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Dr Irina Guschina
Timau a rolau for Irina Guschina
Cymrawd Ymchwil
Biowyddorau Moleciwlaidd
Trosolwg
Mae Dr. Irina Guschina yn cael ei chydnabod yn rhyngwladol am ymchwil i rôl lipidau mewn systemau byw. Wedi'i uno gan fewnwelediadau manwl i strwythur lipidau, swyddogaethau a metaboledd mewn gwahanol gyd-destunau, mae ei gwaith yn cwmpasu: i) pwysigrwydd lipidau mewn iechyd a chlefydau; ii) dylanwad lipidau ar swyddogaeth ecosystemau; a iii) eu rôl mewn rhyngweithiadau troffig mewn ymateb i newid byd-eang.
Mae ei diddordebau hefyd yn ymestyn i gymwysiadau strategol fel arwyddocâd lipidau a nodweddion asid brasterog wrth synthesis biodanwyddau cynaliadwy, er enghraifft o algâu.
Gyda dros 100 o gyhoeddiadau gwyddonol mewn cyfnodolion neu lyfrau rhyngwladol, dyfynnir ei chyfraniadau yn eang (H = 38;
bron i 5,810 o ddyfyniadau).
Yn y DU, mae cymorth ymchwil wedi cynnwys sefydliadau blaenllaw gan gynnwys y Gymdeithas Frenhinol, tra bod gwaith tramor wedi'i ariannu gan gyrff ymchwil cenedlaethol, er enghraifft yn yr Almaen, De Affrica a Chile.
Mae cyfraniad at addysgu a mentora yn cynnwys myfyrwyr israddedig ac ôl-raddedig ar bob cam.
Mae cyfranogiad yn y gymuned wyddonol ehangach yn cynnwys gweithgareddau dyfarnu mynych, er enghraifft fel dyfarnwr i'r Journal of Applied Phycology, Phytochemistry, Lipids in Health and Disease, Marine Druds, Fuel, Bioresource Technology, Foods, PLOS ONE, Frontiers in Plant Science, Molecules ac eraill.
Cyhoeddiad
2026
- Michael, D. R. et al., 2026. The impact of three distinct probiotic supplements on the gut microbiota and its metabolites in healthy adults. Beneficial Microbes 17 , pp.221-234. (10.1163/18762891-bja00096)
- Hornsby, A. K. et al. 2026. The 5:2 diet induces male-specific weight loss and sex-independent enhancement of lipid storage in mice via activation of GHSR. Frontiers in Nutrition 13 1735869. (10.3389/fnut.2026.1735869)
- Alalawi, S. et al., 2026. Anti-atherogenic actions of pomegranate polyphenol punicalagin and its metabolites: In vitro effects on vascular cells and in vivo atheroprotection by urolithin A via anti-inflammatory and plaque-stabilising mechanisms. Antioxidants 15 (4) 507. (10.3390/antiox15040507)
2025
- Smith, K. A. et al. 2025. Helminth-induced prostaglandin signalling and dietary shifts in PUFA metabolism promote colitis-associated cancer. Journal of Lipid Research 66 (7) 100837. (10.1016/j.jlr.2025.100837)
2023
- Richter, F. C. et al., 2023. Adipocyte autophagy limits gut inflammation by controlling oxylipin and IL‐10. The EMBO Journal , pp.e112202. (10.15252/embj.2022112202)
2022
- Palyzová, A. , Guschina, I. A. and Řezanka, T. 2022. Chiral analysis of glycerol phosphates - Can bacteria biosynthesize heterochiral phospholipid membranes?. Journal of Chromatography A 1676 463267. (10.1016/j.chroma.2022.463267)
2021
- Guschina, I. A. and Harwood, J. L. 2021. Chemical diversity of lipids. In: Encyclopedia of Biophysics. Springer(10.1007/978-3-642-35943-9_526-1)
- Guschina, I. A. et al. 2021. Triple-knockout, synuclein-free mice display compromised lipid pattern. Molecules 26 (11) 3078. (10.3390/molecules26113078)
2020
- Guschina, I. A. , Hayes, A. J. and Ormerod, S. J. 2020. Polystyrene microplastics decrease accumulation of essential fatty acids in common freshwater algae. Environmental Pollution 263 (PartB) 114425. (10.1016/j.envpol.2020.114425)
2019
- Woodfield, H. K. et al. 2019. Increase in lysophosphatidate acyltransferase activity in oilseed rape (Brassica napus) increases seed triacylglycerol content despite its low intrinsic flux control coefficient. New Phytologist 224 (2), pp.700-711. (10.1111/nph.16100)
- Gallagher, H. et al. 2019. Dihimo-γ-linolenic acid inhibits several key cellular processes associated with atherosclerosis. BBA - Molecular Basis of Disease 1865 (9), pp.2538-2550. (10.1016/j.bbadis.2019.06.011)
