Trosolwyg
Crynodeb ymchwil
Mae fy niddordebau ymchwil yn canolbwyntio ar ddatblygu technegau i ymchwilio i ffisioleg yr ymennydd, gan ddefnyddio MRI ac MEG. Mae fy ngwaith yn cynnwys mesur yr ymatebion ffisiolegol i heriau nwy anadledig, gyda'u cymhwysiad i dechnegau fMRI wedi'u graddnodi, ac wrth ddatblygu technegau MRI newydd ar gyfer ymchwilio i brosesau egnïol yr ymennydd, megis ocsimetreg MRI sy'n seiliedig ar dwylledd ac MRI aml-niwclear.
Cyhoeddiad
2024
- Driver, I. D. et al. 2024. Breath-hold calibrated fMRI mapping of absolute cerebral metabolic rate of oxygen metabolism (CMRO2): an assessment of the accuracy and repeatability in a healthy adult population. Imaging Neuroscience 2, pp. 1-14. (10.1162/imag_a_00298)
- Wright, M. E. et al. 2024. OP-07 Retinal and cortical vascular function across the menstrual cycle. Presented at: Women in Vision UK Winter Meeting 2023, Cambridge, UK, 12 December 2023, Vol. 9., (10.1136/bmjoo-2024-WVUK.7)
- McNabb, C. B. et al. 2024. WAND: A multi-modal dataset integrating advanced MRI, MEG, and TMS for multi-scale brain analysis. Scientific Data
2023
- Woodward, O. B., Driver, I., Hart, E. and Wise, R. 2023. In search of a marker of altered cerebrovascular function in hypertension: Analysis of the fractional amplitude of low-frequency fluctuations in UK Biobank resting state fMRI data. Cerebral Circulation - Cognition & Behavior 6, article number: 100196. (10.1016/j.cccb.2023.100196)
- Lancaster, T. et al. 2023. Proof-of-concept recall-by-genotype study of extremely low and high Alzheimer’s polygenic risk reveals autobiographical deficits and cingulate cortex correlates. Alzheimer's Research and Therapy 15, article number: 213. (10.1186/s13195-023-01362-y)
- Woodward, O. B., Driver, I., Schwarz, S. T., Hart, E. and Wise, R. 2023. Assessment of brainstem function and haemodynamics by MRI: challenges and clinical prospects. British Journal of Radiology 96(1151), article number: 20220940. (10.1259/bjr.20220940)
2020
- Rua, C. et al. 2020. Multi-centre, multi-vendor reproducibility of 7T QSM and R2* in the human brain: Results from the UK7T study. NeuroImage 223, article number: 117358. (10.1016/j.neuroimage.2020.117358)
- Bright, M. G., Whittaker, J. R., Driver, I. D. and Murphy, K. 2020. Vascular physiology drives functional brain networks. NeuroImage 217, article number: 116907. (10.1016/j.neuroimage.2020.116907)
- Driver, I. D., Traat, M., Fasano, F. and Wise, R. G. 2020. Most small cerebral cortical veins demonstrate significant flow pulsatility: a human phase contrast MRI study at 7T. Frontiers in Neuroscience 14, article number: 415. (10.3389/fnins.2020.00415)
- Rowland, B. C. et al. 2020. Whole brain 31P MRSI at 7T with a dual-tuned receive array. Magnetic Resonance in Medicine 83(2), pp. 765-775. (10.1002/mrm.27953)
- Clarke, W. T. et al. 2020. Multi-site harmonization of 7 tesla MRI neuroimaging protocols. NeuroImage 206, article number: 116335. (10.1016/j.neuroimage.2019.116335)
- Driver, I. D., Stobbe, R. W., Wise, R. G. and Beaulieu, C. 2020. The venous contribution to sodium MRI in the human brain. Magnetic Resonance in Medicine 83(4), pp. 1331-1338. (10.1002/mrm.27996)
2019
- Whittaker, J., Driver, I., Venzi, M., Bright, M. and Murphy, K. 2019. Cerebral autoregulation evidence by synchronized low frequency oscillations in blood pressure and resing-state fMRI. Frontiers in Neuroscience 13, article number: 433. (10.3389/fnins.2019.00433)
- Wesolowski, R., Blockley, N. P., Driver, I. D., Francis, S. T. and Gowland, P. A. 2019. Coupling between cerebral blood flow and cerebral blood volume: Contributions of different vascular compartments. NMR in Biomedicine, article number: e4061. (10.1002/nbm.4061)
