62(600), pp. e487-e493. (10.3399/bjgp12X652355)
- Rawal, A. and Rice, F. 2012. Examining overgeneral autobiographical memory as a risk factor for adolescent depression. Journal of the American Academy of Child & Adolescent Psychiatry 51(5), pp. 518-527. (10.1016/j.jaac.2012.02.025)
- Lewis, G., Collishaw, S., Harold, G. T., Rice, F. and Thapar, A. 2012. Maternal depression and child and adolescent depression symptoms: an exploratory test for moderation by CRHR1, FKBP5 and NR3C1 gene variants. Behavior Genetics 42(1), pp. 121-132. (10.1007/s10519-011-9482-1)
- Mars, B. et al. 2012. Offspring of parents with recurrent depression: which features of parent depression index risk for offspring psychopathology?. Journal of affective disorders 136(1-2), pp. 44-53. (10.1016/j.jad.2011.09.002)
- Rawal, A. and Rice, F. 2012. A longitudinal study of processes predicting the specificity of autobiographical memory in the adolescent offspring of depressed parents. Memory 20(5), pp. 518-526. (10.1080/09658211.2012.683011)
2011
- Shelton, K. H., Collishaw, S., Rice, F., Harold, G. T. and Thapar, A. 2011. Using a genetically informative design to examine the relationship between breastfeeding and childhood conduct problems. European Child and Adolescent Psychiatry 20(11-12), pp. 571-579. (10.1007/s00787-011-0224-y)
- Harold, G. T., Rice, F., Hay, D. F., Boivin, J., van den Bree, M. B. and Thapar, A. 2011. Familial transmission of depression and antisocial behavior symptoms: Disentangling the contribution of inherited and environmental factors and testing the mediating role of parenting. Psychological Medicine 41(6), pp. 1175-1185. (10.1017/S0033291710001753)
- Rice, F., Frederickson, N. and Seymour, J. 2011. Assessing pupil concerns about transition to secondary school. British Journal of Educational Psychology 81(2), pp. 244-263. (10.1348/000709910X519333)
- Lewis, G., Rice, F., Harold, G. T., Collishaw, S. and Thapar, A. 2011. Investigating environmental links between parent depression and child depressive/anxiety symptoms using an assisted conception design. Journal of the American Academy of Child & Adolescent Psychiatry 50(5), pp. 451-459. (10.1016/j.jaac.2011.01.015)
2010
- Rice, F. 2010. Genetics of childhood and adolescent depression: insights into etiological heterogeneity and challenges for future genomic research. Genome Medicine 2, article number: 68. (10.1186/gm189)
- Thapar, A. et al. 2010. Response to: testing the association between smoking in pregnancy and attention-deficit/hyperactivity disorder in a novel design [Letter]. Biological psychiatry 68(4), pp. e13-e14. (10.1016/j.biopsych.2010.01.032)
- Rice, F., Harold, G. T., Boivin, J., van den Bree, M. B., Hay, D. F. and Thapar, A. 2010. The links between prenatal stress and offspring development and psychopathology: Disentangling environmental and inherited influences. Psychological Medicine 40(2), pp. 335-345. (10.1017/S0033291709005911)
- Rice, F. and Thapar, A. 2010. Estimating the relative contributions of maternal genetic, paternal genetic and intrauterine factors to offspring birth weight and head circumference. Early Human Development 86(7), pp. 425-432. (10.1016/j.earlhumdev.2010.05.021)
2009
- Fowler, T. A. et al. 2009. Psychopathy trait scores in adolescents with childhood ADHD: the contribution of genotypes affecting MAOA, 5HTT and COMT activity. Psychiatric Genetics 19(6), pp. 312-319. (10.1097/YPG.0b013e3283328df4)
- Thapar, A. et al. 2009. Prenatal smoking might not cause Attention-Deficit/Hyperactivity Disorder: Evidence from a novel design. Biological Psychiatry 66(8), pp. 722-727. (10.1016/j.biopsych.2009.05.032)
- Shelton, K. H., Boivin, J., Hay, D. F., van den Bree, M. B., Rice, F., Harold, G. T. and Thapar, A. 2009. Examining differences in psychological adjustment problems among children conceived by assisted reproductive technologies. International Journal of Behavioral Development 33(5), pp. 385-392. (10.1177/0165025409338444)
- Boivin, J., Rice, F., Hay, D. F., Harold, G. T., Lewis, A., van den Bree, M. B. and Thapar, A. 2009. Associations between maternal older age, family environment and parent and child wellbeing in families using assisted reproductive techniques to conceive. Social Science & Medicine 68(11), pp. 1948-1955. (10.1016/j.socscimed.2009.02.036)
- Rice, F. 2009. The genetics of depression in childhood and adolescence. Current Psychiatry Reports 11(2), pp. 167-173. (10.1007/s11920-009-0026-9)
- Rice, F. and Thapar, A. 2009. Depression and anxiety in childhood and adolescence: developmental pathways, genes and environment. In: Kim, Y. ed. Handbook of Behavior Genetics. New York: Springer, pp. 379-396., (10.1007/978-0-387-76727-7_26)
- Rice, F., Harold, G. T., Boivin, J., Hay, D. F., van den Bree, M. B. and Thapar, A. 2009. Disentangling prenatal and inherited influences in humans with an experimental design. Proceedings of the National Academy of Sciences of the United States of America 106(7), pp. 2464-2467. (10.1073/pnas.0808798106)
- Fowler, T. A. et al. 2009. Psychopathy traits in adolescents with childhood attention-deficit hyperactivity disorder. British Journal of Psychiatry 194(1), pp. 62-67. (10.1192/bjp.bp.107.046870)
2008
- Shelton, K. H., Harold, G. T., Fowler, T. A., Rice, F., Neale, M. C., Thapar, A. and van den Bree, M. B. 2008. Parent-Child Relations, Conduct Problems and Cigarette Use in Adolescence: Examining the Role of Genetic and Environmental Factors on Patterns of Behavior. Journal of Youth and Adolescence 37(10), pp. 1216-1228. (10.1007/s10964-007-9254-7)
- Langley, K. et al. 2008. Testing for gene × environment interaction effects in attention deficit hyperactivity disorder and associated antisocial behavior. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 147B(1), pp. 49-53. (10.1002/ajmg.b.30571)
- Harold, G. T., Shelton, K. H., Rice, F., Boivin, J., Hay, D. F., van den Bree, M. B. and Thapar, A. 2008. Disentangling genetic and environmental influences on children’s development: introducing a novel methodology. Acta Psychologica Sinica 40(10), pp. 1124-1134.
