Dr Claire Kelly

2025

• Barker, R. A. et al. 2025. The TransEuro open-label trial of human fetal ventral mesencephalic transplantation in patients with moderate Parkinson's disease.. Nature Biotechnology (10.1038/s41587-025-02567-2)

2021

• Choompoo, N. et al. 2021. Induced pluripotent stem cells derived from the developing striatum as a potential donor source for cell replacement therapy for Huntington disease. Cytotherapy 23(2), pp. 111-118. (10.1016/j.jcyt.2020.06.001)

2019

• Noakes, Z. et al. 2019. Human pluripotent stem cell-derived striatal interneurons: differentiation and maturation in vitro and in the rat brain. Stem Cell Reports 12(2), pp. 191-200. (10.1016/j.stemcr.2018.12.014)

2017

• Precious, S. V., Zietlow, R., Dunnett, S. B., Kelly, C. and Rosser, A. E. 2017. Is there a place for human fetal-derived stem cells for cell replacement therapy in Huntington's disease?. Neurochemistry International 106, pp. 114-121. (10.1016/j.neuint.2017.01.016)

2016

• Kelly, C., Johnson, I. G. and Morgan, M. Z. 2016. Oral cancer: exploring the stories in UK newspapers. British Dental Journal 221, pp. 247-250. (10.1038/sj.bdj.2016.643)
• Precious, S. V. et al. 2016. FoxP1 marks medium spiny neurons from precursors to maturity and is required for their differentiation. Experimental Neurology 282, pp. 9-18. (10.1016/j.expneurol.2016.05.002)
• Lelos, M., Morgan, R. J., Kelly, C., Torres, E. M., Rosser, A. E. and Dunnett, S. B. 2016. Amelioration of non-motor dysfunctions after transplantation of human dopamine neurons in a model of Parkinson's disease. Experimental Neurology 278, pp. 54-61. (10.1016/j.expneurol.2016.02.003)
• Precious, S. V., Kelly, C. M., Allen, N. D. and Rosser, A. E. 2016. Can manipulation of differentiation conditions eliminate proliferative cells from a population of ES cell-derived forebrain cells?. Neurogenesis 3(1), article number: e1127311. (10.1080/23262133.2015.1127311)

2015

• Straccia, M. et al. 2015. Quantitative high-throughput gene expression profiling of human striatal development to screen stem cell-derived medium spiny neurons. Molecular Therapy - Methods & Clinical Development 2, article number: 15030. (10.1038/mtm.2015.30)
• Roberton, V. H., Rosser, A. E. and Kelly, C. M. 2015. Neonatal desensitization for the study of regenerative medicine. Regenerative Medicine 10(3), pp. 265-274. (10.2217/rme.14.76)
• Arber, C. et al. 2015. Activin A directs striatal projection neuron differentiation of human pluripotent stem cells. Development 142(7), pp. 1375-1386. (10.1242/dev.117093)

2014

• Rinaldi, F. et al. 2014. Cross-regulation of Connexin43 and β-catenin influences differentiation of human neural progenitor cells. Cell Death and Disease 5(1), article number: e1017. (10.1038/cddis.2013.546)

2013

• Roberton, V. H., Evans, A. E., Harrison, D. J., Precious, S. V., Dunnett, S. B., Kelly, C. and Rosser, A. E. 2013. Is the adult mouse striatum a hostile host for neural transplant survival?. NeuroReport 24(18), pp. 1010-1015. (10.1097/WNR.0000000000000066)
• Heuer, A., Lelos, M. J., Kelly, C., Torres, E. M. and Dunnett, S. B. 2013. Dopamine-rich grafts alleviate deficits in contralateral response space induced by extensive dopamine depletion in rats. Experimental Neurology 247, pp. 485-495. (10.1016/j.expneurol.2013.01.020)
• Kelly, C., Battersby, A. and Rosser, A. E. 2013. Stem cell transplantation for neurodegenerative disease: a distant dream?. Aging Health 9(2), pp. 139-148. (10.2217/ahe.13.16)

2012

• Evans, A. E., Kelly, C., Precious, S. V. and Rosser, A. E. 2012. Molecular regulation of striatal development: a review. Anatomy Research International 2012, article number: 106529. (10.1155/2012/106529)
• Kelly, C., Roberton, V. H., Dunnett, S. B. and Rosser, A. E. 2012. Reply to "Neonatal desensitization does not universally prevent xenograft rejection". Nature Methods 9(9), pp. 858. (10.1038/nmeth.2144)
• Zietlow, R., Precious, S. V., Kelly, C., Dunnett, S. B. and Rosser, A. E. 2012. Long-term expansion of human foetal neural progenitors leads to reduced graft viability in the neonatal rat brain. Experimental Neurology 235(2), pp. 563-573. (10.1016/j.expneurol.2012.03.010)
• Smith, G. A. et al. 2012. L-dopa and graft-induced dyskinesia in the 6-OHDA-lesioned mouse [Abstract]. Cell Transplantation 21(4), pp. 792-792.

