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David Gillespie
(e/fe)
BSc, PhD
- Ar gael fel goruchwyliwr ôl-raddedig
Timau a rolau for David Gillespie
Prif Gymrawd Ymchwil / Dirprwy Gyfarwyddwr (Canolfan Ymchwil Treialon) / Cyd-gyfarwyddwr (Uned Firoleg Gymhwysol Cymru)
Trosolwyg
Rwy'n Brif Gymrawd Ymchwil ac yn dal dwy rôl arwain o fewn seilwaith Ymchwil Iechyd a Gofal Cymru:
- Dirprwy Gyfarwyddwr y Ganolfan Ymchwil Treialon (CTR).
- Cyd-gyfarwyddwr Uned Firoleg Gymhwysol Cymru (WAVU, https://healthandcareresearchwales.org/about/news/major-investment-research-infrastructure).
Yn fy rôl fel Dirprwy Gyfarwyddwr y CTR, rwy'n darparu uwch arweinyddiaeth ar draws Uned Treialon Clinigol cofrestredig CRC y DU sy'n cynnwys tua 160 o aelodau staff a phortffolio o dros 200 o astudiaethau.
Yn fy rôl fel Cyd-gyfarwyddwr o fewn WAVU, rwy'n arwain y gweithgor thematig Epidemioleg ac Ymarfer Firaol a thrwy'r llwybr hwn rwy'n gyfrifol am sicrhau gweithio rhyngddisgyblaethol ar draws pob gweithgor.
Mae fy nghefndir mewn Ystadegau Meddygol, ac rwyf wedi bod yn gweithio ar ddylunio, cynnal, dadansoddi ac adrodd treialon ar hap ac astudiaethau eraill sydd wedi'u cynllunio'n dda ers 2007. Cwblheais fy PhD ar ddiwedd 2016, gyda fy nhraethawd ymchwil o'r enw "Medication Adherence in Clinical Research and Associated Methodological Challenges".
Yn flaenorol, rwyf wedi dal Cymrodoriaeth Ymchwil Iechyd a ddyfarnwyd gan Ymchwil Iechyd a Gofal Cymru i ymchwilio i'r defnydd o Broffylacsis Cyn Amlygiad (PR) mewn unigolion sydd mewn perygl o gaffael HIV sy'n byw yng Nghymru.
Yn glinigol, mae fy niddordebau ymchwil yn canolbwyntio ar ddefnyddio meddyginiaeth ddarbodus ym maes clefydau heintus, a gellir rhannu fy ngwaith yn fras yn ddau faes allweddol:
- Cadw at feddyginiaeth – yn benodol, ffyrdd y mae ymlyniad at feddyginiaeth yn cael ei gysyniadu, ei fesur a'i fodelu
- Datblygu a gwerthuso ymyriadau stiwardiaeth gwrthficrobaidd
- Datblygu a gwerthuso ymyriadau iechyd y cyhoedd / atal
Mae fy meysydd o ddiddordeb methodolegol yn cynnwys i.) Treialon a methodoleg ymchwil gyffredinol (gwella'r ffyrdd yr ydym yn gwneud hap-dreialon ac astudiaethau eraill sydd wedi'u cynllunio'n dda); ii.) Modelu achosol (dulliau modelu sy'n anelu at ateb cwestiynau achosol, yn hytrach na dim ond cysylltiol); iii.) Data coll (atal a gosod modelau pan fo data ar goll).
Cyhoeddiad
2026
- Pickles, T. et al. 2026. Patient global assessment in rheumatoid arthritis: general health and disease activity are not interchangeable [Letter to the Editor]. Rheumatology 65 (7) keag376. (10.1093/rheumatology/keag376)
- Cochrane, E. et al., 2026. Evaluating PrEP equity in Wales, UK, using triangulation of routine data sources. Sexually Transmitted Infections (10.1136/sextrans-2025-056748)
- Underwood, J. et al. 2026. Risk of dementia after bloodstream infection - a nationwide propensity score matched cohort study. Age and Ageing 55 (6) afag178. (10.1093/ageing/afag178)
- Sheppard, R. et al. 2026. Decision on optimal combinatorial therapies in immune-mediated inflammatory diseases using systems approaches (DocTIS): protocol for a single-arm, adaptive basket trial in rheumatoid and psoriatic arthritis. Rheumatology Advances in Practice 10 (2) rkag036. (10.1093/rap/rkag036)
- Dam, R. et al., 2026. Perceptions and experiences of co‐produced positive behaviour support training in community‐based services and organisations for children with intellectual disabilities and behaviours that challenge: A qualitative multiple case study design. Journal of Applied Research in Intellectual Disabilities 39 (2) e70203. (10.1111/jar.70203)
- Manktelow, N. et al., 2026. Co-production within community-based services for children with intellectual disabilities and behaviours that challenge in England. Tizard Learning Disability Review: Practice, management, research and innovation 31 (1), pp.32-45. (10.1108/tldr-07-2025-0020)
- Kotecha, S. J. et al. 2026. Randomised, double-blind, parallel group, placebo-controlled, trial of Bactek for the prevention of lower respiratory tract infections in preterm infants in the UK: BALLOON study - study protocol. BMJ Open 16 (3) e107929. (10.1136/bmjopen-2025-107929)
- Lowe, J. et al. 2026. Azithromycin therapy for prevention of chronic lung disease of prematurity (AZTEC): a randomised placebo-controlled trial. Health Technology Assessment 30 (12)(10.3310/gjsk0401)
- Aijaz, S. et al., 2026. Differences in sexual risk behaviours, HIV care utilisation and experiences of stigma between transgender women and cisgender men who have sex with men: findings from integrated biobehavioural surveys in Ukraine 2013-2018.. BMJ Open 16 (2) e104918. (10.1136/bmjopen-2025-104918)
2025
- Pickles, T. et al. 2025. Assessing the content validity of patient reported outcome measure item pool for rheumatoid arthritis disease activity using cognitive interviews. Rheumatology 64 (12), pp.6176-6183. keaf421. (10.1093/rheumatology/keaf421)
- Phillips, R. et al., 2025. Are you afraid of COVID-19? Motivation and engagement in infection–prevention behaviour in a UK community cohort during the first 2 years of the COVID-19 pandemic. British Journal of Health Psychology 30 (4) e70034. (10.1111/bjhp.70034)
- Pickles, T. et al. 2025. Patient reported outcome measures for rheumatoid arthritis disease activity: Rasch measurement theory to identify items and domains. Rheumatology 64 (9), pp.4902-4912. (10.1093/rheumatology/keaf189)
- Mathieu, C. et al., 2025. Minimum effective low dose of antithymocyte globulin in people aged 5–25 years with recent-onset stage 3 type 1 diabetes (MELD-ATG): a phase 2, multicentre, double-blind, randomised, placebo-controlled, adaptive dose-ranging trial. The Lancet 406 (10510), pp.1375-1388. (10.1016/s0140-6736(25)01674-5)
- Reeve, N. F. et al. 2025. Risk of myocardial infarction and stroke following microbiologically confirmed urinary tract infection: a self-controlled case series study using linked electronic health data. BMJ Open 15 (6) e097754. (10.1136/bmjopen-2024-097754)
- Gillespie, D. et al. 2025. Influencing factors for the acceptability of accessing HIV pre-exposure prophylaxis via community pharmacies in Wales. Health Expectations 28 (2) e70247. (10.1111/hex.70247)
2024
- Stenfert Kroese, B. et al., 2024. Emotional literacy programme in special schools for children with a learning disability in England: the ZF-SEND feasibility RCT. Public Health Research 12 (15)(10.3310/JTJY8001)
- Sewell, B. et al., 2024. Cost-effectiveness of C-reactive protein point of care testing for safely reducing antibiotic consumption for acute exacerbations of chronic obstructive pulmonary disease as part of the multicentre, parallel-arm, open, individually randomised, controlled PACE trial. BMJ Open 14 (11) e084144. (10.1136/bmjopen-2024-084144)
- Khammas, Z. et al., 2024. HIV Pre‐Exposure Prophylaxis (PrEP) users' experiences of PrEP access, sexual behaviour, and well‐being during the COVID‐19 pandemic: A Welsh qualitative study. Health Expectations 27 (5) e70064. (10.1111/hex.70064)
