![Cherry-Ann Waldron](https://profiles-cardiff.imgix.net/attachments/5668?w=200&h=200&auto=format&crop=faces&fit=crop&q=90")
Dr Cherry-Ann Waldron
- Available for postgraduate supervision
Teams and roles for Cherry-Ann Waldron
Research Fellow / Senior Trial Manager
Overview
I am a Research Fellow and Senior Trial Manager in the division of Infections, Inflammation & Immunity at the Centre for Trials Research, College of Biomedical and Life Sciences, Cardiff University. I am the theme lead for Vascular Conditions.
My research interests include vascular disease, infections, surgical trials, behaviour change, public health and complex interventions.
I have extensive knowledge and experience in trial methodology and research governance.
Publication
2025
- Waldron, C. et al. 2025. Effectiveness of biomarker-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection: the BATCH RCT. Health Technology Assessment 29 (16)(10.3310/MBVA3675)
- Waldron, C. et al. 2025. Procalcitonin-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection in the UK (BATCH): a pragmatic, multicentre, open-label, two-arm, individually randomised, controlled trial. The Lancet Child & Adolescent Health 9 (2), pp.121-130. (10.1016/S2352-4642(24)00306-7)
2024
- Gwilym, B. L. et al. 2024. Long-term risk prediction after major lower limb amputation: 1-year results of the PERCEIVE study. BJS Open 8 (1) zrad135. (10.1093/bjsopen/zrad135)
- Milosevic, S. et al. 2024. Rehabilitation experiences following major lower limb amputation due to complications of vascular disease: a UK qualitative study. Disability and Rehabilitation 46 (26), pp.6477-6486. (10.1080/09638288.2024.2329747)
- Svobodova, M. et al. 2024. Patient and public involvement in the design and protocol development for a platform randomised trial to evaluate diagnostic tests to optimise antimicrobial therapy (PROTECT). NIHR Open Research 4 52. (10.3310/nihropenres.13591.1)
- Twine, C. P. et al. 2024. Challenges of using routinely collected healthcare system data in randomised trials. European Journal of Vascular and Endovascular Surgery 68 (3), pp.416-417. (10.1016/j.ejvs.2024.05.010)
2023
- Schoenbuchner, S. M. et al. 2023. Biomarker-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection: statistical analysis plan for the BATCH trial and PRECISE sub-study. Trials 24 (1) 364. (10.1186/s13063-022-06956-9)
2022
- Gwilym, B. L. et al., 2022. Short-term risk prediction after major lower limb amputation: PERCEIVE study. BJS Open 109 (12), pp.1300-1311. (10.1093/bjs/znac309)
- Lenihan, R. A. F. et al., 2022. Mid-regional pro-adrenomedullin in combination with pediatric early warning scores for risk stratification of febrile children presenting to the emergency department: secondary analysis of a nonprespecified United Kingdom cohort study. Pediatric Critical Care Medicine 23 (12), pp.980-989. (10.1097/PCC.0000000000003075)
- Milosevic, S. et al. 2022. PrEdiction of Risk and Communication of outcomE followIng major lower limb amputation: a collaboratiVE study (PERCEIVE)—protocol for the PERCEIVE qualitative study. BMJ Open 12 (1) e053159. (10.1136/bmjopen-2021-053159)
- Waldron, C. et al. 2022. Biomarker-guided duration of Antibiotic Treatment in Children Hospitalised with confirmed or suspected bacterial infection (BATCH): protocol for a randomised controlled trial. BMJ Open 12 (1) e047490. (10.1136/bmjopen-2020-047490)
2021
- Gwilym, B. et al., 2021. PERCEIVE: PrEdiction of Risk and Communication of outcome following major lower limb amputation - a collaboratIVE study. Presented at: National Research Collaborative Meeting 2020 (NRCM 2020) Virtual 19 November - 10 December 2020. Vol. 5.Vol. Supple. Wiley(10.1093/bjsopen/zrab032.089)
- Gwilym, B. L. et al., 2021. The PERCEIVE quantitative study: PrEdiction of Risk and Communication of outcome following major lower-limb amputation: protocol for a collaboratiVE study. BJS Open 5 (6) zrab118. (10.1093/bjsopen/zrab118)
