![Yidan Xue BEng (Hons) DPhil](https://profiles-cardiff.imgix.net/attachments/5525?w=200&h=200&auto=format&crop=faces&fit=crop&q=90")
Dr Yidan Xue
BEng (Hons) DPhil
Post Doctoral Research Associate
Overview
I am currently a postdoctoral research associate working with Drs Katerina Kaouri and Thomas Woolley on developing an indoor epidemic simulator to inform and mitigate future epidemic outbreaks, in close collaboration with Prof Wassim Jabi and funded by a UKRI Impact Acceleration Grant. Unlike existing solutions, our simulator integrates detailed indoor geometry, architectural design and movement of individuals, along with novel mathematical models of virus spread and flow. The architectural design is undertaken through Topologicpy, a well-established architectural digital design software developed at Professor Jabi. The simulator will provide the infection risk of an infectious disease for a group of people in an indoor space with a given schedule.
An example simulation in a care home scenario. The agents are represented by cylinders, with the infected and healthy individuals depicted with red and green, respectively. The virus concentration in the indoor space is also visualised (around the infectious individual).
Before my current position, I was an EPSRC Postdoctoral Research Associate at the Mathematical Institute of the University of Oxford, working on Stokes flows and microparticle transport in micro-vessel bifurcations with Professor Sarah Waters. With Professor Nick Trefethen, we developed a rational approximation algorithm for computing 2D Stokes flows. Before this, I did my DPhil on modelling oxygen transport and tissue damage in the human brain with Professor Stephen Payne at Institute of Biomedical Engineering (IBME). I received my BEng (Hons) in Mechanical Engineering from the University of Edinburgh.
Publication
2023
- Xue, Y., Payne, S. J. and Waters, S. L. 2023. Stokes flows in a 2D bifurcation. [Online]. arXiv: arXiv. (10.48550/ARXIV.2309.11230) Available at: https://arxiv.org/abs/2309.11230
- Xue, Y., Waters, S. L. and Trefethen, L. N. 2023. Computation of 2D Stokes flows via lightning and AAA rational approximation. [Online]. arXiv: arXiv. (10.48550/ARXIV.2306.13545) Available at: https://arxiv.org/abs/2306.13545
2022
- Xue, Y., Georgakopoulou, T., van der Wijk, A., Józsa, T. I., van Bavel, E. and Payne, S. J. 2022. Quantification of hypoxic regions distant from occlusions in cerebral penetrating arteriole trees. PLoS Computational Biology 18(8), article number: e1010166. (10.1371/journal.pcbi.1010166)
- Xue, Y. 2022. Modelling oxygen transport and tissue damage in the human brain. PhD Thesis, University of Oxford.
2021
- Miller, C. et al. 2021. In silico trials for treatment of acute ischemic stroke: design and implementation. Computers in Biology and Medicine 137, article number: 104802. (10.1016/j.compbiomed.2021.104802)
- Xue, Y., El-Bouri, W. K., Józsa, T. I. and Payne, S. J. 2021. Modelling the effects of cerebral microthrombi on tissue oxygenation and cell death. Journal of Biomechanics 127, article number: 110705. (10.1016/j.jbiomech.2021.110705)
2020
- Xue, Y., Hellmuth, R. and Shin, D. 2020. Formation of vortices in idealised branching vessels: a CFD benchmark study. Cardiovascular Engineering and Technology 11(5), pp. 544-559. (10.1007/s13239-020-00477-9)
Articles
- Xue, Y., Georgakopoulou, T., van der Wijk, A., Józsa, T. I., van Bavel, E. and Payne, S. J. 2022. Quantification of hypoxic regions distant from occlusions in cerebral penetrating arteriole trees. PLoS Computational Biology 18(8), article number: e1010166. (10.1371/journal.pcbi.1010166)
- Miller, C. et al. 2021. In silico trials for treatment of acute ischemic stroke: design and implementation. Computers in Biology and Medicine 137, article number: 104802. (10.1016/j.compbiomed.2021.104802)
- Xue, Y., El-Bouri, W. K., Józsa, T. I. and Payne, S. J. 2021. Modelling the effects of cerebral microthrombi on tissue oxygenation and cell death. Journal of Biomechanics 127, article number: 110705. (10.1016/j.jbiomech.2021.110705)
- Xue, Y., Hellmuth, R. and Shin, D. 2020. Formation of vortices in idealised branching vessels: a CFD benchmark study. Cardiovascular Engineering and Technology 11(5), pp. 544-559. (10.1007/s13239-020-00477-9)
Thesis
- Xue, Y. 2022. Modelling oxygen transport and tissue damage in the human brain. PhD Thesis, University of Oxford.
Websites
- Xue, Y., Payne, S. J. and Waters, S. L. 2023. Stokes flows in a 2D bifurcation. [Online]. arXiv: arXiv. (10.48550/ARXIV.2309.11230) Available at: https://arxiv.org/abs/2309.11230
- Xue, Y., Waters, S. L. and Trefethen, L. N. 2023. Computation of 2D Stokes flows via lightning and AAA rational approximation. [Online]. arXiv: arXiv. (10.48550/ARXIV.2306.13545) Available at: https://arxiv.org/abs/2306.13545
Research
Research interests: Fluid mechanics, biomechanics, computational biology, homogenisation, cerebral blood flow and metabolism, in silico clinical trial, oxygen transport, microcirculation, medical imaging