- Langdon, P. E. et al., 2024. Behavioural interventions to treat anxiety in adults with autism and moderate to severe intellectual disabilities: the BEAMS-ID feasibility study. Health Technology Assessment 28 (72), pp.1-147. (10.3310/mwtq5721)
- Johansen, E. et al., 2024. The optimal antibiotic treatment duration for community-acquired pneumonia in adults diagnosed in general practice in Denmark (CAP-D): an open-label, pragmatic, randomised controlled trial. Trials 25 627. (10.1186/s13063-024-08477-z)
- Langdon, P. E. et al., 2024. Behavioural interventions to treat anxiety in adults with autism and moderate to severe intellectual disabilities: The BEAMS ‐ ID feasibility study. Journal of Applied Research in Intellectual Disabilities 37 (5) e13282. (10.1111/jar.13282)
- Lowe, J. et al. 2024. Azithromycin therapy for prevention of chronic lung disease of prematurity (AZTEC): a multicentre, double-blind, randomised, placebo-controlled trial. The Lancet Respiratory Medicine 12 (8), pp.608-618. (10.1016/S2213-2600(24)00079-1)
- Lowe, J. et al. 2024. Challenges of modulating the risk of bronchopulmonary dysplasia in clinical trials – Authors' reply. The Lancet Respiratory Medicine 12 (8) E44. (10.1016/S2213-2600(24)00173-5)
- Underwood, J. et al. 2024. All-cause and infection-attributable mortality amongst adults with bloodstream infection—a population-based study. Open Forum Infectious Diseases 11 (5) ofae126. (10.1093/ofid/ofae126)
- Gillooly, A. et al., 2024. Behavioural activation for depressive symptoms in adults with severe to profound intellectual disabilities: Modelling and initial feasibility study. Journal of Applied Research in Intellectual Disabilities 37 (2) e13197. (10.1111/jar.13197)
- Randell, E. et al. 2024. Exploring critical intervention features and trial processes in the evaluation of sensory integration therapy for autistic children. BMC Trials 25 (1) 131. (10.1186/s13063-024-07957-6)
- Scior, K. et al., 2024. Digital adaptation of the Standing up for Myself intervention in young people and adults with intellectual disabilities: the STORM feasibility study. Project Report.[Online].National Institute for Health Research. Available at: https://doi.org/10.3310/NCBU6224.
2023
- Taylor, E. L. et al., 2023. Mapping and identifying service models for community-based services for children with intellectual disabilities and behaviours that challenge in England. BMC Health Services Research 23 (1) 1354. (10.1186/s12913-023-10388-9)
- Gillespie, D. et al. 2023. Gut microbiology of UK care home residents: cross-sectional analysis from a randomised controlled trial. Clinical Microbiology and Infection 29 (11), pp.1437-1442. (10.1016/j.cmi.2023.08.001)
- Boateng, I. et al., 2023. Using microbiological data to improve the use of antibiotics for respiratory tract infections: A protocol for an individual patient data meta-analysis. PLoS ONE 18 (11) e0294845. (10.1371/journal.pone.0294845)
- Courtenay, M. , Gillespie, D. and Lim, R. 2023. Patterns of GP and nurse independent prescriber prescriptions for antibiotics dispensed in the community in England: a retrospective analysis. Journal of Antimicrobial Chemotherapy 78 (10), pp.2544-2553. dkad267. (10.1093/jac/dkad267)
- Pickles, T. et al. 2023. Patient reported outcome measures for rheumatoid arthritis disease activity: using Rasch measurement theory and cognitive interviewing to achieve more meaningful measurement [Abstract]. Presented at: ACR Convergence 2023 San Diego 10-15 November 2023. Vol. 75.Vol. Supp 9. Wiley. (10.1002/art.42700)
- Roberts-Tyler, E. J. et al., 2023. Effects of implementation support on children's reading outcomes following an online early reading programme: a cluster-randomised controlled trial. British Journal of Educational Technology 54 (5), pp.1373-1396. (10.1111/bjet.13312)
- Richardson, L. et al., 2023. Standing up for Myself (STORM): Adapting and piloting a web-delivered psychosocial group intervention for people with intellectual disabilities. Research in Developmental Disabilities 137 104496. (10.1016/j.ridd.2023.104496)
- Gillespie, D. et al. 2023. Between- and within-individual sociodemographic and psychological determinants of PrEP adherence among men who have sex with men prescribed a daily PrEP regimen in Wales. AIDS and Behavior 27 , pp.1564-1572. (10.1007/s10461-022-03890-4)
- Lau, T. et al., 2023. Perspectives of statistician, microbiologist, and clinician stakeholders on the use of microbiological outcomes in randomised trials of antimicrobial stewardship interventions. Antibiotics 885. (10.3390/antibiotics12050885)
- Pickles, T. et al. 2023. P035 Patient-reported outcome measures for rheumatoid arthritis disease activity: using Rasch measurement theory to achieve more meaningful measurement. Rheumatology 62 (Supp 2)(10.1093/rheumatology/kead104.076)
- Hounkpatin, H. et al., 2023. Post-consultation acute respiratory tract infection recovery: a latent class informed analysis of individual patient data from randomised controlled trials and observational studies. British Journal of General Practice 73 (728), pp.e196-e203. (10.3399/BJGP.2022.0229)
- Gillespie, D. et al. 2023. Psychometric Properties of an Adapted Stigma Scale and Experiences of Stigma Associated with HIV Pre-exposure Prophylaxis Use Among Men Who have Sex with Men: A Mixed Methods Study. AIDS and Behavior (10.1007/s10461-022-03967-0)
2022
- Evans, A. et al. 2022. Location, location, location: does providing public health services from community pharmacies contribute to tackling health inequalities?. Journal of Public Health fdac148. (10.1093/pubmed/fdac148)
- Phillips, R. et al. 2022. Perceived threat of COVID-19, attitudes towards vaccination, and vaccine hesitancy: A prospective longitudinal study in the UK. British Journal of Health Psychology 27 (4), pp.1354-1381. (10.1111/bjhp.12606)
- Williams, A. D. N. et al. 2022. The relationship between HIV pre-exposure prophylaxis, sexually transmitted infections, and antimicrobial resistance: a qualitative interview study of men who have sex with men. BMC Public Health 22 (1) 2222. (10.1186/s12889-022-14645-0)
- Carvalho, M. J. et al., 2022. Antibiotic resistance genes in the gut microbiota of mothers and linked neonates with or without sepsis from low- and middle-income countries. Nature Microbiology 7 , pp.1337-1347. (10.1038/s41564-022-01184-y)
- Reeve, N. F. et al. 2022. Myocardial infarction and stroke subsequent to urinary tract infection (MISSOURI): protocol for a self-controlled case series using linked electronic health records. BMJ Open 12 e064586. (10.1136/bmjopen-2022-064586)
- Kotecha, S. J. et al. 2022. Follow-up study of infants recruited to the randomised, placebo-controlled trial of azithromycin for the prevention of chronic lung disease of prematurity in preterm infants: study protocol for the AZTEC-FU study. Trials 23 796. (10.1186/s13063-022-06730-x)
- Milton, R. et al. 2022. Incidence and sociodemographic, living environment and maternal health associations with stillbirth in a tertiary healthcare setting in Kano, Northern Nigeria. Short title: Incidence and factors associated with stillbirth in Kano, Nigeria. BMC Pregnancy and Childbirth 22 692. (10.1186/s12884-022-04971-x)
