Dr Megan Torvell
Teams and roles for Megan Torvell
Lecturer
Lecturer
Publication
2025
- Byrne, R. A. et al. 2025. The schizophrenia-associated gene CSMD1 encodes a complement classical pathway inhibitor predominantly expressed by astrocytes and at synapses in mice and humans. Brain, Behavior, and Immunity 127, pp. 287-302. (10.1016/j.bbi.2025.03.026)
2023
- Daskoulidou, N. et al. 2023. Complement receptor 1 is expressed on brain cells and in the human brain. Glia 71(6), pp. 1522-1535. (10.1002/glia.24355)
2022
- Rossini, L. et al. 2022. Dendritic spine loss in epileptogenic Type II focal cortical dysplasia: Role of enhanced classical complement pathway activation. Brain Pathology, article number: e13141. (10.1111/bpa.13141)
- Carpanini, S. M. et al. 2022. Terminal complement pathway activation drives synaptic Loss in Alzheimer’s disease models. Acta Neuropathologica Communications 10, article number: 99. (10.1186/s40478-022-01404-w)
2021
- Torvell, M., Carpanini, S. M., Daskoulidou, N., Byrne, R. A. J., Sims, R. and Morgan, B. P. 2021. Genetic insights into the impact of complement in Alzheimer's disease. Genes 12(12), article number: 1990. (10.3390/genes12121990)
- Menzies, G. E. and Torvell, M. 2021. Exciting new tools for studying TREM2 in dementia. Structure 29(11), pp. 1215-1216. (10.1016/j.str.2021.10.009)
- Byrne, R. A. J., Torvell, M., Daskoulidou, N., Fathalla, D., Kokkali, E., Carpanini, S. M. and Morgan, B. P. 2021. Novel monoclonal antibodies against mouse C1q: characterisation and development of a quantitative ELISA for mouse C1q. Molecular Neurobiology 58(9), pp. 4323-4336. (10.1007/s12035-021-02419-5)
- Carpanini, S. M., Harwood, J. C., Baker, E., Torvell, M., Sims, R., Williams, J. and Morgan, B. P. 2021. The impact of complement genes on the risk of late-onset Alzheimer's disease. Genes 12(3), article number: 443. (10.3390/genes12030443)
2020
- Altmann, T. et al. 2020. Complement factor I deficiency: a potentially treatable cause of fulminant cerebral inflammation. Neurology, Neuroimmunology and Neuroinflammation 7(3), article number: e689. (10.1212/NXI.0000000000000689)
2019
- Carpanini, S. M., Torvell, M. and Morgan, B. P. 2019. Therapeutic inhibition of the complement system in diseases of the central nervous system. Frontiers in Immunology 10, pp. -., article number: 362. (10.3389/fimmu.2019.00362)
Articles
- Byrne, R. A. et al. 2025. The schizophrenia-associated gene CSMD1 encodes a complement classical pathway inhibitor predominantly expressed by astrocytes and at synapses in mice and humans. Brain, Behavior, and Immunity 127, pp. 287-302. (10.1016/j.bbi.2025.03.026)
- Daskoulidou, N. et al. 2023. Complement receptor 1 is expressed on brain cells and in the human brain. Glia 71(6), pp. 1522-1535. (10.1002/glia.24355)
- Rossini, L. et al. 2022. Dendritic spine loss in epileptogenic Type II focal cortical dysplasia: Role of enhanced classical complement pathway activation. Brain Pathology, article number: e13141. (10.1111/bpa.13141)
- Carpanini, S. M. et al. 2022. Terminal complement pathway activation drives synaptic Loss in Alzheimer’s disease models. Acta Neuropathologica Communications 10, article number: 99. (10.1186/s40478-022-01404-w)
- Torvell, M., Carpanini, S. M., Daskoulidou, N., Byrne, R. A. J., Sims, R. and Morgan, B. P. 2021. Genetic insights into the impact of complement in Alzheimer's disease. Genes 12(12), article number: 1990. (10.3390/genes12121990)
- Menzies, G. E. and Torvell, M. 2021. Exciting new tools for studying TREM2 in dementia. Structure 29(11), pp. 1215-1216. (10.1016/j.str.2021.10.009)
- Byrne, R. A. J., Torvell, M., Daskoulidou, N., Fathalla, D., Kokkali, E., Carpanini, S. M. and Morgan, B. P. 2021. Novel monoclonal antibodies against mouse C1q: characterisation and development of a quantitative ELISA for mouse C1q. Molecular Neurobiology 58(9), pp. 4323-4336. (10.1007/s12035-021-02419-5)
- Carpanini, S. M., Harwood, J. C., Baker, E., Torvell, M., Sims, R., Williams, J. and Morgan, B. P. 2021. The impact of complement genes on the risk of late-onset Alzheimer's disease. Genes 12(3), article number: 443. (10.3390/genes12030443)
- Altmann, T. et al. 2020. Complement factor I deficiency: a potentially treatable cause of fulminant cerebral inflammation. Neurology, Neuroimmunology and Neuroinflammation 7(3), article number: e689. (10.1212/NXI.0000000000000689)
- Carpanini, S. M., Torvell, M. and Morgan, B. P. 2019. Therapeutic inhibition of the complement system in diseases of the central nervous system. Frontiers in Immunology 10, pp. -., article number: 362. (10.3389/fimmu.2019.00362)