Darren Cameron
Cydymaith Ymchwil, Is-adran Meddygaeth Seicolegol a Niwrowyddorau Clinigol
Cyhoeddiad
2024
- Tume, C. E., Chick, S. L., Holmans, P. A., Rees, E., O'Donovan, M. C., Cameron, D. and Bray, N. J. 2024. Genetic implication of specific glutamatergic neurons of the prefrontal cortex in the pathophysiology of schizophrenia. Biological Psychiatry 4(5), article number: 100345. (10.1016/j.bpsgos.2024.100345)
- Cameron, D. et al. 2024. Genetic implication of prenatal GABAergic and cholinergic neuron development in susceptibility to schizophrenia. Schizophrenia Bulletin Open 50(5), pp. 1171-1184. (10.1093/schbul/sbae083)
2023
- Cameron, D. et al. 2023. Single nuclei RNA sequencing of 5 regions of the human prenatal brain implicates developing neuron populations in genetic risk for schizophrenia. Biological Psychiatry 93, pp. 157-166. (10.1016/j.biopsych.2022.06.033)
2021
- Kouakou, M., Cameron, D., Hannon, E., Dempster, E. L., Mill, J., Hill, M. J. and Bray, N. 2021. Sites of active gene regulation in the prenatal frontal cortex and their role in neuropsychiatric disorders. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 186(6), pp. 376-388. (10.1002/ajmg.b.32877)
2019
- Cameron, D., Blake, D. J., Bray, N. J. and Hill, M. J. 2019. Transcriptional changes following cellular knockdown of the schizophrenia risk gene SETD1A are enriched for common variant association with the disorder. Molecular Neuropsychiatry 5(2), pp. 109-114. (10.1159/000497181)
- Cameron, D. 2019. Gene regulation in microglia and genetic risk for complex brain disorders. PhD Thesis, Cardiff University.
2018
- Pardinas, A. F. et al. 2018. Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection. Nature Genetics 50, pp. 381-389. (10.1038/s41588-018-0059-2)
- Tansey, K. E., Cameron, D. and Hill, M. J. 2018. Genetic risk for Alzheimer's disease is concentrated in specific macrophage and microglial transcriptional networks. Genome Medicine 10, article number: 14. (10.1186/s13073-018-0523-8)
2017
- Clifton, N., Cameron, D., Trent, S., Sykes, L. H., Thomas, K. L. and Hall, J. 2017. Hippocampal regulation of postsynaptic density Homer1 by associative learning. Neural Plasticity 2017, article number: 5959182. (10.1155/2017/5959182)
2016
- Pardinas, A. et al. 2016. Common schizophrenia alleles are enriched in mutation-intolerant genes and maintained by background selection. [Online]. bioRxiv. (10.1101/068593) Available at: http://dx.doi.org/10.1101/068593
Erthyglau
- Tume, C. E., Chick, S. L., Holmans, P. A., Rees, E., O'Donovan, M. C., Cameron, D. and Bray, N. J. 2024. Genetic implication of specific glutamatergic neurons of the prefrontal cortex in the pathophysiology of schizophrenia. Biological Psychiatry 4(5), article number: 100345. (10.1016/j.bpsgos.2024.100345)
- Cameron, D. et al. 2024. Genetic implication of prenatal GABAergic and cholinergic neuron development in susceptibility to schizophrenia. Schizophrenia Bulletin Open 50(5), pp. 1171-1184. (10.1093/schbul/sbae083)
- Cameron, D. et al. 2023. Single nuclei RNA sequencing of 5 regions of the human prenatal brain implicates developing neuron populations in genetic risk for schizophrenia. Biological Psychiatry 93, pp. 157-166. (10.1016/j.biopsych.2022.06.033)
- Kouakou, M., Cameron, D., Hannon, E., Dempster, E. L., Mill, J., Hill, M. J. and Bray, N. 2021. Sites of active gene regulation in the prenatal frontal cortex and their role in neuropsychiatric disorders. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 186(6), pp. 376-388. (10.1002/ajmg.b.32877)
- Cameron, D., Blake, D. J., Bray, N. J. and Hill, M. J. 2019. Transcriptional changes following cellular knockdown of the schizophrenia risk gene SETD1A are enriched for common variant association with the disorder. Molecular Neuropsychiatry 5(2), pp. 109-114. (10.1159/000497181)
- Pardinas, A. F. et al. 2018. Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection. Nature Genetics 50, pp. 381-389. (10.1038/s41588-018-0059-2)
- Tansey, K. E., Cameron, D. and Hill, M. J. 2018. Genetic risk for Alzheimer's disease is concentrated in specific macrophage and microglial transcriptional networks. Genome Medicine 10, article number: 14. (10.1186/s13073-018-0523-8)
- Clifton, N., Cameron, D., Trent, S., Sykes, L. H., Thomas, K. L. and Hall, J. 2017. Hippocampal regulation of postsynaptic density Homer1 by associative learning. Neural Plasticity 2017, article number: 5959182. (10.1155/2017/5959182)
Gosodiad
- Cameron, D. 2019. Gene regulation in microglia and genetic risk for complex brain disorders. PhD Thesis, Cardiff University.
Gwefannau
- Pardinas, A. et al. 2016. Common schizophrenia alleles are enriched in mutation-intolerant genes and maintained by background selection. [Online]. bioRxiv. (10.1101/068593) Available at: http://dx.doi.org/10.1101/068593
Bywgraffiad
Rwy'n gweithio ar ddadansoddi a dehongli setiau data genomeg un gell yn bennaf ar gyfer integreiddio â data o anhwylder niwroseiciatrig GWAS i nodi'r mathau o gelloedd a'r mecanweithiau moleciwlaidd sy'n cyfryngu risg ar gyfer anhwylderau ymennydd cymhleth.
Contact Details
CameronD@caerdydd.ac.uk
Adeilad Hadyn Ellis, Ystafell 2.01 - Desg 46, Heol Maendy, Caerdydd, CF24 4HQ
Adeilad Hadyn Ellis, Ystafell 2.01 - Desg 46, Heol Maendy, Caerdydd, CF24 4HQ