- Gillespie, D. et al. 2022. PrEP use, sexual behaviour, and PrEP adherence among men who have sex with men living in Wales prior to and during the COVID-19 pandemic. AIDS and Behavior 26 , pp.2746-2757. (10.1007/s10461-022-03618-4)
- Lau, T. M. M. et al. 2022. AZTEC—azithromycin therapy for prevention of chronic lung disease of prematurity: a statistical analysis plan for clinical outcomes. Trials 23 (1) 704. (10.1186/s13063-022-06604-2)
- Milosevic, S. et al. 2022. Understanding the support experiences of families of children with autism and sensory processing difficulties: A qualitative study.. Health Expectations 25 (3), pp.1118-1130. (10.1111/hex.13465)
- Randell, E. et al. 2022. Sensory integration therapy for children with autism and sensory processing difficulties: the SenITA RCT. Health Technology Assessment 26 (29)(10.3310/TQGE0020)
- Neill, R. , Gillespie, D. and Ahmed, H. 2022. Variation in antibiotic treatment failure outcome definitions in randomised trials and observational studies of antibiotic pre-scribing strategies: A systematic review and narrative synthesis. Antibiotics 11 (5) 627. (10.3390/antibiotics11050627)
- Pickles, T. et al. 2022. P089 Patient-reported outcome measures for rheumatoid arthritis disease activity: a systematic review following COSMIN guidelines. Presented at: British Society for Rheumatology Annual Conference 2022 Glasgow, Scotland 25-27 April 2022. Rheumatology Supplement 1. Vol. 61., pp.keac133.088. (10.1093/rheumatology/keac133.088)
- Hoult, G. et al. 2022. Biomarkers to guide the use of antibiotics for acute exacerbations of COPD (AECOPD): a systematic review and meta-analysis. BMC Pulmonary Medicine 22 (1) 194. (10.1186/s12890-022-01958-4)
- Gillespie, D. et al. 2022. Experiences of men who have sex with men when initiating, implementing, and persisting with HIV pre-exposure prophylaxis. Health Expectations 25 (4), pp.1332-1341. (10.1111/hex.13446)
- Pickles, T. et al. 2022. Patient reported outcome measures for rheumatoid arthritis disease activity: a systematic review following COSMIN guidelines. RMD Open 8 (1) e002093. (10.1136/rmdopen-2021-002093)
- Lau, T. M. M. et al. 2022. A systematic review investigating the use of microbiology outcome measures in randomized controlled trials evaluating antimicrobial stewardship interventions published between 2011 and 2021. JAC-Antimicrobial Resistance 4 (1) dlac013. (10.1093/jacamr/dlac013)
- Williams, A. et al. 2022. Changing sexual behaviours amongst MSM during the COVID-19 restrictions in Wales: a mixed methods study. BMC Public Health 22 (1) 396. (10.1186/s12889-022-12821-w)
- Segrott, J. et al. 2022. Effectiveness of the strengthening families programme in the UK at preventing substance misuse in 10-14 year-olds: a pragmatic randomised controlled trial. BMJ Open 12 (2) e049647. (10.1136/bmjopen-2021-049647)
- Gillespie, D. et al. 2022. Associations with post-consultation health-status in primary care managed acute exacerbation of COPD. International Journal of Chronic Obstructive Pulmonary Disease 2022 (17), pp.383-394. (10.2147/COPD.S340710)
- Moody, G. et al. 2022. The READ-IT study protocol for a feasibility randomised controlled trial of using a support worker/family carer mediated online reading programme to teach early reading skills to adults with intellectual disabilities. Pilot and Feasibility Studies 8 (1) 13. (10.1186/s40814-022-00972-x)
- Milton, R. et al. 2022. Determinants of stillbirth from two observational studies investigating deliveries in Kano, Nigeria. Frontiers in Global Women's Health 2 788157. (10.3389/fgwh.2021.788157)
2021
- Coulman, E. et al. 2021. Early positive approaches to support (E-PAtS) for families of young children with intellectual disability: a feasibility randomised controlled trial. Frontiers in Psychiatry 12 729129. (10.3389/fpsyt.2021.729129)
- Ahmed, H. , Gillespie, D. and Thomas-Jones, E. 2021. Effect of 7 vs 14 days of antibiotics among afebrile men with urinary tract infection. Journal of the American Medical Association 326 (20) 2080. (10.1001/jama.2021.16738)
- Phillips, R. et al., 2021. Cohort profile: The UK COVID-19 Public Experiences (COPE) prospective longitudinal mixed-methods study of health and well-being during the SARSCoV2 coronavirus pandemic. PLoS ONE 16 (10) e0258484. (10.1371/journal.pone.0258484)
- Read, S. et al. 2021. Normalisation process theory and the implementation of a new glaucoma clinical pathway in hospital eye services: perspectives of doctors, nurses and optometrists. PLoS ONE 16 (8) e0255564. (10.1371/journal.pone.0255564)
- Gillespie, D. et al. 2021. Early impact of COVID-19 social distancing measures on reported sexual behaviour of HIV pre-exposure prophylaxis users in Wales. Sexually Transmitted Infections 97 , pp.85-87. (10.1136/sextrans-2020-054598)
- Butler, C. C. et al., 2021. Probiotics to reduce antibiotic administration in care home residents aged 65 years and older: the PRINCESS RCT. Efficacy and Mechanism Evaluation 8 (7)(10.3310/eme08070)
- Gillespie, D. et al. 2021. Associations with antibiotic prescribing for acute exacerbation of COPD in primary care: secondary analysis of a randomised controlled trial. British Journal of General Practice 71 (705), pp.e266-e272. (10.3399/BJGP.2020.0823)
- Sands, K. et al. 2021. Characterization of antimicrobial resistant Gram-negative bacteria that cause neonatal sepsis in seven low and middle-income countries. Nature Microbiology 6 , pp.512–523. (10.1038/s41564-021-00870-7)
- Stuart, B. et al., 2021. Delayed antibiotic prescribing for respiratory tract infections: an individual patient data meta-analysis. BMJ 372 n808. (10.1136/bmj.n808)
- Castro-Herrera, V. M. et al., 2021. Combination of the probiotics Lacticaseibacillus rhamnosus GG and Bifidobacterium animalis subsp. lactis, BB-12 has limited effect on biomarkers of immunity and inflammation in older people resident in care homes: results from the Probiotics to Reduce Infections iN CarE home reSidentS Randomized, Controlled Trial. Frontiers in Immunology 12 643321. (10.3389/fimmu.2021.643321)
- Felloner, J. et al., 2021. A multi-stakeholder approach to the co-production of the research agenda for medicines optimisation. BMC Health Services Research 21 64. (10.1186/s12913-021-06056-5)
- M.Castro-Herrera, V. et al., 2021. Relationship between age, frailty, length of care home residence and biomarkers of immunity and inflammation in older care residents in the UK. Frontiers in Aging 2 599084. (10.3389/fragi.2021.599084)
2020
- Waterman, H. et al. 2020. Acceptability, adherence and economic analyses of a new clinical pathway for the identification of non-responders to glaucoma eye drops: a prospective observational study. British Journal of Ophthalmology 104 (12), pp.1704-1709. (10.1136/bjophthalmol-2019-315436)
- Francis, N. A. et al., 2020. Clinical features and c-reactive protein as predictors of bacterial exacerbations of COPD. International Journal of Chronic Obstructive Pulmonary Disease 2020 , pp.3147-3158. (10.2147/COPD.S265674)