2007
- Rice, F. et al. 2007. Genetic and environmental transmission of anxiety and depression in families using a novel design [Abstract]. Behavior Genetics 37(6), pp. 788-788. (10.1007/s10519-007-9169-9)
- Thapar, A., Harold, G. T., Rice, F., Langley, K. and O'Donovan, M. C. 2007. The contribution of gene-environment interaction to psychopathology. Development and Psychopathology 19(4), pp. 989-1004. (10.1017/S0954579407000491)
- Rice, F., Lifford, K. J., Thomas, H. V. and Thapar, A. 2007. Mental health and functional outcomes of maternal and adolescent reports of adolescent depressive symptoms. Journal of the American Academy of Child & Adolescent Psychiatry 46(9), pp. 1162-1170. (10.1097/chi.0b013e3180cc255f)
- Rice, F., Jones, I. R. and Thapar, A. 2007. Impact of gestational distress and growth retardation on emotional problems in offspring - Reply [Letter]. Acta Psychiatrica Scandinavica 116(2), pp. 154-155. (10.1111/j.1600-0447.2007.01042.x)
- Fowler, T. A. et al. 2007. Exploring the relationship between genetic and environmental influences on initiation and progression of substance use. Addiction 102(3), pp. 413-422. (10.1111/j.1360-0443.2006.01694.x)
- Shelton, K. H., Lifford, K., Fowler, T., Rice, F., Harold, G. T., Thapar, A. and van den Bree, M. B. 2007. The association between conduct problems and the initiation and progression of marijuana use during adolescence: A genetic analysis across time. Behavior Genetics 37(2), pp. 314-325. (10.1007/s10519-006-9124-1)
- Rice, F., Jones, I. R. and Thapar, A. 2007. The impact of gestational stress and prenatal growth on emotional problems in offspring: a review [Review]. Acta Psychiatrica Scandinavica 115(3), pp. 171-183. (10.1111/j.1600-0447.2006.00895.x)
- van den Bree, M. B. et al. 2007. The Cardiff Study of All Wales and North West of England Twins (CaStANET): A longitudinal research program of child and adolescent development. Twin Research and Human Genetics 10(1), pp. 13-23. (10.1375/twin.10.1.13)
- Thapar, A. et al. 2007. Do intrauterine or genetic influences explain the foetal origins of chronic disease? A novel experimental method for disentangling effects. BMC Medical Research Methodology 7(1), pp. 25-32. (10.1186/1471-2288-7-25)
- Fowler, T. et al. 2007. Genetic and environmental influences on the relationship between peer alcohol use and own alcohol use in adolescents. Addiction 102(6), pp. 894-903. (10.1111/j.1360-0443.2007.01824.x)
- Rice, F. et al. 2007. Agreement between maternal report and antenatal records for a range of pre and peri-natal factors: The influence of maternal and child characteristics. Early Human Development 83(8), pp. 497-504. (10.1016/j.earlhumdev.2006.09.015)
- Thapar, A. et al. 2007. Promoting Measured Genes and Measured Environments: On the Importance of Careful Statistical Analyses and Biological Relevance—Reply [Letter]. Archives of General Psychiatry 64(3), pp. 378-379. (10.1001/archpsyc.64.3.378-b)
2006
- Thapar, A. and Rice, F. 2006. Twin studies in pediatric depression. Child and Adolescent Psychiatric Clinics of North America 15(4), pp. 869-81. (10.1016/j.chc.2006.05.007)
- Rice, F., Harold, G. T. and Thapar, A. 2006. The effect of birth-weight with genetic susceptibility on depressive symptoms in childhood and adolescence. European Child & Adolescent Psychiatry 15(7), pp. 383-391. (10.1007/s00787-006-0545-4)
- Fowler, T. A., Rice, F., Thapar, A. and Farmer, A. 2006. Relationship between disabling fatigue and depression in children: Genetic study. British Journal of Psychiatry 189(3), pp. 247-253. (10.1192/bjp.bp.105.011379)
- Rice, F., Harold, G. T., Shelton, K. H. and Thapar, A. 2006. Family conflict interacts with genetic liability in predicting childhood and adolescent depression. Journal of the American Academy of Child and Adolescent Psychiatry 45(7), pp. 841-848. (10.1097/01.chi.0000219834.08602.44)
2005
- Langley, K., Rice, F., van den Bree, M. B. and Thapar, A. 2005. Maternal smoking during pregnancy as an environmental risk factor for attention deficit hyperactivity disorder behaviour. A review.. Minerva Pediatrica 57(6), pp. 359-371.
- Thapar, A. et al. 2005. Catechol O-methyltransferase gene variant and birth weight predict early-onset antisocial behavior in children with attention-deficit/hyperactivity disorder. Archives of General Psychiatry 62(11), pp. 1275-1278. (10.1001/archpsyc.62.11.1275)
- Rice, F., Harold, G. T. and Thapar, A. 2005. The Link between depression in mothers and offspring: an extended twin analysis. Behavior Genetics 35(5), pp. 565-577. (10.1007/s10519-005-5432-0)
- Goody, A. J., Rice, F., Boivin, J., Harold, G. T., Hay, D. F. and Thapar, A. 2005. Twins born following fertility treatment: implications for quantitative genetic studies. Twin Research and Human Genetics 8(4), pp. 337-345. (10.1375/twin.8.4.337)
- Holmans, P. A. et al. 2005. Genome screen for loci influencing age at onset and rate of decline in late onset Alzheimer's disease. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 135B(1), pp. 24-32. (10.1002/ajmg.b.30114)
2004
- Rice, F., van den Bree, M. B. and Thapar, A. 2004. A population-based study of anxiety as a precursor for depression in childhood and adolescence. BMC Psychiatry 4, article number: 43. (10.1186/1471-244X-4-43)
- Rice, F., Goody, A. J., Boivin, J., Hay, D. F., Harold, G. T. and Thapar, A. 2004. A novel method for disentangling the effects of genes, intrauterine and environmental risk factors [Abstract]. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 130B(1), pp. 116-117. (10.1002/ajmg.b.30101)
2003
- Thapar, A., Boivin, J., Harold, G. T., Hay, D. F., Rice, F. and Goody, A. J. 2003. A novel method for disentangling the effects of genes, intrauterine, and environmental risk factors [Abstract]. Behavior Genetics 33(6), pp. 721-721. (10.1023/A:1026187215665)
- Thapar, A. et al. 2003. Maternal smoking during pregnancy and attention deficit hyperactivity disorder symptoms in offspring. American Journal of Psychiatry 160(11), pp. 1985-1989. (10.1176/appi.ajp.160.11.1985)
- Rice, F., Fowler, T., Scourfield, J. and Thapar, A. 2003. Anxiety and depression in childhood and adolescence: Developmental pathways, genes, and environment. Behavior Genetics 33(6), pp. 715-715.
- Rice, F., Harold, G. T. and Thapar, A. 2003. The transmission of depressive symptoms from mother to child: Genetic and environmental pathways. Behavior Genetics 33(6), pp. 716-716.
- Scourfield, J., Rice, F., Thapar, A., Harold, G. T., Martin, N. and McGuffin, P. 2003. Depressive symptoms in children and adolescents: Changing etiological influences with development. Behavior Genetics 33(6), pp. 718-719.
- Thapar, A. et al. 2003. Maternal smoking in pregnancy and attention deficit hyperactivity disorder symptoms in offspring. Behavior Genetics 33(6), pp. 720-721.
- Rice, F., Harold, G. T. and Thapar, A. 2003. Negative life events as an account of age-related differences in the genetic aetiology of depression in childhood and adolescence. Journal of Child Psychology and Psychiatry 44(7), pp. 977-987. (10.1111/1469-7610.00182)
- Scourfield, J., Rice, F., Thapar, A., Harold, G. T., Martin, N. and McGuffin, P. 2003. Depressive symptoms in children and adolescents: changing aetiological influences with development. Journal of Child Psychology and Psychiatry 44(7), pp. 968-976. (10.1111/1469-7610.00181)
- Rice, F., Abraham, R., Rudrasingham, V., Owen, M. J. and Williams, J. 2003. Memory for new information as a cognitive marker of liability to Alzheimer's disease in a high risk group: a research note. International Journal of Geriatric Psychiatry 18(2), pp. 155-160. (10.1002/gps.808)
2002
- Rice, F., Harold, G. T. and Thapar, A. 2002. Assessing the effects of age, sex and shared environment on the genetic aetiology of depression in childhood and adolescence. Journal of Child Psychology and Psychiatry 43(8), pp. 1039-1051. (10.1111/1469-7610.00231)
- Myers, A. et al. 2002. Full genome screen for Alzheimer disease: Stage II analysis. American Journal Of Medical Genetics Part A 114(2), pp. 235-244. (10.1002/ajmg.10183)
- Rice, F., Harold, G. T. and Thapar, A. 2002. The genetic aetiology of childhood depression: a review. Journal of Child Psychology and Psychiatry 43(1), pp. 65-79. (10.1111/1469-7610.00004)
2001
- Rice, F., Harold, G. T. and Thapar, A. 2001. Extreme depressive symptoms in children and adolescents. Behavior Genetics 31(5), pp. 467-467., article number: PMID: 15641870.
