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Dr Charlotte Dennison
(hi/ei)
Cydymaith Ymchwil, Is-adran Meddygaeth Seicolegol a Niwrowyddorau Clinigol
Trosolwyg
Rwy'n ymchwilydd ôl-ddoethurol yng Nghanolfan Wolfson ar gyfer Iechyd Meddwl Pobl Ifanc a'r Ganolfan Geneteg a Genomeg Niwroseiciatrig. Mae fy ymchwil presennol yn canolbwyntio ar sail genetig iselder a phryder ymhlith pobl ifanc, ac mae gennyf ddiddordeb arbennig mewn nodi cyfleoedd ar gyfer cyfieithu geneteg glinigol yng nghyd-destun iechyd meddwl.
Cyhoeddiad
2024
- Dennison, C. A., Shakeshaft, A., Eyre, O., Tilling, K., Rice, F. and Thapar, A. 2024. Investigating the neurodevelopmental correlates of early adolescent-onset emotional problems. Journal of Affective Disorders 364, pp. 212-220. (10.1016/j.jad.2024.08.008)
- Tseliou, F. et al. 2024. Childhood correlates and young adult outcomes of trajectories of emotional problems from childhood to adolescence. Psychological Medicine 54(10), pp. 2504-2514. (10.1017/S0033291724000631)
- Riglin, L. et al. 2024. Emotional problems across development: examining measurement invariance across childhood, adolescence and early adulthood. European Child and Adolescent Psychiatry (10.1007/s00787-024-02461-3)
- Shakeshaft, A., Martin, J., Dennison, C. A., Riglin, L., Lewis, C. M., O'Donovan, M. and Thapar, A. 2024. Estimating the impact of transmitted and non-transmitted psychiatric and neurodevelopmental polygenic scores on youth emotional problems. Molecular Psychiatry 29, pp. 238-246. (10.1038/s41380-023-02319-1)
- Dennison, C. et al. 2024. Stratifying early-onset emotional disorders: using genetics to assess persistence in young people of European and South Asian ancestry. Journal of Child Psychology and Psychiatry 65(1), pp. 42-51. (10.1111/jcpp.13862)
2023
- Armitage, J. M. et al. 2023. Validation of the Strengths and Difficulties Questionnaire (SDQ) emotional subscale in assessing depression and anxiety across development. PLoS ONE 18(7), article number: e0288882. (10.1371/journal.pone.0288882)
2022
- Creeth, H. D. J. et al. 2022. Ultrarare coding variants and cognitive function in schizophrenia. JAMA Psychiatry 79(10), pp. 963-970. (10.1001/jamapsychiatry.2022.2289)
- Trubetskoy, V. et al. 2022. Mapping genomic loci prioritises genes and implicates synaptic biology in schizophrenia. Nature 604, pp. 502-508. (10.1038/s41586-022-04434-5)
- Vassos, E. et al. 2022. Lack of support for the genes by early environment interaction hypothesis in the pathogenesis of schizophrenia. Schizophrenia Bulletin 48(1), pp. 20-26. (10.1093/schbul/sbab052)
- Pardinas, A. et al. 2022. Interaction testing and polygenic risk scoring to estimate the contribution of common genetic variants to treatment resistance in schizophrenia. JAMA Psychiatry 79(3), pp. 260-269. (10.1001/jamapsychiatry.2021.3799)
2021
- Dennison, C. et al. 2021. Risk factors, clinical features, and polygenic risk scores in schizophrenia and schizoaffective disorder depressive-type. Schizophrenia Bulletin 47(5), pp. 1375-1384. (10.1093/schbul/sbab036)
- Legge, S. et al. 2021. Associations between schizophrenia polygenic liability, symptom dimensions, and cognitive ability in schizophrenia. JAMA Psychiatry 78(10), pp. 1143-1151. (10.1001/jamapsychiatry.2021.1961)
- Dennison, C. A. et al. 2021. Association of genetic liability for psychiatric disorders with accelerometer-assessed physical activity in the UK Biobank. PLoS ONE 16(3), article number: e0249189. (10.1371/journal.pone.0249189)
- Dennison, C. 2021. Phenotypic and genotypic associations across the psychosis spectrum. PhD Thesis, Cardiff University.
