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Dr Angelo Amoroso
(e/fe)
Uwch Ddarlithydd mewn Cemeg Anorganig a Chyfarwyddwr Dysgu ac Addysgu
- Ar gael fel goruchwyliwr ôl-raddedig
Trosolwyg
Yn ddiweddar mae gennym ddiddordeb mewn datblygu asiantau delweddu newydd fel offer ymchwil ar gyfer mewnblaniadau bôn-gelloedd gan ddarparu'r gallu i ddelweddu, monitro ac olrhain tynged y celloedd trawsblannu'n uniongyrchol yn vivo.
Yn ystod yr ymchwil hon, bydd dyluniad, synthesis ac ymchwiliad i briodweddau ystod o ligands newydd yn cael eu gwneud, gydag eiddo fel sefydlogrwydd gwell, adweithedd bio-orthogonaidd ac eiddo electrogemegol / ffotoffisegol o ddiddordeb.
Am fwy o wybodaeth, cliciwch ar y tab 'Ymchwil' uchod.
Cyhoeddiad
2024
- Amoroso, A. J. and Pope, S. J. 2024. Lanthanides for luminescent and magnetic resonance imaging. In: Feng, L. and James, T. D. eds. Imaging Tools for Chemical Biology. Chemical Biology Royal Society of Chemistry, pp. 48-70., (10.1039/9781837673117-00048)
2022
- Al-Riyahee, A. A., Horton, P. N., Coles, S. J., Amoroso, A. J. and Pope, S. J. A. 2022. Ni(II), Cu(II) and Zn(II) complexes of functionalised thiosemicarbazone ligands: Syntheses and reactivity, characterization and structural studies. Polyhedron 225, article number: 116079. (10.1016/j.poly.2022.116079)
- Al-Riyahee, A. A. A., Horton, P. N., Coles, S. J., Berry, C., Horrocks, P. D., Pope, S. J. A. and Amoroso, A. J. 2022. N,N′-Substituted thioureas and their metal complexes: syntheses, structures and electronic properties. Dalton Transactions 51(9), pp. 3531-3545. (10.1039/D1DT04091J)
2019
- Al-Riyahee, A. A., Horton, P. N., Coles, S. J., Amoroso, A. J. and Pope, S. J. 2019. Syntheses, X-ray structures and characterisation of luminescent chromium(III) complexes incorporating 8-quinolinato ligands. Polyhedron 157, pp. 396. (10.1016/j.poly.2018.10.019)
2017
- Sathiyajith, C., Hallett, A. J., Amoroso, A. J. and Edwards, P. G. 2017. Dual modal imaging agents based on chromophore-bearing DTPA analogues. RSC Advances 7(61), pp. 38463-38470. (10.1039/C7RA06946D)
- Amoroso, A. J., Fallis, I. A. and Pope, S. J. A. 2017. Chelating agents for radiolanthanides: applications to imaging and therapy. Coordination Chemistry Reviews 340, pp. 198-219. (10.1016/j.ccr.2017.01.010)
2016
- Amoroso, A. J., Knight, J. C., Edwards, P. G., Singh, N. and Ward, B. D. 2016. Shaping and enforcing coordination spheres: probing the ability of tripodal ligands to favour trigonal prismatic geometry. Dalton Transactions 45(26), pp. 10630-10642. (10.1039/C6DT01165A)
- Amoroso, A. J., Saad, F., Knight, J. C. and Kariuki, B. 2016. Co-ordination behaviour of a novel tristhiourea tripodal ligand; structural variations in a series of transition metal complexes. Dalton Transactions 45(25), pp. 10280-10288. (10.1039/C6DT01148A)
- Jana, A. et al. 2016. Heteronuclear Ir(III)–Ln(III) luminescent complexes: small-molecule probes for dual modal imaging and oxygen sensing. Inorganic Chemistry 55(11), pp. 5623-5633. (10.1021/acs.inorgchem.6b00702)
- Stacey, O. J., Ward, B. D., Amoroso, A. J. and Pope, S. J. A. 2016. Near-IR luminescent lanthanide complexes with 1,8-diaminoanthraquinone-based chromophoric ligands. Dalton Transactions 45(15), pp. 6674-6681. (10.1039/C5DT04351D)