2000
- Myers, A. et al. 2000. Susceptibility locus for Alzheimer's disease on chromosome 10. Science 290(5500), pp. 2304-2305. (10.1126/science.290.5500.2304)
- Tunstall, N. et al. 2000. Familial influence on variation in age of onset and behavioural phenotype in Alzheimer's disease. British Journal of Psychiatry 176, pp. 156-159. (10.1192/bjp.176.2.156)
1999
- Rudrasingham, V. et al. 1999. Alpha-2 macroglobulin gene and Alzheimer disease. Nature Genetics 22(1), pp. 17-19. (10.1038/8726)
- Wavrant-DeVrieze, F. et al. 1999. No association between the alpha-2 macroglobulin I1000V polymorphism and Alzheimer's disease. Neuroscience Letters 262(2), pp. 137-139. (10.1016/S0304-3940(99)00035-X)
Articles
- Dennison, C. A., Shakeshaft, A., Eyre, O., Tilling, K., Rice, F. and Thapar, A. 2024. Investigating the neurodevelopmental correlates of early adolescent-onset emotional problems. Journal of Affective Disorders 364, pp. 212-220. (10.1016/j.jad.2024.08.008)
- Tseliou, F. et al. 2024. Childhood correlates and young adult outcomes of trajectories of emotional problems from childhood to adolescence. Psychological Medicine 54(10), pp. 2504-2514. (10.1017/S0033291724000631)
- Padaigaitė‐Gulbinienė, E., Hammerton, G., Powell, V., Rice, F. and Collishaw, S. 2024. Modifiable protective factors for mental health resilience in the offspring of depressed parents: A high‐risk longitudinal cohort spanning adolescence and adulthood. JCPP Advances, article number: e12240. (10.1002/jcv2.12240)
- Donaldson, C., Hawkins, J., Rice, F. and Moore, G. 2024. Trajectories of mental health across the primary to secondary school transition. JCPP Advances (10.1002/jcv2.12244)
- Dennison, C. et al. 2024. Stratifying early-onset emotional disorders: using genetics to assess persistence in young people of European and South Asian ancestry. Journal of Child Psychology and Psychiatry 65(1), pp. 42-51. (10.1111/jcpp.13862)
- Bowman, S., Morris, T. T., Dickson, M., Rice, F., Howe, L. D. and Hughes, A. M. 2024. Maternal depressive symptoms and young people's higher education participation and choice of university: Evidence from a longitudinal cohort study. Journal of Affective Disorders 344, pp. 339-346. (10.1016/j.jad.2023.10.061)
- Powell, V. et al. 2023. Following the children of depressed parents from childhood to adult life: a focus on mood and anxiety disorders. JCPP Advances 3(4), article number: e12182. (10.1002/jcv2.12182)
- Anthony, R. et al. 2023. Trends in adolescent emotional problems in Wales between 2013 and 2019: the contribution of peer relationships. Journal of Child Psychology and Psychiatry (10.1111/jcpp.13924)
- Weavers, B. et al. 2023. Characterising depression trajectories in young people at high familial risk of depression. Journal of Affective Disorders 337, pp. 66-74. (10.1016/j.jad.2023.05.063)
- Armitage, J. M. et al. 2023. Cross-cohort change in parent-reported emotional problem trajectories across childhood and adolescence in the UK. The Lancet Psychiatry 10(7), pp. 509-517. (10.1016/S2215-0366(23)00175-X)
- Armitage, J. M. et al. 2023. Validation of the Strengths and Difficulties Questionnaire (SDQ) emotional subscale in assessing depression and anxiety across development. PLoS ONE 18(7), article number: e0288882. (10.1371/journal.pone.0288882)
- Bevan-Jones, R. et al. 2023. Digital technologies to support adolescents with depression and anxiety. BJPsych Advances 29(4), pp. 239-253. (10.1192/bja.2022.3)
- Bevan-Jones, R. et al. 2023. Further development and feasibility randomised controlled trial of a digital programme for adolescent depression, MoodHwb: study protocol. BMJ Open 13(6), article number: e070369. (10.1136/bmjopen-2022-070369)
- Uher, R. et al. 2023. Developmental phenotypes of sequential comorbidity leading to major mood disorders. Biological Psychiatry 93(9), article number: Supp1. (10.1016/j.biopsych.2023.02.176)
- Zwicker, A. et al. 2023. Polygenic scores and onset of major mood or psychotic disorders among offspring of affected parents. The American Journal of Psychiatry 180(4), pp. 285-293. (10.1176/appi.ajp.20220476)
- Stephens, A. et al. 2023. Developing and validating a prediction model of adolescent major depressive disorder in the offspring of depressed parents. Journal of Child Psychology and Psychiatry 64(3), pp. 367-375. (10.1111/jcpp.13704)
- Lynham, A. J. et al. 2023. DRAGON-Data: A platform and protocol for integrating genomic and phenotypic data across large psychiatric cohorts. BJPsych Open 9(2), article number: e32. (10.1192/bjo.2022.636)
- Rice, F. 2022. The intergenerational transmission of anxiety disorders and major depression. American Journal of Psychiatry 179(9), pp. 589-691. (10.1176/appi.ajp.20220570)
- Padaigaitė, E., Maruyama, J. M., Hammerton, G., Rice, F. and Collishaw, S. 2022. Mental health resilience in offspring of depressed parents: a systematic literature review protocol. Systematic Reviews 11(1), article number: 190. (10.1186/s13643-022-02056-6)
- Nazzari, S., Fearon, P., Rice, F., Molteni, M. and Frigerio, A. 2022. Maternal caregiving moderates the impact of antenatal maternal cortisol on infant stress regulation. Journal of Child Psychology and Psychiatry 63(8), pp. 871-880. (10.1111/jcpp.13532)
- Warne, N. et al. 2022. Collecting genetic samples and linked mental health data from adolescents in schools: protocol co-production and a mixed-methods pilot of feasibility and acceptability. BMJ Open 12(2), article number: e049283. (10.1136/bmjopen-2021-049283)
- Warne, N. and Rice, F. 2022. Links between depressive symptoms and the observer perspective for autobiographical memories and imagined events: a high familial risk study. Journal of Cognitive Psychology 34(1), pp. 82-97. (10.1080/20445911.2021.1922418)
- Kwong, A. S. F., Morris, T. T., Pearson, R. M., Timpson, N. J., Rice, F., Stergiakouli, E. and Tilling, K. 2021. Polygenic risk for depression, anxiety and neuroticism are associated with the severity and rate of change in depressive symptoms across adolescence. Journal of Child Psychology and Psychiatry 62(12), pp. 1462-1474. (10.1111/jcpp.13422)
- Weavers, B. et al. 2021. The antecedents and outcomes of persistent and remitting adolescent depressive symptom trajectories: a longitudinal, population-based English study. The Lancet Psychiatry 8(12), pp. 1053-1061. (10.1016/S2215-0366(21)00281-9)
- Powell, V. et al. 2021. ADHD in adults with recurrent depression. Journal of Affective Disorders 295, pp. 1153-1160. (10.1016/j.jad.2021.09.010)
- Cadman, T. et al. 2021. The role of school enjoyment and connectedness in the association between depressive and externalising symptoms and academic attainment: Findings from a UK prospective cohort study. Journal of Affective Disorders 295, pp. 974-980. (10.1016/j.jad.2021.08.043)