- Lowe, J. et al. 2020. Study protocol: azithromycin therapy for chronic lung disease of prematurity (AZTEC) - a randomised, placebo-controlled trial of azithromycin for the prevention of chronic lung disease of prematurity in preterm infants. BMJ Open 10 (10) e041528. (10.1136/bmjopen-2020-041528)
- Alghamdi, S. et al. 2020. Prescribing trends over time by non-medical independent prescribers (NMIPs) in primary care settings across Wales (2011-2018): a secondary database analysis. BMJ Open 10 e036379. (10.1136/bmjopen-2019-036379)
- Coulman, E. et al. 2020. The Early Positive Approaches to Support (E-PAtS) study: study protocol for a feasibility cluster randomised controlled trial of a group programme (E-PAtS) for family caregivers of young children with intellectual disability. Pilot and Feasibility Studies 6 (1) 147. (10.1186/s40814-020-00689-9)
- Phillips, R. et al. 2020. C-Reactive Protein-guided antibiotic prescribing for COPD exacerbations: a qualitative evaluation. British Journal of General Practice 70 (696), pp.e505-e523. (10.3399/bjgp20X709865)
- Butler, C. C. et al., 2020. Effect of probiotic use on antibiotic administration among care home residents: a randomized clinical trial. Journal of the American Medical Association 324 (1), pp.47 - 56. (10.1001/jama.2020.8556)
- Lim, R. et al., 2020. Theory-based electronic learning intervention to support appropriate antibiotic prescribing by nurse and pharmacist independent prescribers: an acceptability and feasibility experimental study using mixed methods. BMJ Open 10 (6) e036181. (10.1136/bmjopen-2019-036181)
- Schofield, B. et al., 2020. The feasibility of measuring calprotectin from a throat swab as a marker of infections caused by group A streptococcus: a case–control feasibility study. BJGP Open 4 (2) 20X101006. (10.3399/bjgpopen20X101006)
- Francis, N. A. et al. 2020. C-reactive protein point-of-care testing for safely reducing antibiotics for acute exacerbations of chronic obstructive pulmonary disease: the PACE RCT. Health Technology Assessment 24 15. (10.3310/hta24150)
- Read, S. et al. 2020. Chronic conditions and behavioural change approaches to medication adherence: rethinking clinical guidance and recommendations. Patient Preference and Adherence 14 , pp.581-586. 52446. (10.2147/PPA.S239916)
2019
- Courtenay, M. et al. 2019. A theory-based electronic learning intervention to support appropriate antibiotic prescribing by nurses and pharmacists: intervention development and feasibility study protocol. BMJ Open 9 (8) e028326. (10.1136/bmjopen-2018-028326)
- Butler, C. C. et al. 2019. C-reactive protein testing to guide antibiotic prescribing for COPD exacerbations. New England Journal of Medicine 381 , pp.111-120. (10.1056/NEJMoa1803185)
- Drew, C. J. G. et al. 2019. A protocol for a randomised controlled, double-blind feasibility trial investigating fluoxetine treatment in improving memory and learning impairments in patients with mesial temporal lobe epilepsy: Fluoxetine, Learning and Memory in Epilepsy (FLAME trial). Pilot and Feasibility Studies 5 (1) 87. (10.1186/s40814-019-0474-x)
- Owen-Jones, E. et al. 2019. Protocol for a double-blind placebo-controlled trial to evaluate the efficacy of probiotics in reducing antibiotics for infection in care home residents: the Probiotics to Reduce Infections iN CarE home reSidentS (PRINCESS) trial. BMJ Open 9 (6) e027513. (10.1136/bmjopen-2018-027513)
- Randell, E. et al. 2019. Sensory integration therapy versus usual care for sensory processing difficulties in autism spectrum disorder in children: study protocol for a pragmatic randomised controlled trial.. Trials 20 113. (10.1186/s13063-019-3205-y)
- Stuart, B. et al., 2019. Delayed antibiotic prescribing for respiratory tract infections: protocol of an individual patient data meta-analysis. BMJ Open 9 (1), pp.-. e026925. (10.1136/bmjopen-2018-026925)
- Nollett, C. et al. 2019. Depressive symptoms in people with a vision impairment: A cross-sectional study to identify who is most at risk. BMJ Open 9 (1) e026163. (10.1136/bmjopen-2018-026163)
- Flynn, S. et al., 2019. Who’s challenging who?: A co-produced approach for training staff in learning disability services about challenging behaviour. Tizard Learning Disability Review 24 (4), pp.192-199. (10.1108/TLDR-03-2019-0013)
2018
- Flynn, S. et al., 2018. Is the amount of exposure to aggressive challenging behaviour related to staff work-related 14 well-being in intellectual disability services? Evidence from a clustered research design.. Research in Developmental Disabilities 81 , pp.155-161. (10.1016/j.ridd.2018.04.006)
- Hastings, R. et al., 2018. Who’s challenging who training for staff empathy towards adults with challenging behaviour: cluster randomised controlled trial. Journal of Intellectual Disability Research 62 (9), pp.798-813. (10.1111/jir.12536)
- Gillespie, D. et al. 2018. Use of co-primary outcomes for trials of antimicrobial stewardship interventions. Lancet Infectious Diseases 18 (6), pp.595-597. (10.1016/S1473-3099(18)30289-5)
- Butler, C. C. et al. 2018. Point-of-care urine culture for managing urinary tract infection in primary care: a randomised controlled trial of clinical and cost-effectiveness. British Journal of General Practice 68 (669), pp.e268-e278. (10.3399/bjgp18X695285)
2017
- Butler, C. C. et al. 2017. Variations in presentation, management, and patient outcomes of urinary tract infection: a prospective four-country primary care observational cohort study. British Journal of General Practice 67 (665), pp.e830-e841. (10.3399/bjgp17X693641)
- Segrott, J. et al. 2017. An application of Extended Normalisation Process Theory in a randomised controlled trial of a complex social intervention: process evaluation of the Strengthening Families Programme (10-14) in Wales, UK. SSM - Population Health 3 , pp.255-265. (10.1016/j.ssmph.2017.01.002)
- Courtenay, M. , Gillespie, D. and Lim, R. 2017. Patterns of dispensed non-medical prescriber prescriptions for antibiotics in primary care across England: a retrospective analysis. Journal of Antimicrobial Chemotherapy 72 (10)(10.1093/jac/dkx230)
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- Flynn, S. et al., 2019. Who’s challenging who?: A co-produced approach for training staff in learning disability services about challenging behaviour. Tizard Learning Disability Review 24 (4), pp.192-199. (10.1108/TLDR-03-2019-0013)
- Flynn, S. et al., 2018. Is the amount of exposure to aggressive challenging behaviour related to staff work-related 14 well-being in intellectual disability services? Evidence from a clustered research design.. Research in Developmental Disabilities 81 , pp.155-161. (10.1016/j.ridd.2018.04.006)
- Hastings, R. et al., 2018. Who’s challenging who training for staff empathy towards adults with challenging behaviour: cluster randomised controlled trial. Journal of Intellectual Disability Research 62 (9), pp.798-813. (10.1111/jir.12536)
- Gillespie, D. et al. 2018. Use of co-primary outcomes for trials of antimicrobial stewardship interventions. Lancet Infectious Diseases 18 (6), pp.595-597. (10.1016/S1473-3099(18)30289-5)
