![Melanie Wilson](https://profiles-cardiff.imgix.net/attachments/1692?w=200&h=200&auto=format&crop=faces&fit=crop&q=90")
Overview
As a Senior Lecturer and Honorary Consultant in Oral Microbiology I have a broad remit covering research, teaching and oral microbiology service provision.
Research Theme
Tissue Engineering & Reparative Dentistry
Research Group
Microbial Effects on Tissue Function, and Tissue Repair and Remodelling
Publication
2023
- Twigg, J. A., Smith, A., Haury, C., Wilson, M., Lees, J., Waters, M. and Williams, D. W. 2023. Compositional shifts within the denture-associated bacteriome in pneumonia – an analytical cross-sectional study. Journal of Medical Microbiology 72(6) (10.1099/jmm.0.001702)
2022
- Hashim, Z. A., Maillard, J., Wilson, M. J. and Waddington, R. J. 2022. Determining the potential use of biosurfactants in preventing endodontic infections. European Journal of Oral Sciences 130(6), article number: e12900. (10.1111/eos.12900)
2021
- Williams, M., Edwards, S., Fallis, I., Wilson, M., Bradshaw, D., Pratten, J. and Williams, D. W. 2021. Preliminary study into the effects of tobacco smoke on Candida albicans. Presented at: Candida and Candidiasis 2021, Virtual, 21-27 March 2021Access Microbiology, Vol. 3 (12). Vol. 3 (12)., (10.1099/acmi.cc2021.po0124)
2019
- Morse, D. J. et al. 2019. Molecular community profiling of the bacterial microbiota associated with denture-related stomatitis. Scientific Reports 9, article number: 10228. (10.1038/s41598-019-46494-0)
- Lins, R. X., Hirata, R., Wilson, M., Lewis, M. A. O., Fidel, R. A. S. and Williams, D. 2019. Comparison of genotypes, antimicrobial resistance and virulence profiles of oral and non oral Enterococcus faecalis from Brazil, Japan and the United Kingdom. Journal of dentistry 84, pp. 49-54. (10.1016/j.jdent.2019.03.002)
- Morse, D., Wilson, M., Wei, X. q., Bradshaw, D., Lewis, M. and Williams, D. 2019. Modulation of Candida albicans virulence in in vitro biofilms by oral bacteria. Letters in Applied Microbiology 68(4), pp. 337-343. (10.1111/lam.13145)
2018
- Morse, D., Wilson, M., Wei, X., Lewis, M. A. O., Bradshaw, D. J., Murdoch, C. and Williams, D. 2018. Denture-associated biofilm infection in 3-dimensional 1 oral mucosal tissue models. Journal of Medical Microbiology 67(3), pp. 364-375. (10.1099/jmm.0.000677)
2017
- Sands, K. M. et al. 2017. Respiratory pathogen colonisation of dental plaque, the lower airways and endotracheal tube biofilms during mechanical ventilation. Journal of Critical Care 37, pp. 30-37. (10.1016/j.jcrc.2016.07.019)
2016
- Cope, A. L. et al. 2016. Antimicrobial prescribing by dentists in Wales, UK: findings of the first cycle of a clinical audit. British Dental Journal 221(1), pp. 25-30. (10.1038/sj.bdj.2016.496)
- Cavalcanti, Y. W., Wilson, M., Lewis, M., Williams, D., Senna, P. M., Del-Bel-Cury, A. A. and Silva, W. J. d. 2016. Salivary pellicles equalise surfaces' charges and modulate the virulence of Candida albicans biofilm. Archives of Oral Biology 66, pp. 129-140. (10.1016/j.archoralbio.2016.02.016)
- Sands, K. M. et al. 2016. Microbial profiling of dental plaque from mechanically ventilated patients. Journal of Medical Microbiology 65(2), pp. 147-159. (10.1099/jmm.0.000212)
2015
- Cavalcanti, Y. W. et al. 2015. Virulence and pathogenicity of Candida albicans is enhanced in biofilms containing oral bacteria. Biofouling 31(1), pp. 27-38. (10.1080/08927014.2014.996143)
2014
- Boros-Majewska, J. et al. 2014. Novel Nystatin A1 derivatives exhibiting low host cell toxicity and antifungal activity in an in vitro model of oral candidosis. Medical Microbiology and Immunology 203(5), pp. 341-355. (10.1007/s00430-014-0343-4)
