Dr Timothy Pickles

(e/fe)

BSc, MSc, PhD

2026

• Pickles, T. et al. 2026. Patient global assessment in rheumatoid arthritis: general health and disease activity are not interchangeable [Letter to the Editor]. Rheumatology 65 (7) keag376. (10.1093/rheumatology/keag376)
• Pickles, T. , Davies, J. and Choy, E. 2026. Thoughts of people living with rheumatoid arthritis on a weekly rheumatoid arthritis disease activity monitoring tool [Abstract]. Rheumatology (United Kingdom) 65 (Supp_2) keag121.312. (10.1093/rheumatology/keag121.312)
• Hopewell-Kelly, N. et al. 2026. Non-verbal methods for assessing grief and mental health in children and individuals with additional communication needs: A scoping review. Palliative Care & Social Practice 20 (10.1177/26323524251413281)
• Sydor, A. et al. 2026. Moral distress among nurses during the COVID ‐19 pandemic: A cross‐sectional survey. Nursing Open 13 (2) e70447. (10.1002/nop2.70447)

2025

• Pickles, T. et al. 2025. Assessing the content validity of patient reported outcome measure item pool for rheumatoid arthritis disease activity using cognitive interviews. Rheumatology 64 (12), pp.6176-6183. keaf421. (10.1093/rheumatology/keaf421)
• Pickles, T. et al. 2025. Patient reported outcome measures for rheumatoid arthritis disease activity: Rasch measurement theory to identify items and domains. Rheumatology 64 (9), pp.4902-4912. (10.1093/rheumatology/keaf189)
• Al-Yaseen, W. et al. 2025. Picture perfect: study protocol for assessing the accuracy, feasibility and acceptability of intraoral photographs captured by parents for remote dental screening in children – an observational mixed-methods study. BMJ Open 15 (9) e104769. (10.1136/bmjopen-2025-104769)
• Smith, S. L. et al., 2025. Validity and contributions to pain from the central aspects of pain questionnaire in rheumatoid arthritis. PAIN Reports 10 (4) e1295. (10.1097/PR9.0000000000001295)
• Griffiths, C. et al., 2025. The validation of the ‘CARe Burn Scale: Parent/Caregiver Form’—A patient reported outcome measure (PROM) using Rasch measurement theory (RMT) to assess quality of life for parents or caregivers supporting a child with a burn injury. European Burn Journal 6 (2) 22. (10.3390/ebj6020022)
• Pickles, T. and Ingram, J. R. 2025. Minimal important difference of pain numeric rating scale in patients with Hidradenitis suppurativa: results from THESEUS. British Journal of Dermatology 192 (4), pp.761-763. ljae486. (10.1093/bjd/ljae486)

2024

• Pattinson, R. et al. 2024. Measurement properties and interpretability of the Patient-Reported Impact of Dermatological Diseases (PRIDD) measure. British Journal of Dermatology 191 , pp.936-948. (10.1093/bjd/ljae267)
• Pattinson, R. et al. 2024. Further refinement of the Patient-Reported Impact of Dermatological Diseases (PRIDD) measure using classical test theory and item response theory. British Journal of Dermatology 190 (5), pp.718-728. ljad487. (10.1093/bjd/ljad487)
• Chapman, L. S. et al., 2024. Evolving and evaluating the OMERACT fellows program: insights and implications from OMERACT 2023 fellows. Seminars in Arthritis and Rheumatism 65 152391. (10.1016/j.semarthrit.2024.152391)
• Pickles, T. et al. 2024. Exploring the complexities of pain phenotypes: OMERACT 2023 chronic pain working group workshop. Seminars in Arthritis and Rheumatism 64 152342. (10.1016/j.semarthrit.2023.152342)
• Pickles, T. 2024. Patient-reported Outcome Measures for Rheumatoid Arthritis Symptom Severity: development of a computer adaptive test from an item bank using Rasch measurement theory (SOCRATES). PhD Thesis , Cardiff University.