2018
- Guschina, I. A. and Harwood, J. L. 2018. Strategies for the analysis of plant lipids. In: Encyclopedia of Analytical Chemistry. John Wiley & Sons, Ltd.(10.1002/9780470027318.a9920.pub2)
- Pope, I. et al. 2018. Coherent Raman Scattering microscopy: technology developments and biological applications. Presented at: 20th International Conference on Transparent Optical Networks (ICTON) Bucharest, Romania 1-5 Jul 2018. 20th International Conference on Transparent Optical Networks (ICTON). IEEE. (10.1109/ICTON.2018.8473706)
- Woodfield, H. K. et al. 2018. Using lipidomics to reveal details of lipid accumulation in developing seeds from oilseed rape (Brassica napus L.). Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids 1863 (3)(10.1016/j.bbalip.2017.12.010)
2017
- Woodfield, H. K. et al. 2017. Spatial and temporal mapping of key lipid species in Brassica napus seeds. Plant Physiology 173 (4), pp.1998-2009. (10.1104/pp.16.01705)
- Hopkins, A. L. et al., 2017. Unacylated ghrelin promotes adipogenesis in rodent bone marrow via ghrelin O-acyl transferase and GHS-R1a activity: evidence for target-cell-induced acylation. Scientific Reports 7 45541. (10.1038/srep45541)
- Golding, D. M. et al. 2017. Paradoxical leanness in the imprinting-centre deletion mouse model for Prader–Willi syndrome. Journal of Endocrinology 232 (1), pp.123-135. (10.1530/JOE-16-0367)
2016
- Bascoul-Colombo, C. et al., 2016. Dietary DHA supplementation causes selective changes in phospholipids from different brain regions in both wild type mice and the Tg2576 mouse model of Alzheimer's disease. Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids 1861 (6), pp.524-537. (10.1016/j.bbalip.2016.03.005)
- Wacker, A. et al., 2016. Light-induced changes in fatty acid profiles of specific lipid classes in several freshwater phytoplankton species. Frontiers in Plant Science 7 264. (10.3389/fpls.2016.00264)
2015
- Guschina, I. et al. 2015. Erratum to ‘Studies on the regulation of lipid biosynthesis in plants: Application of control analysis to soybean’ [Biochim. Biophys. Acta 1838 (2014) 1488–1500]. Biochimica et Biophysica Acta (BBA) - Biomembranes 1848 (1), pp.104. (10.1016/j.bbamem.2014.10.011)
- Tsurkan, Y. et al., 2015. Identification of newly-isolated microorganisms containing valuable polyunsaturated fatty acids. Journal of Biotech Research 6 , pp.14-20.
2014
- Willis, G. R. et al. 2014. Young women with polycystic ovary syndrome have raised levels of circulating annexin V-positive platelet microparticles. Human Reproduction 29 (12), pp.2756-2763. (10.1093/humrep/deu281)
- Connolly, K. D. et al. 2014. Lipoprotein-apheresis reduces circulating microparticles in individuals with familial hypercholesterolemia. Journal of Lipid Research 55 , pp.2064-2072. (10.1194/jlr.M049726)
- Guschina, I. et al. 2014. Studies on the regulation of lipid biosynthesis in plants: application of control analysis to soybean. Biochimica et Biophysica Acta (BBA) - Biomembranes 1838 (6), pp.1488-1500. (10.1016/j.bbamem.2014.02.008)
- Ramli, U. S. et al., 2014. Informed metabolic engineering of oil crops using control analysis. Biocatalysis and Agricultural Biotechnology 3 (1), pp.49-52. (10.1016/j.bcab.2013.12.001)
- Koussoroplis, A. et al., 2014. Famine and feast in a common freshwater calanoid: effects of diet and temperature on fatty acid dynamics of Eudiaptomus gracilis. Limnology and Oceanography 59 (3), pp.947-958. (10.4319/lo.2014.59.3.0947)
- Steiner, T. et al., 2014. Protective role for properdin in progression of experimental murine atherosclerosis. PLoS ONE 9 (3) e92404. (10.1371/journal.pone.0092404)
2013
- Berube, K. A. et al. 2013. Exposure and harm to combustion-derived particles: Searching for biomarkers. Presented at: European Aerosol Conference 2013 Prague, Czech Republic 1-6 September 2013.