- Butler, C. C. et al. 2018. Point-of-care urine culture for managing urinary tract infection in primary care: a randomised controlled trial of clinical and cost-effectiveness. British Journal of General Practice 68 (669), pp.e268-e278. (10.3399/bjgp18X695285)
- Butler, C. C. et al. 2017. Variations in presentation, management, and patient outcomes of urinary tract infection: a prospective four-country primary care observational cohort study. British Journal of General Practice 67 (665), pp.e830-e841. (10.3399/bjgp17X693641)
- Segrott, J. et al. 2017. An application of Extended Normalisation Process Theory in a randomised controlled trial of a complex social intervention: process evaluation of the Strengthening Families Programme (10-14) in Wales, UK. SSM - Population Health 3 , pp.255-265. (10.1016/j.ssmph.2017.01.002)
- Courtenay, M. , Gillespie, D. and Lim, R. 2017. Patterns of dispensed non-medical prescriber prescriptions for antibiotics in primary care across England: a retrospective analysis. Journal of Antimicrobial Chemotherapy 72 (10)(10.1093/jac/dkx230)
- Bates, J. et al. 2017. General practitioner use of a C-reactive protein point-of-care test to help target antibiotic prescribing in patients with acute exacerbations of chronic obstructive pulmonary disease (the PACE study): study protocol for a randomised controlled trial. Trials 18 422. (10.1186/s13063-017-2144-8)
- Gillespie, D. et al. 2017. Determinants of initiation, implementation, and discontinuation of amoxicillin by adults with acute cough in primary care. Patient Preference and Adherence 2017 (11), pp.561-569. (10.2147/PPA.S119256)
- Gillespie, D. et al. 2017. The use of randomisation-based efficacy estimators in non-inferiority trials. Trials 18 (1) 117. (10.1186/s13063-017-1837-3)
- Gillespie, D. et al. 2015. The use of randomisation-based efficacy estimators in non-inferiority trials [Poster Presentation]. Trials 16 (Suppl), pp.P129. (10.1186/1745-6215-16-S2-P129)
- Gillespie, D. et al. 2015. Antibiotic prescribing and associated diarrhoea: a prospective cohort study of care home residents. Age and Ageing 44 (5), pp.853-860. (10.1093/ageing/afv072)
- Simpson, S. A. et al., 2015. A feasibility randomised controlled trial of a motivational interviewing-based intervention for weight loss maintenance in adults. Health Technology Assessment 19 (50)(10.3310/hta19500)
- Gillespie, D. et al. 2015. Adherence-adjusted estimates of benefits and harms from treatment with amoxicillin for LRTI: secondary analysis of a 12-country randomised placebo- controlled trial using randomisation- based efficacy estimators. BMJ Open 5 e006160. (10.1136/bmjopen-2014-006160)
- Hood, K. et al. 2014. Probiotics for Antibiotic-Associated Diarrhoea (PAAD): a prospective observational study of antibiotic-associated diarrhoea (including Clostridium difficile-associated diarrhoea) in care homes. Health Technology Assessment 18 (63)(10.3310/hta18630)
- Gillespie, D. et al. 2014. Electronic monitoring of medication adherence in a 1-year clinical study of 2 dosing regimens of mesalazine for adults in remission with ulcerative colitis. Inflammatory Bowel Diseases 20 (1), pp.82-91. (10.1097/01.MIB.0000437500.60546.2a)
- Segrott, J. et al. 2014. Preventing substance misuse: study protocol for a randomised controlled trial of the Strengthening Families Programme 10-14 UK (SFP 10-14 UK). BMC Public Health 14 (1) 49. (10.1186/1471-2458-14-49)
- Mustafa, M. et al. 2013. Psychological interventions for women with metastatic breast cancer. Cochrane Library 2013 (6) CD004253. (10.1002/14651858.CD004253.pub4)
- Willner, P. et al. 2013. Group-based cognitive-behavioural anger management for people with mild to moderate intellectual disabilities: cluster randomised controlled trial. The British Journal of Psychiatry 203 , pp.288-296. (10.1192/bjp.bp.112.124529)
- Rose, J. et al., 2013. Different factors influence self-reports and third-party reports of anger by adults with intellectual disabilities. Journal of Applied Research in Intellectual Disabilities 26 (5), pp.410-419. (10.1111/jar.12037)
- Allen, D. A. et al. 2012. Continuity of care in the transition from child to adult diabetes services: A realistic evaluation study. Journal of Health Services Research and Policy 17 (3), pp.140-148. (10.1258/jhsrp.2011.011044)
- Butler, C. C. et al. 2012. Effectiveness of multifaceted educational programme to reduce antibiotic dispensing in primary care: practice based randomised controlled trial. British Medical Journal (BMJ) 344 d8173. (10.1136/bmj.d8173)
- Francis, N. A. et al. 2012. Antibiotics for acute cough: an international observational study of patient adherence in primary care. British Journal of General Practice (BJGP) 62 (599), pp.e429-e437. (10.3399/bjgp12X649124)
- Francis, N. A. et al. 2012. Delayed antibiotic prescribing and associated antibiotic consumption in adults with acute cough. British Journal of General Practice (BJGP) 62 (602), pp.e639-e646. (10.3399/bjgp12X654614)
- Hawthorne, A. B. et al. 2012. One-year investigator-blind randomized multicenter trial comparing asacol 2.4 g once daily with 800 mg three times daily for maintenance of remission in ulcerative colitis. Inflammatory Bowel Diseases 18 (10), pp.1885-1893. (10.1002/ibd.21938)
- Hood, K. et al. 2012. Mode of data elicitation, acquisition and response to surveys: a systematic review. Health Technology Assessment 16 (27)(10.3310/hta16270)
- Willner, P. et al., 2011. Anger management for people with mild to moderate learning disabilities: study protocol for a multi-centre cluster randomized controlled trial of a manualized intervention delivered by day-service staff. Trials 12 , pp.36-47. (10.1186/1745-6215-12-36)
- Stanton, N. et al. 2010. Are smokers with acute cough in primary care prescribed antibiotics more often, and to what benefit? An observational study in 13 European countries. European Respiratory Journal 35 (4), pp.761-767. (10.1183/09031936.00168409)
- Butler, C. C. et al. 2009. Variation in antibiotic prescribing and its impact on recovery in patients with acute cough in primary care: prospective study in 13 countries. BMJ 338 b2242. (10.1136/bmj.b2242)
Monograffau
- Scior, K. et al., 2024. Digital adaptation of the Standing up for Myself intervention in young people and adults with intellectual disabilities: the STORM feasibility study. Project Report.[Online].National Institute for Health Research. Available at: https://doi.org/10.3310/NCBU6224.
- McNamara, R. et al. 2017. A pilot randomised controlled trial of community-led ANtipsychotic Drug REduction for Adults with Learning Disabilities. Project Report.[Online].Health Technology Assessment. Available at: https://doi.org/10.3310/hta21470.
- Allen, D. A. et al. 2010. The transition from paediatric to adult diabetes services: what works, for whom and in what circumstances? [Final report. NIHR Service Delivery and Organisation programme]. Project Report.[Online].HMSO. Available at: http://www.netscc.ac.uk/hsdr/files/project/SDO_FR_08-1504-107_V01.pdf.
Ymchwil
Dyfarnwyd >£55m o gyllid grant i mi ar draws 50+ o grantiau, gan gynnwys £3.8m fel ymchwilydd arweiniol a >£8m ar gyfer ymchwil ryngwladol.