2011

• Rosser, A. E., Kelly, C. and Dunnett, S. B. 2011. Cell transplantation for Huntington's disease: practical and clinical considerations. Future Neurology 6(1), pp. 45-62. (10.2217/fnl.10.78)
• Hollins, A. J., Joy, S., Kelly, C. M., Battersby, A. A., Allen, N. D. and Rosser, A. E. 2011. Transplantation of differentiated human embryonic stem cells into a Huntington's Disease model: The challenges of generating neural cells suitable for replacement therapy in neurodegenerative disease. Cell Transplantation 20(4), pp. 563-564.
• Cordero-Llana, O. et al. 2011. Clusterin secreted by astrocytes enhances neuronal differentiation from human neural precursor cells. Cell Death and Differentiation 18(5), pp. 907-913. (10.1038/cdd.2010.169)
• Kelly, C. et al. 2011. Medical terminations of pregnancy: A viable source of tissue for cell replacement therapy for neurodegenerative disorders. Cell Transplantation 20(4), pp. 503-513. (10.3727/096368910X546580)

2009

• Kelly, C., Handley, O. J. and Rosser, A. 2009. Human trials for neurodegenerative disease. In: Scolding, N. J. and Gordon, D. eds. Neural Cell Transplantation: Methods and Protocols. Methods in Molecular Biology Vol. 549. New York: Humana Press, pp. 33-47., (10.1007/978-1-60327-931-4_3)
• Kelly, C. M. et al. 2009. Neonatal desensitization allows long-term survival of neural xenotransplants without immunosuppression. Nature Methods 6(4), pp. 271-273. (10.1038/nmeth.1308)
• Paynter, S. J., Andrews, K. J., Vinh, N., Kelly, C., Rosser, A. E., Amso, N. N. and Dunnett, S. B. 2009. Membrane permeability coefficients of murine primary neural brain cells in the presence of cryoprotectant. Cryoletters 29(1), pp. 84.
• Paynter, S. J., Andrews, K., Vinh, N., Kelly, C., Rosser, A. E., Amso, N. N. J. and Dunnett, S. B. 2009. Membrane permeability coefficients of murine primary neural brain cells in the presence of cryoprotectant. Cryobiology 58(3), pp. 308-314. (10.1016/j.cryobiol.2009.02.008)
• Kelly, C., Dunnett, S. B. and Rosser, A. E. 2009. Medium spiny neurons for transplantation in Huntington's disease. Biochemical Society Transactions 37(1), pp. 323-328. (10.1042/BST0370323)

2007

• Amso, N. N., Kelly, C., Penketh, R. and Precious, S. V. 2007. Striatal graft projections are influenced by donor cell type and not the immunogenic background. Brain 130(5), pp. 1317-29. (10.1093/brain/awm053)
• Kelly, C., Precious, S. V., Penketh, R., Amso, N. N., Dunnett, S. B. and Rosser, A. E. 2007. Striatal graft projections are influencd by donor cell type and not the immunogenic background. Brain 130, pp. 1317-1329. (10.1093/brain/awm053)
• Kelly, C., Precious, S. V., Penketh, R., Amso, N. N., Dunnett, S. B. and Rosser, A. E. 2007. Striatal graft projections are influenced by donor cell type and not the immunogenic background. Brain 130(5), pp. 1317-1329. (10.1093/brain/awm053)
• Joannides, A. J. et al. 2007. Environmental signals regulate lineage choice and temporal maturation of neural stem cells from human embryonic stem cells. Brain 130(5), pp. 1263-1275. (10.1093/brain/awm070)

2005

• Kelly, C., Tyers, P., Borg, M. t., Svendsen, C. N., Dunnett, S. B. and Rosser, A. E. 2005. EGF and FGF-2 responsiveness of rat and mouse neural precursors derived from the embryonic CNS. Brain Research Bulletin 68(1-2), pp. 83-94. (10.1016/j.brainresbull.2005.08.020)
• Kelly, C. M. 2005. Neural stem cells for cell replacement therapy in Huntington's disease. PhD Thesis, Cardiff University.