- Brophy, S., Todd, C., Rahman, M. A., Kennedy, N. and Rice, F. 2021. Timing of parental depression on risk of child depression and poor educational outcomes: A population based routine data cohort study from Born in Wales, UK. PLoS ONE 16(11), article number: e0258966. (10.1371/journal.pone.0258966)
- Martin, J. et al. 2021. Examining sex differences in neurodevelopmental and psychiatric genetic risk in anxiety and depression. PLoS ONE 16(9), article number: e0248254. (10.1371/journal.pone.0248254)
- Riglin, L. et al. 2021. ADHD and depression: investigating a causal explanation. Psychological Medicine 51(11), pp. 1890-1897. (10.1017/S0033291720000665)
- Powell, V. et al. 2021. Investigating friendship difficulties in the pathway from ADHD to depressive symptoms. Can parent-child relationships compensate?. Research on Child and Adolescent Psychopathology 49, pp. 1031-1041. (10.1007/s10802-021-00798-w)
- Moore, G., Angel, L., Brown, R., van Godwin, J., Hallingberg, B. and Rice, F. 2021. Socio-economic status, mental health difficulties and feelings about transition to secondary school among 10-11 year olds in Wales: multi-level analysis of a cross sectional survey. Child Indicators Research 14, pp. 1597-1615. (10.1007/s12187-021-09815-2)
- Rice, F. et al. 2021. Pupil mental health, concerns and expectations about secondary school as predictors of adjustment across the transition to secondary school: A longitudinal multi-informant study. School Mental Health 13, pp. 279-298. (10.1007/s12310-021-09415-z)
- Powell, V., Martin, J., Thapar, A., Rice, F. and Anney, R. 2021. Investigating regions of shared genetic variation in attention deficit/hyperactivity disorder and major depressive disorder: a GWAS meta-analysis. Scientific Reports 11, article number: 7353. (10.1038/s41598-021-86802-1)
- Thapar, A. and Rice, F. 2021. Family-based designs that disentangle inherited factors from pre- and postnatal environmental exposures: in vitro fertilization, discordant sibling pairs, maternal versus paternal comparisons, and adoption designs. Cold Spring Harbor Perspectives in Medicine 11(3), article number: a038877. (10.1101/cshperspect.a038877)
- Hughes, A., Wade, K. H., Dickson, M., Rice, F., Davies, A., Davies, N. M. and Howe, L. D. 2021. Common health conditions in childhood and adolescence, school absence, and educational attainment: Mendelian randomization study. npj Science of Learning 6, article number: 1. (10.1038/s41539-020-00080-6)
- Nazzari, S., Fearon, P., Rice, F., Ciceri, F., Molteni, M. and Frigerio, A. 2020. Neuroendocrine and immune markers of maternal stress during pregnancy and infant cognitive development. Developmental Psychobiology 62(8), pp. 1100-1110. (10.1002/dev.21967)
- Powell, V. et al. 2020. What explains the link between childhood ADHD and adolescent depression? Investigating the role of peer relationships and academic attainment. European Child and Adolescent Psychiatry 29, pp. 1581-1591. (10.1007/s00787-019-01463-w)
- Selous, C., Kelly-Irving, M., Maughan, B., Eyre, O., Rice, F. and Collishaw, S. 2020. Adverse childhood experiences and adult mood problems: evidence from a five-decade prospective birth cohort. Psychological Medicine 50(14), pp. 2444-2451. (10.1017/S003329171900271X)
- Harrison, S. et al. 2020. The causal effects of health conditions and risk factors on social and socioeconomic outcomes: mendelian randomization in UK biobank. International Journal of Epidemiology 49(5), pp. 1661-1691. (10.1093/ije/dyaa114)
- Nazzari, S., Fearon, P., Rice, F., Ciceri, F., Molteni, M. and Frigerio, A. 2020. The biological underpinnings of perinatal depressive symptoms: a multi-systems approach.. Journal of Affective Disorders 274, pp. 1004-1012. (10.1016/j.jad.2020.05.023)
- Argent, S. E., Kalebic, N., Rice, F. and Taylor, P. 2020. Offspring outcomes when a parent experiences one or more major psychiatric disorder(s): a clinical review. Evidence-Based Mental Health 23, pp. 113-121. (10.1136/ebmental-2019-300123)
- Bevan Jones, R. et al. 2020. Practitioner review: Co-design of digital mental health technologies with children and young people. Journal of Child Psychology and Psychiatry 61(8), pp. 928-940. (10.1111/jcpp.13258)
- Bevan-Jones, R. et al. 2020. A digital intervention for adolescent depression 'MoodHwb': mixed-methods feasibility evaluation. JMIR Mental Health 7(7), article number: e14536. (10.2196/14536)
- Sellers, R. et al. 2020. Using a cross-cohort comparison design to test the role of maternal smoking in pregnancy in child mental health and learning: evidence from two UK cohorts born four decades apart. International Journal of Epidemiology 49(2), pp. 390-399. (10.1093/ije/dyaa001)
- Warne, N., Caseras, X. and Rice, F. 2020. The cross-sectional and longitudinal relationship between overgeneral autobiographical memory and adolescent depression in a UK population-based cohort. Journal of Affective Disorders 266, pp. 621-625. (10.1016/j.jad.2020.02.011)
- Ng-Knight, T., Shelton, K. H., Riglin, L., Frederickson, N., McManus, I. C. and Rice, F. 2019. 'Best friends forever'? Friendship stability across school transition and associations with mental health and educational attainment. British Journal of Educational Psychology 89(4), pp. 585-599. (10.1111/bjep.12246)
- Rice, F., Riglin, L., Thapar, A. K., Heron, J., Anney, R., O'Donovan, M. C. and Thapar, A. 2019. Characterizing developmental trajectories and the role of neuropsychiatric genetic risk variants in early-onset depression. JAMA Psychiatry 76(3), pp. 306-313. (10.1001/jamapsychiatry.2018.3338)
- Nazzari, S., Fearon, P., Rice, F., Dottori, N., Ciceri, F., Molteni, M. and Frigerio, A. 2019. Beyond the HPA-axis: Exploring maternal prenatal influences on birth outcomes and stress reactivity. Psychoneuroendocrinology 101, pp. 253-262. (10.1016/j.psyneuen.2018.11.018)
- Rice, F. et al. 2019. Adolescent and adult differences in major depression symptom profiles. Journal of Affective Disorders 243, pp. 175-181. (10.1016/j.jad.2018.09.015)
- Warne, N., Collishaw, S. and Rice, F. 2019. Examining the relationship between stressful life events and overgeneral autobiographical memory in adolescents at high familial risk of depression. Memory 27(3), pp. 314-327. (10.1080/09658211.2018.1508591)
- Riglin, L. et al. 2018. The impact of schizophrenia and mood disorder risk alleles on emotional problems: investigating change from childhood to middle age. Psychological Medicine 48(13), pp. 2153-2158. (10.1017/S0033291717003634)
- Fraser, A., Cooper, M., Agha, S. S., Collishaw, S., Rice, F., Thapar, A. and Eyre, O. 2018. The presentation of depression symptoms in attention-deficit/hyperactivity disorder: comparing child and parent reports. Child and Adolescent Mental Health 23(3), pp. 243-250. (10.1111/camh.12253)