- Milosevic, S. et al. 2021. Exploring patients’ experiences of analgesia after major lower limb amputation: A qualitative study. BMJ Open 11 e054618. (10.1136/bmjopen-2021-054618)
- Preece, R. et al., 2021. A systematic review and narrative synthesis of risk prediction tools used to estimate mortality, morbidity, and other outcomes following major lower limb amputation. European Journal of Vascular and Endovascular Surgery 62 (1), pp.127-135. (10.1016/j.ejvs.2021.02.038)
2020
- Ambler, G. K. et al., 2020. Umbrella review and meta-analysis of antiplatelet therapy for peripheral artery disease. British Journal of Surgery 107 (1), pp.20-32. (10.1002/bjs.11384)
- Horwood, J. et al., 2020. Increasing uptake of hepatitis C virus infection case-finding, testing, and treatment in primary care: evaluation of the HepCATT (Hepatitis C Assessment Through to Treatment) trial. British Journal of General Practice (10.3399/bjgp20X708785)
- Roberts, K. et al., 2020. Cost effectiveness of an intervention to increase uptake of hepatitis C virus testing and treatment (HepCATT): cluster randomised controlled trial in primary care. BMJ 368 (10.1136/bmj.m322)
2019
- Bosanquet, D. et al., 2019. Perineural local anaesthetic catheter after major lower limb amputation trial (PLACEMENT): results from a randomised controlled feasibility trial. BMJ Open 9 (11) e029233. (10.1136/bmjopen-2019-029233)
2018
- Bosanquet, D. C. et al. 2018. Major lower limb amputation audit – introduction and implementation of a multimodal perioperative pain management guideline. British Journal of Pain 12 (4), pp.257-258. (10.1177/2049463718800736)
- Francis, N. A. et al. 2018. Oral steroids for hearing loss associated with otitis media with effusion in children aged 2 8 years: the OSTRICH RCT. Health Technology Assessment 22 (61)(10.3310/hta22610)
- Francis, N. A. et al. 2018. Oral steroids for resolution of otitis media with effusion in children (OSTRICH): a double-blinded, placebo-controlled randomised trial. Lancet 392 (10147), pp.557-568. (10.1016/S0140-6736(18)31490-9)
2017
- Ambler, G. K. et al. 2017. Development of a core outcome set for studies involving patients undergoing major lower limb amputation for peripheral arterial disease: study protocol for a systematic review and identification of a core outcome set using a Delphi survey. Trials 18 (1) 628. (10.1186/s13063-017-2358-9)
- Bosanquet, D. C. et al., 2017. Perineural local anaesthetic catheter after major lower limb amputation trial (PLACEMENT): study protocol for a randomised controlled pilot study. Trials 18 629. (10.1186/s13063-017-2357-x)
- Chalumeau, M. et al., 2017. Comparison of microbiological diagnosis of urinary tract infection in young children by routine health service laboratories and a research laboratory: diagnostic cohort study. PLoS ONE 12 (2) e0171113. (10.1371/journal.pone.0171113)
2016
- Butler, C. C. et al., 2016. Empiric antibiotic treatment for urinary tract infection in preschool children: susceptibilities of urine sample isolates. Family Practice 33 (2), pp.127-132. (10.1093/fampra/cmv104)
- Butler, C. C. et al., 2016. Nappy pad urine samples for investigation and treatment of UTI in young children: the 'DUTY' prospective diagnostic cohort study. British Journal of General Practice 66 (648), pp.e516-e524. (10.3399/bjgp16X685873)
- Gkiousias, V. et al., 2016. Parental perceptions and understanding of information provision, management options and factors influencing the decision-making process in the treatment of children with glue ear. International Journal of Pediatric Otorhinolaryngology 89 , pp.6-12. (10.1016/j.ijporl.2016.07.021)
- Hay, A. D. et al., 2016. The Diagnosis of Urinary Tract infection in Young children (DUTY): a diagnostic prospective observational study to derive and validate a clinical algorithm for the diagnosis of urinary tract infection in children presenting to primary care with an acute illness. Health Technology Assessment 20 (51)(10.3310/hta20510)
