Dr Sophie Cook
Timau a rolau for Sophie Cook
Cymrawd Ymchwil
Ysgol y Biowyddorau
Cyhoeddiad
2025
- Best, H. L., Cook, S. R., Waller-Evans, H. and Lloyd-Evans, E. 2025. Niemann-Pick C-like endo-lysosomal dysfunction in DHDDS patient cells, a congenital disorder of glycosylation, can be treated with miglustat. International Journal of Molecular Sciences 26(4), article number: 1471. (10.3390/ijms26041471)
2023
- Cook, S. R. and Lloyd-Evans, E. 2023. Comparing the lysosomal biotoxicity of iron oxide nanoparticles for improved lysosomal purification. Presented at: 19th Annual WORLDSymposiumTM, Orlando, Florida, 21-26 February 2023, Vol. 138. Vol. 2. Elsevier pp. 28-29., (10.1016/j.ymgme.2022.107062)
- Cook, S. R., Kirkham, E. D., Best, H., Waller-Evans, H., Serpi, M., Pertusati, F. and Lloyd-Evans, E. 2023. Investigating lysosomal and cellular phenotypes of the lysosomal disorder cystinosis. Presented at: 19th Annual WORLDSymposium™ 2023, Orlando, Florida, 21-26 February 2023, Vol. 138. Vol. 2. Elsevier pp. 28-28., (10.1016/j.ymgme.2022.107061)
2022
- Cook, S. 2022. Investigating the impact of metallic nanoparticles on biological systems and lysosomal function. PhD Thesis, Cardiff University.
2020
- Cook, S. R. et al. 2020. Visualisation of cholesterol and ganglioside GM1 in zebrafish models of Niemann-Pick type C disease and Smith-Lemli-Opitz syndrome using light sheet microscopy. Histochemistry and Cell Biology 154, pp. 565-578. (10.1007/s00418-020-01925-2)
- Cook, S. R. et al. 2020. Detrimental effect of zwitterionic buffers on lysosomal homeostasis in cell lines and iPSC-derived neurons. AMRC Open Research 2, article number: 21. (10.12688/amrcopenres.12903.1)
Articles
- Best, H. L., Cook, S. R., Waller-Evans, H. and Lloyd-Evans, E. 2025. Niemann-Pick C-like endo-lysosomal dysfunction in DHDDS patient cells, a congenital disorder of glycosylation, can be treated with miglustat. International Journal of Molecular Sciences 26(4), article number: 1471. (10.3390/ijms26041471)
- Cook, S. R. et al. 2020. Visualisation of cholesterol and ganglioside GM1 in zebrafish models of Niemann-Pick type C disease and Smith-Lemli-Opitz syndrome using light sheet microscopy. Histochemistry and Cell Biology 154, pp. 565-578. (10.1007/s00418-020-01925-2)
- Cook, S. R. et al. 2020. Detrimental effect of zwitterionic buffers on lysosomal homeostasis in cell lines and iPSC-derived neurons. AMRC Open Research 2, article number: 21. (10.12688/amrcopenres.12903.1)
Conferences
- Cook, S. R. and Lloyd-Evans, E. 2023. Comparing the lysosomal biotoxicity of iron oxide nanoparticles for improved lysosomal purification. Presented at: 19th Annual WORLDSymposiumTM, Orlando, Florida, 21-26 February 2023, Vol. 138. Vol. 2. Elsevier pp. 28-29., (10.1016/j.ymgme.2022.107062)
- Cook, S. R., Kirkham, E. D., Best, H., Waller-Evans, H., Serpi, M., Pertusati, F. and Lloyd-Evans, E. 2023. Investigating lysosomal and cellular phenotypes of the lysosomal disorder cystinosis. Presented at: 19th Annual WORLDSymposium™ 2023, Orlando, Florida, 21-26 February 2023, Vol. 138. Vol. 2. Elsevier pp. 28-28., (10.1016/j.ymgme.2022.107061)
Thesis
- Cook, S. 2022. Investigating the impact of metallic nanoparticles on biological systems and lysosomal function. PhD Thesis, Cardiff University.