- Sands, K. M., Williams, D. W., Wilson, M. J., Lewis, M. A. O., Marsh, L. L. and Wise, M. P. 2014. Mechanisms of augmented growth of Pseudomonas aeruginosa mediated by Candida albicans [Letter]. Critical Care Medicine 42(3), pp. e256. (10.1097/CCM.0000000000000113)
2013
- Sands, K. M., Williams, D. W., Wilson, M. J., Lewis, M. A. O. and Wise, M. P. 2013. The dynamics of polymicrobial biofilms [Letter]. American Journal of Respiratory and Critical Care Medicine 188(10), pp. 1266. (10.1164/rccm.201305-0916LE)
- Williams, D. W., Jordan, R. P. C., Wei, X., Alves, C. T., Wise, M. P., Wilson, M. J. and Lewis, M. A. O. 2013. Interactions of Candida albicans with host epithelial surfaces. Journal of Oral Microbiology 5, article number: 22434. (10.3402/jom.v5i0.22434)
- Waddington, R. J., Landrygan-Bakri, J., Wilson, M., Williams, D. W. and Lewis, M. A. O. 2013. Impact of bidirectional relationships between streptococcus anginosus group and host tissue matrix components on cellular activity: Role in establishment of infection. Microbiology Discovery 1(1), pp. 4-15. (10.7243/2052-6180-1-4)
2012
- Landrygan-Bakri, J., Wilson, M. J., Williams, D. W., Lewis, M. A. O. and Waddington, R. J. 2012. Real-time monitoring of adherence of Streptococcus anginosus group bacteria to extracellular matrix decorin and biglycan proteoglycans in biofilm formation. Research in Microbiology 163(6-7), pp. 436-447. (10.1016/j.resmic.2012.07.006)
- Bailey, S. E., Wilson, M., Griffiths, R., Bullock, A. D., Cowpe, J., Newcombe, R. G. and Lewis, M. A. O. 2012. Continuing dental education: evaluation of the effectiveness of a disinfection and decontamination course. European Journal of Dental Education 16(1), pp. 59-64. (10.1111/j.1600-0579.2011.00721.x)
2011
- Cairns, S. et al. 2011. Molecular analysis of microbial communities in endotracheal tube biofilms. PLoS ONE 6(3) (10.1371/journal.pone.0014759)
- Downes, J., Mantzourani, M., Beighton, D., Hooper, S. J., Wilson, M. J., Nicholson, A. and Wade, W. G. 2011. Scardovia wiggsiae sp. nov., isolated from the human oral cavity and clinical material, and emended descriptions of the genus Scardovia and Scardovia inopinata. International Journal of Systematic and Evolutionary Microbiology 61(1), pp. 25-29. (10.1099/ijs.0.019752-0)
- Hooper, S. J., Lewis, M. A. O., Wilson, M. J. and Williams, D. W. 2011. Antimicrobial activity of Citrox (R) bioflavonoid preparations against oral microorganisms. British Dental Journal 210(1) (10.1038/sj.bdj.2010.1224)
2009
- Hooper, S. J., Wilson, M. J. and Crean, S. J. 2009. Exploring the Link between Microorganisms and Oral Cancer: a Systematic Review of the Literature. Head and Neck-Journal for the Sciences and Specialties of the Head and Neck 31(9), pp. 1228-1239. (10.1002/hed.21140)
2008
- Downes, J., Hooper, S. J., Wilson, M. . J. and Wade, W. G. 2008. Prevotella histicola sp. nov., isolated from the human oral cavity. International Journal of Systematic and Evolutionary Microbiology 58(8), pp. 1788-1791. (10.1099/ijs.0.65656-0)
- Bartie, K. L., Devine, D. A., Wilson, M. J. and Lewis, M. A. O. 2008. In vitro susceptibility of the Streptococcus milleri group to antimicrobial peptides. International Endodontic Journal 41(7), pp. 586-592. (10.1111/j.1365-2591.2008.01404.x)
2007
- Hooper, S. J., Crean, S. V., Fardy, M. J., Lewis, M. A. O., Spratt, D. A., Wade, W. G. and Wilson, M. J. 2007. A molecular analysis of the bacteria present within oral Squamous Cell Carcinoma. Journal of Medical Microbiology 56(12), pp. 1651-1659. (10.1099/jmm.0.46918-0)