2023

• Bisson, J. et al. 2023. Pragmatic randomised controlled trial of guided self-help versus individual cognitive behavioural therapy with a trauma focus for post-traumatic stress disorder (RAPID). Health Technology Assessment 27 26. (10.3310/YTQW8336)
• Pickles, T. et al. 2023. Patient reported outcome measures for rheumatoid arthritis disease activity: using Rasch measurement theory and cognitive interviewing to achieve more meaningful measurement [Abstract]. Presented at: ACR Convergence 2023 San Diego 10-15 November 2023. Vol. 75.Vol. Supp 9. Wiley. (10.1002/art.42700)
• Pickles, T. et al. 2023. P035 Patient-reported outcome measures for rheumatoid arthritis disease activity: using Rasch measurement theory to achieve more meaningful measurement. Rheumatology 62 (Supp 2)(10.1093/rheumatology/kead104.076)
• Withers, K. et al. 2023. Proceedings of the 6th National Patient Reported Outcome Measures (PROMs) Annual UK Research Virtual Conference, Bridgend, Wales 2022. Quality of Life Research 32 , pp.1-21. (10.1007/s11136-023-03353-w)
• Sauchelli, S. et al., 2023. Public attitudes towards the use of novel technologies in their future healthcare: a UK survey. BMC Medical Informatics and Decision Making 23 38. (10.1186/s12911-023-02118-2)
• Watts, T. et al. 2023. The ASSISTANCE STUDY: Moral distress and psychological wellbeing of nurses during the COVID-19 pandemic. Presented at: Royal College of Nursing International Nursing Research Conference Manchester University 6-8 September 2023.

2022

• Lau, T. M. M. et al. 2022. AZTEC—azithromycin therapy for prevention of chronic lung disease of prematurity: a statistical analysis plan for clinical outcomes. Trials 23 (1) 704. (10.1186/s13063-022-06604-2)
• Bisson, J. I. et al. 2022. Guided, internet based, cognitive behavioural therapy for post-traumatic stress disorder: pragmatic, multicentre, randomised controlled non-inferiority trial (RAPID). BMJ 377 e069405. (10.1136/bmj-2021-069405)
• Abbott, R. A. et al., 2022. Observational study to estimate the proportion of surgical site infection following excision of ulcerated skin tumours (OASIS study). Clinical and Experimental Dermatology 47 (5), pp.882-888. (10.1111/ced.15037)
• Pickles, T. et al. 2022. P089 Patient-reported outcome measures for rheumatoid arthritis disease activity: a systematic review following COSMIN guidelines. Presented at: British Society for Rheumatology Annual Conference 2022 Glasgow, Scotland 25-27 April 2022. Rheumatology Supplement 1. Vol. 61., pp.keac133.088. (10.1093/rheumatology/keac133.088)
• Pickles, T. et al. 2022. Patient reported outcome measures for rheumatoid arthritis disease activity: a systematic review following COSMIN guidelines. RMD Open 8 (1) e002093. (10.1136/rmdopen-2021-002093)
• Griffiths, C. et al., 2022. The CARe Burn Scale—Adult Form: Identifying the responsiveness and minimal important difference (MID) values of a Patient Reported Outcome Measure (PROM) to assess quality of life for adults with a burn injury. European Burn Journal 3 (1), pp.211-233. (10.3390/ebj3010019)
• Joshi, H. B. et al. 2022. Urinary stones and intervention quality of life (USIQoL): development and validation of a new core universal patient-reported outcome measure for urinary calculi. European Urology Focus 8 (1), pp.283-290. (10.1016/j.euf.2020.12.011)
• Pickering, D. , Pickles, T. and Shiress, T. 2022. A study protocol to develop the domains of an observational well-being scale (WEBS) for non-verbal children and young people with cerebral palsy from using the Innowalk.. Presented at: National Patient Reported Outcome Measures Online 14 - 15 June 2022.
• Watts, T. et al. 2022. Addressing moral distress among nurses after the COVID-19 emergency: The ASSISTANCE study. Presented at: Canopi Synposium Cardiff University May 2022.

2021

• Griffiths, C. et al., 2021. Testing the responsiveness of and defining minimal important difference (MID) values for the CARe burn scales: patient-reported outcome measures to assess quality of life for children and young people affected by burn injuries, and their parents/caregivers. European Burn Journal 2 (4), pp.249-280. (10.3390/ebj2040019)
• Pattinson, R. L. et al. 2021. Patient-reported outcome measures in dermatology: a systematic review. Acta Dermato-Venereologica 101 (9) adv00559. (10.2340/00015555-3884)
• McCarroll, Z. et al., 2021. Cost-effectiveness of home versus hospital management of children at onset of Type 1 Diabetes: The DECIDE randomised controlled trial. BMJ Open 11 (5) e043523. (10.1136/bmjopen-2020-043523)
• Bartlett, R. et al. 2021. Training results in increased practitioner confidence and identification of depression in people with low vision: a mixed methods study. Ophthalmic and Physiological Optics 41 (2), pp.316-330. (10.1111/opo.12788)
• Griffiths, C. et al., 2021. The development and validation of the CARe Burn Scale: Child Form: a parent-proxy-reported outcome measure assessing quality of life for children aged 8 years and under living with a burn injury. Quality of Life Research 30 , pp.239-250. (10.1007/s11136-020-02627-x)