2015
- Stacey, O. J. et al. 2015. Water soluble, cyclometalated Pt(II)–Ln(III) conjugates towards novel bimodal imaging agents. Chemical Communications 51(61), pp. 12305-12308. (10.1039/C5CC02623G)
- Amoroso, A. J. and Pope, S. J. A. 2015. Using lanthanide ions in molecular bioimaging. Chemical Society Reviews 44(14), pp. 4723-4742. (10.1039/C4CS00293H)
- Jana, A., Baggaley, E., Amoroso, A. and Ward, M. D. 2015. A new ligand skeleton for imaging applications with d–f complexes: combined lifetime imaging and high relaxivity in an Ir/Gd dyad. Chemical Communications 51(42), pp. 8833-8836. (10.1039/C5CC02130H)
2014
- Foerster, C. et al. 2014. [64Cu]Cu-CryptTM – A novel cryptate for copper-64?. Nuclear Medicine and Biology 41(7), pp. 633. (10.1016/j.nucmedbio.2014.05.127)
- Foerster, C. et al. 2014. Synthesis, complex stability and small animal PET imaging of a novel 64Cu-labelled cryptand molecule. MedChemComm 5(7), pp. 958-962. (10.1039/c4md00174e)
- Hossain, G. M. G. and Amoroso, A. J. 2014. Bis[4-amino-N-(4-methylpyrimidin-2-yl-[kappa]N3)benzenesulfonamidato-[kappa]N](2,2'-bipyridine-[kappa]2N,N')mercury(II). Acta Crystallographica Section E - Structure Reports Online 70(4), pp. m127-m128. (10.1107/S1600536814004760)
2013
- Knight, J. C. et al. 2013. Synthesis, characterisation and evaluation of a novel copper-64 complex with selective uptake in EMT-6 cells under hypoxic conditions. Dalton Transactions 42(33), pp. 12005-12014. (10.1039/c3dt50960e)
- Saad, F. A., Knight, J. C., Kariuki, B. and Amoroso, A. J. 2013. Co-ordinative properties of a tripodal trisamide ligand with a capped octahedral preference. Dalton Transactions 42(41), pp. 14826-14835. (10.1039/c3dt51791h)
- Knight, J. C. et al. 2013. Synthesis, characterisation and radiopharmacological evaluation of a novel copper-64 complex derived from a tripodal N4S ligand [Poster presentation]. Journal of Labelled Compounds and Radiopharmaceuticals 56(S1), pp. S213.
2012
- Saad, F., Buurma, N. J., Amoroso, A. J., Knight, J. C. and Kariuki, B. . 2012. Co-ordination behaviour of a novel bisthiourea tripodal ligand: structural, spectroscopic and electrochemical properties of a series of transition metal complexes. Dalton Transactions 41(15), pp. 4608-4617. (10.1039/c2dt11732k)
- Hossain, G. M. G. and Amoroso, A. J. 2012. Bis[4-amino-N-(pyrimidin-2-yl-kappaN)benzenesulfonamidato-kappaN](4,4'-dimethyl-2,2'-bipyridine-kappa2N,N')cadmium dimethylformamide disolvate. Acta Crystallographica Section E Structure Reports Online 68(3), pp. m276-m277. (10.1107/S1600536812004412)
2011
- Knight, J. C., Prabaharan, R., Amoroso, A. J., Edwards, P. G. and Ooi, L. 2011. Synthesis and co-ordination chemistry of tris(picolyl-2-carboxyamido-6-pyridyl) methanol: A ligand with a strong preference for trigonal prismatic geometries. Polyhedron 31(1), pp. 457-462. (10.1016/j.poly.2011.09.040)
- Jones, J. E., Amoroso, A. J., Dorin, I. M., Parigi, G., Ward, B. D., Buurma, N. J. and Pope, S. J. A. 2011. Bimodal, dimetallic lanthanide complexes that bind to DNA: the nature of binding and its influence on water relaxivity. Chemical Communications 47(12), pp. 3374-3376. (10.1039/C1CC00111F)