- Rice, F., Langley, K., Woodford, C., Davey Smith, G. and Thapar, A. 2018. Identifying the contribution of prenatal risk factors to offspring development and psychopathology: What designs to use and a critique of literature on maternal smoking and stress in pregnancy. Development and Psychopathology 30(3), pp. 1107-1128. (10.1017/S0954579418000421)
- Rahman, M. A. et al. 2018. School achievement as a predictor of depression and self-harm in adolescence: linked education and health record study. British Journal of Psychiatry 212(4), pp. 215-221. (10.1192/bjp.2017.69)
- Bevan Jones, R. et al. 2018. A web-based psychoeducational intervention for adolescent depression: design and development of MoodHwb. JMIR Mental Health 5(1), article number: e13. (10.2196/mental.8894)
- Ng-Knight, T., Shelton, K. H., Frederickson, N., McManus, I. C. and Rice, F. 2018. Maternal depressive symptoms and adolescent academic attainment: Testing pathways via parenting and self-control. Journal of Adolescence 62, pp. 61-69. (10.1016/j.adolescence.2017.11.003)
- Rice, F. et al. 2017. Antecedents of new-onset major depressive disorder in children and adolescents at high familial risk. JAMA Psychiatry 74(2), pp. 153-160. (10.1001/jamapsychiatry.2016.3140)
- Rice, F., Eyre, O., Riglin, L. and Potter, R. 2017. Adolescent depression and the treatment gap. The Lancet Psychiatry 4(2), pp. 86-87. (10.1016/S2215-0366(17)30004-4)
- Thapar, A. et al. 2016. Identifying key parent-reported symptoms for detecting depression in high risk adolescents. Psychiatry Research 242, pp. 210-217. (10.1016/j.psychres.2016.05.025)
- Davidovich, S., Collishaw, S., Thapar, A. K., Harold, G., Thapar, A. and Rice, F. 2016. Do better executive functions buffer the effect of current parental depression on adolescent depressive symptoms?. Journal of Affective Disorders 199, pp. 54-64. (10.1016/j.jad.2016.03.049)
- Ng-Knight, T., Shelton, K. H., Riglin, L., McManus, I., Frederickson, N. and Rice, F. 2016. A longitudinal study of self-control at the transition to secondary school: Considering the role of pubertal status and parenting. Journal of Adolescence 50, pp. 44-55. (10.1016/j.adolescence.2016.04.006)
- Neal, S., Rice, F., Ng-Knight, T., Riglin, L. and Frederickson, N. 2016. Exploring the longitudinal association between interventions to support the transition to secondary school and child anxiety. Journal of Adolescence 50, pp. 31-43. (10.1016/j.adolescence.2016.04.003)
- Riglin, L., Thapar, A., Shelton, K. H., Langley, K., Frederickson, N. and Rice, F. 2016. Profiling depression in childhood and adolescence: the role of conduct problems. Journal of Child Psychology and Psychiatry 57(4), pp. 481-490. (10.1111/jcpp.12465)
- Riglin, L. et al. 2016. Higher cognitive ability buffers stress-related depressive symptoms in adolescent girls. Development and Psychopathology 28(1), pp. 97-109. (10.1017/S0954579415000310)
- Sellers, R. et al. 2016. Examining whether offspring psychopathology influences illness course in mothers with recurrent depression using a high-risk longitudinal sample. Journal of Abnormal Psychology 125(2), pp. 256-266. (10.1037/abn0000080)
- Collishaw, S. et al. 2016. Mental health resilience in the adolescent offspring of parents with depression: a prospective longitudinal study. Lancet Psychiatry 3(1), pp. 49-57. (10.1016/S2215-0366(15)00358-2)
- McManus, I. C., Ng-Knight, T., Riglin, L., Frederickson, N., Shelton, K. H. and Rice, F. 2015. Doctor, builder, soldier, lawyer, teacher, dancer, shopkeeper, vet: exploratory study of which eleven-year olds would like to become a doctor. BMC Psychology 3(1), article number: 38. (10.1186/s40359-015-0094-z)
- Rice, F., Rawal, A., Riglin, L., Lewis, G., Lewis, G. and Dunsmuir, S. 2015. Examining reward-seeking, negative self-beliefs and over-general autobiographical memory as mechanisms of change in classroom prevention programs for adolescent depression. Journal of Affective Disorders 186, pp. 320-327. (10.1016/j.jad.2015.07.019)
- Mars, B. et al. 2015. Longitudinal symptom course in adults with recurrent depression: Impact on impairment and risk of psychopathology in offspring. Journal of Affective Disorders 182, pp. 32-38. (10.1016/j.jad.2015.04.018)
- Kilford, E. J., Foulkes, L., Potter, R., Collishaw, S., Thapar, A. and Rice, F. 2015. Affective bias and current, past and future adolescent depression: a familial high risk study. Journal of Affective Disorders 174, pp. 265-271. (10.1016/j.jad.2014.11.046)
- Rawal, A., Riglin, L., Ng-Knight, T., Collishaw, S., Thapar, A. and Rice, F. 2014. A longitudinal high-risk study of adolescent anxiety, depression and parent-severity on the developmental course of risk-adjustment. Journal of Child Psychology and Psychiatry 55(11), pp. 1270-1278. (10.1111/jcpp.12279)
- Eyre, O. et al. 2014. Reported child awareness of parental depression. Psychiatric Bulletin 38(3), pp. 122-127. (10.1192/pb.bp.113.044198)
- Riglin, L., Petrides, K., Frederickson, N. and Rice, F. 2014. The relationship between emotional problems and subsequent school attainment: A meta-analysis. Journal of Adolescence 37(4), pp. 335-346. (10.1016/j.adolescence.2014.02.010)
- Rice, F. 2014. Prospective and mutual influences of reward processing and emotional disorders in a longitudinal study of the adolescent offspring of depressed parents: the EPAD Cohort. Biological Psychiatry 75(9), pp. 195S. (10.1016/j.biopsych.2014.03.015)
- Thapar, A. K. et al. 2014. Detecting recurrent major depressive disorder within primary care rapidly and reliably using short questionnaire measures. British Journal of General Practice (BJGP) 64(618), pp. e31-7. (10.3399/bjgp14X676438)
- Lewis, K. J. et al. 2013. The Depression impairment scale for parents (DISP): A new scale for the measurement of impairment in depressed parents. Psychiatry Research 210(3), pp. 1184-1190. (10.1016/j.psychres.2013.08.001)
- Rawal, A., Collishaw, S., Thapar, A. and Rice, F. 2013. A direct method of assessing underlying cognitive risk for adolescent depression. Journal of Abnormal Child Psychology 41(8), pp. 1279-1288. (10.1007/s10802-013-9760-x)
- Mars, B. et al. 2013. Specific parental depression symptoms as risk markers for new-onset depression in high-risk offspring. The Journal of Clinical Psychiatry 74(9), pp. 925-931. (10.4088/JCP.12m08152)
- Riglin, L., Frederickson, N., Shelton, K. H. and Rice, F. 2013. A longitudinal study of psychological functioning and academic attainment at the transition to secondary school. Journal of Adolescence 36(3), pp. 507-517. (10.1016/j.adolescence.2013.03.002)
- Rice, F., Lewis, G., Harold, G. T. and Thapar, A. 2013. Examining the role of passive gene-environment correlation in childhood depression using a novel genetically sensitive design. Development and Psychopathology 25(1), pp. 37-50. (10.1017/S0954579412000880)
- Rawal, A., Collishaw, S., Thapar, A. and Rice, F. 2013. 'The risks of playing it safe': a prospective longitudinal study of response to reward in the adolescent offspring of depressed parents. Psychological Medicine 43(1), pp. 27-38. (10.1017/S0033291712001158)