2020

• Lowe, J. et al. 2020. Study protocol: azithromycin therapy for chronic lung disease of prematurity (AZTEC) - a randomised, placebo-controlled trial of azithromycin for the prevention of chronic lung disease of prematurity in preterm infants. BMJ Open 10 (10) e041528. (10.1136/bmjopen-2020-041528)
• Bisson, J. I. et al. 2020. Randomised controlled trial of multi-modular motion-assisted memory desensitization and reconsolidation (3MDR) for male military veterans with treatment-resistant post-traumatic stress disorder. Acta Psychiatrica Scandinavica 142 (2), pp.141-151. (10.1111/acps.13200)
• Stampalija, T. et al., 2020. Fetal cerebral Doppler changes and outcome in late preterm fetal growth restriction: prospective cohort study. Ultrasound in Obstetrics and Gynecology 56 (2), pp.173-181. (10.1002/uog.22125)
• Nollett, C. et al. 2020. Barriers to integrating routine depression screening into community low vision rehabilitation services: a mixed methods study. BMC Psychiatry 20 , pp.419. (10.1186/s12888-020-02805-8)

2019

• Nollett, C. et al. 2019. How do community-based eye care practitioners approach depression in patients with low vision? A mixed methods study. BMC Psychiatry 19 (1) 426. (10.1186/s12888-019-2387-x)
• Gregory, J. W. et al. 2019. Effectiveness of home or hospital initiation of treatment at diagnosis for children with type 1 diabetes (DECIDE trial): a multicentre individually randomised controlled trial. BMJ Open 9 e032317. (10.1136/bmjopen-2019-032317)
• Bosanquet, D. et al., 2019. Perineural local anaesthetic catheter after major lower limb amputation trial (PLACEMENT): results from a randomised controlled feasibility trial. BMJ Open 9 (11) e029233. (10.1136/bmjopen-2019-029233)
• Pickles, T. et al. 2019. Adaptive trial designs in rheumatology: Report from the OMERACT Special Interest Group. Journal of Rheumatology 46 (10), pp.1406-1408. jrheum.181054. (10.3899/jrheum.181054)
• Griffiths, C. et al., 2019. The development and validation of the CARe Burn Scale - Adult Form: a Patient Reported Outcome Measure (PROM) to assess quality of life for adults living with a burn injury. Journal of Burn Care and Research 40 (36), pp.312-326. (10.1093/jbcr/irz021)
• Morgan-Trimmer, S. et al. 2019. The acceptability of fluoride varnish and fissure sealant treatments in children aged 6-9 delivered in a school setting. Community Dental Health 36 (1), pp.33-38. (10.1922/CDH_4263Morgan-Trimmer06)

2018

• Cooksey, R. et al., 2018. Cardiovascular risk factors predicting cardiac events are different in patients with rheumatoid arthritis, psoriatic arthritis, and psoriasis. Seminars in Arthritis and Rheumatism 48 (3), pp.367-373. (10.1016/j.semarthrit.2018.03.005)
• Bosanquet, D. C. et al. 2018. Major lower limb amputation audit – introduction and implementation of a multimodal perioperative pain management guideline. British Journal of Pain 12 (4), pp.257-258. (10.1177/2049463718800736)
• Pickles, T. et al. 2018. Early phase and adaptive design clinical trials in rheumatoid arthritis: a systematic review of early phase trials. Rheumatology Advances in Practice 2 (2) rky045. (10.1093/rap/rky045)
• Butler, C. C. et al. 2018. Point-of-care urine culture for managing urinary tract infection in primary care: a randomised controlled trial of clinical and cost-effectiveness. British Journal of General Practice 68 (669), pp.e268-e278. (10.3399/bjgp18X695285)
• Nollett, C. et al. 2018. Pragmatic RAndomised controlled trial of a trauma-focused guided self-help Programme versus InDividual trauma-focused cognitive Behavioural therapy for post-traumatic stress disorder (RAPID): trial protocol. BMC Psychiatry 18 (1) 77. (10.1186/s12888-018-1665-3)
• Ingram, J. et al. 2018. Levels of wound calprotectin and other inflammatory biomarkers aid in deciding which patients with a diabetic foot ulcer need antibiotic therapy (INDUCE study). Diabetic Medicine 35 (2), pp.255-261. (10.1111/dme.13431)
• Alhaidari, T. et al., 2018. Feasibility and acceptability of text messaging to support antenatal healthcare in Iraqi pregnant women: a pilot study. Journal of Perinatal Medicine 46 (1), pp.67-74. (10.1515/jpm-2016-0127)