- Knight, J. C., Prabaharan, R., Edwards, P. G. and Amoroso, A. J. 2011. Co-ordination of a new bis-terpyridine ligand with cupric perchlorate yielding a dinuclear M2L species. Journal of Molecular Structure 989(1-3), pp. 86-90. (10.1016/j.molstruc.2011.01.009)
2010
- Knight, J. C., Amoroso, A. J., Edwards, P. G., Prabaharan, R. and Singh, N. 2010. The co-ordination chemistry of bis(2,2′-bipyrid-6′-yl)ketone with first row transition metals: the reversible interconversion of a mononuclear complex and a dinuclear hemiketal containing species. Dalton Transactions 39(38), pp. 8925-8936. (10.1039/c0dt00344a)
- Amoroso, A. J., Banu, A., Coogan, M. P., Edwards, P. G., Hossain, G. and Malik, K. M. A. 2010. Functionalisation of terpyridine complexes containing the Re(CO)3+ moiety. Dalton Transactions 39(30), pp. 6993-7003. (10.1039/c0dt00174k)
- Knight, J. C., Prabaharan, R., Ward, B. D., Amoroso, A. J., Edwards, P. G. and Kariuki, B. 2010. A facile one-pot synthesis of a new cryptand via a Pd(II)-catalysed carbonylation reaction. Dalton Transactions 39(42), pp. 10031-10033. (10.1039/C0DT01205J)
- Andrews, M., Amoroso, A. J., Harding, L. P. and Pope, S. J. A. 2010. Responsive, di-metallic lanthanide complexes of a piperazine-bridged bis-macrocyclic ligand: modulation of visible luminescence and proton relaxivity. Dalton Transactions 39(14), pp. 3407-3411. (10.1039/b923988j)
- Knight, J. C., Alvarez, S., Amoroso, A. J., Edwards, P. G. and Singh, N. 2010. A novel bipyridine-based hexadentate tripodal framework with a strong preference for trigonal prismatic co-ordination geometries. Dalton Transactions 39(16), pp. 3870-3883. (10.1039/b924651g)
- Fernández-Moreira, V. et al. 2010. Uptake and localisation of rhenium fac-tricarbonyl polypyridyls in fluorescent cell imaging experiments. Organic and Biomolecular Chemistry 8(17), pp. 3888-3901. (10.1039/c004610h)
2009
- Amoroso, A. J. et al. 2009. The synthesis and coordination chemistry of a tris-8-aminoquinoline tripodal ligand. Dalton Transactions(39), pp. 8356-8362. (10.1039/b909122j)
- Knight, J. C., Saad, F., Amoroso, A. J., Kariuki, B. and Coles, S. J. 2009. rac-N-{6-[Bromo(hydroxy)methyl]-2-pyridyl}pivalamide. Acta Crystallographica Section E - Structure Reports Online 65(3), article number: O647. (10.1107/S1600536809006795)
- Echeverria, J., Cremades, E., Amoroso, A. J. and Alvarez, S. 2009. Jahn-Teller distortions of six-coordinate CuII compounds: cis or trans?. Chemical Communications 2009(28), pp. 4242-4244. (10.1039/b903867a)
2008
- Amoroso, A. J. et al. 2008. 3-Chloromethylpyridyl bipyridine fac-tricarbonyl rhenium: a thiol-reactive luminophore for fluorescence microscopy accumulates in mitochondria. New Journal of Chemistry 32(7), pp. 1097-1102. (10.1039/b802215a)
- Amoroso, A. J. et al. 2008. The synthesis and structure of terpyridine-N-oxide complexes of copper(II) perchlorate. Dalton Transactions(4), pp. 506-513. (10.1039/b713444d)
2007
- Amoroso, A. J. et al. 2007. Rhenium fac tricarbonyl bisimine complexes: biologically useful fluorochromes for cell imaging applications. Chemical Communications(29), pp. 3066-3068. (10.1039/b706657k)
Articles