- Davies, C. E., Hill, K. E., Newcombe, R. G., Stephens, P., Wilson, M., Harding, K. G. and Thomas, D. W. 2007. A prospective study of the microbiology of chronic venous leg ulcers to re-evaluate the clinical predictive value of tissue biopsies and swabs. Wound Repair and Regeneration 15(1), pp. 17-22. (10.1111/j.1524-475X.2006.00180.x)
2006
- Hooper, S. J., Crean, S. V., Lewis, M. A. O., Spratt, D. A., Wade, W. G. and Wilson, M. J. 2006. Viable bacteria present within oral squamous cell carcinoma tissue. Journal of clinical microbiology 44(5), pp. 1719-1725. (10.1128/JCM.44.5.1719-1725.2006)
2005
- Howell-Jones, R. S., Wilson, M., Hill, K. E., Howard, A. J., Price, P. E. and Thomas, D. W. 2005. A review of the microbiology, antibiotic usage and resistance in chronic skin wounds. Journal of Antimicrobial Chemotherapy 55(2), pp. 143-149. (10.1093/jac/dkh513)
2004
- Bartie, K. L., Williams, D. W., Wilson, M., Potts, A. J. C. and Lewis, M. A. O. 2004. Differential invasion of Candida albicans isolates in an in vitro model of oral candidosis. Oral Microbiology And Immunolology 19(5), pp. 293-296. (10.1111/j.1399-302X.2004.00155.x)
- Davies, C. E., Hill, K. E., Wilson, M., Stephens, P., Hill, C. M., Harding, K. G. and Thomas, D. W. 2004. Use of 16S ribosomal DNA PCR and denaturing gradient gel electrophoresis for analysis of the microfloras of healing and non-healing chronic venous leg ulcers. Journal of Clinical Microbiology 42(8), pp. 3549-3557. (10.1128/JCM.42.8.3549-3557.2004)
2003
- Hill, K. E., Davies, C. E., Wilson, M., Stephens, P., Harding, K. G. and Thomas, D. W. 2003. Molecular analysis of the microflora in chronic venous leg ulceration. Journal of Medical Microbiology 52(4), pp. 365-369. (10.1099/jmm.0.05030-0)
- Stephens, P. et al. 2003. Anaerobic cocci populating the deep tissues of chronic wounds impair cellular wound healing responses in vitro. British Journal Of Dermatology 148(3), pp. 456-466. (10.1046/j.1365-2133.2003.05232.x)
2002
- Hill, K. E. et al. 2002. Heterogeneity within the gram-positive anaerobic cocci demonstrated by analysis of 16S-23S intergenic ribosomal RNA polymorphisms. Journal of Medical Microbiology 51(11), pp. 949-957.
2001
- Bartie, K. L., Williams, D. W., Wilson, M., Potts, A. J. C. and Lewis, M. A. O. 2001. PCR fingerprinting of Candida albicans associated with chronic hyperplastic candidosis and other oral conditions. Journal of clinical microbiology 39(11), pp. 4066-4075. (10.1128/JCM.39.11.4066-4075.2001)
- Wilson, M., Williams, D. W., Forbes, M., Finlay, I. G. and Lewis, M. A. O. 2001. A molecular epidemiological study of sequential oral isolates of Candida albicans from terminally ill patients. Journal Of Oral Pathology & Medicine 30(4), pp. 206-212. (10.1034/j.1600-0714.2001.300403.x)
- Williams, D. W., Coulter, W. A., Wilson, M., Potts, A. J. C. and Lewis, M. A. O. 2001. Identification of Candida dubliniensis, based on ribosomal DNA sequence analysis. British Journal of Biomedical Science 58(1), pp. 11-16.
- Williams, D. W., Bartie, K. L., Potts, A. J. C., Wilson, M., Fardy, M. J. and Lewis, M. A. O. 2001. Strain persistence of invasive Candida albicans in chronic hyperplastic candidosis that underwent malignant change. Gerodontology 18(2), pp. 73-78. (10.1111/j.1741-2358.2001.00073.x)
2000
- Williams, D. W., Wilson, M., Potts, A. J. C. and Lewis, M. A. O. 2000. Phenotypic characterisation of Candida albicans isolated from chronic hyperplastic candidosis. Journal of Medical Microbiology 49(2), pp. 199-202.
- Bartie, K. L., Wilson, M., Williams, D. W. and Lewis, M. A. O. 2000. Macrorestriction fingerprinting of "Streptococcus milleri" group bacteria by pulsed-field gel electrophoresis. Journal of Clinical Microbiology 38(6), pp. 2141-2149.