2017

• Butler, C. C. et al. 2017. Variations in presentation, management, and patient outcomes of urinary tract infection: a prospective four-country primary care observational cohort study. British Journal of General Practice 67 (665), pp.e830-e841. (10.3399/bjgp17X693641)
• Bosanquet, D. C. et al., 2017. Perineural local anaesthetic catheter after major lower limb amputation trial (PLACEMENT): study protocol for a randomised controlled pilot study. Trials 18 629. (10.1186/s13063-017-2357-x)
• White, J. et al. 2017. Adaptation of the ASSIST peer-led smoking intervention to deliver information from the Talk to FRANK drug education website (ASSIST+FRANK): a pilot cluster-randomised controlled trial. The Lancet 390 (S3), pp.S1. (10.1016/S0140-6736(17)32936-7)
• White, J. et al. 2017. Adapting the ASSIST model of informal peer-led intervention delivery to the Talk to FRANK drug prevention programme in UK secondary schools (ASSIST?+FRANK): intervention development, refinement and a pilot cluster randomised controlled trial. Public Health Research 5 (7), pp.1-126. (10.3310/phr05070)
• Hullegie, S. et al., 2017. Clinicians' interpretations of point of care urine culture versus laboratory culture results: analysis from the four-country POETIC trial of diagnosis of uncomplicated urinary tract infection in primary care. Family Practice 34 (4), pp.392-399. (10.1093/fampra/cmx009)
• Chestnutt, I. G. et al. 2017. Fissure seal or fluoride varnish? A randomised trial of their relative effectiveness. Journal of Dental Research 96 (7), pp.754-761. (10.1177/0022034517702094)
• Chestnutt, I. G. et al. 2017. Seal or Varnish? A randomised controlled trial to determine the relative cost and effectiveness of pit and fissure sealant and fluoride varnish in preventing dental decay. Health Technology Assessment 21 (21), pp.1-256. (10.3310/hta21210)
• Chalumeau, M. et al., 2017. Comparison of microbiological diagnosis of urinary tract infection in young children by routine health service laboratories and a research laboratory: diagnostic cohort study. PLoS ONE 12 (2) e0171113. (10.1371/journal.pone.0171113)

2016

• Hay, A. D. et al., 2016. Improving the diagnosis and treatment of urinary tract infection in young children in primary care: results from the DUTY prospective diagnostic cohort study. Annals of Family Medicine 14 (4), pp.325-336. (10.1370/afm.1954)
• Hay, A. D. et al., 2016. The Diagnosis of Urinary Tract infection in Young children (DUTY): a diagnostic prospective observational study to derive and validate a clinical algorithm for the diagnosis of urinary tract infection in children presenting to primary care with an acute illness. Health Technology Assessment 20 (51)(10.3310/hta20510)
• Butler, C. C. et al., 2016. Nappy pad urine samples for investigation and treatment of UTI in young children: the 'DUTY' prospective diagnostic cohort study. British Journal of General Practice 66 (648), pp.e516-e524. (10.3399/bjgp16X685873)
• Elwyn, G. et al., 2016. Supporting shared decision making using an Option Grid for osteoarthritis of the knee in an interface musculoskeletal clinic: a stepped wedge trial. Patient Education and Counseling 99 (4), pp.571-577. (10.1016/j.pec.2015.10.011)
• Atwan, A. et al., 2016. Oral fumaric acid esters for psoriasis: abridged Cochrane systematic review including GRADE assessments. British Journal of Dermatology 175 (5), pp.873-881. (10.1111/bjd.14676)
• Butler, C. C. et al., 2016. Empiric antibiotic treatment for urinary tract infection in preschool children: susceptibilities of urine sample isolates. Family Practice 33 (2), pp.127-132. (10.1093/fampra/cmv104)

2015

• Randell, E. et al. 2015. Eligibility for interventions, co-occurrence and risk factors for unhealthy behaviours in patients consulting for routine primary care: results from the Pre-Empt study. BMC Family Practice 16 133. (10.1186/s12875-015-0359-x)
• Gobat, N. H. et al. 2015. Measuring clinical skills in agenda-mapping (EAGL-I). Patient Education and Counseling 98 (10), pp.1214-1221. (10.1016/j.pec.2015.06.018)
• Al Ali, A. et al., 2015. The influence of snoring, mouth breathing and apnoea on facial morphology in late childhood: a three-dimensional study. BMJ Open 5 (9) e009027. (10.1136/bmjopen-2015-009027)
• Atwan, A. et al., 2015. Oral fumaric acid esters for psoriasis. Cochrane Database of Systematic Reviews (8) CD010497. (10.1002/14651858.CD010497.pub2)
• Butler, C. C. et al. 2015. Childhood urinary tract infection in primary care: a prospective observational study of prevalence, diagnosis, treatment, and recovery. British Journal of General Practice 65 (633), pp.e217-e223. (10.3399/bjgp15X684361)