- Al-Riyahee, A. A., Horton, P. N., Coles, S. J., Amoroso, A. J. and Pope, S. J. A. 2022. Ni(II), Cu(II) and Zn(II) complexes of functionalised thiosemicarbazone ligands: Syntheses and reactivity, characterization and structural studies. Polyhedron 225, article number: 116079. (10.1016/j.poly.2022.116079)
- Al-Riyahee, A. A. A., Horton, P. N., Coles, S. J., Berry, C., Horrocks, P. D., Pope, S. J. A. and Amoroso, A. J. 2022. N,N′-Substituted thioureas and their metal complexes: syntheses, structures and electronic properties. Dalton Transactions 51(9), pp. 3531-3545. (10.1039/D1DT04091J)
- Al-Riyahee, A. A., Horton, P. N., Coles, S. J., Amoroso, A. J. and Pope, S. J. 2019. Syntheses, X-ray structures and characterisation of luminescent chromium(III) complexes incorporating 8-quinolinato ligands. Polyhedron 157, pp. 396. (10.1016/j.poly.2018.10.019)
- Sathiyajith, C., Hallett, A. J., Amoroso, A. J. and Edwards, P. G. 2017. Dual modal imaging agents based on chromophore-bearing DTPA analogues. RSC Advances 7(61), pp. 38463-38470. (10.1039/C7RA06946D)
- Amoroso, A. J., Fallis, I. A. and Pope, S. J. A. 2017. Chelating agents for radiolanthanides: applications to imaging and therapy. Coordination Chemistry Reviews 340, pp. 198-219. (10.1016/j.ccr.2017.01.010)
- Amoroso, A. J., Knight, J. C., Edwards, P. G., Singh, N. and Ward, B. D. 2016. Shaping and enforcing coordination spheres: probing the ability of tripodal ligands to favour trigonal prismatic geometry. Dalton Transactions 45(26), pp. 10630-10642. (10.1039/C6DT01165A)
- Amoroso, A. J., Saad, F., Knight, J. C. and Kariuki, B. 2016. Co-ordination behaviour of a novel tristhiourea tripodal ligand; structural variations in a series of transition metal complexes. Dalton Transactions 45(25), pp. 10280-10288. (10.1039/C6DT01148A)
- Jana, A. et al. 2016. Heteronuclear Ir(III)–Ln(III) luminescent complexes: small-molecule probes for dual modal imaging and oxygen sensing. Inorganic Chemistry 55(11), pp. 5623-5633. (10.1021/acs.inorgchem.6b00702)
- Stacey, O. J., Ward, B. D., Amoroso, A. J. and Pope, S. J. A. 2016. Near-IR luminescent lanthanide complexes with 1,8-diaminoanthraquinone-based chromophoric ligands. Dalton Transactions 45(15), pp. 6674-6681. (10.1039/C5DT04351D)
- Stacey, O. J. et al. 2015. Water soluble, cyclometalated Pt(II)–Ln(III) conjugates towards novel bimodal imaging agents. Chemical Communications 51(61), pp. 12305-12308. (10.1039/C5CC02623G)
- Amoroso, A. J. and Pope, S. J. A. 2015. Using lanthanide ions in molecular bioimaging. Chemical Society Reviews 44(14), pp. 4723-4742. (10.1039/C4CS00293H)
- Jana, A., Baggaley, E., Amoroso, A. and Ward, M. D. 2015. A new ligand skeleton for imaging applications with d–f complexes: combined lifetime imaging and high relaxivity in an Ir/Gd dyad. Chemical Communications 51(42), pp. 8833-8836. (10.1039/C5CC02130H)
- Foerster, C. et al. 2014. [64Cu]Cu-CryptTM – A novel cryptate for copper-64?. Nuclear Medicine and Biology 41(7), pp. 633. (10.1016/j.nucmedbio.2014.05.127)
- Foerster, C. et al. 2014. Synthesis, complex stability and small animal PET imaging of a novel 64Cu-labelled cryptand molecule. MedChemComm 5(7), pp. 958-962. (10.1039/c4md00174e)
- Hossain, G. M. G. and Amoroso, A. J. 2014. Bis[4-amino-N-(4-methylpyrimidin-2-yl-[kappa]N3)benzenesulfonamidato-[kappa]N](2,2'-bipyridine-[kappa]2N,N')mercury(II). Acta Crystallographica Section E - Structure Reports Online 70(4), pp. m127-m128. (10.1107/S1600536814004760)