1997
- Williams, D. W., Potts, A. J. C., Wilson, M., Matthews, J. B. and Lewis, M. A. O. 1997. Characterisation of the inflammatory cell infiltrate in chronic hyperplastic candidosis of the oral mucosa. Journal of Oral Pathology & Medicine 26(2), pp. 83-89. (10.1111/j.1600-0714.1997.tb00026.x)
1996
- Williams, D. W., Wilson, M., Lewis, M. A. O. and Potts, A. J. C. 1996. Identification of Candida species in formalin fixed, paraffin wax embedded oral mucosa by sequencing of ribosomal DNA. Clinical Molecular Pathology 49, pp. M23-M28. (10.1136/mp.49.1.M23)
1995
- Williams, D. W., Wilson, M., Lewis, M. A. O. and Potts, A. J. C. 1995. Identification of Candida species by PCR and restriction fragment length polymorphism analysis of intergenic spacer regions of ribosomal DNA. Journal of Clinical Microbiology 33(9), pp. 2476-2479.
Articles
- Twigg, J. A., Smith, A., Haury, C., Wilson, M., Lees, J., Waters, M. and Williams, D. W. 2023. Compositional shifts within the denture-associated bacteriome in pneumonia – an analytical cross-sectional study. Journal of Medical Microbiology 72(6) (10.1099/jmm.0.001702)
- Hashim, Z. A., Maillard, J., Wilson, M. J. and Waddington, R. J. 2022. Determining the potential use of biosurfactants in preventing endodontic infections. European Journal of Oral Sciences 130(6), article number: e12900. (10.1111/eos.12900)
- Morse, D. J. et al. 2019. Molecular community profiling of the bacterial microbiota associated with denture-related stomatitis. Scientific Reports 9, article number: 10228. (10.1038/s41598-019-46494-0)
- Lins, R. X., Hirata, R., Wilson, M., Lewis, M. A. O., Fidel, R. A. S. and Williams, D. 2019. Comparison of genotypes, antimicrobial resistance and virulence profiles of oral and non oral Enterococcus faecalis from Brazil, Japan and the United Kingdom. Journal of dentistry 84, pp. 49-54. (10.1016/j.jdent.2019.03.002)
- Morse, D., Wilson, M., Wei, X. q., Bradshaw, D., Lewis, M. and Williams, D. 2019. Modulation of Candida albicans virulence in in vitro biofilms by oral bacteria. Letters in Applied Microbiology 68(4), pp. 337-343. (10.1111/lam.13145)
- Morse, D., Wilson, M., Wei, X., Lewis, M. A. O., Bradshaw, D. J., Murdoch, C. and Williams, D. 2018. Denture-associated biofilm infection in 3-dimensional 1 oral mucosal tissue models. Journal of Medical Microbiology 67(3), pp. 364-375. (10.1099/jmm.0.000677)
- Sands, K. M. et al. 2017. Respiratory pathogen colonisation of dental plaque, the lower airways and endotracheal tube biofilms during mechanical ventilation. Journal of Critical Care 37, pp. 30-37. (10.1016/j.jcrc.2016.07.019)
- Cope, A. L. et al. 2016. Antimicrobial prescribing by dentists in Wales, UK: findings of the first cycle of a clinical audit. British Dental Journal 221(1), pp. 25-30. (10.1038/sj.bdj.2016.496)
- Cavalcanti, Y. W., Wilson, M., Lewis, M., Williams, D., Senna, P. M., Del-Bel-Cury, A. A. and Silva, W. J. d. 2016. Salivary pellicles equalise surfaces' charges and modulate the virulence of Candida albicans biofilm. Archives of Oral Biology 66, pp. 129-140. (10.1016/j.archoralbio.2016.02.016)
- Sands, K. M. et al. 2016. Microbial profiling of dental plaque from mechanically ventilated patients. Journal of Medical Microbiology 65(2), pp. 147-159. (10.1099/jmm.0.000212)
- Cavalcanti, Y. W. et al. 2015. Virulence and pathogenicity of Candida albicans is enhanced in biofilms containing oral bacteria. Biofouling 31(1), pp. 27-38. (10.1080/08927014.2014.996143)