2014

• Bates, J. et al., 2014. Point of care testing for urinary tract infection in primary care (POETIC): protocol for a randomised controlled trial of the clinical and cost effectiveness of FLEXICULT (TM) informed management of uncomplicated UTI in primary care. BMC Family Practice 15 , pp.-. 187. (10.1186/s12875-014-0187-4)
• Al Ali, A. et al., 2014. A three-dimensional analysis of the effect of atopy on face shape. European Journal of Orthodontics 36 (5), pp.506-511. (10.1093/ejo/cjs107)
• Haddad, N. S. et al., 2014. A feasibility study of mobile phone text messaging to support education and management of type 2 diabetes in Iraq. Diabetes Technology & Therapeutics 16 (7), pp.454-459. (10.1089/dia.2013.0272)
• Lowes, L. M. et al. 2014. Late-breaking abstract. [LB1 Delivering early care in diabetes evaluation: the DECIDE Study. Hospital versus home management at diagnosis in childhood diabetes: a comparison of psychological, social, physical and economic outcomes]. Diabetic Medicine 31 (s1), pp.184. (10.1111/dme.12408)
• Lowes, L. M. et al. 2014. Delivering early care in diabetes evaluation: the DECIDE study. Hospital versus home management at diagnosis in childhood diabetes: a comparison of psychological, social, physical and economic outcomes. Presented at: Diabetes UK Professional Conference 2014 Liverpool, UK 5-7 March 2014.
• Marrin, K. et al., 2014. Option Grids to facilitate shared decision making for patients with Osteoarthritis of the knee: protocol for a single site, efficacy trial. BMC Health Services Research 14 160. (10.1186/1472-6963-14-160)

2013

• Bates, J. et al., 2013. Effects of an optimised POCT guided diagnostic and treatment strategy for symptoms of uncomplicated UTI on use of appropriate antibiotics and uptake into primary care practice. [Abstract]. Trials 14 (S1), pp.-. P10. (10.1186/1745-6215-14-S1-P10)
• Pickles, T. et al. 2013. Rasch analysis of the PedsQL 3.0 diabetes module. [Abstract]. Trials 14 (S1) 040. (10.1186/1745-6215-14-S1-O40)
• Butler, C. C. et al. 2013. Training practitioners to deliver opportunistic multiple behaviour change counselling in primary care: a cluster randomised trial. BMJ 346 f1191. (10.1136/bmj.f1191)
• Edwards, A. G. et al. 2013. Personalised risk communication for informed decision making about taking screening tests. Cochrane Database of Systematic Reviews 2013 (2) CD001865. (10.1002/14651858.CD001865.pub3)
• Waldron, C. et al. 2013. Recruitment to diagnosis of urinary tract infections in young children (DUTY) study: an evaluation of the successful methods used in a primary care, prospective cohort study. [Abstract]. Trials 14 (S1), pp.-. P37. (10.1186/1745-6215-14-S1-P37)

2012

• Chestnutt, I. G. et al. 2012. Protocol for 'Seal or Varnish' (SoV) trial: A randomised controlled trial to measure the relative cost and effectiveness of pit and fissure sealants and fluoride varnish in preventing dental decay. BMC Oral Health 12 (1), pp.51-62. (10.1186/1472-6831-12-51)
• Robling, M. R. et al. 2012. The effect of the Talking Diabetes consulting skills intervention on glycaemic control and quality of life in children with type 1 diabetes: cluster randomised controlled trial (DEPICTED study). British Medical Journal 344 e2359. (10.1136/bmj.e2359)

2011

• Gregory, J. W. et al. 2011. Development and evaluation by a cluster randomised trial of a psychosocial intervention in children and teenagers experiencing diabetes: The DEPICTED study. Health Technology Assessment 15 (29), pp.1-202. (10.3310/hta15290)

2010

• Spanou, C. et al., 2010. Preventing disease through opportunistic, rapid engagement by primary care teams using behaviour change counselling (PRE-EMPT): protocol for a general practice-based cluster randomised trial. BMC Family Practice 11 (1), pp.69. (10.1186/1471-2296-11-69)