- Knight, J. C. et al. 2013. Synthesis, characterisation and evaluation of a novel copper-64 complex with selective uptake in EMT-6 cells under hypoxic conditions. Dalton Transactions 42(33), pp. 12005-12014. (10.1039/c3dt50960e)
- Saad, F. A., Knight, J. C., Kariuki, B. and Amoroso, A. J. 2013. Co-ordinative properties of a tripodal trisamide ligand with a capped octahedral preference. Dalton Transactions 42(41), pp. 14826-14835. (10.1039/c3dt51791h)
- Knight, J. C. et al. 2013. Synthesis, characterisation and radiopharmacological evaluation of a novel copper-64 complex derived from a tripodal N4S ligand [Poster presentation]. Journal of Labelled Compounds and Radiopharmaceuticals 56(S1), pp. S213.
- Saad, F., Buurma, N. J., Amoroso, A. J., Knight, J. C. and Kariuki, B. . 2012. Co-ordination behaviour of a novel bisthiourea tripodal ligand: structural, spectroscopic and electrochemical properties of a series of transition metal complexes. Dalton Transactions 41(15), pp. 4608-4617. (10.1039/c2dt11732k)
- Hossain, G. M. G. and Amoroso, A. J. 2012. Bis[4-amino-N-(pyrimidin-2-yl-kappaN)benzenesulfonamidato-kappaN](4,4'-dimethyl-2,2'-bipyridine-kappa2N,N')cadmium dimethylformamide disolvate. Acta Crystallographica Section E Structure Reports Online 68(3), pp. m276-m277. (10.1107/S1600536812004412)
- Knight, J. C., Prabaharan, R., Amoroso, A. J., Edwards, P. G. and Ooi, L. 2011. Synthesis and co-ordination chemistry of tris(picolyl-2-carboxyamido-6-pyridyl) methanol: A ligand with a strong preference for trigonal prismatic geometries. Polyhedron 31(1), pp. 457-462. (10.1016/j.poly.2011.09.040)
- Jones, J. E., Amoroso, A. J., Dorin, I. M., Parigi, G., Ward, B. D., Buurma, N. J. and Pope, S. J. A. 2011. Bimodal, dimetallic lanthanide complexes that bind to DNA: the nature of binding and its influence on water relaxivity. Chemical Communications 47(12), pp. 3374-3376. (10.1039/C1CC00111F)
- Knight, J. C., Prabaharan, R., Edwards, P. G. and Amoroso, A. J. 2011. Co-ordination of a new bis-terpyridine ligand with cupric perchlorate yielding a dinuclear M2L species. Journal of Molecular Structure 989(1-3), pp. 86-90. (10.1016/j.molstruc.2011.01.009)
- Knight, J. C., Amoroso, A. J., Edwards, P. G., Prabaharan, R. and Singh, N. 2010. The co-ordination chemistry of bis(2,2′-bipyrid-6′-yl)ketone with first row transition metals: the reversible interconversion of a mononuclear complex and a dinuclear hemiketal containing species. Dalton Transactions 39(38), pp. 8925-8936. (10.1039/c0dt00344a)
- Amoroso, A. J., Banu, A., Coogan, M. P., Edwards, P. G., Hossain, G. and Malik, K. M. A. 2010. Functionalisation of terpyridine complexes containing the Re(CO)3+ moiety. Dalton Transactions 39(30), pp. 6993-7003. (10.1039/c0dt00174k)
- Knight, J. C., Prabaharan, R., Ward, B. D., Amoroso, A. J., Edwards, P. G. and Kariuki, B. 2010. A facile one-pot synthesis of a new cryptand via a Pd(II)-catalysed carbonylation reaction. Dalton Transactions 39(42), pp. 10031-10033. (10.1039/C0DT01205J)