- Harwood, J. L. and Guschina, I. 2013. Regulation of lipid synthesis in oil crops. FEBS Letters 587 (13), pp.2079-2081. (10.1016/j.febslet.2013.05.018)
- Harwood, J. L. et al. 2013. Regulation and enhancement of lipid accumulation in oil crops: The use of metabolic control analysis for informed genetic manipulation. European Journal of Lipid Science and Technology 115 (11), pp.1239-1246. (10.1002/ejlt.201300257)
- Millership, S. et al., 2013. Correction for Millership et al., Increased lipolysis and altered lipid homeostasis protect -synuclein-null mutant mice from diet-induced obesity. Proceedings of the National Academy of Sciences of the United States of America 110 (13), pp.5269. (10.1073/pnas.1302920110)
- Randall, J. et al. 2013. Endemic infection reduces transmission potential of an epidemic parasite during co-infection. Proceedings of the Royal Society B: Biological Sciences 280 (1769) 20131500. (10.1098/rspb.2013.1500)
2012
- Wells, T. et al. 2012. Opa3, a novel regulator of mitochondrial function, controls thermogenesis and abdominal fat mass in a mouse model for Costeff syndrome. Human Molecular Genetics 21 (22), pp.4836-4844. (10.1093/hmg/dds315)
- Elphick, L. M. et al., 2012. Conserved valproic-acid-induced lipid droplet formation in Dictyostelium and human hepatocytes identifies structurally active compounds. Disease Models & Mechanisms 5 (2), pp.231-240. (10.1242/dmm.008391)
- Falinska, A. M. et al. 2012. The role of n-3 dietary polyunsaturated fatty acids in brain function and ameliorating Alzheimer's disease: Opportunities for biotechnology in the development of nutraceuticals. Biocatalysis and Agricultural Biotechnology 1 (2), pp.159-166. (10.1016/j.bcab.2011.09.001)
- Millership, S. et al. 2012. Increased lipolysis and altered lipid homeostasis protect γ-synuclein–null mutant mice from diet-induced obesity. Proceedings of the National Academy of Sciences of the United States of America 109 (51), pp.20943-20948. (10.1073/pnas.1210022110)
- Tang, M. et al. 2012. Metabolic control analysis of developing oilseed rape (Brassica napus cv Westar) embryos shows that lipid assembly exerts significant control over oil accumulation. New Phytologist 196 (2), pp.414-426. (10.1111/j.1469-8137.2012.04262.x)
2011
- Guschina, I. et al. 2011. Lipid classes and fatty acid patterns are altered in the brain of γ-synuclein null mutant mice. Lipids 46 (2), pp.121-130. (10.1007/s11745-010-3486-0)
- Fuschino, J. et al. 2011. Rising water temperatures alter lipid dynamics and reduce n-3 essential fatty acid concerntrations in Scenedesmus obliquus (chlorophyta). Journal of Phycology 47 (4), pp.763-774. (10.1111/j.1529-8817.2011.01024.x)
- Lewis, R. D. et al. 2011. CD55 deficiency protects against atherosclerosis in ApoE-deficient mice via C3a modulation of lipid metabolism. American Journal of Pathology 179 (4), pp.1601-1607. (10.1016/j.ajpath.2011.06.015)
- McLaren, J. E. et al. 2011. Eicosapentaenoic acid and docosahexaenoic acid regulate modified LDL uptake and macropinocytosis in human macrophages. Lipids 46 (11), pp.1053-1061.