- Hay, A. D. et al., 2016. Improving the diagnosis and treatment of urinary tract infection in young children in primary care: results from the DUTY prospective diagnostic cohort study. Annals of Family Medicine 14 (4), pp.325-336. (10.1370/afm.1954)
- Roberts, K. et al., 2016. Hepatitis C - assessment to treatment trial (HepCATT) in primary care: study protocol for a cluster randomised controlled trial. Trials 17 (1) 366. (10.1186/s13063-016-1501-3)
- Waldron, C. et al. 2016. Oral Steroids for the Resolution of Otitis Media with Effusion (OME) in Children (OSTRICH): study protocol for a randomised controlled trial. Trials 17 115. (10.1186/s13063-016-1236-1)
2015
- Butler, C. C. et al. 2015. Childhood urinary tract infection in primary care: a prospective observational study of prevalence, diagnosis, treatment, and recovery. British Journal of General Practice 65 (633), pp.e217-e223. (10.3399/bjgp15X684361)
2013
- Waldron, C. et al. 2013. Recruitment to diagnosis of urinary tract infections in young children (DUTY) study: an evaluation of the successful methods used in a primary care, prospective cohort study. [Abstract]. Trials 14 (S1), pp.-. P37. (10.1186/1745-6215-14-S1-P37)
2012
- Downing, H. et al., 2012. The diagnosis of urinary tract infections in young children (DUTY): Protocol for a diagnostic and prospective observational study to derive and validate a clinical algorithm for the diagnosis of UTI in children presenting to primary care with an acute illness. BMC Infectious Diseases 12 (1) 158. (10.1186/1471-2334-12-158)
2011
- Waldron, C. 2011. Cardiovascular risk prediction: how useful are web-based tools and do risk representation formats matter?. PhD Thesis , Cardiff University.
- Waldron, C. et al. 2011. What are effective strategies to communicate cardiovascular risk information to patients? A systematic review. Patient Education and Counseling 82 (2), pp.169-181. (10.1016/j.pec.2010.04.014)
2010
- Waldron, C. et al. 2010. The effect of different cardiovascular risk presentation formats on intentions, understanding and emotional affect: a randomised controlled trial using a web-based risk formatter (protocol). BMC Medical Informatics and Decision Making 10 (1) 41. (10.1186/1472-6947-10-41)
Articles
- Ambler, G. K. et al., 2020. Umbrella review and meta-analysis of antiplatelet therapy for peripheral artery disease. British Journal of Surgery 107 (1), pp.20-32. (10.1002/bjs.11384)
- Ambler, G. K. et al. 2017. Development of a core outcome set for studies involving patients undergoing major lower limb amputation for peripheral arterial disease: study protocol for a systematic review and identification of a core outcome set using a Delphi survey. Trials 18 (1) 628. (10.1186/s13063-017-2358-9)
- Bosanquet, D. et al., 2019. Perineural local anaesthetic catheter after major lower limb amputation trial (PLACEMENT): results from a randomised controlled feasibility trial. BMJ Open 9 (11) e029233. (10.1136/bmjopen-2019-029233)
- Bosanquet, D. C. et al. 2018. Major lower limb amputation audit – introduction and implementation of a multimodal perioperative pain management guideline. British Journal of Pain 12 (4), pp.257-258. (10.1177/2049463718800736)
- Bosanquet, D. C. et al., 2017. Perineural local anaesthetic catheter after major lower limb amputation trial (PLACEMENT): study protocol for a randomised controlled pilot study. Trials 18 629. (10.1186/s13063-017-2357-x)
- Butler, C. C. et al. 2015. Childhood urinary tract infection in primary care: a prospective observational study of prevalence, diagnosis, treatment, and recovery. British Journal of General Practice 65 (633), pp.e217-e223. (10.3399/bjgp15X684361)
- Butler, C. C. et al., 2016. Empiric antibiotic treatment for urinary tract infection in preschool children: susceptibilities of urine sample isolates. Family Practice 33 (2), pp.127-132. (10.1093/fampra/cmv104)