- Andrews, M., Amoroso, A. J., Harding, L. P. and Pope, S. J. A. 2010. Responsive, di-metallic lanthanide complexes of a piperazine-bridged bis-macrocyclic ligand: modulation of visible luminescence and proton relaxivity. Dalton Transactions 39(14), pp. 3407-3411. (10.1039/b923988j)
- Knight, J. C., Alvarez, S., Amoroso, A. J., Edwards, P. G. and Singh, N. 2010. A novel bipyridine-based hexadentate tripodal framework with a strong preference for trigonal prismatic co-ordination geometries. Dalton Transactions 39(16), pp. 3870-3883. (10.1039/b924651g)
- Fernández-Moreira, V. et al. 2010. Uptake and localisation of rhenium fac-tricarbonyl polypyridyls in fluorescent cell imaging experiments. Organic and Biomolecular Chemistry 8(17), pp. 3888-3901. (10.1039/c004610h)
- Amoroso, A. J. et al. 2009. The synthesis and coordination chemistry of a tris-8-aminoquinoline tripodal ligand. Dalton Transactions(39), pp. 8356-8362. (10.1039/b909122j)
- Knight, J. C., Saad, F., Amoroso, A. J., Kariuki, B. and Coles, S. J. 2009. rac-N-{6-[Bromo(hydroxy)methyl]-2-pyridyl}pivalamide. Acta Crystallographica Section E - Structure Reports Online 65(3), article number: O647. (10.1107/S1600536809006795)
- Echeverria, J., Cremades, E., Amoroso, A. J. and Alvarez, S. 2009. Jahn-Teller distortions of six-coordinate CuII compounds: cis or trans?. Chemical Communications 2009(28), pp. 4242-4244. (10.1039/b903867a)
- Amoroso, A. J. et al. 2008. 3-Chloromethylpyridyl bipyridine fac-tricarbonyl rhenium: a thiol-reactive luminophore for fluorescence microscopy accumulates in mitochondria. New Journal of Chemistry 32(7), pp. 1097-1102. (10.1039/b802215a)
- Amoroso, A. J. et al. 2008. The synthesis and structure of terpyridine-N-oxide complexes of copper(II) perchlorate. Dalton Transactions(4), pp. 506-513. (10.1039/b713444d)
- Amoroso, A. J. et al. 2007. Rhenium fac tricarbonyl bisimine complexes: biologically useful fluorochromes for cell imaging applications. Chemical Communications(29), pp. 3066-3068. (10.1039/b706657k)
Book sections
- Amoroso, A. J. and Pope, S. J. 2024. Lanthanides for luminescent and magnetic resonance imaging. In: Feng, L. and James, T. D. eds. Imaging Tools for Chemical Biology. Chemical Biology Royal Society of Chemistry, pp. 48-70., (10.1039/9781837673117-00048)
- Knight, J. C. et al. 2013. Synthesis, characterisation and evaluation of a novel copper-64 complex with selective uptake in EMT-6 cells under hypoxic conditions. Dalton Transactions 42(33), pp. 12005-12014. (10.1039/c3dt50960e)
- Jones, J. E., Amoroso, A. J., Dorin, I. M., Parigi, G., Ward, B. D., Buurma, N. J. and Pope, S. J. A. 2011. Bimodal, dimetallic lanthanide complexes that bind to DNA: the nature of binding and its influence on water relaxivity. Chemical Communications 47(12), pp. 3374-3376. (10.1039/C1CC00111F)
- Echeverria, J., Cremades, E., Amoroso, A. J. and Alvarez, S. 2009. Jahn-Teller distortions of six-coordinate CuII compounds: cis or trans?. Chemical Communications 2009(28), pp. 4242-4244. (10.1039/b903867a)
- Amoroso, A. J. et al. 2008. 3-Chloromethylpyridyl bipyridine fac-tricarbonyl rhenium: a thiol-reactive luminophore for fluorescence microscopy accumulates in mitochondria. New Journal of Chemistry 32(7), pp. 1097-1102. (10.1039/b802215a)
Ymchwil
- Datblygu cymhlethdodau fflwroleuol iawn ar gyfer tagiau biolegol neu fel synwyryddion cemegol.