Grantiau ymchwil (diweddaraf yn gyntaf):
2025
- Stanton, Parker, and Gillespie et al. Uned Firoleg Gymhwysol Cymru. Ymchwil Iechyd a Gofal Cymru. £3.0M
- Robling ac Adams et al. Canolfan Ymchwil Treialon. Ymchwil Iechyd a Gofal Cymru. £4.7M
2024
- Edwards et al. Graddio gweithgynhyrchu SunPad yn Kenya. Sefydliad Gates. £399K
- Razvi et al. Treial ar hap, dwbl-ddall, a reolir gan placebo i werthuso effeithiolrwydd Triiodothyronine (T3) a weinyddir ar lafar am 24 wythnos mewn cleifion â methiant y galon gyda llai o alldaflu (HFrEF) - Treial TheT3-HF. Cymrodoriaeth EME-Uwch ar y Cyd NIHR / MRC. £2.4M
- Abbott a Thomas-Jones et al. Gwrthfiotigau EXamining ar gyfer Excision Llawfeddygol canser wlseredig skIn (EXCISE). NIHR HTA. £1.5M
- Roberts, Roland, a Cathie et al. Treial ar hap o aminophylline, magnesiwm sylffad neu salbutamol mewnwythiennol
therapi ar gyfer asthma difrifol acíwt mewn plant a phobl ifanc. NIHR HTA. £2.3M - Stoesser et al. Hyd a math o haint y llwybr wrinol, triniaeth gwrthfiotig ac effeithiau ar ficrobiom y perfedd a
resistome (DUTI- GUM). MRC. £674K
2023
- Channon et al. Cwmpasu dichonoldeb datblygu a gwerthuso gwasanaeth cymorth cymheiriaid i bobl sy'n byw gyda HIV yng Nghymru. Iechyd Cyhoeddus Cymru. £32K
- Harding, et al. Paratoadau IntraVESical ar gyfer Atal Heintiau TrAct Wrinol Ailadroddus (Astudiaeth VESPA): treial rhagoriaeth ar hap label agored aml-fraich, aml-safle. NIHR HTA. £2.1M
- Kotecha, et al. Imiwnotherapi mwcosaidd bacteriol ar gyfer atal wheeze mewn babanod a anwyd cynamserol (Treial BALLOON). NIHR / MRC EME. £2.7M
- Edwards, et al. Deunydd hunan-lanhau gyda catalysis ffoto-weithredol: treialon maes yn Nepal. BMGF. £658K.
- Pallmann P a Carrol E, et al. Gwerthusiad ar hap o ganlyniadau clinigol gan ddefnyddio technolegau newydd i optimeiddio therapi gwrthficrobaidd (PROTECT). NIHR HTA. £205K
2022
- Gore N, et al. Treial a Reolir ar Hap Clwstwr o Ddulliau Cadarnhaol Cynnar o Gymorth (E-PAtS) ar gyfer teuluoedd plant ifanc ag anabledd deallusol. NIHR PHR. £1.9M
- Hayward G, Llewelyn M, et al. Effaith hyd therapi gwrthfiotig ar effeithiolrwydd, diogelwch a dewis ymwrthedd i wrthfiotigau mewn menywod sy'n oedolion â heintiau llwybr wrinol (UTI): treial rheoledig ar hap. NIHR HTA. £2.4M
- Channon S, et al. Cwmpasu dichonoldeb datblygu a gwerthuso gwasanaeth cymorth cymheiriaid i bobl sy'n byw gyda HIV yng Nghymru. Iechyd Cyhoeddus Cymru. £32K
- Courtenay M, et al. Ymyrraeth dysgu electronig sy'n seiliedig ar theori i gefnogi presgripsiynu gwrthfiotigau priodol gan ragnodi nyrsys a fferyllwyr: astudiaeth arbrofol derbynioldeb a dichonoldeb. Arloesi i Bawb. £2K
2021
- Jones L, et al. Epidemioleg ac effaith heintiau eilaidd bacteriol ac ymwrthedd gwrthficrobaidd ar Ofal Dwys yn ystod pandemig SARS-CoV-2. Grant Iechyd HCRW. £176K
- Ahmed H, et al. Cnawd Myocardaidd a Strôc Dilynol tO Haint y llwybr Uri (MISSOURI). Grant Ymchwil BHF. £220K
- Nicholls J, Gillespie D. Optimeiddio modelau darparu gwasanaethau Atal HIV a phroffylacsis cyn dod i gysylltiad (PrEP) ar gyfer pob poblogaeth yng Nghaerdydd/Cymru. Gwobr Amser Ymchwil GIG HCRW. £89K
- Stone J, et al. Ffactorau cyd-destun sy'n gyrru trosglwyddiad HIV ymhlith dynion sy'n cael rhyw gyda dynion: Modelu rôl ffactorau ymddygiadol, cymdeithasol a chyfreithiol. Ysgoloriaeth PhD GW4. £66K
- Butler CC, et al. Cyflwyniad, rheoli a chanlyniadau haint RSV mewn oedolion mewn gofal sylfaenol: meta-ddadansoddiad cleifion unigol. Astudiaeth a gychwynnwyd gan ymchwilydd clinigol Janssen. £115K
2020
- Langdon P, et al. Ymyriadau ymddygiadol i drin gorbryder mewn oedolion ag awtistiaeth ac anableddau deallusol cymedrol i ddifrifol (BEAMS – ID). NIHR HTA. £200K
- Hastings R, et al. Mapio a Gwerthuso Gwasanaethau ar gyfer Plant ag Anableddau Dysgu ac Ymddygiadau sy'n Herio (MELD). NIHR HS&DR. £1.2M
- Holmes E, et al. Economeg Diagnosteg Cyflym i Leihau Presgripsiynu Gwrthfiotigau yn GIG Cymru (TRaDe). HCRW HRF. £350K
- Gillespie D, et al. Defnyddio dulliau modelu modern ar gyfer dadansoddi data microbiolegol mewn treialon clinigol o ymyriadau stiwardiaeth gwrthficrobaidd. Ysgol Meddygaeth / Treialon Methodoleg Partneriaeth Ymchwil PhD ysgoloriaeth.
