Dr Claire Kelly
Timau a rolau for Claire Kelly
Uwch Gymrawd Ymchwil Anrhydeddus
Ysgol y Biowyddorau
Cyhoeddiad
2026
- Barker, R. A. et al., 2026. The TransEuro open-label trial of human fetal ventral mesencephalic transplantation in patients with moderate Parkinson's disease.. Nature Biotechnology 44 , pp.70-78. (10.1038/s41587-025-02567-2)
2021
- Choompoo, N. et al. 2021. Induced pluripotent stem cells derived from the developing striatum as a potential donor source for cell replacement therapy for Huntington disease. Cytotherapy 23 (2), pp.111-118. (10.1016/j.jcyt.2020.06.001)
2019
- Noakes, Z. et al. 2019. Human pluripotent stem cell-derived striatal interneurons: differentiation and maturation in vitro and in the rat brain. Stem Cell Reports 12 (2), pp.191-200. (10.1016/j.stemcr.2018.12.014)
2017
- Precious, S. V. et al., 2017. Is there a place for human fetal-derived stem cells for cell replacement therapy in Huntington's disease?. Neurochemistry International 106 , pp.114-121. (10.1016/j.neuint.2017.01.016)
2016
- Kelly, C. , Johnson, I. G. and Morgan, M. Z. 2016. Oral cancer: exploring the stories in UK newspapers. British Dental Journal 221 , pp.247-250. (10.1038/sj.bdj.2016.643)
- Precious, S. V. et al., 2016. FoxP1 marks medium spiny neurons from precursors to maturity and is required for their differentiation. Experimental Neurology 282 , pp.9-18. (10.1016/j.expneurol.2016.05.002)
- Lelos, M. et al. 2016. Amelioration of non-motor dysfunctions after transplantation of human dopamine neurons in a model of Parkinson's disease. Experimental Neurology 278 , pp.54-61. (10.1016/j.expneurol.2016.02.003)
- Precious, S. V. et al., 2016. Can manipulation of differentiation conditions eliminate proliferative cells from a population of ES cell-derived forebrain cells?. Neurogenesis 3 (1) e1127311. (10.1080/23262133.2015.1127311)
2015
- Straccia, M. et al., 2015. Quantitative high-throughput gene expression profiling of human striatal development to screen stem cell-derived medium spiny neurons. Molecular Therapy - Methods & Clinical Development 2 15030. (10.1038/mtm.2015.30)
- Arber, C. et al., 2015. Activin A directs striatal projection neuron differentiation of human pluripotent stem cells. Development 142 (7), pp.1375-1386. (10.1242/dev.117093)
- Roberton, V. H. , Rosser, A. E. and Kelly, C. M. 2015. Neonatal desensitization for the study of regenerative medicine. Regenerative Medicine 10 (3), pp.265-274. (10.2217/rme.14.76)
2014
- Rinaldi, F. et al., 2014. Cross-regulation of Connexin43 and β-catenin influences differentiation of human neural progenitor cells. Cell Death and Disease 5 (1) e1017. (10.1038/cddis.2013.546)
2013
- Roberton, V. H. et al. 2013. Is the adult mouse striatum a hostile host for neural transplant survival?. NeuroReport 24 (18), pp.1010-1015. (10.1097/WNR.0000000000000066)
- Heuer, A. et al. 2013. Dopamine-rich grafts alleviate deficits in contralateral response space induced by extensive dopamine depletion in rats. Experimental Neurology 247 , pp.485-495. (10.1016/j.expneurol.2013.01.020)
- Kelly, C. , Battersby, A. and Rosser, A. E. 2013. Stem cell transplantation for neurodegenerative disease: a distant dream?. Aging Health 9 (2), pp.139-148. (10.2217/ahe.13.16)
2012
- Kelly, C. et al. 2012. Reply to "Neonatal desensitization does not universally prevent xenograft rejection". Nature Methods 9 (9), pp.858. (10.1038/nmeth.2144)
- Evans, A. E. et al. 2012. Molecular regulation of striatal development: a review. Anatomy Research International 2012 106529. (10.1155/2012/106529)
- Smith, G. A. et al. 2012. L-dopa and graft-induced dyskinesia in the 6-OHDA-lesioned mouse [Abstract]. Cell Transplantation 21 (4), pp.792-792.
- Zietlow, R. et al. 2012. Long-term expansion of human foetal neural progenitors leads to reduced graft viability in the neonatal rat brain. Experimental Neurology 235 (2), pp.563-573. (10.1016/j.expneurol.2012.03.010)
2011
- Cordero-Llana, O. et al., 2011. Clusterin secreted by astrocytes enhances neuronal differentiation from human neural precursor cells. Cell Death and Differentiation 18 (5), pp.907-913. (10.1038/cdd.2010.169)
- Hollins, A. J. et al. 2011. Transplantation of differentiated human embryonic stem cells into a Huntington's Disease model: The challenges of generating neural cells suitable for replacement therapy in neurodegenerative disease. Cell Transplantation 20 (4), pp.563-564.