- Lewis, K. J. et al. 2012. Do parents know best? Parent-reported vs. child-reported depression symptoms as predictors of future child mood disorder in a high-risk sample. Journal of Affective Disorders 141(2-3), pp. 233-236. (10.1016/j.jad.2012.03.008)
- Harold, G. T., Elam, K. K., Lewis, G., Rice, F. and Thapar, A. 2012. Interparental conflict, parent psychopathology, hostile parenting, and child antisocial behavior: Examining the role of maternal versus paternal influences using a novel genetically sensitive research design. Development and Psychopathology 24(4), pp. 1283-1295. (10.1017/S0954579412000703)
- Sellers, R. et al. 2012. Risk of psychopathology in adolescent offspring of mothers with psychopathology and recurrent depression. British Journal of Psychiatry 202(2), pp. 108-114. (10.1192/bjp.bp.111.104984)
- Potter, R. et al. 2012. Missed opportunities: mental disorder in children of parents with depression. British Journal of General Practice (BJGP) 62(600), pp. e487-e493. (10.3399/bjgp12X652355)
- Rawal, A. and Rice, F. 2012. Examining overgeneral autobiographical memory as a risk factor for adolescent depression. Journal of the American Academy of Child & Adolescent Psychiatry 51(5), pp. 518-527. (10.1016/j.jaac.2012.02.025)
- Lewis, G., Collishaw, S., Harold, G. T., Rice, F. and Thapar, A. 2012. Maternal depression and child and adolescent depression symptoms: an exploratory test for moderation by CRHR1, FKBP5 and NR3C1 gene variants. Behavior Genetics 42(1), pp. 121-132. (10.1007/s10519-011-9482-1)
- Mars, B. et al. 2012. Offspring of parents with recurrent depression: which features of parent depression index risk for offspring psychopathology?. Journal of affective disorders 136(1-2), pp. 44-53. (10.1016/j.jad.2011.09.002)
- Rawal, A. and Rice, F. 2012. A longitudinal study of processes predicting the specificity of autobiographical memory in the adolescent offspring of depressed parents. Memory 20(5), pp. 518-526. (10.1080/09658211.2012.683011)
- Shelton, K. H., Collishaw, S., Rice, F., Harold, G. T. and Thapar, A. 2011. Using a genetically informative design to examine the relationship between breastfeeding and childhood conduct problems. European Child and Adolescent Psychiatry 20(11-12), pp. 571-579. (10.1007/s00787-011-0224-y)
- Harold, G. T., Rice, F., Hay, D. F., Boivin, J., van den Bree, M. B. and Thapar, A. 2011. Familial transmission of depression and antisocial behavior symptoms: Disentangling the contribution of inherited and environmental factors and testing the mediating role of parenting. Psychological Medicine 41(6), pp. 1175-1185. (10.1017/S0033291710001753)
- Rice, F., Frederickson, N. and Seymour, J. 2011. Assessing pupil concerns about transition to secondary school. British Journal of Educational Psychology 81(2), pp. 244-263. (10.1348/000709910X519333)
- Lewis, G., Rice, F., Harold, G. T., Collishaw, S. and Thapar, A. 2011. Investigating environmental links between parent depression and child depressive/anxiety symptoms using an assisted conception design. Journal of the American Academy of Child & Adolescent Psychiatry 50(5), pp. 451-459. (10.1016/j.jaac.2011.01.015)
- Rice, F. 2010. Genetics of childhood and adolescent depression: insights into etiological heterogeneity and challenges for future genomic research. Genome Medicine 2, article number: 68. (10.1186/gm189)
- Thapar, A. et al. 2010. Response to: testing the association between smoking in pregnancy and attention-deficit/hyperactivity disorder in a novel design [Letter]. Biological psychiatry 68(4), pp. e13-e14. (10.1016/j.biopsych.2010.01.032)
- Rice, F., Harold, G. T., Boivin, J., van den Bree, M. B., Hay, D. F. and Thapar, A. 2010. The links between prenatal stress and offspring development and psychopathology: Disentangling environmental and inherited influences. Psychological Medicine 40(2), pp. 335-345. (10.1017/S0033291709005911)
- Rice, F. and Thapar, A. 2010. Estimating the relative contributions of maternal genetic, paternal genetic and intrauterine factors to offspring birth weight and head circumference. Early Human Development 86(7), pp. 425-432. (10.1016/j.earlhumdev.2010.05.021)
- Fowler, T. A. et al. 2009. Psychopathy trait scores in adolescents with childhood ADHD: the contribution of genotypes affecting MAOA, 5HTT and COMT activity. Psychiatric Genetics 19(6), pp. 312-319. (10.1097/YPG.0b013e3283328df4)
- Thapar, A. et al. 2009. Prenatal smoking might not cause Attention-Deficit/Hyperactivity Disorder: Evidence from a novel design. Biological Psychiatry 66(8), pp. 722-727. (10.1016/j.biopsych.2009.05.032)
- Shelton, K. H., Boivin, J., Hay, D. F., van den Bree, M. B., Rice, F., Harold, G. T. and Thapar, A. 2009. Examining differences in psychological adjustment problems among children conceived by assisted reproductive technologies. International Journal of Behavioral Development 33(5), pp. 385-392. (10.1177/0165025409338444)
- Boivin, J., Rice, F., Hay, D. F., Harold, G. T., Lewis, A., van den Bree, M. B. and Thapar, A. 2009. Associations between maternal older age, family environment and parent and child wellbeing in families using assisted reproductive techniques to conceive. Social Science & Medicine 68(11), pp. 1948-1955. (10.1016/j.socscimed.2009.02.036)
- Rice, F. 2009. The genetics of depression in childhood and adolescence. Current Psychiatry Reports 11(2), pp. 167-173. (10.1007/s11920-009-0026-9)
- Rice, F., Harold, G. T., Boivin, J., Hay, D. F., van den Bree, M. B. and Thapar, A. 2009. Disentangling prenatal and inherited influences in humans with an experimental design. Proceedings of the National Academy of Sciences of the United States of America 106(7), pp. 2464-2467. (10.1073/pnas.0808798106)
- Fowler, T. A. et al. 2009. Psychopathy traits in adolescents with childhood attention-deficit hyperactivity disorder. British Journal of Psychiatry 194(1), pp. 62-67. (10.1192/bjp.bp.107.046870)
- Shelton, K. H., Harold, G. T., Fowler, T. A., Rice, F., Neale, M. C., Thapar, A. and van den Bree, M. B. 2008. Parent-Child Relations, Conduct Problems and Cigarette Use in Adolescence: Examining the Role of Genetic and Environmental Factors on Patterns of Behavior. Journal of Youth and Adolescence 37(10), pp. 1216-1228. (10.1007/s10964-007-9254-7)
- Langley, K. et al. 2008. Testing for gene × environment interaction effects in attention deficit hyperactivity disorder and associated antisocial behavior. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 147B(1), pp. 49-53. (10.1002/ajmg.b.30571)
- Harold, G. T., Shelton, K. H., Rice, F., Boivin, J., Hay, D. F., van den Bree, M. B. and Thapar, A. 2008. Disentangling genetic and environmental influences on children’s development: introducing a novel methodology. Acta Psychologica Sinica 40(10), pp. 1124-1134.