2010
- Yang, X. et al., 2010. The action of herbicides on fatty acid biosynthesis and elongation in barley and cucumber. Pest management Science 66 (7), pp.794-800. (10.1002/ps.1944)
2009
- Davies, J. S. et al. 2009. Ghrelin induces abdominal obesity via GHS-R-dependent lipid retention. Molecular Endocrinology 23 (6), pp.914-924. (10.1210/me.2008-0432)
- Guschina, I. et al. 2009. The microaerophilic flagellate, Trichomonas vaginalis, contains unusual acyl lipids but no detectable cardiolipin. Journal of Eukaryotic Microbiology 56 (1), pp.52-57. (10.1111/j.1550-7408.2008.00365.x)
- Harwood, J. L. and Guschina, I. 2009. The versatility of algae and their lipid metabolism. Biochimie 91 (6), pp.679-684. (10.1016/j.biochi.2008.11.004)
2008
- Hernandez, M. L. et al., 2008. The utilization and desaturation of oleate and linoleate during glycerolipid biosynthesis in olive (Olea europaea L.) callus cultures. Journal of Experimental Botany 59 (9), pp.2425-2435. (10.1093/jxb/ern121)
2007
- Markman, S. et al., 2007. Endocrine disrupting chemicals accumulate in earthworms exposed to sewage effluent. Chemosphere 70 (1), pp.119-125. (10.1016/j.chemosphere.2007.06.045)
2006
- Sayanova, O. et al., 2006. A bifunctional Δ12,Δ15-Desaturase from Acanthamoeba castellanii directs the synthesis of highly unusual n-1 series unsaturated fatty acids. Journal of Biological Chemistry 281 (48), pp.36533-36541. (10.1074/jbc.M605158200)
Adrannau llyfrau
- Guschina, I. A. and Harwood, J. L. 2021. Chemical diversity of lipids. In: Encyclopedia of Biophysics. Springer(10.1007/978-3-642-35943-9_526-1)
- Guschina, I. A. and Harwood, J. L. 2018. Strategies for the analysis of plant lipids. In: Encyclopedia of Analytical Chemistry. John Wiley & Sons, Ltd.(10.1002/9780470027318.a9920.pub2)
Cynadleddau
- Pope, I. et al. 2018. Coherent Raman Scattering microscopy: technology developments and biological applications. Presented at: 20th International Conference on Transparent Optical Networks (ICTON) Bucharest, Romania 1-5 Jul 2018. 20th International Conference on Transparent Optical Networks (ICTON). IEEE. (10.1109/ICTON.2018.8473706)
- Berube, K. A. et al. 2013. Exposure and harm to combustion-derived particles: Searching for biomarkers. Presented at: European Aerosol Conference 2013 Prague, Czech Republic 1-6 September 2013.
Erthyglau
- Michael, D. R. et al., 2026. The impact of three distinct probiotic supplements on the gut microbiota and its metabolites in healthy adults. Beneficial Microbes 17 , pp.221-234. (10.1163/18762891-bja00096)
- Hornsby, A. K. et al. 2026. The 5:2 diet induces male-specific weight loss and sex-independent enhancement of lipid storage in mice via activation of GHSR. Frontiers in Nutrition 13 1735869. (10.3389/fnut.2026.1735869)
- Alalawi, S. et al., 2026. Anti-atherogenic actions of pomegranate polyphenol punicalagin and its metabolites: In vitro effects on vascular cells and in vivo atheroprotection by urolithin A via anti-inflammatory and plaque-stabilising mechanisms. Antioxidants 15 (4) 507. (10.3390/antiox15040507)
- Smith, K. A. et al. 2025. Helminth-induced prostaglandin signalling and dietary shifts in PUFA metabolism promote colitis-associated cancer. Journal of Lipid Research 66 (7) 100837. (10.1016/j.jlr.2025.100837)