- Kelly, C. et al. 2011. Medical terminations of pregnancy: A viable source of tissue for cell replacement therapy for neurodegenerative disorders. Cell Transplantation 20 (4), pp.503-513. (10.3727/096368910X546580)
- Rosser, A. E. , Kelly, C. and Dunnett, S. B. 2011. Cell transplantation for Huntington's disease: practical and clinical considerations. Future Neurology 6 (1), pp.45-62. (10.2217/fnl.10.78)
2009
- Kelly, C. , Handley, O. J. and Rosser, A. 2009. Human trials for neurodegenerative disease. In: Scolding, N. J. and Gordon, D. eds. Neural Cell Transplantation: Methods and Protocols. Methods in Molecular Biology Vol. 549.New York: Humana Press. , pp.33-47. (10.1007/978-1-60327-931-4_3)
- Kelly, C. , Dunnett, S. B. and Rosser, A. E. 2009. Medium spiny neurons for transplantation in Huntington's disease. Biochemical Society Transactions 37 (1), pp.323-328. (10.1042/BST0370323)
- Kelly, C. M. et al. 2009. Neonatal desensitization allows long-term survival of neural xenotransplants without immunosuppression. Nature Methods 6 (4), pp.271-273. (10.1038/nmeth.1308)
- Paynter, S. J. et al. 2009. Membrane permeability coefficients of murine primary neural brain cells in the presence of cryoprotectant. Cryoletters 29 (1), pp.84.
- Paynter, S. J. et al. 2009. Membrane permeability coefficients of murine primary neural brain cells in the presence of cryoprotectant. Cryobiology 58 (3), pp.308-314. (10.1016/j.cryobiol.2009.02.008)
2007
- Kelly, C. et al. 2007. Striatal graft projections are influencd by donor cell type and not the immunogenic background. Brain 130 , pp.1317-1329. (10.1093/brain/awm053)
- Joannides, A. J. et al., 2007. Environmental signals regulate lineage choice and temporal maturation of neural stem cells from human embryonic stem cells. Brain 130 (5), pp.1263-1275. (10.1093/brain/awm070)
- Kelly, C. et al. 2007. Striatal graft projections are influenced by donor cell type and not the immunogenic background. Brain 130 (5), pp.1317-1329. (10.1093/brain/awm053)
2005
- Kelly, C. et al. 2005. EGF and FGF-2 responsiveness of rat and mouse neural precursors derived from the embryonic CNS. Brain Research Bulletin 68 (1-2), pp.83-94. (10.1016/j.brainresbull.2005.08.020)
- Kelly, C. M. 2005. Neural stem cells for cell replacement therapy in Huntington's disease. PhD Thesis , Cardiff University.
Adrannau llyfrau
- Kelly, C. , Handley, O. J. and Rosser, A. 2009. Human trials for neurodegenerative disease. In: Scolding, N. J. and Gordon, D. eds. Neural Cell Transplantation: Methods and Protocols. Methods in Molecular Biology Vol. 549.New York: Humana Press. , pp.33-47. (10.1007/978-1-60327-931-4_3)
Erthyglau
- Barker, R. A. et al., 2026. The TransEuro open-label trial of human fetal ventral mesencephalic transplantation in patients with moderate Parkinson's disease.. Nature Biotechnology 44 , pp.70-78. (10.1038/s41587-025-02567-2)
- Choompoo, N. et al. 2021. Induced pluripotent stem cells derived from the developing striatum as a potential donor source for cell replacement therapy for Huntington disease. Cytotherapy 23 (2), pp.111-118. (10.1016/j.jcyt.2020.06.001)
- Noakes, Z. et al. 2019. Human pluripotent stem cell-derived striatal interneurons: differentiation and maturation in vitro and in the rat brain. Stem Cell Reports 12 (2), pp.191-200. (10.1016/j.stemcr.2018.12.014)
- Precious, S. V. et al., 2017. Is there a place for human fetal-derived stem cells for cell replacement therapy in Huntington's disease?. Neurochemistry International 106 , pp.114-121. (10.1016/j.neuint.2017.01.016)
- Kelly, C. , Johnson, I. G. and Morgan, M. Z. 2016. Oral cancer: exploring the stories in UK newspapers. British Dental Journal 221 , pp.247-250. (10.1038/sj.bdj.2016.643)
- Precious, S. V. et al., 2016. FoxP1 marks medium spiny neurons from precursors to maturity and is required for their differentiation. Experimental Neurology 282 , pp.9-18. (10.1016/j.expneurol.2016.05.002)
- Lelos, M. et al. 2016. Amelioration of non-motor dysfunctions after transplantation of human dopamine neurons in a model of Parkinson's disease. Experimental Neurology 278 , pp.54-61. (10.1016/j.expneurol.2016.02.003)
- Precious, S. V. et al., 2016. Can manipulation of differentiation conditions eliminate proliferative cells from a population of ES cell-derived forebrain cells?. Neurogenesis 3 (1) e1127311. (10.1080/23262133.2015.1127311)