- Rice, F. et al. 2007. Genetic and environmental transmission of anxiety and depression in families using a novel design [Abstract]. Behavior Genetics 37(6), pp. 788-788. (10.1007/s10519-007-9169-9)
- Thapar, A., Harold, G. T., Rice, F., Langley, K. and O'Donovan, M. C. 2007. The contribution of gene-environment interaction to psychopathology. Development and Psychopathology 19(4), pp. 989-1004. (10.1017/S0954579407000491)
- Rice, F., Lifford, K. J., Thomas, H. V. and Thapar, A. 2007. Mental health and functional outcomes of maternal and adolescent reports of adolescent depressive symptoms. Journal of the American Academy of Child & Adolescent Psychiatry 46(9), pp. 1162-1170. (10.1097/chi.0b013e3180cc255f)
- Rice, F., Jones, I. R. and Thapar, A. 2007. Impact of gestational distress and growth retardation on emotional problems in offspring - Reply [Letter]. Acta Psychiatrica Scandinavica 116(2), pp. 154-155. (10.1111/j.1600-0447.2007.01042.x)
- Fowler, T. A. et al. 2007. Exploring the relationship between genetic and environmental influences on initiation and progression of substance use. Addiction 102(3), pp. 413-422. (10.1111/j.1360-0443.2006.01694.x)
- Shelton, K. H., Lifford, K., Fowler, T., Rice, F., Harold, G. T., Thapar, A. and van den Bree, M. B. 2007. The association between conduct problems and the initiation and progression of marijuana use during adolescence: A genetic analysis across time. Behavior Genetics 37(2), pp. 314-325. (10.1007/s10519-006-9124-1)
- Rice, F., Jones, I. R. and Thapar, A. 2007. The impact of gestational stress and prenatal growth on emotional problems in offspring: a review [Review]. Acta Psychiatrica Scandinavica 115(3), pp. 171-183. (10.1111/j.1600-0447.2006.00895.x)
- van den Bree, M. B. et al. 2007. The Cardiff Study of All Wales and North West of England Twins (CaStANET): A longitudinal research program of child and adolescent development. Twin Research and Human Genetics 10(1), pp. 13-23. (10.1375/twin.10.1.13)
- Thapar, A. et al. 2007. Do intrauterine or genetic influences explain the foetal origins of chronic disease? A novel experimental method for disentangling effects. BMC Medical Research Methodology 7(1), pp. 25-32. (10.1186/1471-2288-7-25)
- Fowler, T. et al. 2007. Genetic and environmental influences on the relationship between peer alcohol use and own alcohol use in adolescents. Addiction 102(6), pp. 894-903. (10.1111/j.1360-0443.2007.01824.x)
- Rice, F. et al. 2007. Agreement between maternal report and antenatal records for a range of pre and peri-natal factors: The influence of maternal and child characteristics. Early Human Development 83(8), pp. 497-504. (10.1016/j.earlhumdev.2006.09.015)
- Thapar, A. et al. 2007. Promoting Measured Genes and Measured Environments: On the Importance of Careful Statistical Analyses and Biological Relevance—Reply [Letter]. Archives of General Psychiatry 64(3), pp. 378-379. (10.1001/archpsyc.64.3.378-b)
- Thapar, A. and Rice, F. 2006. Twin studies in pediatric depression. Child and Adolescent Psychiatric Clinics of North America 15(4), pp. 869-81. (10.1016/j.chc.2006.05.007)
- Rice, F., Harold, G. T. and Thapar, A. 2006. The effect of birth-weight with genetic susceptibility on depressive symptoms in childhood and adolescence. European Child & Adolescent Psychiatry 15(7), pp. 383-391. (10.1007/s00787-006-0545-4)
- Fowler, T. A., Rice, F., Thapar, A. and Farmer, A. 2006. Relationship between disabling fatigue and depression in children: Genetic study. British Journal of Psychiatry 189(3), pp. 247-253. (10.1192/bjp.bp.105.011379)
- Rice, F., Harold, G. T., Shelton, K. H. and Thapar, A. 2006. Family conflict interacts with genetic liability in predicting childhood and adolescent depression. Journal of the American Academy of Child and Adolescent Psychiatry 45(7), pp. 841-848. (10.1097/01.chi.0000219834.08602.44)
- Langley, K., Rice, F., van den Bree, M. B. and Thapar, A. 2005. Maternal smoking during pregnancy as an environmental risk factor for attention deficit hyperactivity disorder behaviour. A review.. Minerva Pediatrica 57(6), pp. 359-371.
- Thapar, A. et al. 2005. Catechol O-methyltransferase gene variant and birth weight predict early-onset antisocial behavior in children with attention-deficit/hyperactivity disorder. Archives of General Psychiatry 62(11), pp. 1275-1278. (10.1001/archpsyc.62.11.1275)
- Rice, F., Harold, G. T. and Thapar, A. 2005. The Link between depression in mothers and offspring: an extended twin analysis. Behavior Genetics 35(5), pp. 565-577. (10.1007/s10519-005-5432-0)
- Goody, A. J., Rice, F., Boivin, J., Harold, G. T., Hay, D. F. and Thapar, A. 2005. Twins born following fertility treatment: implications for quantitative genetic studies. Twin Research and Human Genetics 8(4), pp. 337-345. (10.1375/twin.8.4.337)
- Holmans, P. A. et al. 2005. Genome screen for loci influencing age at onset and rate of decline in late onset Alzheimer's disease. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 135B(1), pp. 24-32. (10.1002/ajmg.b.30114)
- Rice, F., van den Bree, M. B. and Thapar, A. 2004. A population-based study of anxiety as a precursor for depression in childhood and adolescence. BMC Psychiatry 4, article number: 43. (10.1186/1471-244X-4-43)
- Rice, F., Goody, A. J., Boivin, J., Hay, D. F., Harold, G. T. and Thapar, A. 2004. A novel method for disentangling the effects of genes, intrauterine and environmental risk factors [Abstract]. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 130B(1), pp. 116-117. (10.1002/ajmg.b.30101)
- Thapar, A., Boivin, J., Harold, G. T., Hay, D. F., Rice, F. and Goody, A. J. 2003. A novel method for disentangling the effects of genes, intrauterine, and environmental risk factors [Abstract]. Behavior Genetics 33(6), pp. 721-721. (10.1023/A:1026187215665)
- Thapar, A. et al. 2003. Maternal smoking during pregnancy and attention deficit hyperactivity disorder symptoms in offspring. American Journal of Psychiatry 160(11), pp. 1985-1989. (10.1176/appi.ajp.160.11.1985)
- Rice, F., Fowler, T., Scourfield, J. and Thapar, A. 2003. Anxiety and depression in childhood and adolescence: Developmental pathways, genes, and environment. Behavior Genetics 33(6), pp. 715-715.
- Rice, F., Harold, G. T. and Thapar, A. 2003. The transmission of depressive symptoms from mother to child: Genetic and environmental pathways. Behavior Genetics 33(6), pp. 716-716.
- Scourfield, J., Rice, F., Thapar, A., Harold, G. T., Martin, N. and McGuffin, P. 2003. Depressive symptoms in children and adolescents: Changing etiological influences with development. Behavior Genetics 33(6), pp. 718-719.
- Thapar, A. et al. 2003. Maternal smoking in pregnancy and attention deficit hyperactivity disorder symptoms in offspring. Behavior Genetics 33(6), pp. 720-721.
- Rice, F., Harold, G. T. and Thapar, A. 2003. Negative life events as an account of age-related differences in the genetic aetiology of depression in childhood and adolescence. Journal of Child Psychology and Psychiatry 44(7), pp. 977-987. (10.1111/1469-7610.00182)
- Scourfield, J., Rice, F., Thapar, A., Harold, G. T., Martin, N. and McGuffin, P. 2003. Depressive symptoms in children and adolescents: changing aetiological influences with development. Journal of Child Psychology and Psychiatry 44(7), pp. 968-976. (10.1111/1469-7610.00181)
- Rice, F., Abraham, R., Rudrasingham, V., Owen, M. J. and Williams, J. 2003. Memory for new information as a cognitive marker of liability to Alzheimer's disease in a high risk group: a research note. International Journal of Geriatric Psychiatry 18(2), pp. 155-160. (10.1002/gps.808)
- Rice, F., Harold, G. T. and Thapar, A. 2002. Assessing the effects of age, sex and shared environment on the genetic aetiology of depression in childhood and adolescence. Journal of Child Psychology and Psychiatry 43(8), pp. 1039-1051. (10.1111/1469-7610.00231)
- Myers, A. et al. 2002. Full genome screen for Alzheimer disease: Stage II analysis. American Journal Of Medical Genetics Part A 114(2), pp. 235-244. (10.1002/ajmg.10183)
- Rice, F., Harold, G. T. and Thapar, A. 2002. The genetic aetiology of childhood depression: a review. Journal of Child Psychology and Psychiatry 43(1), pp. 65-79. (10.1111/1469-7610.00004)
- Rice, F., Harold, G. T. and Thapar, A. 2001. Extreme depressive symptoms in children and adolescents. Behavior Genetics 31(5), pp. 467-467., article number: PMID: 15641870.