- Richter, F. C. et al., 2023. Adipocyte autophagy limits gut inflammation by controlling oxylipin and IL‐10. The EMBO Journal , pp.e112202. (10.15252/embj.2022112202)
- Palyzová, A. , Guschina, I. A. and Řezanka, T. 2022. Chiral analysis of glycerol phosphates - Can bacteria biosynthesize heterochiral phospholipid membranes?. Journal of Chromatography A 1676 463267. (10.1016/j.chroma.2022.463267)
- Guschina, I. A. et al. 2021. Triple-knockout, synuclein-free mice display compromised lipid pattern. Molecules 26 (11) 3078. (10.3390/molecules26113078)
- Guschina, I. A. , Hayes, A. J. and Ormerod, S. J. 2020. Polystyrene microplastics decrease accumulation of essential fatty acids in common freshwater algae. Environmental Pollution 263 (PartB) 114425. (10.1016/j.envpol.2020.114425)
- Woodfield, H. K. et al. 2019. Increase in lysophosphatidate acyltransferase activity in oilseed rape (Brassica napus) increases seed triacylglycerol content despite its low intrinsic flux control coefficient. New Phytologist 224 (2), pp.700-711. (10.1111/nph.16100)
- Gallagher, H. et al. 2019. Dihimo-γ-linolenic acid inhibits several key cellular processes associated with atherosclerosis. BBA - Molecular Basis of Disease 1865 (9), pp.2538-2550. (10.1016/j.bbadis.2019.06.011)
- Woodfield, H. K. et al. 2018. Using lipidomics to reveal details of lipid accumulation in developing seeds from oilseed rape (Brassica napus L.). Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids 1863 (3)(10.1016/j.bbalip.2017.12.010)
- Woodfield, H. K. et al. 2017. Spatial and temporal mapping of key lipid species in Brassica napus seeds. Plant Physiology 173 (4), pp.1998-2009. (10.1104/pp.16.01705)
- Hopkins, A. L. et al., 2017. Unacylated ghrelin promotes adipogenesis in rodent bone marrow via ghrelin O-acyl transferase and GHS-R1a activity: evidence for target-cell-induced acylation. Scientific Reports 7 45541. (10.1038/srep45541)
- Golding, D. M. et al. 2017. Paradoxical leanness in the imprinting-centre deletion mouse model for Prader–Willi syndrome. Journal of Endocrinology 232 (1), pp.123-135. (10.1530/JOE-16-0367)
- Bascoul-Colombo, C. et al., 2016. Dietary DHA supplementation causes selective changes in phospholipids from different brain regions in both wild type mice and the Tg2576 mouse model of Alzheimer's disease. Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids 1861 (6), pp.524-537. (10.1016/j.bbalip.2016.03.005)
- Wacker, A. et al., 2016. Light-induced changes in fatty acid profiles of specific lipid classes in several freshwater phytoplankton species. Frontiers in Plant Science 7 264. (10.3389/fpls.2016.00264)
- Guschina, I. et al. 2015. Erratum to ‘Studies on the regulation of lipid biosynthesis in plants: Application of control analysis to soybean’ [Biochim. Biophys. Acta 1838 (2014) 1488–1500]. Biochimica et Biophysica Acta (BBA) - Biomembranes 1848 (1), pp.104. (10.1016/j.bbamem.2014.10.011)
- Tsurkan, Y. et al., 2015. Identification of newly-isolated microorganisms containing valuable polyunsaturated fatty acids. Journal of Biotech Research 6 , pp.14-20.
