Dr Sophie Cook
Teams and roles for Sophie Cook
Research Fellow
School of Biosciences
Publication
2025
- Best, H. L. et al. 2025. Niemann-Pick C-like endo-lysosomal dysfunction in DHDDS patient cells, a congenital disorder of glycosylation, can be treated with miglustat. International Journal of Molecular Sciences 26 (4) 1471. (10.3390/ijms26041471)
2023
- Cook, S. R. et al. 2023. Investigating lysosomal and cellular phenotypes of the lysosomal disorder cystinosis. Presented at: 19th Annual WORLDSymposium™ 2023 Orlando, Florida 21-26 February 2023. Vol. 138.Vol. 2. Elsevier. , pp.28-28. (10.1016/j.ymgme.2022.107061)
- Cook, S. R. and Lloyd-Evans, E. 2023. Comparing the lysosomal biotoxicity of iron oxide nanoparticles for improved lysosomal purification. Presented at: 19th Annual WORLDSymposiumTM Orlando, Florida 21-26 February 2023. Vol. 138.Vol. 2. Elsevier. , pp.28-29. (10.1016/j.ymgme.2022.107062)
2022
- Cook, S. 2022. Investigating the impact of metallic nanoparticles on biological systems and lysosomal function. PhD Thesis , Cardiff University.
2020
- Cook, S. R. et al. 2020. Detrimental effect of zwitterionic buffers on lysosomal homeostasis in cell lines and iPSC-derived neurons. AMRC Open Research 2 21. (10.12688/amrcopenres.12903.1)
- Cook, S. R. et al. 2020. Visualisation of cholesterol and ganglioside GM1 in zebrafish models of Niemann-Pick type C disease and Smith-Lemli-Opitz syndrome using light sheet microscopy. Histochemistry and Cell Biology 154 , pp.565-578. (10.1007/s00418-020-01925-2)
Articles
- Best, H. L. et al. 2025. Niemann-Pick C-like endo-lysosomal dysfunction in DHDDS patient cells, a congenital disorder of glycosylation, can be treated with miglustat. International Journal of Molecular Sciences 26 (4) 1471. (10.3390/ijms26041471)
- Cook, S. R. et al. 2020. Detrimental effect of zwitterionic buffers on lysosomal homeostasis in cell lines and iPSC-derived neurons. AMRC Open Research 2 21. (10.12688/amrcopenres.12903.1)
- Cook, S. R. et al. 2020. Visualisation of cholesterol and ganglioside GM1 in zebrafish models of Niemann-Pick type C disease and Smith-Lemli-Opitz syndrome using light sheet microscopy. Histochemistry and Cell Biology 154 , pp.565-578. (10.1007/s00418-020-01925-2)
Conferences
- Cook, S. R. et al. 2023. Investigating lysosomal and cellular phenotypes of the lysosomal disorder cystinosis. Presented at: 19th Annual WORLDSymposium™ 2023 Orlando, Florida 21-26 February 2023. Vol. 138.Vol. 2. Elsevier. , pp.28-28. (10.1016/j.ymgme.2022.107061)
- Cook, S. R. and Lloyd-Evans, E. 2023. Comparing the lysosomal biotoxicity of iron oxide nanoparticles for improved lysosomal purification. Presented at: 19th Annual WORLDSymposiumTM Orlando, Florida 21-26 February 2023. Vol. 138.Vol. 2. Elsevier. , pp.28-29. (10.1016/j.ymgme.2022.107062)
Thesis
- Cook, S. 2022. Investigating the impact of metallic nanoparticles on biological systems and lysosomal function. PhD Thesis , Cardiff University.