- Myers, A. et al. 2000. Susceptibility locus for Alzheimer's disease on chromosome 10. Science 290(5500), pp. 2304-2305. (10.1126/science.290.5500.2304)
- Tunstall, N. et al. 2000. Familial influence on variation in age of onset and behavioural phenotype in Alzheimer's disease. British Journal of Psychiatry 176, pp. 156-159. (10.1192/bjp.176.2.156)
- Rudrasingham, V. et al. 1999. Alpha-2 macroglobulin gene and Alzheimer disease. Nature Genetics 22(1), pp. 17-19. (10.1038/8726)
- Wavrant-DeVrieze, F. et al. 1999. No association between the alpha-2 macroglobulin I1000V polymorphism and Alzheimer's disease. Neuroscience Letters 262(2), pp. 137-139. (10.1016/S0304-3940(99)00035-X)
Book sections
- Rice, F. and Thapar, A. 2009. Depression and anxiety in childhood and adolescence: developmental pathways, genes and environment. In: Kim, Y. ed. Handbook of Behavior Genetics. New York: Springer, pp. 379-396., (10.1007/978-0-387-76727-7_26)
Other
- Padaigaitė-Gulbinienė, E., Hammerton, G., Powell, V., Rice, F. and Collishaw, S. 2024. Modifiable protective factors for mental health resilience in the offspring of depressed parents: a high-risk longitudinal cohort spanning adolescence and adulthood. Wiley Open Access.
Research
I study the origins and development of depression and anxiety in young people. I am interested in identifying causal risk and protective factors that can be targeted as part of interventions to prevent and treat depression and anxiety in young people. I am also interested in the family and genetic influences on depression and anxiety, how these operate across development, and identifying ways of supporting families and children where a parent suffers from a common mental health problem. I am interested in the relationship between school and mental health, and in transition points such as the transition to secondary school and between adolescence and adult life. I use a range of research approaches including longitudinal prospective studies of families and young people and genetic epidemiology.
I am co-director of the Wolfson Centre for Young People's Mental Health a £10 million research centre dedicated to understanding anxiety and depression in young people.
I supervise PhD students and research projects for the intercalated degree in psychology and medicine. I run a selected student component experience week in year 2 on research in child and adolescent psychiatry and developmental psychology. I also offer psychology placements.
My current active grants are all on the topic of mental health in young people.
Current funded projects:
The Wolfson Centre for Young People's Mental Health. The Wolfson Foundation £10,000,000. Joint Principal Investigator (with Stephan Collishaw). 2020 - 2026.
Further development and feasibility trial of an online psychoeducational intervention for adolescent depression. NIHR £617,465. Co-Applicant and primary supervisor to Rhys Bevan Jones. 2018 – 2022.
Early-onset depression: characterising development and identifying risks. Medical Research Council £763,680. Principal Investigator. 2017 - 2021
Social and economic consequences of health: causal inference methods and longitudinal, intergenerational data. The Health Foundation. £449,973. Co-Applicant. 2018 - 2021.
Key selected papers:
Rice, F., Riglin, L., Thapar, A.K., Heron, J., Anney, R., O'Donovan, M.C., Thapar, A. (2018). Characterising developmental trajectories and the role of psychiatric genetic risk variants to early onset depression. JAMA Psychiatry, 76(3):306-313. Published online October 14, 2018. doi:10.1001/jamapsychiatry.2018.3338
Rice, F., Sellers, R., Hammerton, G., Eyre, O., Bevan-Jones, R., Thapar, A.K., Collishaw, S., Harold, G.T., Thapar, A. (2017). Antecedents of new-onset major depressive disorder in adolescence: a longitudinal familial high-risk study. JAMA Psychiatry, 74(2), 153-160.
Rahman, M.A., Todd, C., John, A., Tan, J., Kerr, M., Potter, R., Kennedy, J., Rice, F., Brophy, S (2018). School achievement as a predictor of depression or self-harm in adolescence- a linked education and health record study. British Journal of Psychiatry. DOI: 10.1192/bjp.2017.69
Rice, F., Ng-Knight, T., Riglin, L., Powell, V., McManus, I.C., Shelton, K.H., Frederickson, N. (in press) Pupil mental health, concerns and expectations about secondary school as predictors of adjustment across the transition to secondary school: A longitudinal multi-informant study. School Mental Health.
Hughes, A., Wade, K.H., Rice, F., Dickson, M., Davies, A., Davies, N.M., Howe, L.D. (2021) Common health conditions in childhood and adolescence, school absence, and educational attainment: Mendelian randomization study. npj Science of Learning 6, 1 https://doi.org/10.1038/s41539-020-00080-6
Selous C, Kelly-Irving M, Maughan B, Eyre O, Rice F, Collishaw S. (2019). Adverse childhood experiences and adult mood problems: evidence from a five-decade prospective birth cohort Psychological Medicine. 1–8. https://doi.org/10.1017/S003329171900271X
Rice, F., Riglin, L., Lomax, T., Souter, E., Potter, R., Smith, D.J., Thapar, A.K., Thapar, A. (2018). Adolescent and adult differences in symptom profiles for major depression. Journal of Affective Disorders, 243:175-181. doi: 10.1016/j.jad.2018.09.015.
Rice, F., Langley, K., Woodford, C., Davey-Smith, G., Thapar, A. (2018). Identifying the contribution of prenatal risk factors to offspring development and psychopathology: what designs to use and a critique of literature on maternal smoking and stress in pregnancy. Development and Psychopathology, 30(3):1107-1128. doi: 10.1017/S0954579418000421
Ng-Knight, T., Riglin, L., Shelton, K.H., Frederickson, N., Rice, F. (2018). "'Best friends forever'? Friendship stability across school transition and associations with mental health and educational attainment. British Journal of Educational Psychology. doi: 10.1111/bjep.12246.
Rice, F., Rawal, A., Riglin, L., Lewis, G., Lewis, G., Dunsmuir, S (2015). Examining reward-seeking, negative self-beliefs and over-general autobiographical memory as mechanisms of change in classroom prevention programs for adolescent depression. Journal of Affective Disorders. doi: 10.1016/j.jad.2015.07.019.
Rawal, A., Collishaw, S., Thapar, A., Rice F (2013). "The risks of playing it safe": A prospective longitudinal study of response to reward in the adolescent offspring of depressed parents. Psychological Medicine, 43(1), 27-38.
Rice, F., Harold, G.T., Boivin, J., Hay, D., van den Bree, M.M.B., Thapar, A. (2010). The effects of gestational stress on offspring birth weight and psychopathology: disentangling prenatal environmental and inherited influences. Psychological Medicine 40(2):335-45.
Rice, F., Harold, G.T., Boivin, J., Hay, D., van den Bree, M.M.B., Thapar, A (2009). Disentangling prenatal and inherited influences in humans with an experimental design. Proceedings of the National Academy of Sciences USA 106 (7), 2464-2467.
Selected previous projects:
2017 - 2020 Longitudinal study of inflammation and immunity in young people at high risk of developing mental health problems. Hodge Foundation. £5,000. Principal Investigator.
2017 - 2020 The pubertal onset of mental and substance use disorders £636,183. National Health and Medical Research Australia. Associate Co-Investigator.
2011 - 2015 Nuffield Foundation - Examining pathways linking psychological adjustment and academic attainment across the transition to secondary school £118, 115 . Principal Investigator.
2012 - 2013 MRC Centenary Early Career Award £79, 422. Principal Investigator.
2009 - 2012 MRC NIRG - Neurocognitive predictors of adolescent depression: a high risk longitudinal study £392 , 053. Principal Investigator.
Teaching
I supervise research projects for the intercalated Psychology and Medicine degree. I supervise medical Student Selected Component projects. I mentor undergraduate medical students.
Biography
I studied Experimental Psychology at the University of Oxford. Prior to my current position, I was Reader in the Research Department of Clinical, Educational and Health Psychology at University College London.
Supervisions
I am interested in supervising PhD students in the areas of:
- developmental psychopathology
- risk and resilience for depression and anxiety
Contact Details
RiceF2@cardiff.ac.uk
+44 29206 88384
Hadyn Ellis Building, Room 2.18, Maindy Road, Cardiff, CF24 4HQ
+44 29206 88384
Hadyn Ellis Building, Room 2.18, Maindy Road, Cardiff, CF24 4HQ