- Whittaker, J. R., Bright, M. G., Driver, I. D., Babic, A., Khot, S. and Murphy, K. 2019. Changes in arterial cerebral blood volume during lower body negative pressure measured with MRI. NeuroImage 187, pp. 166-175. (10.1016/j.neuroimage.2017.06.041)
2017
- Driver, I., Wise, R. and Murphy, K. 2017. Graded hypercapnia-calibrated BOLD: beyond the iso metabolic hypercapnic assumption. Frontiers in Neuroscience 11, article number: 276. (10.3389/fnins.2017.00276)
- Samaraweera, A. P. R. et al. 2017. The central vein sign in multiple sclerosis lesions is present irrespective of the T2* sequence at 3 T. Journal of Neuroimaging 27(1), pp. 114-121. (10.1111/jon.12367)
2016
- Driver, I. D., Whittaker, J. R., Bright, M. G., Muthukumaraswamy, S. and Murphy, K. 2016. Arterial CO2 fluctuations modulate neuronal rhythmicity: Implications for MEG and fMRI studies of resting-state networks. Journal of Neuroscience 36(33), pp. 8541-8550. (10.1523/JNEUROSCI.4263-15.2016)
- Whittaker, J. R., Driver, I. D., Bright, M. G. and Murphy, K. 2016. The absolute CBF response to activation is preserved during elevated perfusion: Implications for neurovascular coupling measures. NeuroImage 125, pp. 198-207. (10.1016/j.neuroimage.2015.10.023)
2015
- Driver, I. D., Andoh, J., Blockley, N. P., Francis, S. T., Gowland, P. A. and Paus, T. 2015. Hemispheric asymmetry in cerebrovascular reactivity of the human primary motor cortex: an in vivo study at 7 T. NMR in Biomedicine 28(5), pp. 538-545. (10.1002/nbm.3282)
- Croal, P. L., Hall, E. L., Driver, I. D., Brookes, M. J., Gowland, P. A. and Francis, S. T. 2015. The effect of isocapnic hyperoxia on neurophysiology as measured with MRI and MEG. Neuroimage 105, pp. 323-331. (10.1016/j.neuroimage.2014.10.036)
2014
- Driver, I. D., Wharton, S. J., Croal, P. L., Bowtell, R., Francis, S. T. and Gowland, P. A. 2014. Global intravascular and local hyperoxia contrast phase-based blood oxygenation measurements. NeuroImage 101, pp. 458-465. (10.1016/j.neuroimage.2014.07.050)
Cynadleddau
- Wright, M. E. et al. 2024. OP-07 Retinal and cortical vascular function across the menstrual cycle. Presented at: Women in Vision UK Winter Meeting 2023, Cambridge, UK, 12 December 2023, Vol. 9., (10.1136/bmjoo-2024-WVUK.7)
Erthyglau
- Driver, I. D. et al. 2024. Breath-hold calibrated fMRI mapping of absolute cerebral metabolic rate of oxygen metabolism (CMRO2): an assessment of the accuracy and repeatability in a healthy adult population. Imaging Neuroscience 2, pp. 1-14. (10.1162/imag_a_00298)
- McNabb, C. B. et al. 2024. WAND: A multi-modal dataset integrating advanced MRI, MEG, and TMS for multi-scale brain analysis. Scientific Data
- Woodward, O. B., Driver, I., Hart, E. and Wise, R. 2023. In search of a marker of altered cerebrovascular function in hypertension: Analysis of the fractional amplitude of low-frequency fluctuations in UK Biobank resting state fMRI data. Cerebral Circulation - Cognition & Behavior 6, article number: 100196. (10.1016/j.cccb.2023.100196)
- Lancaster, T. et al. 2023. Proof-of-concept recall-by-genotype study of extremely low and high Alzheimer’s polygenic risk reveals autobiographical deficits and cingulate cortex correlates. Alzheimer's Research and Therapy 15, article number: 213. (10.1186/s13195-023-01362-y)
- Woodward, O. B., Driver, I., Schwarz, S. T., Hart, E. and Wise, R. 2023. Assessment of brainstem function and haemodynamics by MRI: challenges and clinical prospects. British Journal of Radiology 96(1151), article number: 20220940. (10.1259/bjr.20220940)