2020
- Legge, S. et al. 2020. Clinical indicators of treatment-resistant psychosis. British Journal of Psychiatry 216(5), pp. 259-266. (10.1192/bjp.2019.120)
- Dennison, C. A., Legge, S. E., Pardinas, A. F. and Walters, J. T. 2020. Genome-wide association studies in schizophrenia: Recent advances, challenges and future perspective. Schizophrenia Research 217, pp. 4-12. (10.1016/j.schres.2019.10.048)
Erthyglau
- Dennison, C. A., Shakeshaft, A., Eyre, O., Tilling, K., Rice, F. and Thapar, A. 2024. Investigating the neurodevelopmental correlates of early adolescent-onset emotional problems. Journal of Affective Disorders 364, pp. 212-220. (10.1016/j.jad.2024.08.008)
- Tseliou, F. et al. 2024. Childhood correlates and young adult outcomes of trajectories of emotional problems from childhood to adolescence. Psychological Medicine 54(10), pp. 2504-2514. (10.1017/S0033291724000631)
- Riglin, L. et al. 2024. Emotional problems across development: examining measurement invariance across childhood, adolescence and early adulthood. European Child and Adolescent Psychiatry (10.1007/s00787-024-02461-3)
- Shakeshaft, A., Martin, J., Dennison, C. A., Riglin, L., Lewis, C. M., O'Donovan, M. and Thapar, A. 2024. Estimating the impact of transmitted and non-transmitted psychiatric and neurodevelopmental polygenic scores on youth emotional problems. Molecular Psychiatry 29, pp. 238-246. (10.1038/s41380-023-02319-1)
- Dennison, C. et al. 2024. Stratifying early-onset emotional disorders: using genetics to assess persistence in young people of European and South Asian ancestry. Journal of Child Psychology and Psychiatry 65(1), pp. 42-51. (10.1111/jcpp.13862)
- Armitage, J. M. et al. 2023. Validation of the Strengths and Difficulties Questionnaire (SDQ) emotional subscale in assessing depression and anxiety across development. PLoS ONE 18(7), article number: e0288882. (10.1371/journal.pone.0288882)
- Creeth, H. D. J. et al. 2022. Ultrarare coding variants and cognitive function in schizophrenia. JAMA Psychiatry 79(10), pp. 963-970. (10.1001/jamapsychiatry.2022.2289)
- Trubetskoy, V. et al. 2022. Mapping genomic loci prioritises genes and implicates synaptic biology in schizophrenia. Nature 604, pp. 502-508. (10.1038/s41586-022-04434-5)
- Vassos, E. et al. 2022. Lack of support for the genes by early environment interaction hypothesis in the pathogenesis of schizophrenia. Schizophrenia Bulletin 48(1), pp. 20-26. (10.1093/schbul/sbab052)
- Pardinas, A. et al. 2022. Interaction testing and polygenic risk scoring to estimate the contribution of common genetic variants to treatment resistance in schizophrenia. JAMA Psychiatry 79(3), pp. 260-269. (10.1001/jamapsychiatry.2021.3799)
- Dennison, C. et al. 2021. Risk factors, clinical features, and polygenic risk scores in schizophrenia and schizoaffective disorder depressive-type. Schizophrenia Bulletin 47(5), pp. 1375-1384. (10.1093/schbul/sbab036)
- Legge, S. et al. 2021. Associations between schizophrenia polygenic liability, symptom dimensions, and cognitive ability in schizophrenia. JAMA Psychiatry 78(10), pp. 1143-1151. (10.1001/jamapsychiatry.2021.1961)
- Dennison, C. A. et al. 2021. Association of genetic liability for psychiatric disorders with accelerometer-assessed physical activity in the UK Biobank. PLoS ONE 16(3), article number: e0249189. (10.1371/journal.pone.0249189)
- Legge, S. et al. 2020. Clinical indicators of treatment-resistant psychosis. British Journal of Psychiatry 216(5), pp. 259-266. (10.1192/bjp.2019.120)
- Dennison, C. A., Legge, S. E., Pardinas, A. F. and Walters, J. T. 2020. Genome-wide association studies in schizophrenia: Recent advances, challenges and future perspective. Schizophrenia Research 217, pp. 4-12. (10.1016/j.schres.2019.10.048)
Gosodiad
- Dennison, C. 2021. Phenotypic and genotypic associations across the psychosis spectrum. PhD Thesis, Cardiff University.
Contact Details
Themâu ymchwil
Arbenigeddau
- Iechyd Meddwl
- Iselder
- Seicosis