- Boros-Majewska, J. et al. 2014. Novel Nystatin A1 derivatives exhibiting low host cell toxicity and antifungal activity in an in vitro model of oral candidosis. Medical Microbiology and Immunology 203(5), pp. 341-355. (10.1007/s00430-014-0343-4)
- Sands, K. M., Williams, D. W., Wilson, M. J., Lewis, M. A. O., Marsh, L. L. and Wise, M. P. 2014. Mechanisms of augmented growth of Pseudomonas aeruginosa mediated by Candida albicans [Letter]. Critical Care Medicine 42(3), pp. e256. (10.1097/CCM.0000000000000113)
- Sands, K. M., Williams, D. W., Wilson, M. J., Lewis, M. A. O. and Wise, M. P. 2013. The dynamics of polymicrobial biofilms [Letter]. American Journal of Respiratory and Critical Care Medicine 188(10), pp. 1266. (10.1164/rccm.201305-0916LE)
- Williams, D. W., Jordan, R. P. C., Wei, X., Alves, C. T., Wise, M. P., Wilson, M. J. and Lewis, M. A. O. 2013. Interactions of Candida albicans with host epithelial surfaces. Journal of Oral Microbiology 5, article number: 22434. (10.3402/jom.v5i0.22434)
- Waddington, R. J., Landrygan-Bakri, J., Wilson, M., Williams, D. W. and Lewis, M. A. O. 2013. Impact of bidirectional relationships between streptococcus anginosus group and host tissue matrix components on cellular activity: Role in establishment of infection. Microbiology Discovery 1(1), pp. 4-15. (10.7243/2052-6180-1-4)
- Landrygan-Bakri, J., Wilson, M. J., Williams, D. W., Lewis, M. A. O. and Waddington, R. J. 2012. Real-time monitoring of adherence of Streptococcus anginosus group bacteria to extracellular matrix decorin and biglycan proteoglycans in biofilm formation. Research in Microbiology 163(6-7), pp. 436-447. (10.1016/j.resmic.2012.07.006)
- Bailey, S. E., Wilson, M., Griffiths, R., Bullock, A. D., Cowpe, J., Newcombe, R. G. and Lewis, M. A. O. 2012. Continuing dental education: evaluation of the effectiveness of a disinfection and decontamination course. European Journal of Dental Education 16(1), pp. 59-64. (10.1111/j.1600-0579.2011.00721.x)
- Cairns, S. et al. 2011. Molecular analysis of microbial communities in endotracheal tube biofilms. PLoS ONE 6(3) (10.1371/journal.pone.0014759)
- Downes, J., Mantzourani, M., Beighton, D., Hooper, S. J., Wilson, M. J., Nicholson, A. and Wade, W. G. 2011. Scardovia wiggsiae sp. nov., isolated from the human oral cavity and clinical material, and emended descriptions of the genus Scardovia and Scardovia inopinata. International Journal of Systematic and Evolutionary Microbiology 61(1), pp. 25-29. (10.1099/ijs.0.019752-0)
- Hooper, S. J., Lewis, M. A. O., Wilson, M. J. and Williams, D. W. 2011. Antimicrobial activity of Citrox (R) bioflavonoid preparations against oral microorganisms. British Dental Journal 210(1) (10.1038/sj.bdj.2010.1224)
- Hooper, S. J., Wilson, M. J. and Crean, S. J. 2009. Exploring the Link between Microorganisms and Oral Cancer: a Systematic Review of the Literature. Head and Neck-Journal for the Sciences and Specialties of the Head and Neck 31(9), pp. 1228-1239. (10.1002/hed.21140)
- Downes, J., Hooper, S. J., Wilson, M. . J. and Wade, W. G. 2008. Prevotella histicola sp. nov., isolated from the human oral cavity. International Journal of Systematic and Evolutionary Microbiology 58(8), pp. 1788-1791. (10.1099/ijs.0.65656-0)
- Bartie, K. L., Devine, D. A., Wilson, M. J. and Lewis, M. A. O. 2008. In vitro susceptibility of the Streptococcus milleri group to antimicrobial peptides. International Endodontic Journal 41(7), pp. 586-592. (10.1111/j.1365-2591.2008.01404.x)
- Hooper, S. J., Crean, S. V., Fardy, M. J., Lewis, M. A. O., Spratt, D. A., Wade, W. G. and Wilson, M. J. 2007. A molecular analysis of the bacteria present within oral Squamous Cell Carcinoma. Journal of Medical Microbiology 56(12), pp. 1651-1659. (10.1099/jmm.0.46918-0)