- Willis, G. R. et al. 2014. Young women with polycystic ovary syndrome have raised levels of circulating annexin V-positive platelet microparticles. Human Reproduction 29 (12), pp.2756-2763. (10.1093/humrep/deu281)
- Connolly, K. D. et al. 2014. Lipoprotein-apheresis reduces circulating microparticles in individuals with familial hypercholesterolemia. Journal of Lipid Research 55 , pp.2064-2072. (10.1194/jlr.M049726)
- Guschina, I. et al. 2014. Studies on the regulation of lipid biosynthesis in plants: application of control analysis to soybean. Biochimica et Biophysica Acta (BBA) - Biomembranes 1838 (6), pp.1488-1500. (10.1016/j.bbamem.2014.02.008)
- Ramli, U. S. et al., 2014. Informed metabolic engineering of oil crops using control analysis. Biocatalysis and Agricultural Biotechnology 3 (1), pp.49-52. (10.1016/j.bcab.2013.12.001)
- Koussoroplis, A. et al., 2014. Famine and feast in a common freshwater calanoid: effects of diet and temperature on fatty acid dynamics of Eudiaptomus gracilis. Limnology and Oceanography 59 (3), pp.947-958. (10.4319/lo.2014.59.3.0947)
- Steiner, T. et al., 2014. Protective role for properdin in progression of experimental murine atherosclerosis. PLoS ONE 9 (3) e92404. (10.1371/journal.pone.0092404)
- Harwood, J. L. and Guschina, I. 2013. Regulation of lipid synthesis in oil crops. FEBS Letters 587 (13), pp.2079-2081. (10.1016/j.febslet.2013.05.018)
- Harwood, J. L. et al. 2013. Regulation and enhancement of lipid accumulation in oil crops: The use of metabolic control analysis for informed genetic manipulation. European Journal of Lipid Science and Technology 115 (11), pp.1239-1246. (10.1002/ejlt.201300257)
- Millership, S. et al., 2013. Correction for Millership et al., Increased lipolysis and altered lipid homeostasis protect -synuclein-null mutant mice from diet-induced obesity. Proceedings of the National Academy of Sciences of the United States of America 110 (13), pp.5269. (10.1073/pnas.1302920110)
- Randall, J. et al. 2013. Endemic infection reduces transmission potential of an epidemic parasite during co-infection. Proceedings of the Royal Society B: Biological Sciences 280 (1769) 20131500. (10.1098/rspb.2013.1500)
- Wells, T. et al. 2012. Opa3, a novel regulator of mitochondrial function, controls thermogenesis and abdominal fat mass in a mouse model for Costeff syndrome. Human Molecular Genetics 21 (22), pp.4836-4844. (10.1093/hmg/dds315)
- Elphick, L. M. et al., 2012. Conserved valproic-acid-induced lipid droplet formation in Dictyostelium and human hepatocytes identifies structurally active compounds. Disease Models & Mechanisms 5 (2), pp.231-240. (10.1242/dmm.008391)
- Falinska, A. M. et al. 2012. The role of n-3 dietary polyunsaturated fatty acids in brain function and ameliorating Alzheimer's disease: Opportunities for biotechnology in the development of nutraceuticals. Biocatalysis and Agricultural Biotechnology 1 (2), pp.159-166. (10.1016/j.bcab.2011.09.001)
- Millership, S. et al. 2012. Increased lipolysis and altered lipid homeostasis protect γ-synuclein–null mutant mice from diet-induced obesity. Proceedings of the National Academy of Sciences of the United States of America 109 (51), pp.20943-20948. (10.1073/pnas.1210022110)
- Tang, M. et al. 2012. Metabolic control analysis of developing oilseed rape (Brassica napus cv Westar) embryos shows that lipid assembly exerts significant control over oil accumulation. New Phytologist 196 (2), pp.414-426. (10.1111/j.1469-8137.2012.04262.x)
- Guschina, I. et al. 2011. Lipid classes and fatty acid patterns are altered in the brain of γ-synuclein null mutant mice. Lipids 46 (2), pp.121-130. (10.1007/s11745-010-3486-0)
- Fuschino, J. et al. 2011. Rising water temperatures alter lipid dynamics and reduce n-3 essential fatty acid concerntrations in Scenedesmus obliquus (chlorophyta). Journal of Phycology 47 (4), pp.763-774. (10.1111/j.1529-8817.2011.01024.x)
- Lewis, R. D. et al. 2011. CD55 deficiency protects against atherosclerosis in ApoE-deficient mice via C3a modulation of lipid metabolism. American Journal of Pathology 179 (4), pp.1601-1607. (10.1016/j.ajpath.2011.06.015)
- McLaren, J. E. et al. 2011. Eicosapentaenoic acid and docosahexaenoic acid regulate modified LDL uptake and macropinocytosis in human macrophages. Lipids 46 (11), pp.1053-1061.