- Rua, C. et al. 2020. Multi-centre, multi-vendor reproducibility of 7T QSM and R2* in the human brain: Results from the UK7T study. NeuroImage 223, article number: 117358. (10.1016/j.neuroimage.2020.117358)
- Bright, M. G., Whittaker, J. R., Driver, I. D. and Murphy, K. 2020. Vascular physiology drives functional brain networks. NeuroImage 217, article number: 116907. (10.1016/j.neuroimage.2020.116907)
- Driver, I. D., Traat, M., Fasano, F. and Wise, R. G. 2020. Most small cerebral cortical veins demonstrate significant flow pulsatility: a human phase contrast MRI study at 7T. Frontiers in Neuroscience 14, article number: 415. (10.3389/fnins.2020.00415)
- Rowland, B. C. et al. 2020. Whole brain 31P MRSI at 7T with a dual-tuned receive array. Magnetic Resonance in Medicine 83(2), pp. 765-775. (10.1002/mrm.27953)
- Clarke, W. T. et al. 2020. Multi-site harmonization of 7 tesla MRI neuroimaging protocols. NeuroImage 206, article number: 116335. (10.1016/j.neuroimage.2019.116335)
- Driver, I. D., Stobbe, R. W., Wise, R. G. and Beaulieu, C. 2020. The venous contribution to sodium MRI in the human brain. Magnetic Resonance in Medicine 83(4), pp. 1331-1338. (10.1002/mrm.27996)
- Whittaker, J., Driver, I., Venzi, M., Bright, M. and Murphy, K. 2019. Cerebral autoregulation evidence by synchronized low frequency oscillations in blood pressure and resing-state fMRI. Frontiers in Neuroscience 13, article number: 433. (10.3389/fnins.2019.00433)
- Wesolowski, R., Blockley, N. P., Driver, I. D., Francis, S. T. and Gowland, P. A. 2019. Coupling between cerebral blood flow and cerebral blood volume: Contributions of different vascular compartments. NMR in Biomedicine, article number: e4061. (10.1002/nbm.4061)
- Whittaker, J. R., Bright, M. G., Driver, I. D., Babic, A., Khot, S. and Murphy, K. 2019. Changes in arterial cerebral blood volume during lower body negative pressure measured with MRI. NeuroImage 187, pp. 166-175. (10.1016/j.neuroimage.2017.06.041)
- Driver, I., Wise, R. and Murphy, K. 2017. Graded hypercapnia-calibrated BOLD: beyond the iso metabolic hypercapnic assumption. Frontiers in Neuroscience 11, article number: 276. (10.3389/fnins.2017.00276)
- Samaraweera, A. P. R. et al. 2017. The central vein sign in multiple sclerosis lesions is present irrespective of the T2* sequence at 3 T. Journal of Neuroimaging 27(1), pp. 114-121. (10.1111/jon.12367)
- Driver, I. D., Whittaker, J. R., Bright, M. G., Muthukumaraswamy, S. and Murphy, K. 2016. Arterial CO2 fluctuations modulate neuronal rhythmicity: Implications for MEG and fMRI studies of resting-state networks. Journal of Neuroscience 36(33), pp. 8541-8550. (10.1523/JNEUROSCI.4263-15.2016)
- Whittaker, J. R., Driver, I. D., Bright, M. G. and Murphy, K. 2016. The absolute CBF response to activation is preserved during elevated perfusion: Implications for neurovascular coupling measures. NeuroImage 125, pp. 198-207. (10.1016/j.neuroimage.2015.10.023)
- Driver, I. D., Andoh, J., Blockley, N. P., Francis, S. T., Gowland, P. A. and Paus, T. 2015. Hemispheric asymmetry in cerebrovascular reactivity of the human primary motor cortex: an in vivo study at 7 T. NMR in Biomedicine 28(5), pp. 538-545. (10.1002/nbm.3282)
- Croal, P. L., Hall, E. L., Driver, I. D., Brookes, M. J., Gowland, P. A. and Francis, S. T. 2015. The effect of isocapnic hyperoxia on neurophysiology as measured with MRI and MEG. Neuroimage 105, pp. 323-331. (10.1016/j.neuroimage.2014.10.036)
- Driver, I. D., Wharton, S. J., Croal, P. L., Bowtell, R., Francis, S. T. and Gowland, P. A. 2014. Global intravascular and local hyperoxia contrast phase-based blood oxygenation measurements. NeuroImage 101, pp. 458-465. (10.1016/j.neuroimage.2014.07.050)
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