Miss Rebecca Wallace
Teams and roles for Rebecca Wallace
Research Associate
Research student
Overview
I'm a post-doctoral research associate in the Viral ImmunuTherapies and Advanced Therapeutics (VITAL) group, working on developing new cancer virotherapy platforms. I am currently funded by cancer Research Wales to develop viral vectors for the treatment of glioblastoma.
During my PhD, funded by CRUK and supervised by Professor Alan Parker, we developed new adenovirus-based vectors, which can be used as cancer therapies, gene-therapy- or vaccine vectors. I was and co-supervised by Dr Carly Bliss and Professor Awen Gallimore. In my thesis, titled "Development of Precision Virotherapies Capapble of Evading Neutralising Anti-Vector Immunity" I explored how population immunity to Ad5, the most commonly used Adenovirus vector, can be circumvented to better deliver therapies to patients.
Publication
2024
- Wallace, R. 2024. Development of precision virotherapies capable of evading neutralising anti-vector immunity. PhD Thesis, Cardiff University.
- Wallace, R., Bliss, C. M. and Parker, A. L. 2024. The immune system - A double-edged sword for adenovirus-based therapies. Viruses 16(6), article number: 973. (10.3390/v16060973)
2021
- Nestic, D., Bozinovic, K., Pehar, I., Wallace, R., Parker, A. L. and Majhen, D. 2021. The revolving door of adenovirus cell entry: not all pathways are equal. Pharmaceutics 13(10), article number: 1585. (10.3390/pharmaceutics13101585)
Articles
- Wallace, R., Bliss, C. M. and Parker, A. L. 2024. The immune system - A double-edged sword for adenovirus-based therapies. Viruses 16(6), article number: 973. (10.3390/v16060973)
- Nestic, D., Bozinovic, K., Pehar, I., Wallace, R., Parker, A. L. and Majhen, D. 2021. The revolving door of adenovirus cell entry: not all pathways are equal. Pharmaceutics 13(10), article number: 1585. (10.3390/pharmaceutics13101585)
Thesis
- Wallace, R. 2024. Development of precision virotherapies capable of evading neutralising anti-vector immunity. PhD Thesis, Cardiff University.
Contact Details
Specialisms
- cancer gene therapies
- vector immunology