- Butler, C. C. et al., 2016. Nappy pad urine samples for investigation and treatment of UTI in young children: the 'DUTY' prospective diagnostic cohort study. British Journal of General Practice 66 (648), pp.e516-e524. (10.3399/bjgp16X685873)
- Chalumeau, M. et al., 2017. Comparison of microbiological diagnosis of urinary tract infection in young children by routine health service laboratories and a research laboratory: diagnostic cohort study. PLoS ONE 12 (2) e0171113. (10.1371/journal.pone.0171113)
- Downing, H. et al., 2012. The diagnosis of urinary tract infections in young children (DUTY): Protocol for a diagnostic and prospective observational study to derive and validate a clinical algorithm for the diagnosis of UTI in children presenting to primary care with an acute illness. BMC Infectious Diseases 12 (1) 158. (10.1186/1471-2334-12-158)
- Francis, N. A. et al. 2018. Oral steroids for hearing loss associated with otitis media with effusion in children aged 2 8 years: the OSTRICH RCT. Health Technology Assessment 22 (61)(10.3310/hta22610)
- Francis, N. A. et al. 2018. Oral steroids for resolution of otitis media with effusion in children (OSTRICH): a double-blinded, placebo-controlled randomised trial. Lancet 392 (10147), pp.557-568. (10.1016/S0140-6736(18)31490-9)
- Gkiousias, V. et al., 2016. Parental perceptions and understanding of information provision, management options and factors influencing the decision-making process in the treatment of children with glue ear. International Journal of Pediatric Otorhinolaryngology 89 , pp.6-12. (10.1016/j.ijporl.2016.07.021)
- Gwilym, B. L. et al. 2024. Long-term risk prediction after major lower limb amputation: 1-year results of the PERCEIVE study. BJS Open 8 (1) zrad135. (10.1093/bjsopen/zrad135)
- Gwilym, B. L. et al., 2022. Short-term risk prediction after major lower limb amputation: PERCEIVE study. BJS Open 109 (12), pp.1300-1311. (10.1093/bjs/znac309)
- Gwilym, B. L. et al., 2021. The PERCEIVE quantitative study: PrEdiction of Risk and Communication of outcome following major lower-limb amputation: protocol for a collaboratiVE study. BJS Open 5 (6) zrab118. (10.1093/bjsopen/zrab118)
- Hay, A. D. et al., 2016. The Diagnosis of Urinary Tract infection in Young children (DUTY): a diagnostic prospective observational study to derive and validate a clinical algorithm for the diagnosis of urinary tract infection in children presenting to primary care with an acute illness. Health Technology Assessment 20 (51)(10.3310/hta20510)
- Hay, A. D. et al., 2016. Improving the diagnosis and treatment of urinary tract infection in young children in primary care: results from the DUTY prospective diagnostic cohort study. Annals of Family Medicine 14 (4), pp.325-336. (10.1370/afm.1954)
- Horwood, J. et al., 2020. Increasing uptake of hepatitis C virus infection case-finding, testing, and treatment in primary care: evaluation of the HepCATT (Hepatitis C Assessment Through to Treatment) trial. British Journal of General Practice (10.3399/bjgp20X708785)
- Lenihan, R. A. F. et al., 2022. Mid-regional pro-adrenomedullin in combination with pediatric early warning scores for risk stratification of febrile children presenting to the emergency department: secondary analysis of a nonprespecified United Kingdom cohort study. Pediatric Critical Care Medicine 23 (12), pp.980-989. (10.1097/PCC.0000000000003075)
- Milosevic, S. et al. 2022. PrEdiction of Risk and Communication of outcomE followIng major lower limb amputation: a collaboratiVE study (PERCEIVE)—protocol for the PERCEIVE qualitative study. BMJ Open 12 (1) e053159. (10.1136/bmjopen-2021-053159)
- Milosevic, S. et al. 2021. Exploring patients’ experiences of analgesia after major lower limb amputation: A qualitative study. BMJ Open 11 e054618. (10.1136/bmjopen-2021-054618)