- Davies, C. E., Hill, K. E., Newcombe, R. G., Stephens, P., Wilson, M., Harding, K. G. and Thomas, D. W. 2007. A prospective study of the microbiology of chronic venous leg ulcers to re-evaluate the clinical predictive value of tissue biopsies and swabs. Wound Repair and Regeneration 15(1), pp. 17-22. (10.1111/j.1524-475X.2006.00180.x)
- Hooper, S. J., Crean, S. V., Lewis, M. A. O., Spratt, D. A., Wade, W. G. and Wilson, M. J. 2006. Viable bacteria present within oral squamous cell carcinoma tissue. Journal of clinical microbiology 44(5), pp. 1719-1725. (10.1128/JCM.44.5.1719-1725.2006)
- Howell-Jones, R. S., Wilson, M., Hill, K. E., Howard, A. J., Price, P. E. and Thomas, D. W. 2005. A review of the microbiology, antibiotic usage and resistance in chronic skin wounds. Journal of Antimicrobial Chemotherapy 55(2), pp. 143-149. (10.1093/jac/dkh513)
- Bartie, K. L., Williams, D. W., Wilson, M., Potts, A. J. C. and Lewis, M. A. O. 2004. Differential invasion of Candida albicans isolates in an in vitro model of oral candidosis. Oral Microbiology And Immunolology 19(5), pp. 293-296. (10.1111/j.1399-302X.2004.00155.x)
- Davies, C. E., Hill, K. E., Wilson, M., Stephens, P., Hill, C. M., Harding, K. G. and Thomas, D. W. 2004. Use of 16S ribosomal DNA PCR and denaturing gradient gel electrophoresis for analysis of the microfloras of healing and non-healing chronic venous leg ulcers. Journal of Clinical Microbiology 42(8), pp. 3549-3557. (10.1128/JCM.42.8.3549-3557.2004)
- Hill, K. E., Davies, C. E., Wilson, M., Stephens, P., Harding, K. G. and Thomas, D. W. 2003. Molecular analysis of the microflora in chronic venous leg ulceration. Journal of Medical Microbiology 52(4), pp. 365-369. (10.1099/jmm.0.05030-0)
- Stephens, P. et al. 2003. Anaerobic cocci populating the deep tissues of chronic wounds impair cellular wound healing responses in vitro. British Journal Of Dermatology 148(3), pp. 456-466. (10.1046/j.1365-2133.2003.05232.x)
- Hill, K. E. et al. 2002. Heterogeneity within the gram-positive anaerobic cocci demonstrated by analysis of 16S-23S intergenic ribosomal RNA polymorphisms. Journal of Medical Microbiology 51(11), pp. 949-957.
- Bartie, K. L., Williams, D. W., Wilson, M., Potts, A. J. C. and Lewis, M. A. O. 2001. PCR fingerprinting of Candida albicans associated with chronic hyperplastic candidosis and other oral conditions. Journal of clinical microbiology 39(11), pp. 4066-4075. (10.1128/JCM.39.11.4066-4075.2001)
- Wilson, M., Williams, D. W., Forbes, M., Finlay, I. G. and Lewis, M. A. O. 2001. A molecular epidemiological study of sequential oral isolates of Candida albicans from terminally ill patients. Journal Of Oral Pathology & Medicine 30(4), pp. 206-212. (10.1034/j.1600-0714.2001.300403.x)
- Williams, D. W., Coulter, W. A., Wilson, M., Potts, A. J. C. and Lewis, M. A. O. 2001. Identification of Candida dubliniensis, based on ribosomal DNA sequence analysis. British Journal of Biomedical Science 58(1), pp. 11-16.
- Williams, D. W., Bartie, K. L., Potts, A. J. C., Wilson, M., Fardy, M. J. and Lewis, M. A. O. 2001. Strain persistence of invasive Candida albicans in chronic hyperplastic candidosis that underwent malignant change. Gerodontology 18(2), pp. 73-78. (10.1111/j.1741-2358.2001.00073.x)
- Williams, D. W., Wilson, M., Potts, A. J. C. and Lewis, M. A. O. 2000. Phenotypic characterisation of Candida albicans isolated from chronic hyperplastic candidosis. Journal of Medical Microbiology 49(2), pp. 199-202.