- Dylunio a synthesis o ligands sy'n addas ar gyfer adeiladu asiantau delweddu. Ar hyn o bryd rydym yn cyfosod adweithyddion a fydd yn dangos ymddygiad newid rhydocs / cemegol gan gynhyrchu adweithyddion diagnostig effeithiol.
- Newidiadau ligand gan arwain at stereochemistry ac adweithedd wedi'i addasu. Yn sail i'n hymchwil gymhwysol mae'r pwnc diddorol o sut y gall newidiadau syml i arae ligand effeithio'n fawr ar dopoleg ac adweithedd prehaps.
Yn ddiweddar mae gennym ddiddordeb mewn datblygu asiantau delweddu newydd fel offer ymchwil ar gyfer mewnblaniadau bôn-gelloedd. Mae'r defnydd o fôn-gelloedd ar gyfer therapïau cellog yn faes ymchwil sy'n dangos addewid gwych ar gyfer lliniaru ac o bosibl atgyweirio ystod o gyflyrau. Fodd bynnag, cyfyngiad mawr ar ymchwil mewn trawsblaniad yw'r anhawster i ddelweddu, monitro ac olrhain tynged y celloedd trawsblannu'n uniongyrchol yn vivo. Gwnaed rhywfaint o gynnydd i olrhain amrywiaeth o fathau o impiadau in vivo gan ddefnyddio PET. Mewn ymgais i ddatblygu cenhedlaeth newydd o asiantau PET y gellir eu defnyddio ar gyfer delweddu vivo o atgyweirio meinweoedd rydym wedi datblygu methodolegau i gydlynu a phuro cymhlethdodau isotopau metel hirhoedlog sy'n caniatáu delweddu dros gyfnodau hir, gan ddarparu offer ymchwil newydd yn y maes ymchwil hwn.
I gael rhagor o wybodaeth am brosiectau penodol gyda Dr Angelo Amoroso, adolygwch adran synthesis moleciwlaidd ein themâu prosiect ymchwil.
Addysgu
CH5202 - Adweithedd ac Eiddo'r Cynhwysion a'u Cyfansoddion
CH2301 - Hyfforddiant mewn Dulliau Ymchwil
CH4302 - Cemeg Organometalig a Chydlynu Uwch
CH3403 - Bio-ddelweddu Cymwysiadau Cemeg Cydgysylltu
Gellir dod o hyd i fanylion modiwlau yn y darganfyddwr cyrsiau.
Bywgraffiad
PhD, University of Cambridge (1992, B. F. G. Johnson and J. Lewis, synthesis of high nuclearity osmium carbonyl clusters). Postdoctoral Research Fellow, Bristol (1992-1995, J. A. McCleverty and M. D. Ward, synthesis and properties of Mo(NO) species). Postdoctoral Research Fellow, University of Utah (1995-1997, J. A. Gladysz, synthesis and properties of Re(NO) species linked by polyacetylene fragments). Postdoctoral Research Fellow, University of Nottingham (1997-1998, M. SchrÃder, modelling Ni/Fe hydrogenases). Appointed Lecturer in Inorganic Chemistry, Cardiff, 1998.
Contact Details
Themâu ymchwil
Arbenigeddau
- Cemeg anorganig