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Ryan Jones
Cydymaith Ymchwil
Ysgol y Biowyddorau
Trosolwyg
Rwy'n fyfyriwr PhD yn y Ganolfan Biomecaneg a Biobeirianneg Versus Arthritis ym Mhrifysgol Caerdydd, lle rwy'n ymchwilio i'r rhyngweithio rhwng biomecaneg a bioleg mewn meinweoedd ar y cyd. Fy uchelgais yw dod yn academydd sefydledig ym maes poen mewn cyflyrau cyhyrysgerbydol, trwy ddarparu ymchwil effaith uchel a datblygu dulliau newydd o fodelu mecanweithiau clefydau.
Rwyf wedi cyfrannu at ddatblygu'r model esgyrn osteocyte mecanyddol 3D gyda phwyslais arbennig ar ryngweithio esgyrn â'r nerfau ar lwytho mecanyddol a llid i ddatgelu mecanweithiau poen. Mae gen i brofiad helaeth o ymchwil mewn bioleg gyhyrysgerbydol sy'n canolbwyntio ar fecanweithiau moleciwlaidd sy'n ymwneud ag ymatebion mecanyddol ac llidiol gan egluro mecanweithiau signalau newydd sy'n rheoleiddio bioleg esgyrn a nerfau, i ddarparu targedau therapiwtig a diagnostig ar gyfer poen mewn clefyd cyhyrysgerbydol.
Rwy'n aelod o rwydwaith OAtech+ sy'n gweithio i wella cydweithio rhwng ymchwilwyr o Goleg y Gwyddorau Ffisegol a Pheirianneg ac yn cynrychioli ymchwilwyr ac yn hwyluso ymgysylltiad ar draws Prifysgol Caerdydd.
Cyhoeddiad
2024
- Jones, R., Gilbert, S. J., Christofides, S. R. and Mason, D. J. 2024. Osteocytes contribute to sex-specific differences in osteoarthritic pain. Frontiers in Endocrinology 15, article number: 1480274. (10.3389/fendo.2024.1480274)
- Gilbert, S. J., Jones, R., Egan, B. J., Bonnet, C. S., Evans, S. L. and Mason, D. J. 2024. Investigating mechanical and inflammatory pathological mechanisms in osteoarthritis using MSC-derived osteocyte-like cells in 3D. Frontiers in Endocrinology 15, article number: 1359052. (10.3389/fendo.2024.1359052)
2023
- Hamilton, R. et al. 2023. Measuring osteoarthritis knee nociception using physiological and movement response and a defined thermal stimulus: A proof-of-concept study.. Presented at: The International Combined Orthopaedic Research Societies (ICORS), World Congress of Orthopaedic Research, Edinburgh, UK, 7-9 September 2022Orthopaedic Proceedings, Vol. 105-B,. pp. 20-20., (10.1302/1358-992X.2023.8.020)
2021
- Hamilton, R., Holt, C., Jones, R., Shillabeer, D., Sparkes, V. and Mason, D. 2021. Measuring nociception in knee osteoarthritis using physiological and movement responses: a proof-of-concept study. Presented at: British Orthopaedic Research Society, Cardiff, UK, 13-14 September 2021.
Cynadleddau
- Hamilton, R. et al. 2023. Measuring osteoarthritis knee nociception using physiological and movement response and a defined thermal stimulus: A proof-of-concept study.. Presented at: The International Combined Orthopaedic Research Societies (ICORS), World Congress of Orthopaedic Research, Edinburgh, UK, 7-9 September 2022Orthopaedic Proceedings, Vol. 105-B,. pp. 20-20., (10.1302/1358-992X.2023.8.020)
- Hamilton, R., Holt, C., Jones, R., Shillabeer, D., Sparkes, V. and Mason, D. 2021. Measuring nociception in knee osteoarthritis using physiological and movement responses: a proof-of-concept study. Presented at: British Orthopaedic Research Society, Cardiff, UK, 13-14 September 2021.
Erthyglau
- Jones, R., Gilbert, S. J., Christofides, S. R. and Mason, D. J. 2024. Osteocytes contribute to sex-specific differences in osteoarthritic pain. Frontiers in Endocrinology 15, article number: 1480274. (10.3389/fendo.2024.1480274)
- Gilbert, S. J., Jones, R., Egan, B. J., Bonnet, C. S., Evans, S. L. and Mason, D. J. 2024. Investigating mechanical and inflammatory pathological mechanisms in osteoarthritis using MSC-derived osteocyte-like cells in 3D. Frontiers in Endocrinology 15, article number: 1359052. (10.3389/fendo.2024.1359052)