- Bartie, K. L., Wilson, M., Williams, D. W. and Lewis, M. A. O. 2000. Macrorestriction fingerprinting of "Streptococcus milleri" group bacteria by pulsed-field gel electrophoresis. Journal of Clinical Microbiology 38(6), pp. 2141-2149.
- Williams, D. W., Potts, A. J. C., Wilson, M., Matthews, J. B. and Lewis, M. A. O. 1997. Characterisation of the inflammatory cell infiltrate in chronic hyperplastic candidosis of the oral mucosa. Journal of Oral Pathology & Medicine 26(2), pp. 83-89. (10.1111/j.1600-0714.1997.tb00026.x)
- Williams, D. W., Wilson, M., Lewis, M. A. O. and Potts, A. J. C. 1996. Identification of Candida species in formalin fixed, paraffin wax embedded oral mucosa by sequencing of ribosomal DNA. Clinical Molecular Pathology 49, pp. M23-M28. (10.1136/mp.49.1.M23)
- Williams, D. W., Wilson, M., Lewis, M. A. O. and Potts, A. J. C. 1995. Identification of Candida species by PCR and restriction fragment length polymorphism analysis of intergenic spacer regions of ribosomal DNA. Journal of Clinical Microbiology 33(9), pp. 2476-2479.
Conferences
- Williams, M., Edwards, S., Fallis, I., Wilson, M., Bradshaw, D., Pratten, J. and Williams, D. W. 2021. Preliminary study into the effects of tobacco smoke on Candida albicans. Presented at: Candida and Candidiasis 2021, Virtual, 21-27 March 2021Access Microbiology, Vol. 3 (12). Vol. 3 (12)., (10.1099/acmi.cc2021.po0124)
Research
As an MRC Clinical Training Fellow, my focus was the application of molecular methods to the study of the dental plaque bacterial community. This interest has continued throughout my career and has been extended to the study of other complex microbial communities, including the chronic wound microflora, bacteria associated with oral cancer, and the biofilms involved in community and ventilator associated pneumonia. Other research interests relate to antimicrobial resistance, the antimicrobial and antibiofilm effects of probiotics and their products, and host pathogen interactions, for example the interaction of microaerophilic streptococci with extracellular matrix components and Candida species with host tissues.
I oversee a specialist diagnostic oral microbiology service which receives a range of specimen types including saliva, pus, dental plaque and fluid samples from patients with orofacial infection. In addition to supporting the optimal management of infection for the individual patient, this facility provides data on profiles of pathogens associated with disease in addition to susceptibility to antimicrobial agents. Such surveillance is fundamental to the global action against increasing antimicrobial resistance and the unit collaborates with partners in the UK and Europe.
In addition, I act as Infection Control and Antimicrobial Stewardship Advisor to the Dental School and facilitate research in these areas including national audits of antimicrobial prescribing. As Chair of the UK Association of Clinical Microbiologists I am actively involved in increasing the UK capacity for research and service provision in all aspects of oral microbiology.
Teaching
I am involved in teaching and assessment for the following topics at all levels in both Undergraduate and Postgraduate Programmes.
Microbiology of oral disease
Microbiology of systemic disease
Infection control
Decontamination
Management of orofacial infection
Antimicrobial stewardship
I have acted as External Examiner at Universities within the UK and overseas at both undergraduate and postgraduate level.
Biography
Position 2003-present
Senior Lecturer and Honorary Consultant in Oral Microbiology
Academic Qualifications
|
2002 |
FRCPath |
Royal College of Pathologists |
|
1996 |
PhD |
University of Wales College of Medicine |
|
1993 |
FDS |
Royal College of Surgeons (London) |
|
1989 |
BDS |
Queens University Belfast |
|
1987 |
BSc (Hons) |
Medical Microbiology, Queens University Belfast |
Professional Memberships and Roles
Chair Association of Clinical oral Microbiologists
Specialty Advisor to SAC Additional Dental Specialties
Specialty Member of Senate of Dental Specialties
Member of Microbiology Society
Editorial Board Journal of Dentistry
Chair Health and Safety Advisory Group Cardiff University and Cardiff and Vale University Health Board
Contact Details
WilsonMJ@cardiff.ac.uk
+44 29225 10655
University Dental Hospital, Room 479, Heath Park, Cardiff, CF14 4XY
+44 29225 10655
University Dental Hospital, Room 479, Heath Park, Cardiff, CF14 4XY