- Yang, X. et al., 2010. The action of herbicides on fatty acid biosynthesis and elongation in barley and cucumber. Pest management Science 66 (7), pp.794-800. (10.1002/ps.1944)
- Davies, J. S. et al. 2009. Ghrelin induces abdominal obesity via GHS-R-dependent lipid retention. Molecular Endocrinology 23 (6), pp.914-924. (10.1210/me.2008-0432)
- Guschina, I. et al. 2009. The microaerophilic flagellate, Trichomonas vaginalis, contains unusual acyl lipids but no detectable cardiolipin. Journal of Eukaryotic Microbiology 56 (1), pp.52-57. (10.1111/j.1550-7408.2008.00365.x)
- Harwood, J. L. and Guschina, I. 2009. The versatility of algae and their lipid metabolism. Biochimie 91 (6), pp.679-684. (10.1016/j.biochi.2008.11.004)
- Hernandez, M. L. et al., 2008. The utilization and desaturation of oleate and linoleate during glycerolipid biosynthesis in olive (Olea europaea L.) callus cultures. Journal of Experimental Botany 59 (9), pp.2425-2435. (10.1093/jxb/ern121)
- Markman, S. et al., 2007. Endocrine disrupting chemicals accumulate in earthworms exposed to sewage effluent. Chemosphere 70 (1), pp.119-125. (10.1016/j.chemosphere.2007.06.045)
- Sayanova, O. et al., 2006. A bifunctional Δ12,Δ15-Desaturase from Acanthamoeba castellanii directs the synthesis of highly unusual n-1 series unsaturated fatty acids. Journal of Biological Chemistry 281 (48), pp.36533-36541. (10.1074/jbc.M605158200)
Ymchwil
Diddordebau Ymchwil:
- Moleciwlau Biolegol Actif
- Lipidau, asidau brasterog, pigmentau, gwrthocsidyddion mewn iechyd a chlefydau
- Biocemeg a Bioleg Moleciwlaidd Asidau Brasterog Anarferol
- Mechamismau Biocemegol a Moleciwlaidd Addasiadau i'r Amgylchedd
- Bioleg System
- Rheoleiddio Synthesis Lipid a Thrin Metabolig
- Biotechnoleg lipidau ac asidau brasterog
- Biodanwydd/Algâu Biodanwydd
Profiad Technegol:
- Planhigion / Micro-organebau / Celloedd a Meinweoedd
- Dadansoddiad Lipid, Pigment a Gwrthocsidiol
- Bioleg Moleciwlaidd: Dadansoddi a Mynegiant Genynnau sy'n Gysylltiedig â Biosynthesis Lipid
- Adnabod Strwythurol a Meintioli Cyfansoddion Naturiol gan ddefnyddio Cromatograffeg Haen Denau a Cholofn gyda Systemau Canfod Amrywiol (ee, UV, Radio-, ELSD)
- GC-MS; HPLC-MS / MS
- Lipidomeg
Addysgu
Addysgu yn y meysydd gwyddonol canlynol:
- Dulliau Ymchwil mewn Bioleg Lipidau
- Metaboledd lipid uwch
- Rheoli Fflwcs Metabolig
Bywgraffiad
Lleoliad presennol
- 2005 - presennol: Cymrawd Ymchwil, Ysgol Biowyddoniaeth Caerdydd, Prifysgol Caerdydd, DU
Swyddi blaenorol
- 1988-2002: Cymrawd Ymchwil, Sefydliad Ecoleg Basn Afon Volga, Academi Gwyddorau Rwsia, Togliatty, Rwsia
- 1999: Ymchwilydd Gwadd DAAD, Prifysgol Regensburg, yr Almaen
- 2002: Ymchwilydd Gwadd, Prifysgol KwaZulu-Natal, Pietermaritzburg, De Affrica
- 2002-2005: Cydymaith Ymchwil, Ysgol y Biowyddorau Caerdydd, Prifysgol Caerdydd, DU
Addysg
- 1991-1996: PhD, Adran Biocemeg, Prifysgol Talaith Sankt-Petersburg, Sankt-Petersburg, Rwsia
- 1985-1988: Adran Embryoleg a Geneteg, Prifysgol Talaith Samara, Samara, Rwsia
- 1982-1985: Adran Cemeg a Bioleg, Prifysgol Talaith Samara, Samara, Rwsia
Contact Details
Themâu ymchwil
Arbenigeddau
- Lipids
- asidau brasterog
- addasu i'r amgylchedd
- Effeithiau ac addasu newid hinsawdd
- rheoleiddio metabolig