- Phillips R, et al. COVID-19 public experiences in Wales: A longitudinal mixed-methods study of attitudes, beliefs, and behaviour in response to the coronavirus pandemic (COPE Cymru). Galwad Sêr Cymru am ymchwil COVID-19. £130K
- Waterman H, et al. Archwilio rhagdybiaethau, cywirdeb a derbyn dyfais monitro electronig ar gyfer cadw at ddiferion llygaid: astudiaeth label EASY. Cymdeithas Glawcoma Ryngwladol. £30K
2019
- Hood K, et al. Ymchwil Iechyd a Gofal Cymru. Adnewyddu Seilwaith Ymchwil y Ganolfan Treialon. £2.5M
- Stenfert-Kroese B, et al. Astudiaeth ddichonoldeb ar hap o raglen llythrennedd emosiynol yn yr ysgol (Zippy's Friends) ar gyfer plant ag anableddau deallusol (ZIP-SEND). NIHR PHR. £550K
- Scior K, et al. Ymyrraeth grŵp seicogymdeithasol STanding up fOR Myself (STORM) ar gyfer pobl ifanc ac oedolion ag anableddau deallusol: astudiaeth ddichonoldeb. NIHR PHR. £600K
- Marsal S, et al. DocTIS - Penderfyniad ar therapïau cyfunol gorau posibl mewn IMIDs gan ddefnyddio dulliau systemau. H2020. € 7.0M
- Solomon T, et al. Enceph-IG - Imiwnoglobwlin Mewnwythiennol mewn Enseffalitis Awtoimiwn mewn Oedolion: Treial a Reolir gan Placebo Dwbl-ddall ar Hap. NIHR / MRC EME. £2.4M
- Denne L, et al. Addysgu sgiliau darllen cynnar i oedolion ag anableddau deallusol (READ-IT) gan ddefnyddio rhaglen ddarllen ar-lein a gyfryngir gan weithiwr cymorth/gofalwr teulu – astudiaeth ddichonoldeb. NIHR RfPB. £250K
- Pickles T, et al. Adroddodd y claf fesurau canlyniadau ar gyfer difrifoldeb symptomau Arthritis Rhewmatoid. Datblygu prawf addasol cyfrifiadurol o fanc eitemau gan ddefnyddio theori mesur Rasch (SOCRATES). Cymrodoriaeth Doethurol NIHR. £350K
- Gillespie D a Hood K, et al. Deall y berthynas rhwng proffylacsis cyn amlygiad, heintiau a drosglwyddir yn rhywiol, ac ymwrthedd gwrthficrobaidd yng Nghymru. KESS2 Dwyrain. £50K
- Kotecha S, et al. AZithromycin ThErapy ar gyfer clefyd cronig yr ysgyfaint (AZTEC): Treial ar hap, a reolir gan placebo o azithromycin ar gyfer atal clefyd cronig yr ysgyfaint o gynamseredd mewn babanod cynamserol. NIHR HTA. £2.4M
2018
- Gillespie D, et al. Datblygu ymyrraeth i wneud y gorau o'r defnydd o broffylacsis cyn amlygiad (PrEP) i atal caffael HIV mewn unigolion sydd mewn perygl sy'n byw yng Nghymru (DO-PrEP). Cymrodoriaeth Ymchwil Iechyd a Gofal Cymru. £430K
- Walsh T, et al. Baich Ymwrthedd i Wrthfiotigau mewn Newydd-anedig o Gymdeithasau sy'n Datblygu - Dadansoddiadau Epidemiolegol a Genomig Rhwydwaith BARNARDS. Sefydliad Bill a Melinda Gates. £600K
2017
- Jahoda A, et al. Actifadu ymddygiadol (BeatIt) ar gyfer iselder mewn oedolion ag anableddau deallusol difrifol. Astudiaeth reoledig ar hap dichonoldeb o BeatIt yn erbyn triniaeth fel arfer. Cronfa Elusennol Baily Thomas. £100K
- Hastings R, et al. Dulliau Cadarnhaol Cynnar o Gymorth (E-PAtS) ar gyfer teuluoedd plant ifanc ag anabledd deallusol: Astudiaeth ddichonoldeb. NIHR PHR. £500K
- Courtenay M et al. Ymyrraeth ar gyfer presgripsiynwyr gofal sylfaenol i gefnogi'r dewis a'r defnydd o wrthfiotigau. ESRC IAA. £20K
- Rosser A, et al. Dyluniadau treialon ar gyfer cyflwyno therapïau newydd ar gyfer niwroddirywiad (TRIDENT). £220K
- Waterman H, et al. Dichonoldeb a Derbynioldeb Llwybr Clinigol newydd ar gyfer Adnabod Diferion Llygaid Glawcoma (yr astudiaeth TRIAGE). Ymchwil Iechyd a Gofal Cymru RfPPB. £225K
2015
- Butler CC, et al. Probiotegau i leihau heintiau mewn preswylwyr cartrefi gofal (PRINCESS). NIHR / MRC EME. £1.9M
- McNamara R, et al. Treial rheoledig ar hap pragmatig o therapi integreiddio synhwyraidd yn erbyn gofal arferol ar gyfer anawsterau prosesu synhwyraidd mewn anhwylder sbectrwm awtistiaeth mewn plant, a'i effaith ar anawsterau ymddygiadol, sgiliau addasu a chymdeithasu (SenITA). NIHR HTA. £1.5M
2014
- Butler CC a Francis NA, et al. Meddyg Teulu (Meddyg Teulu) yn defnyddio Prawf Pwynt Gofal Protein C-Adweithiol (CRP) (POCT) i helpu i dargedu presgripsiynu gwrthfiotigau i gleifion ag Exacerbations Acíwt o Glefyd Rhwystrol Cronig yr Ysgyfaint (AECOPD) sy'n fwyaf tebygol o elwa (PACE). NIHR HTA. £1.4M
2013
- Kerr M, et al. Lleihau cyffuriau gwrth-seicotig dan arweiniad y gymuned ar gyfer oedolion ag anableddau dysgu: treial a reolir gan placebo dwbl-ddall ar hap (ANDREA-LD). £1.5M
Addysgu
Addysgu
- Ers 2023, rwyf wedi rhoi darlith gwadd gwadd ar gyfer Modiwl Meistr mewn Treialon Clinigol Iechyd y Cyhoedd Coleg Prifysgol Dulyn o'r enw "Dylunio a dadansoddi hapdreialon ymyriadau stiwardiaeth gwrthfiotigau".
- Ers 2019/2020, rwyf wedi traddodi darlith ar "Hapdreialon strategaethau triniaeth i helpu i wella rhagnodi gwrthfiotigau a chanlyniadau cysylltiedig â haint" ar gyfer Modiwl Amodau Aciwt y BSc Rhyng-gyfrifedig Iechyd Poblogaeth.
- Yn ystod blynyddoedd academaidd 2018/2019 a 2019/2020 cynhaliais sesiynau ar ddatblygu protocolau astudio fel rhan o'r modiwl Dulliau Ymchwil 2 ar gyfer myfyrwyr BSc Rhyng-gyfrifedig Meddygol
- Ym mis Mehefin 2016, fe wnes i gyd-ddatblygu a chyflwyno cwrs tridiau ar ddadansoddi data sylfaenol gan ddefnyddio'r iaith rhaglennu ystadegol R (o'r enw "dysgwr") i staff ym Mhrifysgol Namibia fel rhan o Brosiect Phoenix (http://www.cardiff.ac.uk/phoenix-project)
- Yn flaenorol, rwyf wedi dysgu meintiau grwpiau bach a chanolig ar lefel israddedig ac ôl-raddedig ar bynciau gan gynnwys dulliau ymchwil meintiol, ystadegau, ac arfarniad beirniadol
Arolygiaeth
- Yn flaenorol, rwyf wedi goruchwylio myfyrwyr israddedig ac ôl-raddedig yn yr Ysgol Meddygaeth, Ysgol Fferylliaeth, a'r Ysgol Mathemateg, a'r Ysgol Seicoleg (ym Mhrifysgol Caerfaddon) ar bynciau megis agweddau methodolegol ar werthuso ymyriadau stiwardiaeth gwrthficrobaidd, defnyddio meddyginiaeth a chadw meddyginiaeth, a HIV-stigma.