- Straccia, M. et al., 2015. Quantitative high-throughput gene expression profiling of human striatal development to screen stem cell-derived medium spiny neurons. Molecular Therapy - Methods & Clinical Development 2 15030. (10.1038/mtm.2015.30)
- Arber, C. et al., 2015. Activin A directs striatal projection neuron differentiation of human pluripotent stem cells. Development 142 (7), pp.1375-1386. (10.1242/dev.117093)
- Roberton, V. H. , Rosser, A. E. and Kelly, C. M. 2015. Neonatal desensitization for the study of regenerative medicine. Regenerative Medicine 10 (3), pp.265-274. (10.2217/rme.14.76)
- Rinaldi, F. et al., 2014. Cross-regulation of Connexin43 and β-catenin influences differentiation of human neural progenitor cells. Cell Death and Disease 5 (1) e1017. (10.1038/cddis.2013.546)
- Roberton, V. H. et al. 2013. Is the adult mouse striatum a hostile host for neural transplant survival?. NeuroReport 24 (18), pp.1010-1015. (10.1097/WNR.0000000000000066)
- Heuer, A. et al. 2013. Dopamine-rich grafts alleviate deficits in contralateral response space induced by extensive dopamine depletion in rats. Experimental Neurology 247 , pp.485-495. (10.1016/j.expneurol.2013.01.020)
- Kelly, C. , Battersby, A. and Rosser, A. E. 2013. Stem cell transplantation for neurodegenerative disease: a distant dream?. Aging Health 9 (2), pp.139-148. (10.2217/ahe.13.16)
- Kelly, C. et al. 2012. Reply to "Neonatal desensitization does not universally prevent xenograft rejection". Nature Methods 9 (9), pp.858. (10.1038/nmeth.2144)
- Evans, A. E. et al. 2012. Molecular regulation of striatal development: a review. Anatomy Research International 2012 106529. (10.1155/2012/106529)
- Smith, G. A. et al. 2012. L-dopa and graft-induced dyskinesia in the 6-OHDA-lesioned mouse [Abstract]. Cell Transplantation 21 (4), pp.792-792.
- Zietlow, R. et al. 2012. Long-term expansion of human foetal neural progenitors leads to reduced graft viability in the neonatal rat brain. Experimental Neurology 235 (2), pp.563-573. (10.1016/j.expneurol.2012.03.010)
- Cordero-Llana, O. et al., 2011. Clusterin secreted by astrocytes enhances neuronal differentiation from human neural precursor cells. Cell Death and Differentiation 18 (5), pp.907-913. (10.1038/cdd.2010.169)
- Hollins, A. J. et al. 2011. Transplantation of differentiated human embryonic stem cells into a Huntington's Disease model: The challenges of generating neural cells suitable for replacement therapy in neurodegenerative disease. Cell Transplantation 20 (4), pp.563-564.
- Kelly, C. et al. 2011. Medical terminations of pregnancy: A viable source of tissue for cell replacement therapy for neurodegenerative disorders. Cell Transplantation 20 (4), pp.503-513. (10.3727/096368910X546580)
- Rosser, A. E. , Kelly, C. and Dunnett, S. B. 2011. Cell transplantation for Huntington's disease: practical and clinical considerations. Future Neurology 6 (1), pp.45-62. (10.2217/fnl.10.78)
- Kelly, C. , Dunnett, S. B. and Rosser, A. E. 2009. Medium spiny neurons for transplantation in Huntington's disease. Biochemical Society Transactions 37 (1), pp.323-328. (10.1042/BST0370323)
- Kelly, C. M. et al. 2009. Neonatal desensitization allows long-term survival of neural xenotransplants without immunosuppression. Nature Methods 6 (4), pp.271-273. (10.1038/nmeth.1308)
- Paynter, S. J. et al. 2009. Membrane permeability coefficients of murine primary neural brain cells in the presence of cryoprotectant. Cryoletters 29 (1), pp.84.
- Paynter, S. J. et al. 2009. Membrane permeability coefficients of murine primary neural brain cells in the presence of cryoprotectant. Cryobiology 58 (3), pp.308-314. (10.1016/j.cryobiol.2009.02.008)
- Kelly, C. et al. 2007. Striatal graft projections are influencd by donor cell type and not the immunogenic background. Brain 130 , pp.1317-1329. (10.1093/brain/awm053)
- Joannides, A. J. et al., 2007. Environmental signals regulate lineage choice and temporal maturation of neural stem cells from human embryonic stem cells. Brain 130 (5), pp.1263-1275. (10.1093/brain/awm070)
- Kelly, C. et al. 2007. Striatal graft projections are influenced by donor cell type and not the immunogenic background. Brain 130 (5), pp.1317-1329. (10.1093/brain/awm053)
- Kelly, C. et al. 2005. EGF and FGF-2 responsiveness of rat and mouse neural precursors derived from the embryonic CNS. Brain Research Bulletin 68 (1-2), pp.83-94. (10.1016/j.brainresbull.2005.08.020)
Gosodiad
- Kelly, C. M. 2005. Neural stem cells for cell replacement therapy in Huntington's disease. PhD Thesis , Cardiff University.