- Milosevic, S. et al. 2024. Rehabilitation experiences following major lower limb amputation due to complications of vascular disease: a UK qualitative study. Disability and Rehabilitation 46 (26), pp.6477-6486. (10.1080/09638288.2024.2329747)
- Preece, R. et al., 2021. A systematic review and narrative synthesis of risk prediction tools used to estimate mortality, morbidity, and other outcomes following major lower limb amputation. European Journal of Vascular and Endovascular Surgery 62 (1), pp.127-135. (10.1016/j.ejvs.2021.02.038)
- Roberts, K. et al., 2020. Cost effectiveness of an intervention to increase uptake of hepatitis C virus testing and treatment (HepCATT): cluster randomised controlled trial in primary care. BMJ 368 (10.1136/bmj.m322)
- Roberts, K. et al., 2016. Hepatitis C - assessment to treatment trial (HepCATT) in primary care: study protocol for a cluster randomised controlled trial. Trials 17 (1) 366. (10.1186/s13063-016-1501-3)
- Schoenbuchner, S. M. et al. 2023. Biomarker-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection: statistical analysis plan for the BATCH trial and PRECISE sub-study. Trials 24 (1) 364. (10.1186/s13063-022-06956-9)
- Svobodova, M. et al. 2024. Patient and public involvement in the design and protocol development for a platform randomised trial to evaluate diagnostic tests to optimise antimicrobial therapy (PROTECT). NIHR Open Research 4 52. (10.3310/nihropenres.13591.1)
- Twine, C. P. et al. 2024. Challenges of using routinely collected healthcare system data in randomised trials. European Journal of Vascular and Endovascular Surgery 68 (3), pp.416-417. (10.1016/j.ejvs.2024.05.010)
- Waldron, C. et al. 2010. The effect of different cardiovascular risk presentation formats on intentions, understanding and emotional affect: a randomised controlled trial using a web-based risk formatter (protocol). BMC Medical Informatics and Decision Making 10 (1) 41. (10.1186/1472-6947-10-41)
- Waldron, C. et al. 2025. Effectiveness of biomarker-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection: the BATCH RCT. Health Technology Assessment 29 (16)(10.3310/MBVA3675)
- Waldron, C. et al. 2025. Procalcitonin-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection in the UK (BATCH): a pragmatic, multicentre, open-label, two-arm, individually randomised, controlled trial. The Lancet Child & Adolescent Health 9 (2), pp.121-130. (10.1016/S2352-4642(24)00306-7)
- Waldron, C. et al. 2013. Recruitment to diagnosis of urinary tract infections in young children (DUTY) study: an evaluation of the successful methods used in a primary care, prospective cohort study. [Abstract]. Trials 14 (S1), pp.-. P37. (10.1186/1745-6215-14-S1-P37)
- Waldron, C. et al. 2022. Biomarker-guided duration of Antibiotic Treatment in Children Hospitalised with confirmed or suspected bacterial infection (BATCH): protocol for a randomised controlled trial. BMJ Open 12 (1) e047490. (10.1136/bmjopen-2020-047490)
- Waldron, C. et al. 2016. Oral Steroids for the Resolution of Otitis Media with Effusion (OME) in Children (OSTRICH): study protocol for a randomised controlled trial. Trials 17 115. (10.1186/s13063-016-1236-1)
- Waldron, C. et al. 2011. What are effective strategies to communicate cardiovascular risk information to patients? A systematic review. Patient Education and Counseling 82 (2), pp.169-181. (10.1016/j.pec.2010.04.014)
Conferences
- Gwilym, B. et al., 2021. PERCEIVE: PrEdiction of Risk and Communication of outcome following major lower limb amputation - a collaboratIVE study. Presented at: National Research Collaborative Meeting 2020 (NRCM 2020) Virtual 19 November - 10 December 2020. Vol. 5.Vol. Supple. Wiley(10.1093/bjsopen/zrab032.089)
Thesis
- Waldron, C. 2011. Cardiovascular risk prediction: how useful are web-based tools and do risk representation formats matter?. PhD Thesis , Cardiff University.