Rwyf wedi goruchwylio'r myfyrwyr PhD canlynol i'w cwblhau:
Adam Williams (goruchwyliwr arweiniol): Deall y berthynas rhwng PrEP, STIs, ac AMR yng Nghymru
Timothy Pickles (cyd-oruchwyliwr): Mesurau canlyniadau a adroddir gan gleifion ar gyfer difrifoldeb symptom arthritis gwynegol: datblygu prawf addasol cyfrifiadurol o fanc eitem gan ddefnyddio theori mesur Rasch
Mandy Lau (goruchwyliwr cyd-arweiniol): Defnyddio dulliau modelu modern ar gyfer dadansoddi ystadegol data microbiolegol mewn treialon clinigol ymyriadau stiwardiaeth gwrthficrobaidd (https://www.cardiff.ac.uk/people/view/362467-lau-mandy)
Ar hyn o bryd rwy'n goruchwylio'r myfyrwyr PhD cofrestredig canlynol:
Saher Aijaz Khan (cyd-oruchwyliwr, dan arweiniad Prifysgol Bryste): Ffactorau sy'n benodol i gyd-destun sy'n gyrru trosglwyddiad HIV ymhlith dynion sy'n cael rhyw gyda dynion: Modelu rôl ffactorau ymddygiadol, cymdeithasol a chyfreithiol (https://gw4biomed.ac.uk/cohort-6/)
Eskild Johansen (cyd-oruchwyliwr, dan arweiniad Prifysgol Aalborg): Y cyfnod triniaeth gwrthfiotig gorau posibl ar gyfer niwmonia a gaffaelir yn y gymuned mewn oedolion a ddiagnosiwyd mewn practis cyffredinol yn Nenmarc: treial rheoledig ar hap label agored, pragmatig, ar hap (https://vbn.aau.dk/en/persons/142036)
Helen Russell (cyd-oruchwyliwr, dan arweiniad Prifysgol Bryste): Ymchwilio i ysbytai sy'n benodol i achos ymhlith pobl sy'n byw gyda HIV ar therapi gwrth-retrofirol (https://research-information.bris.ac.uk/en/persons/helen-p-russell)
Bywgraffiad
Addysg a chymwysterau:
- 2013 - 2016: PhD "Medication Adherence in Clinical Research and Associated Methodological Challenges" (Ysgol Meddygaeth) Prifysgol Caerdydd, Caerdydd, DU
- 2005 - 2009: BSc mewn Mathemateg, Ymchwil Weithredol ac Ystadegau (Ysgol Mathemateg) Prifysgol Caerdydd, Caerdydd, DU (gyda blwyddyn lleoliad)
Trosolwg gyrfa:
- Tachwedd 2025 - Presennol: Dirprwy Gyfarwyddwr, Canolfan Ymchwil Treialon, Prifysgol Caerdydd
- Ebrill 2025 - Presennol: Cyd-gyfarwyddwr, Uned Firoleg Gymhwysol Cymru, Prifysgol Caerdydd
- Hydref 2022 - Ionawr 2026: Cyfarwyddwr Treialon Heintiau, Llid ac Imiwnedd, Canolfan Ymchwil Treialon, Prifysgol Caerdydd
- Awst 2022 - Presennol: Prif Gymrawd Ymchwil, Canolfan Ymchwil Treialon, Prifysgol Caerdydd
- Ebrill 2020 - Gorffennaf 2022: Uwch Gymrawd Ymchwil, Canolfan Ymchwil Treialon, Prifysgol Caerdydd
- Ebrill 2020 - Medi 2022: Uwch Gymrawd Ymchwil mewn Ystadegau Meddygol, Adran Gwyddorau Iechyd Gofal Sylfaenol Nuffield, Is-adran y Gwyddorau Meddygol, Prifysgol Rhydychen (secondiad rhan-amser)
- Mai 2018 - Mawrth 2020: Dirprwy Gyfarwyddwr Treialon Heintiau, Llid ac Imiwnedd ac Uwch Gymrawd Ymchwil, Canolfan Ymchwil Treialon, Prifysgol Caerdydd
- Rhagfyr 2016 - Mai 2018: Cymrawd Ymchwil mewn Ystadegau, Canolfan Ymchwil Treialon, Prifysgol Caerdydd
- Hydref 2015 - Mawrth 2016: Ymgynghorydd Methodolegol, Gwasanaeth Dylunio a Chynnal Ymchwil, Prifysgol Caerdydd (secondiad rhan-amser)
- Awst 2015 - Tachwedd 2016: Cydymaith Ymchwil mewn Ystadegau, Canolfan Ymchwil Treialon, Prifysgol Caerdydd
- Mawrth 2012 - Tachwedd 2016: Cydymaith Ymchwil mewn Ystadegau, Uned Treialon De-ddwyrain Cymru, Prifysgol Caerdydd
- Mehefin 2009 - Mawrth 2012: Ystadegydd Iau, Uned Treialon De-ddwyrain Cymru, Prifysgol Caerdydd
- Gorffennaf 2007 - Medi 2008: Ystadegydd dan Hyfforddiant, Uned Treialon De-ddwyrain Cymru, Prifysgol Caerdydd
Anrhydeddau a dyfarniadau
- Derbyn gwobr am Oruchwylydd Ymchwil Ôl-raddedig y Flwyddyn yr Ysgol Meddygaeth (2023)
- Enwebwyd ar gyfer Gwobr Dathlu Rhagoriaeth Prifysgol Caerdydd yng nghategori "Rising Star" (2016)
- Wedi derbyn Gwobr Cyfraniad Eithriadol gan Brifysgol Caerdydd (2016)
- Derbyn gwobr ar ôl graddio am ennill y radd uchaf ar draws yr Ysgol Mathemateg am fy nhraethawd hir BSc (2009)
Pwyllgorau ac adolygu
Pwyllgorau allanol
- Aelod presennol o'r bwrdd ar gyfer Pwyllgor Comisiynu HTA NIHR
- Arweinydd Ymchwil a Gwerthuso ar gyfer Fast Track Cymru (https://fasttrack.wales/about/)
- Aelod o Bwyllgor Goruchwylio Cynllun Gweithredu HIV Llywodraeth Cymru
- Pwyllgor Llywio Treial Annibynnol Cyfredol / Aelod Pwyllgor Monitro Data Annibynnol ar gyfer: PROMPPT, BLIPA, ATHENA, ADDEWID, GWELLA, LLEIHAU 2, COT, BROGA, A NEOGASTRIC.
- Arweinydd Academaidd blaenorol ar gyfer Ymgysylltu â Rhanddeiliaid yn Treialon Cymru (https://www.cardiff.ac.uk/centre-for-trials-research/about-us/treialon-cymru)
- Arweinydd Ymchwil a Gwerthuso blaenorol ar gyfer Llwybr Cyflym Caerdydd a'r Fro (https://fasttrackcardiff.wales/)
- Aelod o bwyllgor Grŵp Diddordeb Arbennig Gofal Iechyd Sylfaenol y Gymdeithas Ystadegol Frenhinol (2011 i 2014)
- Aelod blaenorol o'r bwrdd ar gyfer panel Ymchwil ar gyfer Cleifion a Budd Cyhoeddus Ymchwil i Gleifion a Gofal Cymru (RfPPB) (2016 i 2019)
- Aelod blaenorol o'r bwrdd cyswllt ar gyfer NIHR HTA (2019 i 2021)
- Aelod annibynnol blaenorol ar gyfer nifer o TSCs ac IDMCs
- Aelod blaenorol o Grŵp Gorchwyl a Gorffen Cynllun Gweithredu HIV Llywodraeth Cymru
adolygydd cymheiriaid
- Rwy'n Olygydd Cyswllt ar gyfer Treialon
- Rwy'n aelod o'r Bwrdd Cynghori Ystadegol ar gyfer BMJ Open
- Golygydd ymgynghori blaenorol mewn ystadegau ar gyfer y Journal of Intellectual Disabilities Research.
- Yn flaenorol yn Olygydd Gwadd Argraffiad Arbennig ar gyfer y cyfnodolyn Antibiotics.
- Rwy'n adolygu cyflwyniadau i The Lancet (a chyfnodolion cysylltiedig), BMJ Open (aelod o'r bwrdd cynghori ystadegol), Journal of Infection Prevention Research, Research in Developmental Disabilities, Trials, JAIDS, AIDS and Behavior, Respiratory Medicine, a Patient Preference and Adlynence. Rwyf hefyd yn adolygu ceisiadau am gyllid ac adroddiadau terfynol ar gyfer paneli amrywiol ar draws NIHR, MRC, a HCRW.
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Contact Details
[email protected]
+44 29206 87610
Neuadd Meirionnydd, Ystafell 503, Ysbyty Athrofaol Cymru, Parc y Mynydd Bychan, Caerdydd, CF14 4YS
+44 29206 87610
Neuadd Meirionnydd, Ystafell 503, Ysbyty Athrofaol Cymru, Parc y Mynydd Bychan, Caerdydd, CF14 4YS
Themâu ymchwil
Arbenigeddau
- Ymchwil clinigol cymhwysol
- Treialon Clinigol
- Iechyd y cyhoedd
- Afiechydon heintus