Research
Research Interests
- Infections, Inflammation and Immunity
- Vascular Disease
- Sepsis
- Biomarkers
- Antimicrobial Stewardship
- Surgical Trials
- Medical Devices
I conduct evidence-based research testing the effectiveness of interventions with the aim of reducing antibiotic resistance. Also, improving the quality of evidence and innovation in surgery, medical devices and other complex interventions.
Grants
2023: NIHR Health Technology Assessment (HTA) programme - CLopidogrel, Aspirin and Rivaroxaban after revascularisation with angioplasTY (CLARITY), (Co-Applicant, CTR study lead) £2,575,967.
2023: NIHR Health Technology Assessment (HTA) programme - Platform randomised evaluation of clinical outcomes using novel technologies to optimise antimicrobial therapy (PROTECT), (Co-Applicant) £204,987.
2022: NIHR Health Technology Assessment (HTA) programme - Perineural Local Anaesthetic Catheter aftEr Major lowEr limb amputatioN Trial (PLACEMENT), (Co-Applicant, CTR study lead) £1,635,918.
2020: NIHR Efficacy and Mechanism Evaluation (EME) programme - MR-PRo-adrenomedullin (MR-proADM) and ImmunoXpert Evaluation of procalcitonin-guided antibiotic duration in Children with Infection for Stratification of Effectiveness (PRECISE) study, (Co-Applicant) £385,450.
2020: Health and Care Research Wales RfPPB programme - PrEdiction of Risk and Communication of outcomE followIng major lower limb amputation - a collaboratiVE study (PERCEIVE), (Co-Applicant, CTR study lead) £229,225.
Biography
Honours and awards
- 2011: PhD (Medicine), Cardiff University.
- 2006: BSc (Hons) Psychology, University of Wales Institute, Cardiff.
Funded by Medical Research Council (Doctoral Training Grant).
Thesis: Cardiovascular Risk Prediction: How useful are web-based tools and do risk representation formats matter?
Professional memberships
Member of the UK Trial Managers' Network (UK TMN).
British Psychological Society - Graduate Member and Division of Health Psychology Member.
Academic positions
2020-present - Research Fellow / Senior Trial Manager, Centre for Trials Research, Cardiff University.
2012-2020 - Research Associate / Trial Manager, Centre for Trials Research, Cardiff University.
2016-2017 - Research Associate / Trial Coordinator (secondment), School of Social and Community Medicine, University of Bristol.
2011-2012 - Research Assistant / Assistant Trial Manager, South East Wales Trials Unit, Cardiff University.
Contact Details
[email protected]
+44 29206 87609
Neuadd Meirionnydd, Floor 7, University Hospital of Wales, Heath Park, Cardiff, CF14 4YS
+44 29206 87609
Neuadd Meirionnydd, Floor 7, University Hospital of Wales, Heath Park, Cardiff, CF14 4YS
Research themes
Specialisms
- Behaviour Change
- Infectious diseases
- Cardiovascular diseases
- Clinical Trials
- Vascular Conditions